Abstract:
OBJECTIVES:Cilostazol improves walking in patients with peripheral arterial disease (PAD). We hypothesized that cilostazol reduces diabetic complications in PAD patients. METHODS:Diabetic PAD patients were prospectively recruited to a randomized double-blinded, placebo-controlled trial, using cilostazol 100mg twice a day. Clinical assessment included ankle-brachial index, arterial compliance, peripheral transcutaneous oxygenation, treadmill walking distance and validated quality of life (QoL) questionnaires. Biochemical analyses included glucose and lipid profiles. All tests were at baseline, 6, and 24 weeks. RESULTS:26 diabetic PAD patients (20 men) were recruited. Cilostazol improved absolute walking distance at 6 and 24 weeks (86.4% vs. 14.1%, P = .049; 143% vs. 23.2%, P = .086). Arterial compliance and lipid profiles improved as did some QoL indices for cilostazol at 6 and 24 weeks. Blood indices were similar at baseline and at follow-up points for both treatment groups. CONCLUSIONS:Cilostazol is a well-tolerated and efficacious treatment, which improves claudication distances in diabetic PAD patients with further benefits in arterial compliance, lipid profiles, and QoL.
journal_name
Vasc Endovascular Surgjournal_title
Vascular and endovascular surgeryauthors
O'Donnell ME,Badger SA,Sharif MA,Makar RR,Young IS,Lee B,Soong CVdoi
10.1177/1538574408328586subject
Has Abstractpub_date
2009-04-01 00:00:00pages
132-43issue
2eissn
1538-5744issn
1938-9116pii
1538574408328586journal_volume
43pub_type
杂志文章,随机对照试验abstract::Aneurysmal degeneration after peripheral angioplasty is a potentially serious complication. In this case, the patient underwent repeated angioplasty of a prior vein bypass graft utilizing a paclitaxel-coated balloon. He subsequently developed a progressive aneurysmal degeneration, threatening his bypass, which ultimat...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574420978104
更新日期:2020-12-16 00:00:00
abstract::Strategies developed by vascular surgeons to establish an endovascular program and the 5-year results of the program are reported. In 1994, the operating room was chosen as the site for the endovascular suite. With this strategy, vascular surgeons would be able to 1) govern appropriate indications for intervention, 2)...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/153857440203600104
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Tissue loss or gangrene in the setting of lower extremity peripheral artery disease (PAD) may result in amputation. Previous studies have demonstrated elevated mortality rates after major transtibial and transfemoral amputation. Also, amputation of 1 leg may be associated with subsequent major amputation of ...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574413503715
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:When critical limb ischemia (CLI) occurs in patients with thromboangiitis obliterans (TAO) or Buerger's disease, smoking cessation alone may be insufficient to relieve rest pain and promote wound healing. Accordingly, adjunctive measures are warranted to restore adequate blood flow required for limb salvage. Th...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
doi:10.1177/1538574417744085
更新日期:2018-02-01 00:00:00
abstract::The technical success of an endovascular abdominal aortic aneurysm repair depends on the endograft exclusion of the aneurysm along with preservation of flow to major aortic branches, such as the renal or hypogastric artery. A proximally malpositioned aortic endograft may result in inadvertent renal artery occlusion, w...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/153857440403800109
更新日期:2004-01-01 00:00:00
abstract::The objective of this study was to evaluate the clinical and duplex outcome after carotid endarterectomy (CEA) in recently symptomatic patients aged 80 years or older. Information was assembled from a prospective data collection of all CEAs performed from January 1986 to December 1999. Included were all patients with ...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/153857440203600601
更新日期:2002-11-01 00:00:00
abstract::Internal iliac artery aneurysms are a rare variant of aorto-iliac aneurysm disease. They are associated with high mortality if managed conservatively. Open surgery is associated with significant morbidity and mortality especially when performed for rupture. Endovascular stent coverage after feeding vessel embolization...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574410369387
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND AND IMPORTANCE:High-flow spontaneous vertebral arteriovenous shunts in patients with fibromuscular disease (FMD) are rare. Onyx embolization of the recipient veins with shunt disconnection and preservation of the affected vertebral artery in a patient with FMD has not been reported. CLINICAL PRESENTATION:A ...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574412452156
更新日期:2012-08-01 00:00:00
abstract::This study evaluated the learning curve for a second-year general surgery resident and compared 2 totally laparoscopic aortic surgery techniques in 10 pigs: the transretroperitoneal apron approach and the transperitoneal retrocolic approach. Five end points were compared: success rate, percentage of conversion, time r...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574407299800
更新日期:2007-06-01 00:00:00
abstract::Anatomical variations of the digestive system arteries are important due to their clinical significance. However, anomalies in the inferior mesenteric artery (IMA) are the least common compared with the celiac trunk and superior mesenteric artery. This report describes the case of a 67-year-old man with an extremely r...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574412445217
更新日期:2012-07-01 00:00:00
abstract::Medline was searched for studies investigating the perioperative and long-term results that derive from statin use in patients with abdominal aortic aneurysm and the clinical and experimental evidence dealing with aneurysm expansion. Data suggest that statins improve the perioperative and long-term outcomes of aneurys...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574407308205
更新日期:2008-04-01 00:00:00
abstract::Abnormal aortic arch anatomy is relatively uncommon but most frequently involves an aberrant right subclavian artery. Rarely, it is associated with aneurysmal dilatation of a chronic type B dissection. Under such circumstances, the abnormal anatomy may complicate therapeutics options. Furthermore, controversy exists r...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574408328662
更新日期:2009-06-01 00:00:00
abstract::In this study, the effect of heparin-derived oligosaccharide on bovine vascular smooth muscle cell (VSMC) proliferation and signal transduction mechanism was investigated. Extracellular-signal-regulated kinase (ERK) 1/2 has been implicated in the regulation of various cellular functions including proliferation, and we...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574412442595
更新日期:2012-07-01 00:00:00
abstract::The aim of this study was to report the results of high-energy endovenous laser treatment to measure the relationship between the fluence and the outcome in terms of recanalization. In 97 patients, 129 great saphenous veins were treated with endovenous laser treatment, using a 980-nm diode laser. Follow-up visits were...
journal_title:Vascular and endovascular surgery
pub_type: 临床试验,杂志文章
doi:10.1177/1538574407311107
更新日期:2008-04-01 00:00:00
abstract::Aneurysms of the superior mesenteric artery (SMA) are an uncommon but lethal entity, which must be treated expeditiously to avoid mortality and high incidence of ischemic small bowel complications. In the past 7 years the authors have treated 4 patients with a variety of types of aneurysms involving the SMA and its br...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/153857440303700108
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:Patients referred for fenestrated/branched endovascular aortic repair (F/BEVAR) often present with a previous computed tomography angiogram (CTA), but it is unknown how recent the CTA must be to ensure accurate F/BEVAR planning. We sought to determine whether anatomic planning parameters change significantly...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574419864769
更新日期:2019-10-01 00:00:00
abstract::Because of its extremely powerful sclerosing effect, in our experience, ethanol can be considered the most efficacious agent in the percutaneous treatment of peripheral venous malformations. To reduce the risk of ethanol reflux into the superficial veins or the central venous system, we developed a simple but very eff...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574410362117
更新日期:2010-05-01 00:00:00
abstract::Patients with chronic occlusion of iliac veins may present with symptoms ranging from mild discomfort to severe disability, including limb swelling, venous claudication, and ulceration. Endovascular treatment has emerged as first line of interventional therapy. Surgical venous-venous bypasses for the management of the...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574412454584
更新日期:2012-10-01 00:00:00
abstract::Iliac artery tortuosity can be a limiting factor in treating abdominal aortic aneurysms by endovascular means. In this case, a 6F catheter guiding sheath was used to allow tracking of the superstiff wire to straighten the iliac artery on the left. This allowed for tracking of the larger sheath so that a bifurcated dev...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574410369569
更新日期:2010-08-01 00:00:00
abstract::Vascular Ehlers-Danlos syndrome (vEDS) is a life-threatening connective tissue disorder due to its high tendency of arterial and organ rupture. Pulmonary complications in vEDS are rare. We present a young male patient with vEDS who developed severe pulmonary complications and severe rupture of the iliac artery at diff...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
doi:10.1177/1538574417745432
更新日期:2018-02-01 00:00:00
abstract:AIM:The aim of the study is to determine whether presentation and outcomes of inflammatory abdominal aortic aneurysms (IAAA) have changed over the last five decades. METHODS:Comparison of current outcomes (January 2001 to December 2007) with results of the earliest report from our unit in 1972. RESULTS:In contemporar...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574409335915
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Regression of the residual sac is indicative of successful endovascular aortic aneurysm (EVAR) repair. Using color duplex ultrasound (CDU), we monitored the residual aneurysm sac following EVAR and correlated sac behavior with perioperative risk factors. METHODS:Of 145 patients with EVAR, 106 (73.1%) patien...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574413513846
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:Vascular closure device (VCD) use following antegrade femoral access may present unique challenges relative to retrograde access. We retrospectively compared safety and efficacy of these devices between antegrade and retrograde patient cohorts undergoing percutaneous intervention. MATERIALS AND METHODS:Over a ...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574420941298
更新日期:2020-10-01 00:00:00
abstract::Cerebral reperfusion following carotid endarterectomy occasionally causes cerebral hyperperfusion syndrome. This is a rare but important complication and this case report acted as a stimulus for a literature review of this problem. A 60-year-old businessman had a right carotid endarterectomy for a severe stenosis whic...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
doi:10.1177/153857440203600407
更新日期:2002-07-01 00:00:00
abstract::Lower extremity vascular injuries following trauma are rare events that require prompt identification and management in order to prevent ischemia and limb loss. Endovascular approaches, rather than traditional open procedures, are increasingly used to treat a wide range of vascular disease. The use of endovascular rep...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
doi:10.1177/1538574420954576
更新日期:2021-02-01 00:00:00
abstract:PURPOSE:Treatment options after arteriovenous fistula (AVF) associated steal include ligation, banding, and distal revascularization-interval ligation (DRIL). The purpose of this study was to evaluate the arterial pressure gradients in upper extremity steal syndrome. METHODS:Preoperative arteriography and sequential i...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574410376450
更新日期:2010-11-01 00:00:00
abstract::Isolated aneurysms of the internal iliac artery (IIIAA) represent a rare pathology. The application of endovascular therapy has been shown to reduce both mortality and blood loss. We present a case of an isolated left internal iliac artery aneurysm treated with a hybrid approach. A 92-year-old male was found to have a...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574409345027
更新日期:2009-12-01 00:00:00
abstract::Arteriovenous (AV) loop grafts are a type of vascular conduit that can be used to support free tissue transfer. Wounds of various etiologies may require free tissue transfer, and the AV loop graft is a useful adjunct when adjacent blood supply is inadequate. Here we present 2 cases and review the technique and publish...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
doi:10.1177/1538574411418843
更新日期:2012-01-01 00:00:00
abstract:UNLABELLED:Revascularization of patients with intermittent claudication (IC) is recommended only for selected patients who have chronic pain or disabling disease. However, improvement in the quality of life (QoL) could justify more widespread use. OBJECTIVES:To determine the effect of conservative treatment and revasc...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574410376602
更新日期:2011-02-01 00:00:00
abstract::Ischemic stroke due to an acute occlusion of the extracranial internal carotid artery (eICA) is associated with high morbidity and mortality. The best treatment option remains unclear. This study aims to increase the available therapeutic experience documented for surgical recanalization of acute eICA occlusions. We r...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574418800131
更新日期:2019-01-01 00:00:00