Are statins an option in the management of abdominal aortic aneurysms?

Abstract:

:Medline was searched for studies investigating the perioperative and long-term results that derive from statin use in patients with abdominal aortic aneurysm and the clinical and experimental evidence dealing with aneurysm expansion. Data suggest that statins improve the perioperative and long-term outcomes of aneurysm operations and may also reduce expansion rates. International guidelines recommend the use of statins in these patients because abdominal aortic aneurysms are considered as a coronary heart disease equivalent. These guidelines do not appear to have been widely implemented. Preliminary results suggest that statins might play a role in the management of abdominal aortic aneurysms. Verification of these results in large-scale trials may hold implications for a more comprehensive approach of patients with abdominal aortic aneurysms as well as population-wide aneurysm screening programs. Irrespective of the role of statins on aneurysm expansion rates, it is important to ensure that all abdominal aortic aneurysm patients receive statin therapy to improve perioperative and long-term morbidity and mortality.

journal_name

Vasc Endovascular Surg

authors

Paraskevas KI,Liapis CD,Hamilton G,Mikhailidis DP

doi

10.1177/1538574407308205

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

128-34

issue

2

eissn

1538-5744

issn

1938-9116

pii

42/2/128

journal_volume

42

pub_type

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