Global transcriptional profiling reveals Streptococcus agalactiae genes controlled by the MtaR transcription factor.

abstract：BACKGROUND:In contrast to unidirectional promoters wherein antisense transcription results in short transcripts which are rapidly degraded, bidirectional promoters produce mature transcripts in both sense and antisense orientation. To understand the molecular mechanism of how productive bidirectional transcription is r...

journal_title：BMC genomics

authors： Jangid RK,Kelkar A,Muley VY,Galande S

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Aquaculture is the quickest growing sector in agriculture. However, QTL for important traits have been only identified in a few aquaculture species. We conducted QTL mapping for growth traits in an Asian seabass F(2) family with 359 individuals using 123 microsatellites and 22 SNPs, and performed association...

journal_title：BMC genomics

authors： Xia JH,Lin G,He X,Liu P,Liu F,Sun F,Tu R,Yue GH

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Loaches of Cobitinae, widely distributed in Eurasian continent, have high economic, ornamental and scientific value. However, the phylogeny of Cobitinae fishes within genera or family level remains complex and controversial. Up to now, about 60 Cobitinae mitogenomes had been deposited in GenBank, but their i...

journal_title：BMC genomics

authors： Yu P,Zhou L,Yang WT,Miao LJ,Li Z,Zhang XJ,Wang Y,Gui JF

更新日期：2021-01-14 00:00:00

abstract：BACKGROUND:Detoxification in the liver involves activation of nuclear receptors, such as the constitutive androstane receptor (CAR), which regulate downstream genes of xenobiotic metabolism. Frequently, the metabolism of endobiotics is also modulated, resulting in potentially harmful effects. We therefore used 1,4-Bis ...

journal_title：BMC genomics

authors： Rezen T,Tamasi V,Lövgren-Sandblom A,Björkhem I,Meyer UA,Rozman D

更新日期：2009-08-19 00:00:00

abstract：BACKGROUND:Meta-analysis of QTLs combines the results of several QTL detection studies and provides narrow confidence intervals for meta-QTLs, permitting easier positional candidate gene identification. It is usually applied to multiple mapping populations, but can be applied to one. Here, a meta-analysis of drought re...

journal_title：BMC genomics

authors： Khowaja FS,Norton GJ,Courtois B,Price AH

更新日期：2009-06-22 00:00:00

abstract：BACKGROUND:Glycine max is an economically important crop and many different varieties of soybean exist around the world. The first draft sequences and gene models of G. max (domesticated soybean) as well as G. soja (wild soybean), both became available in 2010. This opened the door for comprehensive comparative genomic...

journal_title：BMC genomics

authors： Joshi T,Valliyodan B,Wu JH,Lee SH,Xu D,Nguyen HT

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Human induced pluripotent stem cells (iPSCs) have a wide range of applications throughout the fields of basic research, disease modeling and drug screening. Epigenetic instable iPSCs with aberrant DNA methylation may divide and differentiate into cancer cells. Unfortunately, little effort has been taken to c...

journal_title：BMC genomics

authors： Shao X,Zhang C,Sun MA,Lu X,Xie H

更新日期：2014-11-18 00:00:00

abstract：BACKGROUND:A-to-I RNA editing is a co-/post-transcriptional modification catalyzed by ADAR enzymes, that deaminates Adenosines (A) into Inosines (I). Most of known editing events are located within inverted ALU repeats, but they also occur in coding sequences and may alter the function of encoded proteins. RNA editing ...

journal_title：BMC genomics

authors： Giacopuzzi E,Gennarelli M,Sacco C,Filippini A,Mingardi J,Magri C,Barbon A

更新日期：2018-12-27 00:00:00

abstract：BACKGROUND:Whilst being closely related to the model actinomycete Streptomyces coelicolor A3(2), S. lividans 66 differs from it in several significant and phenotypically observable ways, including antibiotic production. Previous comparative gene hybridization studies investigating such differences have used low-density...

journal_title：BMC genomics

authors： Lewis RA,Laing E,Allenby N,Bucca G,Brenner V,Harrison M,Kierzek AM,Smith CP

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Systems biology and functional genomics require genome-wide datasets and resources. Complete sets of cloned open reading frames (ORFs) have been made for about a dozen bacterial species and allow researchers to express and study complete proteomes in a high-throughput fashion. RESULTS:We have constructed an...

journal_title：BMC genomics

authors： Rajagopala SV,Yamamoto N,Zweifel AE,Nakamichi T,Huang HK,Mendez-Rios JD,Franca-Koh J,Boorgula MP,Fujita K,Suzuki K,Hu JC,Wanner BL,Mori H,Uetz P

更新日期：2010-08-11 00:00:00

abstract：BACKGROUND:It is well understood that distinct communities of bacteria are present at different sites of the body, and that changes in the structure of these communities have strong implications for human health. Yet, challenges remain in understanding the complex interconnections between the bacterial taxa within thes...

journal_title：BMC genomics

authors： Fernandez M,Riveros JD,Campos M,Mathee K,Narasimhan G

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Sugarcane smut is a fungal disease caused by Sporisorium scitamineum. Cultivation of smut-resistant sugarcane varieties is the most effective way to control this disease. The interaction between sugarcane and S. scitamineum is a complex network system. However, to date, there is no report on the identificati...

journal_title：BMC genomics

authors： Su Y,Xiao X,Ling H,Huang N,Liu F,Su W,Zhang Y,Xu L,Muhammad K,Que Y

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:Streptococcus uberis, a Gram positive bacterial pathogen responsible for a significant proportion of bovine mastitis in commercial dairy herds, colonises multiple body sites of the cow including the gut, genital tract and mammary gland. Comparative analysis of the complete genome sequence of S. uberis strain...

journal_title：BMC genomics

authors： Ward PN,Holden MT,Leigh JA,Lennard N,Bignell A,Barron A,Clark L,Quail MA,Woodward J,Barrell BG,Egan SA,Field TR,Maskell D,Kehoe M,Dowson CG,Chanter N,Whatmore AM,Bentley SD,Parkhill J

更新日期：2009-01-28 00:00:00

abstract：BACKGROUND:Distichiasis, an ocular disorder in which aberrant cilia (eyelashes) grow from the opening of the Meibomian glands of the eyelid, has been reported in Friesian horses. These misplaced cilia can cause discomfort, chronic keratitis, and corneal ulceration, potentially impacting vision due to corneal fibrosis, ...

journal_title：BMC genomics

authors： Hisey EA,Hermans H,Lounsberry ZT,Avila F,Grahn RA,Knickelbein KE,Duward-Akhurst SA,McCue ME,Kalbfleisch TS,Lassaline ME,Back W,Bellone RR

更新日期：2020-11-30 00:00:00

abstract：BACKGROUND:Phanerochaete chrysosporium, the model white rot basidiomycetous fungus, has the extraordinary ability to mineralize (to CO2) lignin and detoxify a variety of chemical pollutants. Its cytochrome P450 monooxygenases have recently been implied in several of these biotransformations. Our initial P450 cloning ef...

journal_title：BMC genomics

authors： Doddapaneni H,Chakraborty R,Yadav JS

更新日期：2005-06-14 00:00:00

abstract：BACKGROUND:New gene emergence is so far assumed to be mostly driven by duplication and divergence of existing genes. The possibility that entirely new genes could emerge out of the non-coding genomic background was long thought to be almost negligible. With the increasing availability of fully sequenced genomes across ...

journal_title：BMC genomics

authors： Neme R,Tautz D

更新日期：2013-02-21 00:00:00

abstract：BACKGROUND:ATAC-seq (Assays for Transposase-Accessible Chromatin using sequencing) is a recently developed technique for genome-wide analysis of chromatin accessibility. Compared to earlier methods for assaying chromatin accessibility, ATAC-seq is faster and easier to perform, does not require cross-linking, has higher...

journal_title：BMC genomics

authors： Ou J,Liu H,Yu J,Kelliher MA,Castilla LH,Lawson ND,Zhu LJ

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Siraitia grosvenorii (Luohanguo) is an herbaceous perennial plant native to southern China and most prevalent in Guilin city. Its fruit contains a sweet, fleshy, edible pulp that is widely used in traditional Chinese medicine. The major bioactive constituents in the fruit extract are the cucurbitane-type tri...

journal_title：BMC genomics

authors： Tang Q,Ma X,Mo C,Wilson IW,Song C,Zhao H,Yang Y,Fu W,Qiu D

更新日期：2011-07-05 00:00:00

abstract：BACKGROUND:Microarray technology is limited to monitoring the expression of previously annotated genes that have corresponding probes on the array. Computationally annotated genes have not fully been validated, because ESTs and full-length cDNAs cannot cover entire transcribed regions. Here, mRNA-Seq (an Illumina cDNA ...

journal_title：BMC genomics

authors： Mizuno H,Kawahara Y,Sakai H,Kanamori H,Wakimoto H,Yamagata H,Oono Y,Wu J,Ikawa H,Itoh T,Matsumoto T

更新日期：2010-12-02 00:00:00

abstract：BACKGROUND:Housekeeping (HK) genes are ubiquitously expressed in all tissue/cell types and constitute a basal transcriptome for the maintenance of basic cellular functions. Partitioning transcriptomes into HK and tissue-specific (TS) genes relatively is fundamental for studying gene expression and cellular differentiat...

journal_title：BMC genomics

authors： Zhu J,He F,Song S,Wang J,Yu J

更新日期：2008-04-16 00:00:00

abstract：BACKGROUND:Flow cytometry has been widely used for the diagnosis of various hematopoietic diseases. Although there have been advances in the number of biomarkers that can be analyzed simultaneously and technologies that enable fast performance, the diagnostic data are still interpreted by a manual gating strategy. The ...

journal_title：BMC genomics

authors： Shih MC,Huang SH,Donohue R,Chang CC,Zu Y

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Non-coding small RNAs play critical roles in various cellular processes in a wide spectrum of eukaryotic organisms. Their responses to abiotic stress have become a popular topic of economic and scientific importance in biological research. Several studies in recent years have reported a small number of non-c...

journal_title：BMC genomics

authors： Wang L,Yu X,Wang H,Lu YZ,de Ruiter M,Prins M,He YK

更新日期：2011-06-03 00:00:00

abstract：BACKGROUND:Babesia bovis is an apicomplexan parasite that causes babesiosis in infected cattle. Genomes of pathogens contain promising information that can facilitate the development of methods for controlling infections. Although the genome of B. bovis is publically available, annotated gene models are not highly reli...

journal_title：BMC genomics

authors： Yamagishi J,Wakaguri H,Yokoyama N,Yamashita R,Suzuki Y,Xuan X,Igarashi I

更新日期：2014-08-13 00:00:00

abstract：BACKGROUND:One of the most important global pathogens infecting all age groups is Streptococcus pneumoniae (the 'pneumococcus'). Pneumococci reside in the paediatric nasopharynx, where they compete for space and resources, and one competition strategy is to produce a bacteriocin (antimicrobial peptide or protein) to at...

journal_title：BMC genomics

authors： Bogaardt C,van Tonder AJ,Brueggemann AB

更新日期：2015-07-28 00:00:00

abstract：BACKGROUND:Gene knockouts are a critical resource for functional genomics. In Arabidopsis, comprehensive knockout collections were generated by amplifying and sequencing genomic DNA flanking insertion mutants. These Flanking Sequence Tags (FSTs) map each mutant to a specific locus within the genome. In maize, FSTs have...

journal_title：BMC genomics

authors： Settles AM,Holding DR,Tan BC,Latshaw SP,Liu J,Suzuki M,Li L,O'Brien BA,Fajardo DS,Wroclawska E,Tseung CW,Lai J,Hunter CT 3rd,Avigne WT,Baier J,Messing J,Hannah LC,Koch KE,Becraft PW,Larkins BA,McCarty DR

更新日期：2007-05-09 00:00:00

abstract：BACKGROUND:Copy number variations (CNVs) are a major form of genetic variations and are involved in animal domestication and genetic adaptation to local environments. We investigated CNVs in the domestic goat (Capra hircus) using Illumina short-read sequencing data, by comparing our lab data for 38 goats from three Chi...

journal_title：BMC genomics

authors： Guo J,Zhong J,Liu GE,Yang L,Li L,Chen G,Song T,Zhang H

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:In many eukaryotes, microRNAs (miRNAs) bind to complementary sites in the 3'-untranslated regions (3'-UTRs) of target messenger RNAs (mRNAs) and regulate their expression at the stage of translation. Recent studies have revealed that many miRNAs are evolutionarily conserved; however, the evolution of their t...

journal_title：BMC genomics

authors： Takane K,Fujishima K,Watanabe Y,Sato A,Saito N,Tomita M,Kanai A

更新日期：2010-02-09 00:00:00

abstract：BACKGROUND:Panax notoginseng (Burk) F.H. Chen is important medicinal plant of the Araliacease family. Triterpene saponins are the bioactive constituents in P. notoginseng. However, available genomic information regarding this plant is limited. Moreover, details of triterpene saponin biosynthesis in the Panax species ar...

journal_title：BMC genomics

authors： Luo H,Sun C,Sun Y,Wu Q,Li Y,Song J,Niu Y,Cheng X,Xu H,Li C,Liu J,Steinmetz A,Chen S

更新日期：2011-12-23 00:00:00

abstract：BACKGROUND:Adaptive divergence driven by environmental heterogeneity has long been a fascinating topic in ecology and evolutionary biology. The study of the genetic basis of adaptive divergence has, however, been greatly hampered by a lack of genomic information. The recent development of transcriptome sequencing provi...

journal_title：BMC genomics

authors： Chu JH,Lin RC,Yeh CF,Hsu YC,Li SH

更新日期：2012-04-24 00:00:00

abstract：BACKGROUND:The neonatal bovine mammary fat pad (MFP) surrounding the mammary parenchyma (PAR) is thought to exert proliferative effects on the PAR through secretion of local modulators of growth induced by systemic hormones. We used bioinformatics to characterize transcriptomics differences between PAR and MFP from app...

journal_title：BMC genomics

authors： Piantoni P,Bionaz M,Graugnard DE,Daniels KM,Everts RE,Rodriguez-Zas SL,Lewin HA,Hurley HL,Akers M,Loor JJ

更新日期：2010-05-26 00:00:00