Average probability that a "cold hit" in a DNA database search results in an erroneous attribution.

Abstract:

:We consider a hypothetical series of cases in which the DNA profile of a crime-scene sample is found to match a known profile in a DNA database (i.e., a "cold hit"), resulting in the identification of a suspect based only on genetic evidence. We show that the average probability that there is another person in the population whose profile matches the crime-scene sample but who is not in the database is approximately 2(N - d)p(A), where N is the number of individuals in the population, d is the number of profiles in the database, and p(A) is the average match probability (AMP) for the population. The AMP is estimated by computing the average of the probabilities that two individuals in the population have the same profile. We show further that if a priori each individual in the population is equally likely to have left the crime-scene sample, then the average probability that the database search attributes the crime-scene sample to a wrong person is (N - d)p(A).

journal_name

J Forensic Sci

authors

Song YS,Patil A,Murphy EE,Slatkin M

doi

10.1111/j.1556-4029.2008.00917.x

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

22-7

issue

1

eissn

0022-1198

issn

1556-4029

pii

JFO917

journal_volume

54

pub_type

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