Abstract:
:Volitional swallowing in humans involves the coordination of both brainstem and cerebral swallowing control regions. Peripheral sensory inputs are necessary for safe and efficient swallowing, and their importance to the patterned components of swallowing has been demonstrated. However, the role of sensory inputs to the cerebral system during volitional swallowing is less clear. We used four conditions applied during functional magnetic resonance imaging to differentiate between sensory, motor planning, and motor execution components for cerebral control of swallowing. Oral air pulse stimulation was used to examine the effect of sensory input, covert swallowing was used to engage motor planning for swallowing, and overt swallowing was used to activate the volitional swallowing system. Breath-holding was also included to determine whether its effects could account for the activation seen during overt swallowing. Oral air pulse stimulation, covert swallowing and overt swallowing all produced activation in the primary motor cortex, cingulate cortex, putamen and insula. Additional regions of the swallowing cerebral system that were activated by the oral air pulse stimulation condition included the primary and secondary somatosensory cortex and thalamus. Although air pulse stimulation was on the right side only, bilateral cerebral activation occurred. On the other hand, covert swallowing minimally activated sensory regions, but did activate the supplementary motor area and other motor regions. Breath-holding did not account for the activation during overt swallowing. The effectiveness of oral-sensory stimulation for engaging both sensory and motor components of the cerebral swallowing system demonstrates the importance of sensory input in cerebral swallowing control.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Lowell SY,Poletto CJ,Knorr-Chung BR,Reynolds RC,Simonyan K,Ludlow CLdoi
10.1016/j.neuroimage.2008.04.234subject
Has Abstractpub_date
2008-08-01 00:00:00pages
285-95issue
1eissn
1053-8119issn
1095-9572pii
S1053-8119(08)00517-Xjournal_volume
42pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract::The FN400 refers to the early midfrontally-distributed difference between ERPs elicited by old and new items, which operates in a way consistent with a neural marker of familiarity-based recognition. Double dissociations between the FN400 and a later ERP index of recollection provide some of the most compelling eviden...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.07.047
更新日期:2012-11-15 00:00:00
abstract:BACKGROUND:Neighborhood deprivation adversely effects neurodevelopment and cognitive function; however, mechanisms remain unexplored. Neighborhood deprivation could be particularly impactful in late childhood/early adolescence, in neural regions with protracted developmental trajectories, e.g., prefrontal cortex (PFC)....
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.117086
更新日期:2020-10-15 00:00:00
abstract::Some cross-sectional studies suggest reduced cerebellar volumes with aging, but there have been few longitudinal studies of age changes in cerebellar subregions in cognitively healthy older adults. In this work, 2,023 magnetic resonance (MR) images of 822 cognitively normal participants from the Baltimore Longitudinal...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.117062
更新日期:2020-10-15 00:00:00
abstract::One of the most remarkable disorders following brain damage is prosopagnosia, the inability to recognize faces. While a number of cases of prosopagnosia have been described at the behavioral level, the functional neuroanatomy of this face recognition impairment, and thus the brain regions critically involved in normal...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.09.051
更新日期:2007-04-01 00:00:00
abstract::Connectome mapping using techniques such as functional magnetic resonance imaging (fMRI) has become a focus of systems neuroscience. There remain many statistical challenges in analysis of functional connectivity and network architecture from BOLD fMRI multivariate time series. One key statistic for any time series is...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.04.052
更新日期:2016-11-15 00:00:00
abstract::A series of reports have recently appeared using tensor based morphometry statistically-defined regions of interest, Stat-ROIs, to quantify longitudinal atrophy in structural MRIs from the Alzheimer's Disease Neuroimaging Initiative (ADNI). This commentary focuses on one of these reports, Hua et al. (2010), but the is...
journal_title:NeuroImage
pub_type: 评论,杂志文章
doi:10.1016/j.neuroimage.2010.11.092
更新日期:2011-07-01 00:00:00
abstract::Although, on average, the magnitude of alpha oscillations (8 to 12 Hz) is decreased in task-relevant cortices during externally oriented attention, its fluctuations have significant consequences, with increased level of alpha associated with decreased level of visual processing and poorer behavioral performance. Funct...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.11.058
更新日期:2013-03-01 00:00:00
abstract::We introduce an automatic method that we call tract-based morphometry, or TBM, for measurement and analysis of diffusion MRI data along white matter fiber tracts. Using subject-specific tractography bundle segmentations, we generate an arc length parameterization of the bundle with point correspondences across all fib...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.12.023
更新日期:2009-04-15 00:00:00
abstract::Friston et al. (1995, NeuroImage 2:45-53) presented a method for detecting activations in fMRI time-series based on the general linear model and a heuristic analysis of the effective degrees of freedom. In this communication we present corrected results that replace those of the previous paper and solve the same probl...
journal_title:NeuroImage
pub_type: 评论,杂志文章
doi:10.1006/nimg.1995.1023
更新日期:1995-09-01 00:00:00
abstract::Diffusion-weighted images of the human brain are acquired more and more routinely in clinical research settings, yet segmenting and labeling white matter tracts in these images is still challenging. We present in this paper a fully automated method to extract many anatomical tracts at once on diffusion tensor images, ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.06.020
更新日期:2011-09-15 00:00:00
abstract::Brain morphology varies during the course of the menstrual cycle, with increases in individual gray matter volume at the time of ovulation. This study implemented our previously presented BrainAGE framework to analyze short-term neuroanatomical changes in healthy young women due to hormonal changes during the menstrua...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.04.036
更新日期:2015-07-15 00:00:00
abstract::The primary gustatory area is located in the insular cortex. Although the insular cortex has been the topic of multiple parcellation studies, its functional specialization regarding taste processing received relatively little attention. Studies investigating the brain response to taste suggested that the insular corte...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.06.062
更新日期:2015-10-01 00:00:00
abstract::Simultaneous recording of brain activity by different neurophysiological modalities can yield insights that reach beyond those obtained by each technique individually, even when compared to those from the post-hoc integration of results from each technique recorded sequentially. Success in the endeavour of real-time m...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2007.11.039
更新日期:2008-04-01 00:00:00
abstract::The serotonergic system is one of the major systems targeted in the pharmacological treatment of a wide range of mood disorders including depression; however, little is known about the neurophysiological mechanisms underlying the effects of serotonin (5-HT) on affective phenomena including emotional behaviours, mood a...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.neuroimage.2004.03.022
更新日期:2004-07-01 00:00:00
abstract::When we decide between two options, we can make our decision based on what we prefer, (preference-based choice), or we can also choose based on which option we want to avoid more (non-preference-based choice). Most decision making research has examined preference-based choice but has not differentiated it from non-pre...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.03.046
更新日期:2014-07-15 00:00:00
abstract::Brain imaging studies have suggested a critical role for prefrontal cortex in working memory (WM) tasks that require both maintainenance and manipulation of information over time in delayed-response WM tasks. In the present study, functional magnetic resonance imaging (fMRI) was used to examine whether prefrontal area...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1998.0404
更新日期:1999-02-01 00:00:00
abstract::Accurate estimation of location and extent of neuronal sources from EEG/MEG remain challenging. In the present study, a new source imaging method, i.e. variation and wavelet based sparse source imaging (VW-SSI), is proposed to better estimate cortical source locations and extents. VW-SSI utilizes the L1-norm regulariz...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.09.070
更新日期:2014-02-01 00:00:00
abstract::The role of primary visual cortex (V1) in encoding physical stimulus features is well known, while stimulus categorization is mainly attributed to higher visual areas. However, visual experience is not stripped down to invariant, categorical-only "labels." Rather, visual experiences are remarkably rich with details re...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.10.072
更新日期:2016-01-15 00:00:00
abstract::Developments in imaging technology have made three-dimensional visualization of internal brain structures possible with excellent resolution. Since improved visualization implies improved measurement, these advances hold promise to more accurately measure the volumes of internal structures. As new technologies and tec...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1994.1004
更新日期:1994-06-01 00:00:00
abstract::This paper describes an investigation of gangliocytes via imaging semithin sections of two human trigeminal ganglia with an atomic force microscope (AFM). Whereas semithin sections are usually employed for transmission electron microscopy, we adopted this special type of sample preparation for our AFM studies to extra...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2001.0924
更新日期:2001-12-01 00:00:00
abstract::Orientation selectivity is a fundamental property of neurons in the visual cortex for form perception. Cortical cells with similar preferred orientations are organized in a columnar manner to form a two-dimensional orientation map in the primary visual cortex (area 17). There are several mechanisms underlying the gene...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.12.014
更新日期:2008-04-01 00:00:00
abstract::Recent research has shown an increased rate of conversion to dementia in subjects with mild cognitive impairment (MCI) compared to controls. However, there are no specific methods to predict who will later develop dementia. In the present study, 22 controls and 56 MCI subjects were followed on average for 37 months (m...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.06.016
更新日期:2007-10-01 00:00:00
abstract::In this work we report findings from an in vivo diffusion tensor imaging (DTI) study of the human optic chiasm at sub-millimeter voxel resolution. Data were collected at 3 T using a diffusion-weighted radial-FSE sequence, which provides images free from typical magnetic susceptibility artifacts. The general DTI featur...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.05.098
更新日期:2009-10-01 00:00:00
abstract::Correction for multiple comparisons in neuroimaging data is an important area of research. Recently, wavelet-based methods have gained popularity and have been reported to achieve better sensitivity compared to spatial domain methods. However, these techniques produce smoothed statistical maps which are difficult to i...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1016/j.neuroimage.2006.06.033
更新日期:2006-10-15 00:00:00
abstract::Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a wide phenotypic range, often affecting personality and communication. Previous voxel-based morphometry (VBM) studies of ASD have identified both gray- and white-matter volume changes. However, the cerebral cortex is a 2-D sheet with a highly folded...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.12.047
更新日期:2010-04-01 00:00:00
abstract::PET scanners devoted to in vivo functional study have recently been developed, but autoradiography remains the reference technique for assessing cerebral glucose metabolism (CMRGlu) in rodents. Autoradiographs are conventionally subjected to region of interest (ROI) analysis, which is intrinsically hypothesis-driven a...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.11.054
更新日期:2008-04-01 00:00:00
abstract:RATIONAL:The human perirhinal cortex (PRC) plays critical roles in episodic and semantic memory and visual perception. The PRC consists of Brodmann areas 35 and 36 (BA35, BA36). In Alzheimer's disease (AD), BA35 is the first cortical site affected by neurofibrillary tangle pathology, which is closely linked to neural i...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.09.070
更新日期:2017-01-01 00:00:00
abstract::Theta-burst stimulation (TBS), a novel repetitive transcranial magnetic stimulation (TMS) protocol, is capable of suppressing the amplitude of contralateral motor-evoked potentials (MEP) for several minutes after the end of a conditioning train over the motor cortex. It remains unknown whether TBS leads to effects on ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2007.11.037
更新日期:2008-03-01 00:00:00
abstract::In this work, we investigated the use of real-time functional magnetic resonance imaging (fMRI) with neurofeedback training (NFT) to teach volitional down-regulation of the auditory cortex (AC) using directed attention strategies as there is a growing interest in the application of fMRI-NFT to treat neurologic disorde...
journal_title:NeuroImage
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.neuroimage.2019.03.078
更新日期:2019-07-15 00:00:00
abstract::We determined if high-frequency gamma-oscillations (50- to 150-Hz) were induced by simple auditory communication over the language network areas in children with focal epilepsy. Four children (aged 7, 9, 10 and 16 years) with intractable left-hemispheric focal epilepsy underwent extraoperative electrocorticography (EC...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2008.03.011
更新日期:2008-07-01 00:00:00