Abstract:
:This paper describes an investigation of gangliocytes via imaging semithin sections of two human trigeminal ganglia with an atomic force microscope (AFM). Whereas semithin sections are usually employed for transmission electron microscopy, we adopted this special type of sample preparation for our AFM studies to extract topographical data from the gangliocyte itself and from the nucleus, the nucleolus, the crystal-arranged lipofuscin granules, and the cell-surrounding mantle cells; simultaneously we characterized the samples with error signal mode. This AFM-related technique revealed no information concerning friction force and elasticity due to the presence of the embedding material (epoxy), but it gave additional topographical contrast. These are the first images of the human trigeminal ganglion by AFM.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Melling M,Hochmeister S,Blumer R,Schilcher K,Mostler S,Behnam M,Wilde J,Karimian-Teherani Ddoi
10.1006/nimg.2001.0924keywords:
subject
Has Abstractpub_date
2001-12-01 00:00:00pages
1348-52issue
6eissn
1053-8119issn
1095-9572pii
S1053-8119(01)90924-3journal_volume
14pub_type
杂志文章相关文献
NEUROIMAGE文献大全abstract::Stress resilience is mediated, in part, by our ability to predict and control threats within our environment. Therefore, determining the neural mechanisms that regulate the emotional response to predictable and controllable threats may provide important new insight into the processes that mediate resilience to emotion...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.06.086
更新日期:2015-10-01 00:00:00
abstract::Allocation of attentional resources to portions of the available sensory input can be regulated by bottom-up processes, i.e., spontaneous orientation towards an oncoming stimulus (stimulus-driven attention), and by top-down processes, i.e., intentionally and driven by knowledge, expectation and goals. The present stud...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.04.177
更新日期:2006-08-15 00:00:00
abstract::Motion artifacts are a significant source of noise in many functional near-infrared spectroscopy (fNIRS) experiments. Despite this, there is no well-established method for their removal. Instead, functional trials of fNIRS data containing a motion artifact are often rejected completely. However, in most experimental c...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2013.04.082
更新日期:2014-01-15 00:00:00
abstract::Various neuroimaging measures are being evaluated for tracking Alzheimer's disease (AD) progression in therapeutic trials, including measures of structural brain change based on repeated scanning of patients with magnetic resonance imaging (MRI). Methods to compute brain change must be robust to scan quality. Biases m...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2012.10.086
更新日期:2013-02-01 00:00:00
abstract::Recent animal studies have suggested that cortical areas may play a greater role in the modulation of abnormal oscillatory activity in Parkinson's disease (PD) than previously recognized. We investigated task and medication-dependent, EEG-based directional cortical connectivity in the θ (4-7Hz), α (8-12Hz), β (13-30Hz...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2011.03.018
更新日期:2011-06-15 00:00:00
abstract::The underlying mechanism of how the human brain solves the cocktail party problem is largely unknown. Recent neuroimaging studies, however, suggest salient temporal correlations between the auditory neural response and the attended auditory object. Using magnetoencephalography (MEG) recordings of the neural responses ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.09.048
更新日期:2016-01-01 00:00:00
abstract::The brain's energy economy excessively favors intrinsic, spontaneous neural activity over extrinsic, evoked activity, presumably to maintain its internal organization. Emerging hypotheses capable of explaining such an investment posit that the brain's intrinsic functional architecture encodes a blueprint for its reper...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.10.046
更新日期:2011-02-14 00:00:00
abstract::Multi-voxel pattern analysis (MVPA) has led to major changes in how fMRI data are analyzed and interpreted. Many studies now report both MVPA results and results from standard univariate voxel-wise analysis, often with the goal of drawing different conclusions from each. Because MVPA results can be sensitive to latent...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.04.037
更新日期:2014-08-15 00:00:00
abstract::A concern for researchers planning multisite studies is that scanner and T1-weighted sequence-related biases on regional volumes could overshadow true effects, especially for studies with a heterogeneous set of scanners and sequences. Current approaches attempt to harmonize data by standardizing hardware, pulse sequen...
journal_title:NeuroImage
pub_type: 杂志文章,多中心研究
doi:10.1016/j.neuroimage.2016.03.051
更新日期:2016-07-01 00:00:00
abstract::To better understand the mechanisms by which working memory training can augment human performance we continuously monitored trainees with near infrared spectroscopy (NIRS) while they performed a dual verbal-spatial working memory task. Linear mixed effects models were used to model the changes in cerebral hemodynamic...
journal_title:NeuroImage
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.neuroimage.2013.05.103
更新日期:2014-01-15 00:00:00
abstract::Magnetization transfer contrast has yielded insight into brain tissue microstructure changes across the lifespan and in a range of disorders. This progress has been aided by the development of quantitative magnetization transfer imaging techniques able to extract intrinsic properties of the tissue that are independent...
journal_title:NeuroImage
pub_type: 杂志文章,评审
doi:10.1016/j.neuroimage.2017.11.065
更新日期:2018-11-15 00:00:00
abstract::Modeling the relationships among brain regions of interest (ROIs) carries unique potential to explicate how the brain orchestrates information processing. However, hurdles arise when using functional MRI data. Variation in ROI activity contains sequential dependencies and shared influences on synchronized activation. ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2009.12.117
更新日期:2010-04-15 00:00:00
abstract::Transient intrinsic optical responses associated with neural activation offer an attractive strategy for dynamic imaging of neural activity, and may provide a noninvasive methodology for imaging of retinal function. Here we demonstrate the feasibility of near infrared imaging of fast intrinsic optical changes in isola...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2006.06.060
更新日期:2006-11-15 00:00:00
abstract::A new method is presented to map the orientation of intravoxel crossing fibers by using the phase of the diffusion circular spectrum harmonics. In a previous study [Zhan, W., Gu, H., Xu, S., Silbersweig, D.A., Stern, E., Yang, Y., 2003. Circular spectrum mapping for intravoxel fiber structures based on high angular re...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2004.07.062
更新日期:2004-12-01 00:00:00
abstract::We describe a mathematical model linking changes in cerebral blood flow, blood volume and the blood oxygenation state in response to stimulation. The model has three compartments to take into account the fact that the cerebral blood flow and volume as measured concurrently using laser Doppler flowmetry and optical ima...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2005.06.042
更新日期:2005-12-01 00:00:00
abstract::The analysis of auditory deviant events outside the focus of attention is a fundamental capacity of human information processing and has been studied in experiments on Mismatch Negativity (MMN) and the P3a component in evoked potential research. However, generators contributing to these components are still under disc...
journal_title:NeuroImage
pub_type: 临床试验,杂志文章
doi:10.1006/nimg.2002.1176
更新日期:2002-09-01 00:00:00
abstract::When studying complex cognitive tasks using functional magnetic resonance imaging (fMRI) one often encounters weak signal responses. These weak responses are corrupted by noise and artifacts of various sources. Preprocessing of the raw data before the application of test statistics helps to extract the signal and can ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.1999.0490
更新日期:1999-11-01 00:00:00
abstract::Non-invasive imaging has the potential to play a crucial role in the characterization and translation of experimental animal models to investigate human brain development and disorders, especially when employed to study animal models that more accurately represent features of human neuroanatomy. The purpose of this st...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2017.03.009
更新日期:2017-05-15 00:00:00
abstract::EEG mu rhythms (8-13 Hz) recorded at fronto-central electrodes are generally considered as markers of motor cortical activity in humans, because they are modulated when participants perform an action, when they observe another's action or even when they imagine performing an action. In this study, we analyzed the time...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.01.018
更新日期:2015-04-01 00:00:00
abstract::Deep brain stimulation (DBS) of the periaqueductal gray (PAG) is used in the treatment of severe refractory neuropathic pain. We tested the hypothesis that DBS releases endogenous opioids to exert its analgesic effect using [11C]diprenorphine (DPN) positron emission tomography (PET). Patients with de-afferentation pai...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.08.038
更新日期:2017-02-01 00:00:00
abstract::Sleep is an evolutionarily conserved process required for human health and functioning. Insufficient sleep causes impairments across cognitive domains, and sleep deprivation can have rapid antidepressive effects in mood disorders. However, the neurobiological effects of waking and sleep are not well understood. Recent...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2017.05.027
更新日期:2017-08-01 00:00:00
abstract::We report experiments designed to learn whether different kinds of perceptually unstable visual images engage different neural mechanisms. 21 subjects viewed two types of bi-stable images while we scanned the activity in their brains with functional magnetic resonance imaging (fMRI); in one (intra-categorical type) th...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2014.01.040
更新日期:2014-05-01 00:00:00
abstract::Human communication and survival depend on effective social information processing. Abundant behavioral evidence has shown that humans efficiently judge preferences for other individuals, a critical task in social interaction, yet the neural mechanism of this basic social evaluation, remains less than clear. Using a s...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2010.02.044
更新日期:2010-06-01 00:00:00
abstract::The BOLD signal, as the basis of functional MRI, arises from both neuronal and vascular factors, with their respective contributions to resting state-fMRI still unknown. Among the factors contributing to "physiological noise", dynamic arterial CO2 fluctuations constitutes the strongest and the most widespread modulato...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2020.116874
更新日期:2020-08-01 00:00:00
abstract::There is a significant amount of interest in studying the thalamus because of its central location in the brain and its role as a gatekeeper to higher centers of cognition. Imaging and measuring of the individual subnuclei of the thalamus has proven extremely difficult in MR because of the contrast-to-noise (CNR) of t...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1006/nimg.2000.0552
更新日期:2000-04-01 00:00:00
abstract::The human LGN and SC consist of distinct layers, but their layer-specific response properties remain poorly understood. In this fMRI study, we characterized visual response properties of the magnocellular (M) and parvocellular (P) layers of the human LGN, as well as at different depths in the SC. Results show that fMR...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.02.025
更新日期:2015-05-01 00:00:00
abstract::Sensorimotor synchronization (SMS) to an external auditory rhythm is a developed ability in humans, particularly evident in dancing and singing. This ability is typically measured in the lab via a simple task of finger tapping to an auditory beat. While simplistic, there is some evidence that poor performance on this ...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.05.022
更新日期:2016-09-01 00:00:00
abstract::In any non-deterministic environment, unexpected events can indicate true changes in the world (and require behavioural adaptation) or reflect chance occurrence (and must be discounted). Adaptive behaviour requires distinguishing these possibilities. We investigated how humans achieve this by integrating high-level in...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2016.08.057
更新日期:2017-02-01 00:00:00
abstract::Hippocampal volume has been shown to be sensitive to variations in estrogen and progesterone levels across rodents' estrous cycle. However, little is known about the covariation of hormone levels and brain structure in the course of the human menstrual cycle. Here, we examine this covariation with a multi-method appro...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2015.06.012
更新日期:2015-09-01 00:00:00
abstract::Electroencephalographic (EEG) and magnetoencephalographic (MEG) signals can often be exposed to strong power line interference at 50 or 60 Hz. A widely used method to remove line noise is the notch filter, but it comes with the risk of potentially severe signal distortions. Among other approaches, the Discrete Fourier...
journal_title:NeuroImage
pub_type: 杂志文章
doi:10.1016/j.neuroimage.2019.01.026
更新日期:2019-04-01 00:00:00