A whole more than the sum of its synthetic parts.

Abstract:

:Synthetic biology is the realization of systems with desired behavior using biological materials. A recent addition to the field is a bipartite consortium of the bacterium Escherichia coli in which each species harbors complementary gene circuits that actuate only when both are present above a critical density. This bacterial "consensus" system, functional in liquid, solid, and biofilm niches, represents a novel strategy that raises the bar in terms of the specificity and complexity of tasks performed by engineered organisms.

journal_name

ACS Chem Biol

journal_title

ACS chemical biology

authors

Wong JV,Song H,You L

doi

10.1021/cb700256w

subject

Has Abstract

pub_date

2008-01-18 00:00:00

pages

27-9

issue

1

eissn

1554-8929

issn

1554-8937

journal_volume

3

pub_type

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