Abstract：
:The diagnostic accuracy of an investigational test for cervix cancer screening is studied. The method involves a vaginal tampon that changes colour in relation to LDH activity and can detect preinvasive and invasive cervical lesions. The test was applied in 50 women with CIN, 50 women with histologically proved cervical cancer and in 500 women with no history of malignancy. The test was positive in 54% of CINs and 86% of cervix cancer patients, while it was not specific in 16% and 4% respectively. Among 268 healthy controls the test results were negative in 77.99% and false positive in 12.31%. The test can be performed any day of the menstrual cycle apart from the time of menstruation. It can also be performed, without any serious problem of misinterpretation in women suffering from myomas, vaginal relaxation or menstrual disorders. On the contrary, the test should be avoided if vaginitis or cervicitis are present, since false positive conclusions might be drawn. The test results suggest that the sensitivity of this method was 77% and the specificity 86% if we exclude the benign conditions that influence or possibly influence the colour indication of the tampon.
journal_name
Eur J Gynaecol Oncoljournal_title
European journal of gynaecological oncologyauthors
Gerolymatos A,Fotiou S,Tserkezoglou A,Somarakis M,Katsilieris J,Kotsalis N,Aravantinos Dsubject
Has Abstractpub_date
1991-01-01 00:00:00pages
471-6issue
6eissn
0392-2936issn
2709-0086journal_volume
12pub_type
杂志文章abstract：:2195 patients affected by endometrial carcinoma were treated at the Tbilisi and the St. Petersburg Oncological Institutes from 1968 to 1987. The incidence of different stages was respectively: I 78.8%; II 11.6%; III 9.0%; IV 0.4%. Adenocarcinoma was the histotype more frequently observed and the grade of differentiati...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,多中心研究
doi：
更新日期：1993-01-01 00:00:00
abstract：:This study aimed to observe the effects of octreotide (OCT) on cisplatin resistance reversal of cancer cells in vitro and in nude mice in vivo. MTT method and flow cytometry were used to investigate the effect of cisplatin, OCT or the combination of these two compounds on the proliferation and apoptosis of SKOV3-DDP c...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:Infection with high-risk human papillomavirus (hr-HPV) 16, 18, and 45 causes 94% of cervical carcinoma. In the present screening center the authors perform the hr-HPV test followed by Pap test to women aged 35-64 years if they result hr-HPV+. The authors' aimed to provide data regarding the genotyping test and eventua...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2015-01-01 00:00:00
abstract：:The study comprised 71 women from 1st Clinic of Gynecology Medical Academy of Cracow from 30 to 76 years (means = 52.5) with VIN and early invasive cancer of the vulva. The clinical examination, colposcopy, cytology, histology of target biopsy and culture of microorganisms taken from the vulva were performed in all ca...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:We present a case of a 30-year-old pregnant woman in whom an ovarian mass was identified by ultrasonography at 15 weeks' gestation. A markedly elevated maternal serum alphafetoprotein (MSAFP) suggested a diagnosis of endodermal sinus tumour of the ovary. A right salpingo-oophorectomy at 19 weeks' gestation enabled his...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:Endometrial adenocarcinoma is the most common malignant neoplasm of the female genital tract and, despite its relative frequency, the molecular events that contribute to the development and progression of the lesion remain poorly understood. The normal human endometrium is characterized by hormone-dependent variations...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2005-01-01 00:00:00
abstract：:The influence of various CO2 laser surgical techniques on tumor behaviour was examined in an experimental model on C56BL/6 mice (n = 106) with Lewis Lung carcinomas and compared with that of scalpel excised tumors. Comparisons were made between the healing procedure, the local recurrence rate, metastatic behaviour and...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Malignant mixed müllerian tumors are very rare neoplasms of the fallopian tube, and treatment is not well defined. A case of malignant mixed müllerian tumor of the tube concomitant with a primary serous carcinoma of the ovary is reported. It was unclear if there were two distinct neoplasms in the same patient, or if i...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To determine if there are founder BRCA1 mutations in the Mongolian population. METHODS:Seventeen women with ovarian cancer, 14 women with premenopausal breast cancer and one woman with both cancer types were interviewed to obtain family history, and hormonal, reproductive and environment risk factor informat...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:From 1978 to 1985 a total of 151 patients were treated for endometrial carcinoma. Of these, 25 patients underwent extrafascial abdominal hysterectomy and pelvic lymphadenectomy, 25 were treated according to Wertheim procedure and pelvic lymphadenectomy and 32 underwent intrafascial abdominal hysterectomy; 62 women und...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:In the under-resourced world, transfusion to advanced oncological patients involves two major problems, i.e., (a) transfusion transmitted disease, and (b) infrastructural deficiency. Many hospitals cannot cope with the specialized requirements of immunocompromised cancer victims, for instance, leucoreduction, selectiv...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to investigate whether the partition-defective 3 protein (Par3) regulates cervical carcinoma growth and metastasis. MATERIALS AND METHODS:Immunohistochemistry (IHC) was used to analyze the expression of Par3 protein in samples from 89 cervical squamous cell carcinoma (CSCC) patient...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2017-01-01 00:00:00
abstract：PURPOSE:Intra-abdominal adhesions are a major complication of healing. Furthermore these adhesions may cause morbidity and sometimes mortality for patients, and also are a financial burden to the health system. MATERIALS AND METHODS:Cecum abrasion was performed in all rats and solutions containing saline to group 1, 5...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：:Treatment of Stage IB-IIA cervical carcinoma is controversial. The choice to perform surgery or chemoradiation depends on the FIGO Stage, which does not include evaluation of lymph node involvement, although the prognosis of the patients depends on this evaluation. There is no method however, to safely evaluate preope...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are very rare uterine neoplasms. They mostly behave in a benign fashion but cases were reported with extra-uterine spread. There are less than 50 cases reported in the literature so far according to the present authors' knowledge. We report a case of 45-year...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：:402 radical hysterectomies (17 ultraradical) were performed with lymphadenectomy. Positive metastatic nodes (N+) rate was 23.6% with an arithmetic mean of 22 excised lymph nodes. Single N+ belonged mostly to the obturatory group, double N+ to obturatory and external iliac groups, while multiple N+ (24 cases) had no pa...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：OBJECTIVE:To explore the outcomes of oncology, fertility, and pregnancy in patients after undergoing neoadjuvant chemotherapy (NACT) followed by fertility-sparing operations with cervical cancer, and its value in clinical treatment. MATERIALS AND METHODS:A total of 11 patients from seven hospitals in Beijing with cerv...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2016-01-01 00:00:00
abstract：:A 35-year-old woman presented with an adnexal mass which came out as a leiomyosarcoma of the broad ligament arising in a pre-existing pure neurilemmoma-like leiomyoma. This is the first reported case of leiomyosarcoma arising in a pure neurilemmoma-like leiomyoma, the third reported case at an unusually young age show...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:The objective of this study is to describe a new technique of laparoscopic radical hysterectomy without vaginal cuff closure. METHODS:Three patients underwent laparoscopic radical hysterectomy, bilateral salpingo-oophorectomy and bilateral pelvic lymph node dissection using an Argon Beam Coagulator. Four tro...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:Bacterial vaginosis (BV) is a condition that seldom occurs in prepuberal girls or postmenopausal women, suggesting a hormonal component in its aetiology. The precise mechanisms by which BV arises are not fully understood. One proposed mechanism suggests that carcinogenic nitrosamines act either independently or via hu...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:Optimal cytoreduction is a major prognostic factor in ovarian cancer; several clinical, radiological and biochemical predictors have been studied. Tumour M2-PK (TU M2-PK) is over-expressed in tumour cells and can be detected in plasma samples but its role in ovarian cancer has not yet been evaluated. OBJECT...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:The objective was to improve the design of the indwelling-intrauterine tube (IIUT) for brachy-radiotherapy of cervical cancer or sleeve, specifically one that would not require stitching to retain it properly in the uterus for periods of one to two weeks and to ensure hygiene by making them disposable, thinne...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:A case of microcarcinoma of the vulva (depth of invasion less than 5 mm) with an unexpected natural history is reported. The 338 cases, up today, reported in literature are reviewed and therapeutical protocols discussed. ...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：PURPOSE:The value of neoadjuvant chemotherapy in squamous cell carcinomas of the cervix has not been proven. It has been suggested that the potential benefit of this therapy on local and occult metastatic disease could be offset by delaying effective radiation therapy and selection of more aggressive tumor clones. This...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:Within the context of a prospective study we investigated the influence of malignant and benign breast disease on the coagulation systems both prior to and after surgery. In addition we also investigated to what extent individual risk factors aid the formation of a thrombophiliac risk profile. Altogether 50 patients w...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：INTRODUCTION:Methylation of genomic DNA is one of the major mechanisms that deactivates genes and regulates their tissue-specific transcription levels. Its patterns are based on clonal inheritance that occurs in the early stages of embryogenesis. All changes in the DNA methylation levels occurring especially in the pro...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：PURPOSE OF INVESTIGATION:Cervical cancer is the second most common malignancy in women, in both incidence and mortality. In the present study, we report our results of treating 93 consecutive patients with early invasive cervical cancers (Stages I-IIA). METHODS:The patients of this study comprised all women recognized...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:Most of the cases showing good prognosis in literature are probably intermediate tumors between benign and malignant of undetermined malignant potential (UMP) and other tumors with intermediate features which are currently not considered among sarcomas. Misdiagnosis of a malignant lesion as a benign one has a tragic o...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章,评审
doi：
更新日期：2013-01-01 00:00:00
abstract：:We report the case of an unsuspected G.I. cancer in a patient with no clinical signs other than ascites and positive PAP-smear on admission. Histologically, neither endometrium nor cervix were involved. To date, only 2 cases of primary gastrointestinal (gastric) cancers with no metastases to the cervix, suspected by P...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Ovarian carcinoma is a malignancy with a poor prognosis especially in patients with advanced disease. The majority of patients with ovarian serous carcinoma are diagnosed in advanced stages. Palpable extraabdominal lymphadenopathy at the time of presentation is distinctly uncommon. This case report addresses a patient...
journal_title：European journal of gynaecological oncology
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
