Abstract:
OBJECTIVE:To investigate the relationship between adult male circumcision and sexual satisfaction and function in men, as observational studies on the effect of adult male circumcision on sexual satisfaction show conflicting results. SUBJECTS AND METHODS:We investigated self-reported sexual satisfaction and function among men enrolled in a randomized trial of male circumcision for human immunodeficiency virus (HIV) prevention conducted in Rakai, Uganda. In all, 4456 sexually experienced HIV-negative males aged 15-49 years were enrolled; 2210 were randomized to receive immediate circumcision (intervention arm) and 2246 to circumcision delayed for 24 months (control arm). Men were followed up at 6, 12 and 24 months, and information on sexual desire, satisfaction and erectile dysfunction was collected. These variables were compared between the study arms and over time within the study arms, using chi-square or Fisher's exact tests. The trial registration number is NCT00425984. RESULTS:There were no differences between the study arms at enrollment and problems with sexual satisfaction and function were reported by <2% of participants in both study arms at all time points. At 6 months, no difficulty with penetration was reported by 98.6% of circumcised men and 99.4% of controls (P = 0.02), and no pain on intercourse was reported by 99.4% circumcised and 98.8% of uncircumcised men (P = 0.05). There were no differences between the study arms in penetration or dyspareunia at later visits. Sexual satisfaction increased from 98.0% at enrollment to 99.9% at 2 years among the controls (P < 0.001), but there was no trend in satisfaction among circumcised men (enrollment 98.5%, 2 years 98.4%, P = 0.8). CONCLUSION:Adult male circumcision does not adversely affect sexual satisfaction or clinically significant function in men.
journal_name
BJU Intjournal_title
BJU internationalauthors
Kigozi G,Watya S,Polis CB,Buwembo D,Kiggundu V,Wawer MJ,Serwadda D,Nalugoda F,Kiwanuka N,Bacon MC,Ssempijja V,Makumbi F,Gray RHdoi
10.1111/j.1464-410X.2007.07369.xsubject
Has Abstractpub_date
2008-01-01 00:00:00pages
65-70issue
1eissn
1464-4096issn
1464-410Xpii
BJU7369journal_volume
101pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:To determine the efficacy of fluoroquinolone prophylaxis in patients undergoing transrectal ultrasonography (TRUS)-guided biopsy of the prostate in the Norwich population, and its correlation with ciprofloxacin resistance in the faecal flora. We also aimed to determine the usefulness of a pre-biopsy rectal sc...
journal_title:BJU international
pub_type: 杂志文章
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abstract:OBJECTIVE:To investigate the immunohistochemical expression of topoisomerase II-alpha (TII-alpha, a nuclear enzyme, the expression of which increases rapidly at the end of the S to G2/M phase and declines when mitosis ends) in bladder urothelial neoplasms (transitional cell carcinoma), and its correlation with grade, s...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04118.x
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abstract:OBJECTIVE:To determine the outcome 10 years after an individual course of pelvic floor muscle (PFM) exercises for genuine stress incontinence. PATIENTS AND METHODS:Postal questionnaires were sent to 52 women who had undergone PFM training 10 years earlier, and their medical files were reviewed. The main outcome measur...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00506.x
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abstract:OBJECTIVES:To investigate long-term oncological outcomes after laparoscopic radical prostatectomy (LRP). To identify parameters influencing recurrence-free survival in a single-institution series. PATIENTS AND METHODS:All patients underwent LRP using the transperitoneal retrograde Heilbronn technique. High-risk patien...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2012.11317.x
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abstract:OBJECTIVE:To investigate cell division cycle 91-like 1 (CDC91L1; also called phosphatidylinositol glycan class U, PIG-U) expression in bladder cancer at both the mRNA and protein levels, and to study its clinical and prognostic significance, as CDC91L1 was recently identified as a new oncogene in human bladder cancer a...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2007.07192.x
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To develop and test the safety and feasibility of a novel anti-biofilm mechanism configured for wireless capsule endoscopy (WCE) in a sheep bladder model. MATERIALS AND METHODS:A WCE mechanism, designed for long-term bladder monitoring, was developed and introduced into a sheep bladder for 5 months. The tran...
journal_title:BJU international
pub_type: 杂志文章
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abstract:OBJECTIVE:To determine the outcomes of open ureterolysis in a contemporary cohort of patients presenting with ureteric obstruction secondary to retroperitoneal fibrosis (RPF). PATIENTS AND METHODS:We conducted a prospective analysis of 50 patients undergoing open ureterolysis and omental wrap between January 2012 and ...
journal_title:BJU international
pub_type: 杂志文章
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abstract:OBJECTIVES:To analyse the gene expression level of prostate stem cell antigen (PSCA) in human clear cell renal cell carcinoma (CC-RCC) and its relationship with conventional clinicopathological manifestations, to evaluate its prognostic value for patient outcome, and to determine the effect of PSCA on the progression o...
journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06350.x
更新日期:2006-09-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,多中心研究
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journal_title:BJU international
pub_type: 杂志文章
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journal_title:BJU international
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1464-410X.2011.10371.x
更新日期:2012-01-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2005.05576.x
更新日期:2005-07-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2003.04009.x
更新日期:2003-01-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2011.10193.x
更新日期:2011-05-01 00:00:00
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doi:10.1111/j.1464-410X.2009.08609.x
更新日期:2010-01-01 00:00:00
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journal_title:BJU international
pub_type: 临床试验,杂志文章
doi:10.1046/j.1464-410x.2002.02788.x
更新日期:2002-06-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2001.02268.x
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2004.04861.x
更新日期:2004-06-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章,评审
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更新日期:2001-02-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:BJU international
pub_type: 杂志文章
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更新日期:2005-10-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
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更新日期:2004-08-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2008.07921.x
更新日期:2008-12-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/j.1464-410X.2010.09417.x
更新日期:2010-11-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1046/j.1464-410x.2000.00722.x
更新日期:2000-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1464-410X.2006.06209.x
更新日期:2006-07-01 00:00:00
abstract:UNLABELLED:What's known on the subject? and What does the study add? For the past 30 years Serenoa repens has become a widely used phytotherapy in the USA and in Europe, mostly because of positive comparisons to α-blockers and 5α-reductase inhibitors. During the last 4 years we have seen two very high quality trials co...
journal_title:BJU international
pub_type: 杂志文章,评审
doi:10.1111/j.1464-410X.2012.11172.x
更新日期:2012-06-01 00:00:00
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journal_title:BJU international
pub_type: 杂志文章
doi:10.1111/bju.14210
更新日期:2018-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-11-01 00:00:00