Rationale and design of ATHENA: A placebo-controlled, double-blind, parallel arm Trial to assess the efficacy of dronedarone 400 mg bid for the prevention of cardiovascular Hospitalization or death from any cause in patiENts with Atrial fibrillation/atria

abstract：:Ischemic preconditioning is a phenomenon whereby exposure of the myocardium to a brief episode of ischemia and reperfusion markedly reduces tissue necrosis induced by a subsequent prolonged ischemia. Therefore, it is hoped that elucidation of the mechanism of preconditioning will yield therapeutic strategies capable o...

journal_title：Journal of cardiovascular electrophysiology

authors： Baines CP,Cohen MV,Downey JM

更新日期：1999-05-01 00:00:00

abstract：INTRODUCTION:The objective of this study was to record the ECG of the smallest living mammal to extend the domain of data for comparative AV nodal electrophysiologic purposes. These data are needed to establish the relationship between the PR interval and heart size in mammalian species of all sizes. METHODS AND RESUL...

journal_title：Journal of cardiovascular electrophysiology

authors： van der Tweel LH,Strackee J,Stokhof AA,Wassenaar C,Meijler FL

更新日期：1999-02-01 00:00:00

abstract：INTRODUCTION:We observed a change in the atrial activation sequence during radiofrequency (RF) energy application in patients undergoing left accessory pathway (AP) ablation. This occurred without damage to the AP and in the absence of a second AP or alternative arrhythmia mechanism. We hypothesized that block in a lef...

journal_title：Journal of cardiovascular electrophysiology

authors： Luria DM,Nemec J,Etheridge SP,Compton SJ,Klein RC,Chugh SS,Munger TM,Shen WK,Packer DL,Jahangir A,Rea RF,Hammill SC,Friedman PA

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Successful anticoagulation is critical for stroke prevention in adults with atrial fibrillation (AF). Anticoagulation satisfaction is a key indicator of treatment success. While physical, cognitive, and psychosocial limitations are common in elderly AF patients, their associations with anticoagulation satisf...

journal_title：Journal of cardiovascular electrophysiology

authors： Wang W,Saczynski J,Lessard D,Mailhot T,Barton B,Waring ME,Sogade F,Hayward R,Helm R,McManus DD

更新日期：2019-11-01 00:00:00

abstract：UNLABELLED:Electrical Activity and RhoA in the Embryo. INTRODUCTION:Myocardium at the venous pole (sinus venosus) of the heart has gained clinical interest as arrhythmias can be initiated from this area. During development, sinus venosus myocardium is incorporated to the primary heart tube and expresses different mark...

journal_title：Journal of cardiovascular electrophysiology

authors： Vicente-Steijn R,Kolditz DP,Mahtab EA,Askar SF,Bax NA,VAN DER Graaf LM,Wisse LJ,Passier R,Pijnappels DA,Schalij MJ,Poelmann RE,Gittenberger-DE Groot AC,Jongbloed MR

更新日期：2010-11-01 00:00:00

abstract：INTRODUCTION:The success of pulmonary vein isolation (PVI) for atrial fibrillation (AF) may be improved if stable AF sources identified by Focal Impulse and Rotor Mapping (FIRM) are also eliminated. The long-term results of this approach are unclear outside the centers where FIRM was developed; thus, we assessed outcom...

journal_title：Journal of cardiovascular electrophysiology

authors： Miller JM,Kowal RC,Swarup V,Daubert JP,Daoud EG,Day JD,Ellenbogen KA,Hummel JD,Baykaner T,Krummen DE,Narayan SM,Reddy VY,Shivkumar K,Steinberg JS,Wheelan KR

更新日期：2014-09-01 00:00:00

abstract：INTRODUCTION:The apamin-sensitive small-conductance calcium-activated potassium current (IKAS ) is increased in heart failure. It is unknown if myocardial infarction (MI) is also associated with an increase of IKAS . METHODS AND RESULTS:We performed Langendorff perfusion and optical mapping in 6 normal hearts and 10 h...

journal_title：Journal of cardiovascular electrophysiology

authors： Lee YS,Chang PC,Hsueh CH,Maruyama M,Park HW,Rhee KS,Hsieh YC,Shen C,Weiss JN,Chen Z,Lin SF,Chen PS

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Patients with left bundle branch block (LBBB) undergoing right heart catheterization can develop complete heart block (CHB) or right bundle branch block (RBBB) in response to right bundle branch (RBB) trauma. We hypothesized that LBBB patients with an initial r wave (>or=1 mm) in lead V1 have intact left to ...

journal_title：Journal of cardiovascular electrophysiology

authors： Padanilam BJ,Morris KE,Olson JA,Rippy JS,Walsh MN,Subramanian N,Vidal A,Prystowsky EN,Steinberg LA

更新日期：2010-07-01 00:00:00

abstract：INTRODUCTION:Significant species-, tissue-, and age-dependent differences have been described for the L-type calcium current (ICa). Therefore, extrapolation of data obtained from the many animal models to human cardiac physiology is difficult. In this study, we have characterized the voltage-dependent properties of ICa...

journal_title：Journal of cardiovascular electrophysiology

authors： Cohen NM,Lederer WJ

更新日期：1993-08-01 00:00:00

abstract：:A case of intermittent sinus parasystole in which the parasystolic focus is protected from the dominant sinus rhythm only during the second half of its intrinsic cycle is reported. In addition, a modulating (i.e., electronic) effect is often clearly exerted from the dominant rhythm upon the focus during the protected ...

journal_title：Journal of cardiovascular electrophysiology

authors： Satullo G,Donato A,Busá G,Cavallaro L

更新日期：1996-03-01 00:00:00

abstract：:Pulmonary vein isolation (PVI) is a well-established treatment for atrial fibrillation (AF); however, studies report suboptimal outcomes in persistent AF. Adjuvant ablation targeting the substrate outside the pulmonary veins has been proposed to improve the success rates of the procedure. In this review, we summarize ...

journal_title：Journal of cardiovascular electrophysiology

authors： Terricabras M,Verma A

更新日期：2020-08-01 00:00:00

abstract：INTRODUCTION:The pulmonary veins (PVs) are a dominant source of triggers initiating atrial fibrillation (AF). While recent evidence implicates these structures in the maintenance of paroxysmal AF, their role in permanent AF is not known. The current study aims to compare the contribution of PV activity to the maintenan...

journal_title：Journal of cardiovascular electrophysiology

authors： Sanders P,Nalliah CJ,Dubois R,Takahashi Y,Hocini M,Rotter M,Rostock T,Sacher F,Hsu LF,Jönsson A,O'Neill MD,Jaïs P,Haïssaguerre M

更新日期：2006-09-01 00:00:00

abstract：:Atrial fibrillation is the most common sustained tachyarrhythmia and, as such, has become the recent focus of intense clinical and experimental interest. Because of its associated morbidity and mortality, there is a multidisciplinary effort to understand the pathophysiology that may ultimately lead to improved therape...

journal_title：Journal of cardiovascular electrophysiology

authors： Zipes DP

更新日期：1997-08-01 00:00:00

abstract：:Atrial fibrillation (AF) and congestive heart failure (CHF) are two increasingly common cardiac disorders with a growing prevalence in the overall population. Improved treatment of acute medical conditions has increased the incidence of these cardiac disorders. AF and CHF have similar epidemiologic characteristics and...

journal_title：Journal of cardiovascular electrophysiology

authors： Ehrlich JR,Nattel S,Hohnloser SH

更新日期：2002-04-01 00:00:00

abstract：INTRODUCTION:The clinical role of atrial arrhythmias (AA) in arrhythmogenic right ventricular cardiomyopathy (ARVC) and the echocardiographic variables that predict them are not well defined. We describe the prevalence, types, echocardiographic predictors, and management of AA in patients with ARVC. METHODS:We retrosp...

journal_title：Journal of cardiovascular electrophysiology

authors： Cardona-Guarache R,Åström-Aneq M,Oesterle A,Asirvatham R,Svetlichnaya J,Marcus GM,Gerstenfeld EP,Klein L,Scheinman MM

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:The value of noninvasive markers reflecting repolarization and/or conduction abnormalities in identifying patients with abnormal ECG showing a pattern of atypical right bundle branch block and ST elevation syndrome (Brugada syndrome) at risk for life-threatening arrhythmias is controversial. Because right ...

journal_title：Journal of cardiovascular electrophysiology

authors： Eckardt L,Bruns HJ,Paul M,Kirchhof P,Schulze-Bahr E,Wichter T,Breithardt G,Borggrefe M,Haverkamp W

更新日期：2002-08-01 00:00:00

abstract：INTRODUCTION:Patients with bradycardia requiring permanent pacing frequently suffer from additional atrial tachyarrhythmias (ATs). This study evaluated the safety and efficacy of atrial antitachycardia pacing (ATP) and the performance of pacing for AT prevention implemented into a new pacemaker. METHODS AND RESULTS:In...

journal_title：Journal of cardiovascular electrophysiology

authors： Israel CW,Hügl B,Unterberg C,Lawo T,Kennis I,Hettrick D,Hohnloser SH,AT500 Verification Study Investigators.

更新日期：2001-10-01 00:00:00

abstract：INTRODUCTION:Primary prevention ICD trials have excluded patients with CKD. Comorbidities and lower life expectancy in patients with CKD make the benefit of primary prevention ICD implantation uncertain. METHODS:A decision analysis model was devised to evaluate the risks and benefits of implantable cardioverter-defibr...

journal_title：Journal of cardiovascular electrophysiology

authors： Amin MS,Fox AD,Kalahasty G,Shepard RK,Wood MA,Ellenbogen KA

更新日期：2008-12-01 00:00:00

abstract：INTRODUCTION:Accurate identification of slow conducting regions in patients with scar-related atrial tachycardia (AT) is difficult using conventional electrogram annotation for cardiac electroanatomic mapping (EAM). Estimating delays between neighboring mapping sites is a potential option for activation map computation...

journal_title：Journal of cardiovascular electrophysiology

authors： Vicera JJB,Lin YJ,Lee PT,Chang SL,Lo LW,Hu YF,Chung FP,Lin CY,Chang TY,Tuan TC,Chao TF,Liao JN,Wu CI,Liu CM,Lin CH,Chuang CM,Chen CC,Chin CG,Liu SH,Cheng WH,Tai LP,Huang SH,Chou CY,Lugtu I,Liu CH,Chen SA

更新日期：2020-06-01 00:00:00

abstract：INTRODUCTION:While some posteroseptal and left posterior accessory pathways (APs) can be ablated on the tricuspid annulus or within the coronary venous system, others require a left-sided approach. "Fragmented" or double potentials are frequently recorded in the coronary sinus (CS), with a smaller, blunt component from...

journal_title：Journal of cardiovascular electrophysiology

authors： Pap R,Traykov VB,Makai A,Bencsik G,Forster T,Sághy L

更新日期：2008-07-01 00:00:00

abstract：INTRODUCTION:Catheter ablation is an effective treatment of scar-related ventricular tachycardia (VT), but the overall complexity of the procedure has precluded its widespread use. Remote magnetic navigation (RMN) has been shown to facilitate cardiac mapping and ablation of VT in a retrospective series. STOP-VT is the ...

journal_title：Journal of cardiovascular electrophysiology

authors： Skoda J,Arya A,Garcia F,Gerstenfeld E,Marchlinski F,Hindricks G,Miller J,Petru J,Sediva L,Sha Q,Janotka M,Chovanec M,Waldauf P,Neuzil P,Reddy VY

更新日期：2016-03-01 00:00:00

abstract：:Dual chamber pacemakers have inbuilt advanced safety systems such as ventricular safety standby (crosstalk detection) to prevent ventricular oversensing resulting in inappropriate pacing inhibition. We describe a case where this safety mechanism does not reliably work and the management required to rectify the situati...

journal_title：Journal of cardiovascular electrophysiology

authors： Haldar SK,Steed B,Watkins S,Nair K

更新日期：2017-05-01 00:00:00

abstract：INTRODUCTION:Idiopathic ventricular tachycardia (VT) originating from the left ventricular outflow tract (LVOT) is rare. Previously reported were two cases of LVOT tachycardia which were treated with radiofrequency (RF) catheter ablation through endocardial aortomitral continuity. We report here a case of a repetitive ...

journal_title：Journal of cardiovascular electrophysiology

authors： Shimoike E,Ohnishi Y,Ueda N,Maruyama T,Kaji Y

更新日期：1999-07-01 00:00:00

abstract：INTRODUCTION:ATP-sensitive K+ channels (K(ATP)) are expressed abundantly in cardiovascular tissues. Blocking this channel in experimental models of ischemia can reduce arrhythmias. We investigated the acute effects of amiodarone on the activity of cardiac sarcolemmal K(ATP) channels and their sensitivity to ATP. METHO...

journal_title：Journal of cardiovascular electrophysiology

authors： Holmes DS,Sun ZQ,Porter LM,Bernstein NE,Chinitz LA,Artman M,Coetzee WA

更新日期：2000-10-01 00:00:00

abstract：INTRODUCTION:Ventricular fibrillation and ventricular flutter (cycle length < or = 230 msec) induced at electrophysiologic studies are thought to be nonspecific findings in patients presenting with syncope of unknown origin. However, there are limited data on the prognosis of these patients in long-term follow-up. MET...

journal_title：Journal of cardiovascular electrophysiology

authors： Link MS,Saeed M,Gupta N,Homoud MK,Wang PJ,Estes NA 3rd

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Residual gaps due to incomplete ablation lines are known to be the most common cause of recurrent atrial fibrillation (AF) after catheter ablation. We hypothesized that any residual potentials at the junction of the left atrium and pulmonary vein (PV), inside the circumferential PV ablation (CPVA) lines, wou...

journal_title：Journal of cardiovascular electrophysiology

authors： Kim YH,Lim HE,Pak HN,Kwak JJ,Park JS,Choi JI,Park SW,Kim YH

更新日期：2010-09-01 00:00:00

abstract：:The heart's pacemaker, the sinoatrial node, does not consist of a group of uniform sinoatrial node cells embedded in atrial muscle. Instead, it is a heterogeneous tissue with multiple cell types and a complex structure. Evidence suggests that from the periphery to the center of the sinoatrial node, there is a gradient...

journal_title：Journal of cardiovascular electrophysiology

authors： Boyett MR,Dobrzynski H,Lancaster MK,Jones SA,Honjo H,Kodama I

更新日期：2003-01-01 00:00:00

abstract：:Pulmonary vein (PV) arrhythmogenicity underlying the maintenance of atrial fibrillation (AF) may be explained by three mechanisms: enhanced automaticity, triggered activity, and reentry. There are only a few reports describing sustained PV tachycardias (PVT) following electrical disconnection from the left atrium, in ...

journal_title：Journal of cardiovascular electrophysiology

authors： Rostock T,O'Neill MD,Takahashi Y,Sanders P,Haïssaguerre M

更新日期：2007-04-01 00:00:00

abstract：:Epicardial ablation may be required to eliminate ventricular tachycardia (VT) in patients with underlying structural heart disease. The decision to gain epicardial access is frequently based on the suspicion of an epicardial origin for the VT and/or presence of an arrhythmogenic substrate. Epicardial pathology and VT ...

journal_title：Journal of cardiovascular electrophysiology

authors： Bazan V,Frankel DS,Santangeli P,Garcia FC,Tschabrunn CM,Marchlinski FE

更新日期：2019-03-01 00:00:00

abstract：:Atrial arrhythmias are quite common in patients after heart transplantation; they can occur via focal or reentrant mechanisms and are amenable to curative therapy with catheter ablation. Integration of the individual patient's surgical anatomy with the arrhythmia pattern on 12-lead electrocardiogram can help both to n...

journal_title：Journal of cardiovascular electrophysiology

authors： Dahu MI,Hutchinson MD

更新日期：2012-02-01 00:00:00