Abstract:
BACKGROUND:Multiple Myeloma presenting as a pleural effusion is extremely rare. It is usually a late complication and is associated with a poor prognosis. CASE PRESENTATION:A 40-year-old male presented with dyspnea and fever of six months duration. Clinical diagnosis of pulmonary tuberculosis was considered. X-ray chest showed bilateral pleural effusion. Pleural cytology revealed numerous plasma cells, some of which were binucleated and atypical. Cytological differential diagnosis included: Myelomatous effusion and Non-Hodgkin's Lymphoma deposit (Immunoblastic type). Bone marrow biopsy, serum protein electrophoresis and bone scan confirmed the diagnosis of multiple myeloma (Plasmablastic type). CONCLUSION:Myelomatous pleural effusion as an initial presentation although extremely rare, should always be considered in presence of atypical plasma cells irrespective of age.
journal_name
Cytojournaljournal_title
CytoJournalauthors
Dhingra KK,Singhal N,Nigam S,Jain Sdoi
10.1186/1742-6413-4-17subject
Has Abstractpub_date
2007-09-07 00:00:00pages
17eissn
0974-5963issn
1742-6413pii
1742-6413-4-17journal_volume
4pub_type
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