Abstract:
STUDY DESIGN:An ex vivo biomechanical study using cadaveric vertebral bodies. OBJECTIVE:To determine how bone mineral density (BMD) affects mechanical strength and stiffness of the vertebral body after vertebroplasty, and to determine how the association between mechanical properties and BMD varies with amount of cement injected. SUMMARY OF BACKGROUND DATA:Adverse events associated with vertebroplasty include cement leakage and adjacent fractures. Understanding effects of bone density and cement volume on mechanical properties may be important clinically to identify the minimum cement volume that will benefit the patient while minimizing risks of adverse events. METHODS:The bone mineral density of 13 vertebral columns from adult white female cadavers was measured with DEXA. Vertebral bodies (n = 126) were assigned to 5 groups based on cement treatment: intact, untreated, 4% fill, 12% fill, and 24% fill. Treated specimens were first loaded asymmetrically to simulate a wedge compression fracture before injection with polymethylmethacrylate cement. Strength and stiffness were measured in axial compression. RESULTS:Only the highest cement dose used (24% fill, 7 mL on average) had an effect on mechanical stiffness or strength. Within this group, stiffness was improved relative to untreated fractures but not restored to prefracture levels, and strength was enhanced beyond intact values. These improvements in stiffness and strength depended significantly on bone density, with highly osteoporotic samples benefitting the least. CONCLUSION:Results suggest that highly osteoporotic patients may receive the least amount of improvement in mechanical properties after vertebroplasty. It is recommended, therefore, that cement volume be restricted to the amount needed for fracture reduction only because there may be a limit to the mechanical benefits that additional cement can offer, depending on patient bone density. Understanding these limitations can potentially minimize risks of adverse events.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Graham J,Ahn C,Hai N,Buch BDdoi
10.1097/BRS.0b013e318133fc73subject
Has Abstractpub_date
2007-08-15 00:00:00pages
E505-11issue
18eissn
0362-2436issn
1528-1159pii
00007632-200708150-00024journal_volume
32pub_type
杂志文章相关文献
SPINE文献大全abstract:STUDY DESIGN:A review of 60 surgical cases for correction of scoliosis, during which neuromotor evoked potentials and somatosensory evoked potentials were monitored. OBJECTIVES:To determine the validity and reliability of intraoperative neuromotor evoked potential monitoring in cases of scoliosis, where damage to the ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199910010-00012
更新日期:1999-10-01 00:00:00
abstract:STUDY DESIGN:A controlled rabbit model of lumbar posterolateral intertransverse process arthrodesis was used to evaluate a bone graft substitute. OBJECTIVE:To determine the efficacy of demineralized bone matrix gel as an autograft extender, using different ratios of demineralized bone matrix to autograft and to determ...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/00007632-199801150-00003
更新日期:1998-01-15 00:00:00
abstract:STUDY DESIGN:Cadaveric laboratory study. OBJECTIVE:To compare the accuracy, efficiency, and safety of intraoperative cone beam-computed tomography with navigation (O-ARM) with traditional intraoperative fluoroscopy (C-ARM) for the placement of pedicle screws. SUMMARY OF BACKGROUND DATA:Radiation exposure remains a co...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3182a51d1e
更新日期:2013-10-15 00:00:00
abstract:STUDY DESIGN:An ambispective analysis. OBJECTIVE:The aim of this study was to report the global prevalence of specific degenerative cervical pathologies in patients with degenerative cervical myelopathy (DCM) through detailed review of magnetic resonance imaging (MRIs). SUMMARY OF BACKGROUND DATA:DCM encompasses a sp...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001981
更新日期:2017-07-15 00:00:00
abstract:STUDY DESIGN:A study examining the clinical protocol of scoliosis wound irrigation, demonstrating povidone-iodine's (PVI) effect on human osteoblast cells. Primary and immortal cell line osteoblasts were treated with 0.35% PVI for 3 minutes, and analyzed for proliferation rate, oxidative capacity, and mineralization. ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001332
更新日期:2016-05-01 00:00:00
abstract:STUDY DESIGN:This is a technical note and review of the literature. OBJECTIVE:We propose to describe a revised surgical technique of C1 lateral mass screw insertion with protection of C1-C2 venous sinus surrounding the C2 nerve root. SUMMARY OF BACKGROUND DATA:During C1 lateral mass screw insertion and in posterior C...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0b013e3181e215ff
更新日期:2010-10-01 00:00:00
abstract:STUDY DESIGN:A rat tail model was used to test the hypothesis that angulation and asymmetric axial compressive loading would lead to vertebral wedging because of asymmetric longitudinal growth in the physes. OBJECTIVES:To study the effect of angulation and asymmetric loading on the progression of spinal curvature in a...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199706150-00003
更新日期:1997-06-15 00:00:00
abstract:STUDY DESIGN:An in vitro human cadaveric study comparing the effects of anterior and posterior sequential destabilization conditions on thoracic functional unit mechanics was studied. OBJECTIVES:To investigate the biomechanical properties of the human thoracic spine. SUMMARY OF BACKGROUND DATA:Few studies have addres...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200202010-00007
更新日期:2002-02-01 00:00:00
abstract:STUDY DESIGN:This is a 3-year prospective study of juvenile low back pain (LBP). OBJECTIVES:To investigate persistence and change in LBP. SUMMARY OF BACKGROUND DATA:Earlier episodes of LBP are a strong risk factor for LBP in adults, while the persistence of LBP through adolescence is not known. METHODS:The material ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000143666.58758.8b
更新日期:2004-11-01 00:00:00
abstract:STUDY DESIGN:Prospective trial. OBJECTIVE:To perform a precise anatomical study of the presacral space and to examine the approach safety of AxiaLIF (axial lumbar interbody fusion) in an anatomical aspect. SUMMARY OF BACKGROUND DATA:AxiaLIF is a novel, minimally invasive surgery. Though there were a few clinical repo...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31821b8f6d
更新日期:2012-02-15 00:00:00
abstract::The human spinal column, devoid of musculature, is incapable of carrying normal physiologic loads. In an in vitro experiment, the effect of simulated intersegmental muscle forces on spinal instability was investigated. Intact and sequentially injured fresh lumbar functional spinal units were subjected to three-dimensi...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198902000-00008
更新日期:1989-02-01 00:00:00
abstract:STUDY DESIGN:Experimental animal study. OBJECTIVE:To investigate the interaction between magnetically controlled growing rods (MCGRs) and magnetic resonance imaging (MRI). SUMMARY OF BACKGROUND DATA:Growing rod treatment through serial operations results in adverse effects on the patient and high treatment costs. MCG...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001880
更新日期:2017-05-01 00:00:00
abstract:STUDY DESIGN:Fifty-two practices in the East Midlands, United Kingdom, were included. OBJECTIVES:To test the hypothesis that referral for lumbar spine radiography is cost-effective in primary care patients with low back pain of at least 6 weeks' duration compared with usual care in which referral is not routine. SUMM...
journal_title:Spine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007632-200210150-00021
更新日期:2002-10-15 00:00:00
abstract:OBJECTIVES:To focus attention of the clinician on the anatomy and (patho)physiology of the vertebral venous system, so as to offer a tool to better understand and anticipate (potential) complications that are related to the application of percutaneous vertebroplasty and kyphoplasty. BACKGROUND:Percutaneous vertebropla...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/01.brs.0000128758.64381.75
更新日期:2004-07-01 00:00:00
abstract:STUDY DESIGN:Case series. OBJECTIVE:Presentation of results of dorsal root entry zone lesions in 10 patients suffering from severe neuropathic pain due to brachial plexopathy or radiation-induced trigeminal neuropathy. SUMMARY OF BACKGROUND DATA:Radiation-induced neuropathy is an uncommon but serious complication of ...
journal_title:Spine
pub_type: 临床试验,杂志文章
doi:10.1097/01.brs.0000261541.97749.e7
更新日期:2007-05-01 00:00:00
abstract::The detection of the posterior edge of the L4-L5 intervertebral disc has been accomplished by applying digital image processing techniques on conventional lateral radiograms of the spine, and the method is described. The results of this study have shown that there can be substantial absorption at the site of the disc ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198209000-00016
更新日期:1982-09-01 00:00:00
abstract:STUDY DESIGN:Retrospective cohort study of the American College of Surgeons National Surgical Quality Improvement Program database from 2011 to 2012. OBJECTIVE:Minimizing the morbidity of posterior cervical fusion can be improved with identification of patient risk factors. SUMMARY OF BACKGROUND DATA:Posterior cervic...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001564
更新日期:2016-10-01 00:00:00
abstract:STUDY DESIGN:An immunohistochemical examination of the presence of inflammatory cells in routinely processed resection specimens of the lumbar disc, and a comparison of the histologic results with clinical data collected prospectively before and after surgery. OBJECTIVES:To assess the influence of inflammatory reactio...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200004010-00017
更新日期:2000-04-01 00:00:00
abstract:STUDY DESIGN:In vitro study to determine occupational radiation exposure during lumbar fluoroscopy. OBJECTIVES:To assess radiation exposure to the spine surgeon during fluoroscopically assisted thoracolumbar pedicle screw placement. SUMMARY OF BACKGROUND DATA:Occupational radiation exposure during a variety of fluoro...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200010150-00016
更新日期:2000-10-15 00:00:00
abstract::A retrospective study was done to determine the entire clinical spectrum of lumbar spine disease in 47 adult patients, averaging 27.6 years of age, with achondroplasia. Five distinct clinical categories were defined. Twenty-eight percent of the patients were asymptomatic; 28% had only mechanical or degenerative lumbar...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198203000-00008
更新日期:1982-03-01 00:00:00
abstract:STUDY DESIGN:Retrospective study of posterior hemivertebra resection and osteotomies with transpedicular instrumentation in very young children. OBJECTIVE:Assessment of early intervention in congenital scoliosis with almost complete correction of the main deformity. SUMMARY OF BACKGROUND DATA:There is a trend to earl...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181ab6290
更新日期:2009-08-01 00:00:00
abstract:STUDY DESIGN:A retrospective case-control study. OBJECTIVE:This study aimed to elucidate the association between facet joint orientation and degenerative lumbar spinal stenosis (DLSS). SUMMARY OF BACKGROUND DATA:Many studies have demonstrated the relationship between sagittal facet orientation and degenerative lumbar...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000002493
更新日期:2018-07-15 00:00:00
abstract:STUDY DESIGN:Retrospective cohort study. OBJECTIVE:The fusion risk score (FRS) is introduced to assess baseline risk of spine fusion surgery preoperatively. An objective method of stratifying risk allows the surgeon to control risk through tailoring intervention and explain differences in complication profile in high-...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3182a8c3b7
更新日期:2013-12-01 00:00:00
abstract:STUDY DESIGN:A restrospective review of 81 cases of osteoid osteoma of the mobile spine submitted to surgical treatment. OBJECTIVE:Analyze pro and contras of different techniques (conventional and minimally invasive) for the treatment of osteoid osteoma. SUMMARY OF BACKGROUND DATA:Intralesional excision has been cons...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181ffeb5e
更新日期:2011-11-15 00:00:00
abstract:STUDY DESIGN:Retrospective cohort study. OBJECTIVE:This study aimed to identify the rates and causes of unplanned hospital readmission at 30 days and 1 year after surgical treatment of primary and metastatic spinal tumors. SUMMARY OF BACKGROUND DATA:Primary spine tumors and non-spine tumors metastatic to the spine ca...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000000517
更新日期:2014-10-01 00:00:00
abstract:STUDY DESIGN:In vitro biomechanical study to evaluate the stability of different types of instrumentation in the lumbar spine following corpectomy in relation to bone mineral density (BMD). OBJECTIVES:To investigate the relation between the stability of a spinal instrumentation and BMD. To determine a threshold value ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000161000.36376.c5
更新日期:2005-05-01 00:00:00
abstract:STUDY DESIGN:Retrospective study. OBJECTIVE:Compare outcomes of different treatment methods for intraspinal synovial cysts. SUMMARY OF BACKGROUND DATA:Intraspinal synovial cysts are cited as an increasing cause of back pain and radiculopathy. To date, few studies have compared outcomes of differing treatment methods ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181bdafed
更新日期:2010-05-01 00:00:00
abstract:STUDY DESIGN:Systematic literature review and expert survey OBJECTIVE.: The aim of this study was to determine factors associated with neurologic improvement in patients with neurologic deficits secondary to metastatic epidural spinal cord compression (MESCC). Clear understanding of these factors will guide surgical de...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0000000000001827
更新日期:2016-10-15 00:00:00
abstract::The "Back-Pain Institute" at Sundsvall offers an advanced rehabilitation program to people with long-standing back pain. This program has been evaluated in a controlled prospective study. Data were gathered from questionnaires mailed on three occasions, from the sick insurance office and from the bureau of employment....
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198404000-00018
更新日期:1984-04-01 00:00:00
abstract:STUDY DESIGN:A 2-group experimental design. OBJECTIVE:To investigate the effect of a cognitive dual-task on postural sway of pelvis and trunk during unstable sitting in nonspecific chronic patients with low back pain (CLBP) compared to healthy control subjects. SUMMARY OF BACKGROUND DATA:Higher cognitive systems as w...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181b4fe4d
更新日期:2010-03-01 00:00:00