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FSDB: a frameshift signal database.

Abstract：

:Programmed frameshifting is a recoding event in which a ribosome shifts reading frame by one or more nucleotides at a specific mRNA signal between overlapping genes. Programmed frameshifting is involved in the expression of many genes in a wide range of organisms, especially in viruses and bacteria. The mechanism of programmed frameshifting is not fully understood despite many studies, and there are few databases available for detailed information on programmed frameshifting. We have developed a database called FSDB (Frameshift Signal Database), which is a comprehensive compilation of experimentally known or computationally predicted data about programmed ribosomal frameshifting. FSDB provides a graphical view of frameshift signals and the genes using programmed frameshifting for their expression. It also allows the user himself/herself to find programmed frameshift sites in genomic sequences using a program called FSFinder (http://wilab.inha.ac.kr/fsfinder2). We believe FSDB will be a valuable resource for scientists studying programmed ribosomal frameshifting. FSDB is freely accessible at http://wilab.inha.ac.kr/fsdb/.

journal_name

Comput Biol Chem

journal_title

Computational biology and chemistry

authors

Moon S,Byun Y,Han K

doi

10.1016/j.compbiolchem.2007.05.004

subject

Has Abstract

pub_date

2007-08-01 00:00:00

pages

298-302

issue

4

eissn

1476-9271

issn

1476-928X

pii

S1476-9271(07)00079-5

journal_volume

31

pub_type

杂志文章

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