Abstract:
OBJECTIVE:Even though persistent organic pollutants (POPs) are well-known neurotoxicants, there is no previous study, even cross-sectional, on the association between background exposure to POPs and clinically significant developmental disorders, such as learning disability (LD) or attention deficit disorder (ADD), among children from a general population. DESIGN:Cross-sectional study. SETTING:Study subjects were 278 children aged 12-15 years included in the National Health and Nutrition Examination Survey 1999-2000. The seven most commonly detected POPs (each detectable in >/=20% of children: 3,3',4,4',5-pentachlorobiphenyl; 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (HPCDD); 1,2,3,4,6,7,8,9-octachlorodibenzo-p-dioxin (OCDD); 1,2,3,4,6,7,8-heptachlorodibenzofuran (HPCDF); beta-hexachlorocyclohexane; p,p'-dichlorodiphenyltrichloroethane; and trans-nonachlor) were selected. MAIN RESULTS:Compared with children with non-detectable levels of POPs, adjusted prevalence ORs (95% CIs) of LD among those with detectable levels of HPCDD, OCDD or HPCDF were 2.08 ( 1.17 to 3.68), 2.72 (1.24 to 5.99) and 2.18 (1.15 to 4.15), respectively. For ADD, the corresponding figures were 3.41 (1.08 to 10.8), 3.33 (0.94 to 11.8) and 2.31 (0.62 to 8.63), respectively. CONCLUSIONS:Associations were observed between serum concentrations of POPs belonging to the categories of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans and the prevalence of two clinically significant development problems, LD and ADD. The nature of these associations needs to be clarified by prospective studies.
journal_name
J Epidemiol Community Healthjournal_title
Journal of epidemiology and community healthauthors
Lee DH,Jacobs DR,Porta Mdoi
10.1136/jech.2006.054700subject
Has Abstractpub_date
2007-07-01 00:00:00pages
591-6issue
7eissn
0143-005Xissn
1470-2738pii
61/7/591journal_volume
61pub_type
杂志文章abstract:OBJECTIVE:To assess the value of psychosocial risk factors in discriminating between individuals at higher and lower risk of coronary heart disease, using risk prediction equations. DESIGN:Prospective observational study. SETTING:Scotland. PARTICIPANTS:5191 employed men aged 35 to 64 years and free of coronary heart...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2006.055921
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND:Although trouble sleeping is a common problem among women at mid-life, patterns in trouble sleeping relating to social and health-related risk factors are unclear. This analysis describes the dynamics of trouble sleeping among women at mid-life. METHODS:The National Survey of Health and Development is a nat...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,多中心研究
doi:10.1136/jech.2008.079616
更新日期:2009-12-01 00:00:00
abstract::Socioeconomic differentials in the uptake of medical care in men were investigated using data from the General Household Survey (1974-76 and 1979-80). Hospitalisation, attendance at out patient clinics, and consultation with doctors were higher in local authority tenants than in owner occupiers. Men belonging to the m...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.41.3.196
更新日期:1987-09-01 00:00:00
abstract:BACKGROUND:This study investigated the impact of the Healthy Housing Programme in reducing acute hospitalisations in South Auckland, New Zealand. The programme involved house modifications to reduce overcrowding, insulation and ventilation improvements, and health and social service assessments, referrals and linkages....
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2009.107441
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVES:To report on the development of computer assisted methods for linking medical records and record abstracts. DESIGN:The methods include file blocking, to put records in an order which makes searching efficient; matching, which is the process of comparing records to determine whether they do or do not relate ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.47.4.316
更新日期:1993-08-01 00:00:00
abstract:STUDY OBJECTIVE:To estimate the relative health effects of the income and health insurance provisions of the Los Angeles City living wage ordinance. SETTING AND PARTICIPANTS:About 10 000 employees of city contractors are subject to the Los Angeles City living wage ordinance, which establishes an annually adjusted mini...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2004.028142
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVE:This paper aims to show that, compared with young women, there is an apparent discrepancy in the reported sexual behaviour of young men and records of their fatherhood. DESIGN:The data come from four studies of the sexual behaviour of young people in various parts of Britain between 1960 and 1990 and from st...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.48.1.52
更新日期:1994-02-01 00:00:00
abstract:STUDY OBJECTIVE:Although national variation in short-term prognosis (that is, 30 day mortality) after a patient's first hospitalisation for heart failure may depend on individual differences between patients, dissimilarities in hospital practices may also influence prognosis. This study, therefore, sought to disentangl...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.55.5.323
更新日期:2001-05-01 00:00:00
abstract:STUDY OBJECTIVES:To assess the incidence of seroconversion and seroreversion in IgG antibodies to Helicobacter pylori within a 11 year observation period using these events as markers for acquisition and loss of the infection, respectively. DESIGN:Population based prospective cohort study. SETTING:Northern part of Co...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.54.6.444
更新日期:2000-06-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.47.2.127
更新日期:1993-04-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2011-200038
更新日期:2012-12-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2007.063909
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:A reduction in sex ratio at live birth has been proposed as a sentinel health indicator that can be used to monitor the health of populations. OBJECTIVE:To test the hypothesis that a lower sex ratio is associated with adverse national population health using the prevalences of HIV and tuberculosis as measur...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2011-200744
更新日期:2013-04-01 00:00:00
abstract::More than 30 years ago, the older of us published a paper with the proposal that all scientific papers should start with a statement along the lines of: "These are the opinions on which I base my facts". Why pretend? To take a topical example, if you are on the nature side of the nature/nurture debates, is it likely t...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2008.081695
更新日期:2008-12-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2014-204535
更新日期:2015-03-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,评审
doi:10.1136/jech-2014-204091
更新日期:2015-01-01 00:00:00
abstract::Health equity is increasingly present as an overarching goal in public health policy frameworks across the globe. Public health actions to support health equity are challenging because solutions to the root causes of health inequities often lie outside of the health sector, and a specific role for environmental public...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2018-210843
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Research on inequalities in health has shown a strong association between the lack of standard of living (defined as material deprivation) and self-rated health (SRH). In this study, we sought to further examine this association in a trend analysis of relative and absolute inequalities in SRH as defined by m...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2015-205948
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Mortality, incidence of most diseases, and prevalence of adverse health behaviours follow an inverse gradient with social class. Many proxies for socioeconomic status (SES) exist; however, each bears a different relation to health outcomes, probably following a different aetiological pathway. Additionally, d...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2008.084723
更新日期:2011-03-01 00:00:00
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journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.46.4.425
更新日期:1992-08-01 00:00:00
abstract:STUDY OBJECTIVE:To investigate age, period, and cohort effects on functional status. DESIGN:A prospective cohort study with measurements in 1981, 1990, and 1996. SETTING:Three municipalities in north east Finland. PARTICIPANTS:A regionally representative sample of 19 to 63 year old men and women was drawn from the c...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.56.12.905
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:Early family-level and social-level stressors are both assumed to be the components of two main path models explaining the association between exposure to interparental violence in childhood and its long-term consequences on mental health explored through life-course epidemiological studies. AIMS:To investi...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2008.077750
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:This study investigates social inequalities in self-rated health dynamics for working-aged adults in four nations, representing distinct welfare regime types. The aims are to describe average national trajectories of self-rated health over a 7-year period, identify social determinants of cross-sectional and ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2009.091199
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:To examine the association between socioeconomic status (SES) and risk of frailty, and to assess whether behavioural and clinical factors (BCF) mediate this association. METHODS:Cohort of 1857 non-institutionalised individuals aged ≥ 60 years recruited in 2008-2010 and followed through 2012. Education, occu...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2015-206406
更新日期:2016-04-01 00:00:00
abstract:INTRODUCTION:Health inequalities can be observed in early life as unfavourable birth outcomes. Evidence indicates that neighbourhood socioeconomic circumstances influence health. However, studies looking into temporal trends in inequalities in birth outcomes including neighbourhood socioeconomic conditions are scarce. ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2019-213162
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Childhood mortality is a well-known public health issue, particularly in the low and middle income countries. The overarching aim of this study was to examine whether neighbourhood socioeconomic disadvantage is associated with childhood mortality beyond individual-level measures of socioeconomic status in Ni...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2015-205457
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Exposure to childhood household dysfunction increases the risk of psychiatric morbidity. Although school performance also has been linked with psychiatric morbidity, limited research has considered school performance as a mediating factor. To address this gap in the literature, the current register study exa...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2015-206329
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To study the association between own education, adult and parental circumstances and the risk of myocardial infarction in a former communist country. DESIGN:Population based case-control study. SETTING:General population of five districts of the Czech Republic in the age group 25-64 years. PARTICIPANTS:Ran...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.54.2.91
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:This study examined the prospective association of workplace social capital (WSC) with major depressive episode (MDE) among Japanese employees. METHODS:A 3-year prospective cohort study was conducted among 1058 employees from a private think-tank company who participated in a baseline survey; after excludin...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2016-208561
更新日期:2017-06-01 00:00:00
abstract::Numerous commentaries plea for the use of methods that take into account complexity when evaluating health programmes. These commentaries provide compelling arguments on why evaluations of health programmes should not rely exclusively on methods that were designed for making universal claims about whether and to what ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2020-214027
更新日期:2021-01-01 00:00:00