Association of serum concentrations of persistent organic pollutants with the prevalence of learning disability and attention deficit disorder.

Abstract:

OBJECTIVE:Even though persistent organic pollutants (POPs) are well-known neurotoxicants, there is no previous study, even cross-sectional, on the association between background exposure to POPs and clinically significant developmental disorders, such as learning disability (LD) or attention deficit disorder (ADD), among children from a general population. DESIGN:Cross-sectional study. SETTING:Study subjects were 278 children aged 12-15 years included in the National Health and Nutrition Examination Survey 1999-2000. The seven most commonly detected POPs (each detectable in >/=20% of children: 3,3',4,4',5-pentachlorobiphenyl; 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (HPCDD); 1,2,3,4,6,7,8,9-octachlorodibenzo-p-dioxin (OCDD); 1,2,3,4,6,7,8-heptachlorodibenzofuran (HPCDF); beta-hexachlorocyclohexane; p,p'-dichlorodiphenyltrichloroethane; and trans-nonachlor) were selected. MAIN RESULTS:Compared with children with non-detectable levels of POPs, adjusted prevalence ORs (95% CIs) of LD among those with detectable levels of HPCDD, OCDD or HPCDF were 2.08 ( 1.17 to 3.68), 2.72 (1.24 to 5.99) and 2.18 (1.15 to 4.15), respectively. For ADD, the corresponding figures were 3.41 (1.08 to 10.8), 3.33 (0.94 to 11.8) and 2.31 (0.62 to 8.63), respectively. CONCLUSIONS:Associations were observed between serum concentrations of POPs belonging to the categories of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans and the prevalence of two clinically significant development problems, LD and ADD. The nature of these associations needs to be clarified by prospective studies.

authors

Lee DH,Jacobs DR,Porta M

doi

10.1136/jech.2006.054700

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

591-6

issue

7

eissn

0143-005X

issn

1470-2738

pii

61/7/591

journal_volume

61

pub_type

杂志文章
  • Does consideration of either psychological or material disadvantage improve coronary risk prediction? Prospective observational study of Scottish men.

    abstract:OBJECTIVE:To assess the value of psychosocial risk factors in discriminating between individuals at higher and lower risk of coronary heart disease, using risk prediction equations. DESIGN:Prospective observational study. SETTING:Scotland. PARTICIPANTS:5191 employed men aged 35 to 64 years and free of coronary heart...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2006.055921

    authors: Macleod J,Metcalfe C,Smith GD,Hart C

    更新日期:2007-09-01 00:00:00

  • Patterns in trouble sleeping among women at mid-life: results from a British prospective cohort study.

    abstract:BACKGROUND:Although trouble sleeping is a common problem among women at mid-life, patterns in trouble sleeping relating to social and health-related risk factors are unclear. This analysis describes the dynamics of trouble sleeping among women at mid-life. METHODS:The National Survey of Health and Development is a nat...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章,多中心研究

    doi:10.1136/jech.2008.079616

    authors: Tom SE,Kuh D,Guralnik JM,Mishra GD

    更新日期:2009-12-01 00:00:00

  • Socioeconomic differentials in the uptake of medical care in Great Britain.

    abstract::Socioeconomic differentials in the uptake of medical care in men were investigated using data from the General Household Survey (1974-76 and 1979-80). Hospitalisation, attendance at out patient clinics, and consultation with doctors were higher in local authority tenants than in owner occupiers. Men belonging to the m...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.41.3.196

    authors: Balarajan R,Yuen P,Machin D

    更新日期:1987-09-01 00:00:00

  • Reduced acute hospitalisation with the healthy housing programme.

    abstract:BACKGROUND:This study investigated the impact of the Healthy Housing Programme in reducing acute hospitalisations in South Auckland, New Zealand. The programme involved house modifications to reduce overcrowding, insulation and ventilation improvements, and health and social service assessments, referrals and linkages....

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2009.107441

    authors: Jackson G,Thornley S,Woolston J,Papa D,Bernacchi A,Moore T

    更新日期:2011-07-01 00:00:00

  • Computerised linking of medical records: methodological guidelines.

    abstract:OBJECTIVES:To report on the development of computer assisted methods for linking medical records and record abstracts. DESIGN:The methods include file blocking, to put records in an order which makes searching efficient; matching, which is the process of comparing records to determine whether they do or do not relate ...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.47.4.316

    authors: Gill L,Goldacre M,Simmons H,Bettley G,Griffith M

    更新日期:1993-08-01 00:00:00

  • Projected health impact of the Los Angeles City living wage ordinance.

    abstract:STUDY OBJECTIVE:To estimate the relative health effects of the income and health insurance provisions of the Los Angeles City living wage ordinance. SETTING AND PARTICIPANTS:About 10 000 employees of city contractors are subject to the Los Angeles City living wage ordinance, which establishes an annually adjusted mini...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2004.028142

    authors: Cole BL,Shimkhada R,Morgenstern H,Kominski G,Fielding JE,Wu S

    更新日期:2005-08-01 00:00:00

  • Why don't more young men in the UK become fathers?

    abstract:OBJECTIVE:This paper aims to show that, compared with young women, there is an apparent discrepancy in the reported sexual behaviour of young men and records of their fatherhood. DESIGN:The data come from four studies of the sexual behaviour of young people in various parts of Britain between 1960 and 1990 and from st...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.48.1.52

    authors: Cartwright A

    更新日期:1994-02-01 00:00:00

  • Survival after initial hospitalisation for heart failure: a multilevel analysis of patients in Swedish acute care hospitals.

    abstract:STUDY OBJECTIVE:Although national variation in short-term prognosis (that is, 30 day mortality) after a patient's first hospitalisation for heart failure may depend on individual differences between patients, dissimilarities in hospital practices may also influence prognosis. This study, therefore, sought to disentangl...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.55.5.323

    authors: Merlo J,Ostergren PO,Broms K,Bjorck-Linné A,Liedholm H

    更新日期:2001-05-01 00:00:00

  • Seroconversion and seroreversion in IgG antibodies to Helicobacter pylori: a serology based prospective cohort study.

    abstract:STUDY OBJECTIVES:To assess the incidence of seroconversion and seroreversion in IgG antibodies to Helicobacter pylori within a 11 year observation period using these events as markers for acquisition and loss of the infection, respectively. DESIGN:Population based prospective cohort study. SETTING:Northern part of Co...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.54.6.444

    authors: Rosenstock S,Jørgensen T,Andersen L,Bonnevie O

    更新日期:2000-06-01 00:00:00

  • Maintaining evaluation designs in long term community based health promotion programmes: Heartbeat Wales case study.

    abstract:STUDY OBJECTIVE:To examine the difficulties of developing and maintaining outcome evaluation designs in long term, community based health promotion programmes. DESIGN:Semistructured interviews of health promotion managers. SETTING:Wales and two reference health regions in England. PARTICIPANTS:Nine health promotion ...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.47.2.127

    authors: Nutbeam D,Smith C,Murphy S,Catford J

    更新日期:1993-04-01 00:00:00

  • Translating research for evidence-based public health: key concepts and future directions.

    abstract::Applying research to guide evidence-based practice is an ongoing and significant challenge for public health. Developments in the emerging field of 'translation' have focused on different aspects of the problem, resulting in competing frameworks and terminology. In this paper the scope of 'translation' in public healt...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2011-200038

    authors: Rychetnik L,Bauman A,Laws R,King L,Rissel C,Nutbeam D,Colagiuri S,Caterson I

    更新日期:2012-12-01 00:00:00

  • Adjusting a relative-risk estimate for study imperfections.

    abstract::A statistical analysis combines data with assumptions to yield a quantitative result that is a function of both. One goal of an epidemiological analysis, then, should be to combine data with good assumptions. Unfortunately, a typical quantitative epidemiological analysis combines data with an assumption for which ther...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2007.063909

    authors: Maldonado G

    更新日期:2008-07-01 00:00:00

  • Is the human sex ratio at birth a sentinel health indicator that is associated with HIV/AIDS and tuberculosis prevalences in the 21st century?

    abstract:BACKGROUND:A reduction in sex ratio at live birth has been proposed as a sentinel health indicator that can be used to monitor the health of populations. OBJECTIVE:To test the hypothesis that a lower sex ratio is associated with adverse national population health using the prevalences of HIV and tuberculosis as measur...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2011-200744

    authors: Shifotoka A,Fogarty AW

    更新日期:2013-04-01 00:00:00

  • Global health equity: evidence for action on the social determinants of health.

    abstract::More than 30 years ago, the older of us published a paper with the proposal that all scientific papers should start with a statement along the lines of: "These are the opinions on which I base my facts". Why pretend? To take a topical example, if you are on the nature side of the nature/nurture debates, is it likely t...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2008.081695

    authors: Marmot M,Friel S

    更新日期:2008-12-01 00:00:00

  • First population-level effectiveness evaluation of a national programme to prevent HIV transmission from mother to child, South Africa.

    abstract:BACKGROUND:There is a paucity of data on the national population-level effectiveness of preventing mother-to-child transmission (PMTCT) programmes in high-HIV-prevalence, resource-limited settings. We assessed national PMTCT impact in South Africa (SA), 2010. METHODS:A facility-based survey was conducted using a strat...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2014-204535

    authors: Goga AE,Dinh TH,Jackson DJ,Lombard C,Delaney KP,Puren A,Sherman G,Woldesenbet S,Ramokolo V,Crowley S,Doherty T,Chopra M,Shaffer N,Pillay Y,South Africa PMTCT Evaluation Team.

    更新日期:2015-03-01 00:00:00

  • Fetal ultrasound measurements and associations with postnatal outcomes in infancy and childhood: a systematic review of an emerging literature.

    abstract:BACKGROUND:Several hypotheses predict that faltering fetal growth is an antecedent for common non-communicable diseases. This is the first systematic review of an emerging literature linking antenatal fetal measurements to postnatal outcomes. METHODS:Electronic databases (OVID, EMBASE and Google Scholar) and cohort st...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章,评审

    doi:10.1136/jech-2014-204091

    authors: Alkandari F,Ellahi A,Aucott L,Devereux G,Turner S

    更新日期:2015-01-01 00:00:00

  • Glossary of health equity in the context of environmental public health practice.

    abstract::Health equity is increasingly present as an overarching goal in public health policy frameworks across the globe. Public health actions to support health equity are challenging because solutions to the root causes of health inequities often lie outside of the health sector, and a specific role for environmental public...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2018-210843

    authors: Rideout K,Oickle D

    更新日期:2019-09-01 00:00:00

  • Widening inequalities in self-rated health by material deprivation? A trend analysis between 2001 and 2011 in Germany.

    abstract:BACKGROUND:Research on inequalities in health has shown a strong association between the lack of standard of living (defined as material deprivation) and self-rated health (SRH). In this study, we sought to further examine this association in a trend analysis of relative and absolute inequalities in SRH as defined by m...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2015-205948

    authors: Pförtner TK,Elgar FJ

    更新日期:2016-01-01 00:00:00

  • A two-county comparison of the HOUSES index on predicting self-rated health.

    abstract:BACKGROUND:Mortality, incidence of most diseases, and prevalence of adverse health behaviours follow an inverse gradient with social class. Many proxies for socioeconomic status (SES) exist; however, each bears a different relation to health outcomes, probably following a different aetiological pathway. Additionally, d...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2008.084723

    authors: Butterfield MC,Williams AR,Beebe T,Finnie D,Liu H,Liesinger J,Sloan J,Wheeler PH,Yawn B,Juhn YJ

    更新日期:2011-03-01 00:00:00

  • Fair, and still a sun lover: risk of gallstone formation.

    abstract:STUDY OBJECTIVE:The aim was to evaluate the hypothesis that sunlight exposure leads to the development of gallstones in people with a sun sensitive skin. DESIGN AND SETTING:This was a case-control study among 206 white patients referred for an ultrasound examination of the gallbladder. Sunlight exposure and skin sensi...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.46.4.425

    authors: Pavel S,Thijs CT,Potocky V,Knipschild PG

    更新日期:1992-08-01 00:00:00

  • Improved functional status in 16 years of follow up of middle aged and elderly men and women in north eastern Finland.

    abstract:STUDY OBJECTIVE:To investigate age, period, and cohort effects on functional status. DESIGN:A prospective cohort study with measurements in 1981, 1990, and 1996. SETTING:Three municipalities in north east Finland. PARTICIPANTS:A regionally representative sample of 19 to 63 year old men and women was drawn from the c...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.56.12.905

    authors: Malmberg JJ,Miilunpalo SI,Vuori IM,Pasanen ME,Oja P,Haapanen-Niemi NA

    更新日期:2002-12-01 00:00:00

  • Exposure to interparental violence and psychosocial maladjustment in the adult life course: advocacy for early prevention.

    abstract:BACKGROUND:Early family-level and social-level stressors are both assumed to be the components of two main path models explaining the association between exposure to interparental violence in childhood and its long-term consequences on mental health explored through life-course epidemiological studies. AIMS:To investi...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2008.077750

    authors: Roustit C,Renahy E,Guernec G,Lesieur S,Parizot I,Chauvin P

    更新日期:2009-07-01 00:00:00

  • Social influences on trajectories of self-rated health: evidence from Britain, Germany, Denmark and the USA.

    abstract:BACKGROUND:This study investigates social inequalities in self-rated health dynamics for working-aged adults in four nations, representing distinct welfare regime types. The aims are to describe average national trajectories of self-rated health over a 7-year period, identify social determinants of cross-sectional and ...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2009.091199

    authors: Sacker A,Worts D,McDonough P

    更新日期:2011-02-01 00:00:00

  • Contribution of health behaviours and clinical factors to socioeconomic differences in frailty among older adults.

    abstract:BACKGROUND:To examine the association between socioeconomic status (SES) and risk of frailty, and to assess whether behavioural and clinical factors (BCF) mediate this association. METHODS:Cohort of 1857 non-institutionalised individuals aged ≥ 60 years recruited in 2008-2010 and followed through 2012. Education, occu...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2015-206406

    authors: Soler-Vila H,García-Esquinas E,León-Muñoz LM,López-García E,Banegas JR,Rodríguez-Artalejo F

    更新日期:2016-04-01 00:00:00

  • Persisting inequalities in birth outcomes related to neighbourhood deprivation.

    abstract:INTRODUCTION:Health inequalities can be observed in early life as unfavourable birth outcomes. Evidence indicates that neighbourhood socioeconomic circumstances influence health. However, studies looking into temporal trends in inequalities in birth outcomes including neighbourhood socioeconomic conditions are scarce. ...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2019-213162

    authors: Bertens LCM,Burgos Ochoa L,Van Ourti T,Steegers EAP,Been JV

    更新日期:2020-03-01 00:00:00

  • Contextual socioeconomic factors associated with childhood mortality in Nigeria: a multilevel analysis.

    abstract:BACKGROUND:Childhood mortality is a well-known public health issue, particularly in the low and middle income countries. The overarching aim of this study was to examine whether neighbourhood socioeconomic disadvantage is associated with childhood mortality beyond individual-level measures of socioeconomic status in Ni...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2015-205457

    authors: Adekanmbi VT,Kandala NB,Stranges S,Uthman OA

    更新日期:2015-11-01 00:00:00

  • Childhood household dysfunction, school performance and psychiatric care utilisation in young adults: a register study of 96 399 individuals in Stockholm County.

    abstract:BACKGROUND:Exposure to childhood household dysfunction increases the risk of psychiatric morbidity. Although school performance also has been linked with psychiatric morbidity, limited research has considered school performance as a mediating factor. To address this gap in the literature, the current register study exa...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2015-206329

    authors: Björkenstam E,Dalman C,Vinnerljung B,Weitoft GR,Walder DJ,Burström B

    更新日期:2016-05-01 00:00:00

  • Own education, current conditions, parental material circumstances, and risk of myocardial infarction in a former communist country.

    abstract:OBJECTIVE:To study the association between own education, adult and parental circumstances and the risk of myocardial infarction in a former communist country. DESIGN:Population based case-control study. SETTING:General population of five districts of the Czech Republic in the age group 25-64 years. PARTICIPANTS:Ran...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.54.2.91

    authors: Bobák M,Hertzman C,Skodová Z,Marmot M

    更新日期:2000-02-01 00:00:00

  • Workplace social capital and the onset of major depressive episode among workers in Japan: a 3-year prospective cohort study.

    abstract:BACKGROUND:This study examined the prospective association of workplace social capital (WSC) with major depressive episode (MDE) among Japanese employees. METHODS:A 3-year prospective cohort study was conducted among 1058 employees from a private think-tank company who participated in a baseline survey; after excludin...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2016-208561

    authors: Sakuraya A,Imamura K,Inoue A,Tsutsumi A,Shimazu A,Takahashi M,Totsuzaki T,Kawakami N

    更新日期:2017-06-01 00:00:00

  • Using the realist approach to unravel the complexity of health programmes: the evaluation of smoke-free school policies as a case study.

    abstract::Numerous commentaries plea for the use of methods that take into account complexity when evaluating health programmes. These commentaries provide compelling arguments on why evaluations of health programmes should not rely exclusively on methods that were designed for making universal claims about whether and to what ...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2020-214027

    authors: Schreuders M,Stronks K,Kunst AE

    更新日期:2021-01-01 00:00:00