Abstract:
:A unique chronic obstructive pulmonary disease (COPD), provisionally called "mustard lung", which occurs as a late complication of sulfur mustard (SM) exposure among SM-exposed Iranians, is presently poorly characterized. This investigation evaluates p53 immunoreactivity in bronchial epithelium of individuals with histories of tobacco use and/or SM exposure, as a tool to help define mustard lung. In this study, 68 COPD patients were segregated into two groups, 35 mustard-exposed patients (including 8 smokers) and 33 unexposed patients (including 16 smokers). Disease severity was assessed with pulmonary function tests. p53 protein in bronchial tissue obtained as biopsies was quantitated by immunostaining. Among nonsmokers, 41.2% of unexposed subjects and 14.8% of exposed subjects expressed p53. Among smokers, 25% of the unexposed group and 50% of the exposed group expressed the protein. Initial data trends suggest an additive contribution of SM exposure and smoking to p53 immunoreactivity. These results illustrate the use of p53 immunoreactivity in the characterization of COPD, including mustard lung.
journal_name
Mil Medjournal_title
Military medicineauthors
Ghanei M,Amiri S,Akbari H,Kosari F,Khalili AR,Alaeddini F,Aslani J,Giardina C,Haines DDdoi
10.7205/milmed.172.1.70subject
Has Abstractpub_date
2007-01-01 00:00:00pages
70-4issue
1eissn
0026-4075issn
1930-613Xjournal_volume
172pub_type
杂志文章abstract::Primary care providers are often the initial evaluators of soldiers presenting with acute eye complaints. It is crucial for these providers to master performing the basic eye examination with a systematic approach. Obtaining a thorough history is an important first step to the eye examination, but providers need to be...
journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/MILMED-D-15-00161
更新日期:2016-02-01 00:00:00
abstract::A functional capacity evaluation (FCE) evaluates the ability of an individual to perform activities related to employment. There is no FCE specific to the military population; therefore, a FCE for the military population (FCE-M) was developed to evaluate an injured service member's (SM) ability to return to duty. The ...
journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/MILMED-D-16-00072
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journal_title:Military medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1999-10-01 00:00:00
abstract::Hepatitis B (HBV) markers were studied in 710 subjects who had been on active duty for over 6 months in the Italian Armed Forces. The prevalence of HBsAg carriers was found to be 4.4%, while 31.6% of the subjects were positive for various HBV antibodies. A total of 137 subjects were vaccinated with an anti-HBV vaccine...
journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::Like all health care delivery systems, the U.S. Department of Defense Military Health System (MHS) strives to achieve top preventative care and population health outcomes for its members while operating at an efficient level and containing costs. The objective of this study is to understand the overall efficiency perf...
journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/MILMED-D-15-00309
更新日期:2016-08-01 00:00:00
abstract::The U.S. military health care system forms a vast network across thousands of miles to serve patients in the Pacific theater. The medical treatment facilities in the Pacific, however, act independently and do not effectively track patients in the air evacuation system. The patients and the tracking systems are so disc...
journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::This article presents the results of a survey distributed to military women within and outside the continental United States (CONUS and OCONUS) who had received prenatal care and delivered at one of six Army, Navy, or Air Force military facilities. This comparative descriptive study was undertaken to determine from th...
journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
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journal_title:Military medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1989-04-01 00:00:00
abstract::Gunshot wounds are the second leading cause of spinal cord injuries in developed countries, whereas in undeveloped and developing countries, this likelihood is much more. However, the weapon and injury characteristics are very different between those two groups of countries. The aim of this study was to review our exp...
journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/MILMED-D-14-00575
更新日期:2015-04-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:2001-02-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/MILMED-D-17-00010
更新日期:2017-09-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/MILMED-D-15-00019
更新日期:2016-02-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/milmed.169.2.155
更新日期:2004-02-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/milmed-d-00-2309
更新日期:2009-11-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/MILMED-D-15-00137
更新日期:2016-05-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
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journal_title:Military medicine
pub_type: 杂志文章
doi:
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journal_title:Military medicine
pub_type: 杂志文章
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更新日期:2017-03-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
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更新日期:2008-10-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
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更新日期:2020-11-21 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
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更新日期:2017-03-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:10.7205/milmed.172.6.647
更新日期:2007-06-01 00:00:00
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journal_title:Military medicine
pub_type: 杂志文章
doi:
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