Treatment of recurrent clear cell sarcoma of the kidney with brain metastasis.

abstract：OBJECTIVE:To investigate the effect of Helicobacter pylori eradication on platelet recovery in childhood chronic idiopathic thrombocytopenic purpura (ITP). PATIENTS AND METHODS:A multi-center randomized controlled trial was conducted. Patients aged 4-18 years, diagnosed with chronic ITP, defined by platelet count belo...

journal_title：Pediatric blood & cancer

authors： Treepongkaruna S,Sirachainan N,Kanjanapongkul S,Winaichatsak A,Sirithorn S,Sumritsopak R,Chuansumrit A

更新日期：2009-07-01 00:00:00

abstract：:The provision of tele-practice symptom management is often without the provision of evidence-based guidelines. Under the auspices of the Pediatric Oncology Group of Ontario, a nursing task force was established to appraise the evidence and develop guidelines. Promising new efforts to enhance symptom management through...

journal_title：Pediatric blood & cancer

authors： Tsimicalis A,De Courcy MJ,Di Monte B,Armstrong C,Bambury P,Constantin J,Dagelman B,Eves M,Jansen P,Honeyford L,Stregger D,Pediatric Oncology Group of Ontario.

更新日期：2011-10-01 00:00:00

abstract：:Juvenile xanthogranuloma (JXG) is a disorder of disputed origin thought to be related to the dermal/interstitial macrophage. A 5-year-old female presented with an aggressive systemic JXG that developed 5 months after the diagnosis of T-cell acute lymphoblastic leukemia (T-ALL). Examination of the T-cell receptor gamma...

journal_title：Pediatric blood & cancer

authors： Perez-Becker R,Szczepanowski M,Leuschner I,Janka G,Gokel M,Imschweiler T,Völpel S,Niehues T,Klapper W

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Sorafenib targets multiple pathways thought to be crucial in growth of plexiform neurofibroma (PN) in children with neurofibromatosis type 1 (NF1). Sorafenib has been tolerated with manageable toxicities in adults and children with refractory cancer. We conducted a separate study in this population. Monitori...

journal_title：Pediatric blood & cancer

authors： Kim A,Dombi E,Tepas K,Fox E,Martin S,Wolters P,Balis FM,Jayaprakash N,Turkbey B,Muradyan N,Choyke PL,Reddy A,Korf B,Widemann BC

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:We sought to determine the prevalence of abnormal pulmonary function tests (PFTs) in a cohort of children who had received whole lung irradiation (WLI) for treatment of metastatic disease. PROCEDURE:This was a retrospective (1988-2003) chart review that included all children treated at our institution with ...

journal_title：Pediatric blood & cancer

authors： Weiner DJ,Maity A,Carlson CA,Ginsberg JP

更新日期：2006-02-01 00:00:00

abstract：:A teenage boy presented with a CD30-positive anaplastic large cell lymphoma (ALCL) affecting his scapula and was successfully treated with chemotherapy. His clinical features and outcome were compared with other cases described in the literature. A further review of 11 ALCL cases with bony involvement treated in the U...

journal_title：Pediatric blood & cancer

authors： Ng A,Hobson R,Williams D,Morland B

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Pediatric nonrhabdomyosarcoma soft tissue sarcomas (NRSTS) may rarely occur in visceral tissues, and little is known about their clinical history. The present study retrospectively analyzed a group of patients prospectively registered in Italian pediatric protocols conducted between 1979 and 2004. METHODS:I...

journal_title：Pediatric blood & cancer

authors： Ferrari A,Magni C,Bergamaschi L,Cecchetto G,Alaggio R,Milano GM,Bertolini P,Basso E,Manzitti C,Di Martino M,Giurici N,Melchionda F,Cecinati V,Chiaravalli S,Affinita MC,Scagnellato A,Casanova M,Bisogno G

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Few studies have addressed the efficacy of palliative radiotherapy (RT) for pediatric osteosarcoma (OS), a disease generally considered to be radioresistant. We describe symptom relief, local control, and toxicity associated with palliative RT among children with OS. PROCEDURE:Patients diagnosed with OS at ...

journal_title：Pediatric blood & cancer

authors： Chen EL,Yoo CH,Gutkin PM,Merriott DJ,Avedian RS,Steffner RJ,Spunt SL,Pribnow AK,Million L,Donaldson SS,Hiniker SM

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Patients with relapsed or refractory Ewing sarcoma have a poor outcome with conventional therapies. Cytarabine decreases EWS/FLI1 protein levels in Ewing sarcoma cells and has demonstrated preclinical activity against Ewing sarcoma in vitro and in vivo. The purpose of this phase II clinical trial was to esti...

journal_title：Pediatric blood & cancer

authors： DuBois SG,Krailo MD,Lessnick SL,Smith R,Chen Z,Marina N,Grier HE,Stegmaier K,Children's Oncology Group.

更新日期：2009-03-01 00:00:00

abstract：:Opsoclonus, myoclonus, ataxia syndrome (OMA) is a severe neurologic disorder often associated with neuroblastoma. It is challenging to treat and can have long-term neurologic sequelae. Current recommended therapies include intravenous immunoglobulin, corticosteroids, rituximab, and chemotherapy (cyclophosphamide). We ...

journal_title：Pediatric blood & cancer

authors： Johnston DL,Murray S,Irwin MS,Doyle J,Schechter T

更新日期：2018-08-01 00:00:00

abstract：:Embryonal rhabdomyosarcoma (ERMS) is the most common childhood sarcoma and is a component of the familial pleuropulmonary blastoma (PPB)-predisposition syndrome. Using the PPB model, we hypothesized that DICER1 mutations would be found in familial and sporadic forms of ERMS. Blood samples from four children with famil...

journal_title：Pediatric blood & cancer

authors： Doros L,Yang J,Dehner L,Rossi CT,Skiver K,Jarzembowski JA,Messinger Y,Schultz KA,Williams G,André N,Hill DA

更新日期：2012-09-01 00:00:00

abstract：:As increasing numbers of childhood cancer patients are surviving, the long-term complications of the disease and its treatment have become ever more increasingly important. Reduced bone mineral density and increased fracture risk have been reported during and after treatment of children with cancer. The causes of oste...

journal_title：Pediatric blood & cancer

authors： van der Sluis IM,van den Heuvel-Eibrink MM

更新日期：2008-02-01 00:00:00

abstract：:We report two second malignant neoplasms (SMNs) of the parotid gland. Patient 1 was initially diagnosed with precursor B-cell lymphoblastic lymphoma of the scalp. Eight years after her initial diagnosis she presented with a small, painless mass in the region of her parotid gland. Patient 2 was diagnosed with pre-B-cel...

journal_title：Pediatric blood & cancer

authors： Savelli SL,Klopfenstein KJ,Termuhlen AM

更新日期：2005-12-01 00:00:00

abstract：:Imatinib can be safely discontinued in adults with chronic myeloid leukemia (CML) where there is a prolonged complete molecular response (CMR). No data are available in the pediatric population. Six children with CML discontinued imatinib by themselves. Only three of them were in CMR but for <2 years. A significant in...

journal_title：Pediatric blood & cancer

authors： Millot F,Claviez A,Leverger G,Corbaciglu S,Groll AH,Suttorp M

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Abandonment of treatment is one of the toughest challenges to deal with in pediatric oncology. It leads to unnecessary mortality and morbidity in patients from low- and middle-income countries. PROCEDURE:The objective of our retrospective study was to determine the prevalence and predictors for abandonment ...

journal_title：Pediatric blood & cancer

authors： Siddiqui DE,Ashraf MS,Iftikhar S,Belgaumi AF

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Langerhans cell histiocytosis (LCH) is a rare proliferative disorder of pathological Langerhans cells, for which the aetiology and pathogenesis remain largely unknown. PROCEDURE:Information on the 101 children with LCH registered with the population-based Manchester Children's Tumour Registry (MCTR) between...

journal_title：Pediatric blood & cancer

authors： Alston RD,Tatevossian RG,McNally RJ,Kelsey A,Birch JM,Eden TO

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Based on the presumed clinical similarity between the two most severe sickle cell disease (SCD) genotypes, hemoglobin (Hb) Sβ0 thalassemia and HbSS, randomized controlled trials (RCTs) have included both genotypes. Our group has demonstrated that healthcare providers inadequately distinguish the two diagnose...

journal_title：Pediatric blood & cancer

authors： Day ME,Rodeghier M,DeBaun MR

更新日期：2018-11-01 00:00:00

abstract：:A 4(3/4)-year-old male with Down syndrome (DS) presented with unsteady gait and fatigue. Neuroimaging revealed a cerebellar mass with concomitant obstructive hydrocephalus and additional metastatic lesions. He was successfully treated and is still in complete remission 5 years from diagnosis. The present case illustra...

journal_title：Pediatric blood & cancer

authors： Benesch M,Moser A,Sovinz P,Lackner H,Schwinger W,Eder H,Urban C

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Patients with Langerhans cell histiocytosis (LCH) may develop neurodegeneration and significant CNS sequelae, affecting a significant proportion of the patients. We here aimed to investigate the neuropsychological consequences in more detail. METHODS:Using an extensive neuropsychological test battery, we ev...

journal_title：Pediatric blood & cancer

authors： Van't Hooft I,Gavhed D,Laurencikas E,Henter JI

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Numerous recent reports have described the use of recombinant factor VIIa (rFVIIa) in non-hemophilia bleeding situations for achievement of hemostasis. However, its use in clinical situations other than hemophilia patients with inhibitors has been complicated by some reports of thrombotic events. rFVIIa has ...

journal_title：Pediatric blood & cancer

authors： Puetz J,Darling G,Brabec P,Blatny J,Mathew P

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Sorafenib is an inhibitor of multiple kinases (e.g., VEGF receptors, PDGFR, FLT3, RET, BRAF, KIT) and is approved by FDA for treatment of two adult cancers. The activity of sorafenib was evaluated against the PPTP's in vitro and in vivo panels. PROCEDURES:Sorafenib was evaluated against the PPTP in vitro pa...

journal_title：Pediatric blood & cancer

authors： Keir ST,Maris JM,Lock R,Kolb EA,Gorlick R,Carol H,Morton CL,Reynolds CP,Kang MH,Watkins A,Houghton PJ,Smith MA

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess glomerular and tubular renal function after HSCT in children in a prospective trial. METHODS:Renal function was assessed prospectively before HSCT (on day -10), on days +30, +100, and at least 6 months after transplantation in 34 patients (21 females/13 males) with a mean...

journal_title：Pediatric blood & cancer

authors： Hazar V,Gungor O,Guven AG,Aydin F,Akbas H,Gungor F,Tezcan G,Akman S,Yesilipek A

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Patients with sickle cell anemia (SCA) experience a broad range of psychiatric disorders, placing them at risk for more complicated and longer hospitalizations for vaso-occlusive crises (VOC). The current study examined the frequency of psychiatric disorders in SCA patients (ages birth to 20 years) admitted ...

journal_title：Pediatric blood & cancer

authors： Myrvik MP,Campbell AD,Davis MM,Butcher JL

更新日期：2012-02-01 00:00:00

abstract：:Obesity is increasing in prevalence in the United States with over 65% of adults considered overweight and 16% of children with BMI > 95 percentile. The heritability of obesity is estimated between 40% and 70%, but the genetics of obesity for most individuals are complex and involve the interaction of multiple genes a...

journal_title：Pediatric blood & cancer

authors： Chung WK

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Primary stroke prevention programmes for children with sickle cell disease (SCD) have been shown to be feasible interventions in resource-poor countries. Different hydroxyurea (HU) regimens have been utilised in ameliorating the severity of SCD. OBJECTIVE:To determine the long-term outcomes of the stroke pr...

journal_title：Pediatric blood & cancer

authors： Lagunju IA,Labaeka A,Ibeh JN,Orimadegun AE,Brown BJ,Sodeinde OO

更新日期：2021-02-01 00:00:00

abstract：:High dose acetaminophen (HDAC) with N-acetylcysteine (NAC) has been effective in adults with advanced malignancies. We report HDAC with NAC in a child with progressive hepatoblastoma, confirmed at biopsy of an unresectable hepatic mass. Alpha-fetoprotein (AFP) increased despite four courses of doxorubicin and one cour...

journal_title：Pediatric blood & cancer

authors： Kobrinsky NL,Sjolander DE,Goldenberg JA,Ortmeier TC

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:A feature often seen in adolescent patients with cancer is a lengthy symptom interval, especially in comparison with children. It has been suggested that inadequate awareness of cancer risk among adolescents may play an important role in this study. METHODS:The Società Italiana Adolescenti con Malattie Onco...

journal_title：Pediatric blood & cancer

authors： Magni C,Segrè C,Finzi C,Veneroni L,Clerici CA,Massimino M,Casanova M,Martinella V,Chiaravalli S,Ricci A,Biondi A,Ferrari A

更新日期：2016-08-01 00:00:00

abstract：:Neuroblastoma is the most common extracranial solid tumor of childhood, and the outcomes for children with high-risk and relapsed disease remain poor. However, new international strategies for risk stratification and for treatment based on novel tumor targets and including immunotherapy are being employed in attempts ...

journal_title：Pediatric blood & cancer

authors： Zage PE,Louis CU,Cohn SL

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Compared with healthy children, pediatric oncology patients have impaired sleep and engage in less physical activity (PA). Socioeconomic status (SES) may be one determinant of PA and sleep among pediatric oncology patients. PROCEDURE:Between November 12, 2009 and March 27, 2013, 50 pediatric oncology patien...

journal_title：Pediatric blood & cancer

authors： Orsey AD,Wakefield DB

更新日期：2016-11-01 00:00:00

abstract：:The BRAF V600E missense mutation is known to be present in a subset of central nervous system tumors. We report a patient with a BRAF V600E mutated pilomyxoid astrocytoma who failed multiple conventional chemotherapy regimens. Treatment with vemurafenib, a molecularly targeted therapy against the mutant BRAF V600E kin...

journal_title：Pediatric blood & cancer

authors： Skrypek M,Foreman N,Guillaume D,Moertel C

更新日期：2014-11-01 00:00:00