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Small molecule signaling in Caenorhabditis elegans.

Abstract：

:Whereas the C. elegans genome was sequenced many years ago, the role of small molecule signals in its biology is still poorly understood. A recent publication reports the identification of two steroidal signaling molecules that regulate C. elegans reproductive development and dauer diapause via the nuclear receptor DAF-12. The two compounds, named dafachronic acids, represent the first endogenous ligands identified for any of the 284 nuclear receptors in C. elegans.

journal_name

ACS Chem Biol

journal_title

ACS chemical biology

authors

Schroeder FC

doi

10.1021/cb600173t

subject

Has Abstract

pub_date

2006-05-23 00:00:00

pages

198-200

issue

4

eissn

1554-8929

issn

1554-8937

journal_volume

1

pub_type

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