当前位置： SCI文献检索 > ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY期刊下所有文献 > The effects of lindane poisoning on N-acetyldopamine and N-acetyl 5-hydroxytryptamine concentrations in the brain of Locusta migratoria L.

The effects of lindane poisoning on N-acetyldopamine and N-acetyl 5-hydroxytryptamine concentrations in the brain of Locusta migratoria L.

Abstract：

:High-performance liquid chromatography with electrochemical detection was used to measure N-acetyldopamine and N-acetyl 5-hydroxytryptamine in the cerebral ganglia of the African migratory locust, Locusta migratoria (fifth instar) exposed to lindane, a chlorinated insecticide. Locusts were poisoned by this insecticide in order to assess the effects of this neuroactive compound on these acetylated metabolites levels. Relatively low concentrations of N-acetyldopamine were observed in the cerebral ganglia. Incubation of ganglia resulted in increased concentrations of N-acetyldopamine and N-acetyl 5-hydroxytryptamine. Lindane significantly reduces N-acetyldopamine and N-acetyl 5-hydroxytryptamine levels in the cerebral ganglia. These results can be correlated with a decrease in N-acetyltransferase activity.

journal_name

Ecotoxicol Environ Saf

journal_title

Ecotoxicology and environmental safety

authors

Moreteau B,Chaminade N

doi

10.1016/0147-6513(90)90050-f

subject

Has Abstract

pub_date

1990-08-01 00:00:00

pages

115-20

issue

1

eissn

0147-6513

issn

1090-2414

pii

0147-6513(90)90050-F

journal_volume

20

pub_type

杂志文章

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