[Pten gene expression in the endometrial mucosa].

Abstract:

:The opinions about the causes of the endometrial carcinoma have changed since 1995, due to molecular biology progress. The findings concerning the recently discovered suppressor PTEN gene localized on the chromosome 10 -10q23.3, the product of which is a specific phosphatase are especially valuable. The loss of the gene function is directly linked with the genesis and progression of endometrial carcinoma, as well as cancers of other tissues and organs, including thyroid, breast, ovary, prostate or skin. Immunohistochemical studies with the use of the 6H2.1 antibody directed against the protein coded by the PTEN gene indicate that the protein cannot be found in more than half of the patients with endometrial carcinoma and its precursor--EIN. Mutations of the PTEN gene have also been detected in many young women with normal microscopic structure of the endometrial mucosa. Thus, a test for the absence of the PTEN gene product in the endometrial cells may be used for precise identification of early stages of carcinogenesis.

journal_name

Ginekol Pol

journal_title

Ginekologia polska

authors

Bakiewicz A,Goździk J,Sporny S

subject

Has Abstract

pub_date

2006-04-01 00:00:00

pages

323-9

issue

4

eissn

0017-0011

issn

2543-6767

journal_volume

77

pub_type

杂志文章,评审
  • [The dually perfused human placenta by Schneider method modified Miller. II. Changes of arterial and venous fetal blood pressure].

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    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Łopucki M,Szymczyk G,Polak G,Rogowska W,Wiktor H,Kotarski J

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  • The incidence of cervical intraepithelial neoplasia in a population of pregnant women with an abnormal cytology.

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    authors: Pruski D,Malkowska-Walczak B,Paluszkiewicz A,Kędzia W

    更新日期:2017-01-01 00:00:00

  • Ruptured ectopic pregnancy mimicking acute pancreatitis.

    abstract:INTRODUCTION:Ectopic pregnancy may lead to massive haemorrhage, infertility or death. Prompt diagnosis and treatment are crucial to save patients who would otherwise die. Serum amylase and lipase measurements are known biochemical markers of pancreatic inflammation and a recognized finding that may help diagnose acute ...

    journal_title:Ginekologia polska

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    doi:

    authors: Mitura K,Romanczuk M

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  • [Changes in levels of chorionic gonadotrophin (hCG) and its subunit alpha and beta in pregnancy complicated by diabetes (GDM)].

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    doi:

    authors: Olszewski J,Szczurowicz A,Wójcikowski C

    更新日期:1995-02-01 00:00:00

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    abstract::The results of peritoneal cytology obtained during primary surgery for stage I ovarian cancer and "second look" operations was assessed. Positive peritoneal smears were found in 10.7% of patients, while neoplastic cells were present in peritoneal fluid in 32.5% of cases. Of 144 patients undergoing "second look" surger...

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    doi:

    authors: Emerich J,Konefka T,Dudziak M,Sobol A

    更新日期:1997-02-01 00:00:00

  • [Ways of delivery after cesarean section].

    abstract:OBJECTIVE:To analyse deliveries after a previous cesarean section. STUDY DESIGN:The way of birth of 262 patients between 1993-1995 in the Ist Department of Obstetrics and Gynaecology of Warsaw University Hospital was analysed. Material was divided into two groups: an elective cesarean section operation was performed o...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Szachułowicz J,Karwan-Płońska A,Balcer A,Donarska-Suchońska B,Mielczarek W

    更新日期:1999-09-01 00:00:00

  • [The respiratory system in pregnancy].

    abstract::A survey throughout world literary output concerning physiology of respiratory system in pregnancy was made in this work. Metabolical changes caused by the increase of progesterone and other substances concentration and changes of the mechanics of ventilation connected by diaphragm raising caused by the growing uterus...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Buchacz P,Poreba R,Kozielski J

    更新日期:1995-06-01 00:00:00

  • [Myomas and pregnancy--obstetrics dilemma of the next decade?].

    abstract:OBJECTIVES:This article describes the most frequent reasons, complications and appropriate treatment of pregnancy with uterine myomas and pregnancy after the myomectomy. MATERIALS AND METHODS:It is the analysis of pregnancies and deliveries of 24 women hospitalised in Medical Academy of Gdańsk. RESULTS:The typical co...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Kulikowska-Ciecielag K,Płoszyński A,Damdinsuren A,Leszczyńska K,Mielnik J

    更新日期:2002-04-01 00:00:00

  • [The influence of twenty years of Rh (D) factor incompatibility immunoprophylaxis on reducing the occurrence of hemolytic disease in newborns].

    abstract::The study presents the frequency of occurrence of newborn haemolitic disease caused by Rh (D) system incompatibility in the years 1980-1999. Serological incompatibility prophylaxis was introduced in 1980. Routine use of anti-D immunoglobulin has led to a significant reduction in the number of newborns with haemalitic ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Suchocki S,Bojarska J,Bojarski M,Poleszczuk J

    更新日期:2000-08-01 00:00:00

  • [Evaluation of selected parameters of lymphocyte activity in umbilical blood. I. Natural cytotoxicity].

    abstract::Natural cytotoxic activity in the umbilical blood was estimated in 52 healthy newborns. Mononuclear cells were isolated from the umbilical blood using Boym's method. The mean natural cell cytotoxicity in the examined group was 7.05 +/- 0.9 (SD). ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Kamiński P,Majewski S,Radomska M,Skopińska-Rózewska E,Szymański R,Marianowski L

    更新日期:1996-02-01 00:00:00

  • [Disseminated peritoneal leiomyomatosis--case report and literature review].

    abstract::Leiomyomatosis peritonealis disseminata(LPD) is a rare smooth muscle pathology, characterized by the presence of multiple tumors in peritoneal cavity mimicking a malignant process with metastases. The diagnosis may be difficult in some cases as the results of ultrasonography and CT imaging may suggest malignancy. The ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Sobiczewski P,Bidziński M,Radziszewski J,Panek G,Olszewski W,Tacikowska M

    更新日期:2004-03-01 00:00:00

  • [Agenesis of the ductus venosus--an irrelevant anomaly or a severe clinical problem?].

    abstract:BACKGROUND:Ductus venosus is the fetal blood vessel connecting the abdominal portion of the umbilical vein with the inferior vena cava. Numerous studies have confirmed the important role of this vessel in fetal circulation. There are, however cases when finding the ductus venosus during an ultrasound examination is imp...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.17772/gp/1623

    authors: Cnota W,Włoch A,Czuba B,Wójtowicz D,Sodowski K

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  • [Pregnancy in women with multiple sclerosis (MS): a report of 2 cases].

    abstract::We report two cases of pregnancy in patients with multiple sclerosis. Both of women were primigravidas. In both cases pregnancy were ended by cesarean section: in first case due to obstetric indications, in second due to neurological indications. Our experience and a review of current literature are presented. ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Starnawski M,Olszewski J,Milczek T,Klasa-Mazurkiewicz D

    更新日期:1998-12-01 00:00:00

  • The clinical evaluation of internal iliac arteries balloon occlusion for placenta accreta spectrum.

    abstract:OBJECTIVES:To evaluate the balloon occlusion of the internal iliac arteries during a caesarean section in the group of patients with placenta accreta spectrum. MATERIAL AND METHODS:We analysed 29 pregnant women with placenta accreta spectrum. The study group consisted of 15 patients, who underwent a caesarean delivery...

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    pub_type: 杂志文章

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    authors: Rosner-Tenerowicz A,Fuchs T,Pomorski M,Sliwa J,Zimmer-Stelmach A,Zimmer M

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  • Survivin--prognostic tumor biomarker in human neoplasms--review.

    abstract::Accurate diagnosis and proper monitoring of cancer patients remain important obstacles for successful cancer treatment. The search for cancer biomarkers is carried out in order to quickly identify tumor cells and predict treatment response, ultimately leading to a favorable therapeutic outcome. One such prognostic mar...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Waligórska-Stachura J,Jankowska A,Waśko R,Liebert W,Biczysko M,Czarnywojtek A,Baszko-Błaszyk D,Shimek V,Ruchała M

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  • [Activin A as a possible marker for hypoxia and intraventricular haemorrhage in newborns].

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    authors: Fiala M,Baumert M,Walencka Z

    更新日期:2009-06-01 00:00:00

  • [Results of clomiphene citrate ovarian stimulation vs laparoscopic electrocoagulation of the ovaries in infertile women with PCOS].

    abstract:OBJECTIVE:To assess the results of clomiphene citrate ovarian stimulation vs laparoscopic electrocoagulation of the ovaries in infertile women with PCOS. DESIGN:47 women with PCOS were included into the study. 25 of them had ovarian stimulation using clomiphene citrate (100 mg for 5 consecutive days, during 6 cycle) a...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Grzechocińska B,Fracki S,Marianowski L

    更新日期:2000-09-01 00:00:00

  • [Cesarean section for the second twin during the course of delivering twins].

    abstract::We have analysed 6 cases of twin pregnancies with vertex presentation of the first foetus. In this cases after delivery of the first twin by vaginal route caesarean, section was made. Caesarean section of the second twin was made because of: transversal presentation with fetal distress syndrom (four cases), umbilical ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Markowska A,Seremak-Mrozikiewicz A,Malewski Z,Drews K,Słomko Z

    更新日期:2000-11-01 00:00:00

  • [Cesarean section by the Misgav Ladach+ with the abdominal opening surgery by the Joel Cohen method].

    abstract::The purpose of this study was to compare 90 Misgav-Ladach cesarean section by the Joel-Cohen method with 45 others with Pfannenstiel incision. The Misgav-Ladach technique involves the Joel-Cohen method, that is a superficial transverse cut in the cutis, a small midline incision in the fascia, then blunt preparation of...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Zienkowicz Z,Suchocki S,Sleboda H,Bojarski M

    更新日期:2000-04-01 00:00:00

  • [Diagnostic micro-laparoscopy in gynecology].

    abstract::Diagnostic microlaparoscopy was performed on 30 patients aged 17-41. Indications++ for these procedures were: sterility (17), tumor of the ovary (5), endometriosis (3), uterine myoma (2), pelvic pain syndrome++ (1), carcinoma of the ovary--second look procedures (1), operative hysteroscopy (1). During these procedures...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Obrzut B,Skret A,Kluz T

    更新日期:1999-08-01 00:00:00

  • [The management of subarachnoid hemorrhage in pregnancy].

    abstract::Subarachnoid haemorrhage (SAH) from an intracranial aneurysm or arteriovenous malformation is a grave complication of pregnancy. Authors critically analyzed 12 cases of verified SAH during pregnancy from an 11 identified and 1 unidentified cerebral vascular malformation. Aneurysms were responsible for SAH in 7, and ar...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Zukiel R,Jankowski R,Tokarz F

    更新日期:1992-04-01 00:00:00

  • [Microheterogeneity of two acute phase proteins in patients with ovarian carcinoma].

    abstract::Concentrations of two acute phase proteins: alpha 2-macroglobulin (alpha 2M) and transferrin (Tf) as well as glycosylation profiles of alpha 2M and Tf were studied in sera samples from 13 patients suffering from ovarian cancer. In the observed group of patients with ovarian cancer in whom the progression of disease wa...

    journal_title:Ginekologia polska

    pub_type: 临床试验,杂志文章

    doi:

    authors: Kanikowska D,Madry R,Drózdz-Górska J,Sobieska M,Markowska J,Wiktorowicz K

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  • [Cytogenetic analysis in couples with spontaneous abortions].

    abstract::Cytogenetic studies were performed in 129 couples with the history of recurrent spontaneous miscarriages. In 8 couples (6.2%) chromosome aberrations were found The most frequent aberrations were reciprocal translocations (in 6 couples). Pericentric inversion of chromosome 9 was detected in 3 couples (2.3%) while the c...

    journal_title:Ginekologia polska

    pub_type: 临床试验,杂志文章

    doi:

    authors: Sasiadek M,Haus O,Lukasik-Majchrowska M,Slezak R,Paprocka-Borowicz M,Busza H,Plewa R,Bułło A,Jagielski J

    更新日期:1997-05-01 00:00:00

  • [Leiomyoma of small intestine in patient treated for ovarian tumor].

    abstract::Small intestinal tumors are relatively rare, and notoriously difficult to diagnose. In our case 64 years old female was operated because suspicion of ovarian tumor. The complained on recurrent gastrointestinal bleeding. An arteriogram of superior mesenteric artery revealed arteriovenous malformation in the distal part...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Czubalski A,Barwijuk A,Dziag R

    更新日期:1997-07-01 00:00:00

  • [The influence of paternal lymphocytes immunization on percentage of peripheral blood CD16+/CD56+ cells in women with primary recurrent spontaneous abortion].

    abstract:OBJECTIVES:Paternal lymphocytes immunization has been proposed for several years as an efficient treatment for unexplained Recurrent Spontaneous Abortion (RSA), however precise mechanism that underline the benefits of this immunotherapy is still unclear. DESIGN:The aim was to study the influence of paternal lymphocyte...

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    doi:

    authors: Szpakowski A,Malinowski A,Zeman K,Wilczyński J,Kolasa D,Nowak M,Władziński J,Kamiński T,Szpakowski M

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  • [Serum levels of CA-125 antigen during the first trimester of pregnancy complications and the risk of miscarriage].

    abstract:BACKGROUND:The ultrasound, serum beta-HCG and progesterone titres are widely used to assess the risk of miscarriage at the early stages of pregnancy. Though very useful, they are not considered as satisfactorily accurate predictors of imminent abortion during the first three months of pregnancy. AIM OF STUDY:Prospecti...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Fiegler P,Kamiński K,Wegrzyn P

    更新日期:2003-05-01 00:00:00

  • [Artificial abortion in women with heart defects].

    abstract::Out of 4676 women administered abortions between 1965-1969, 20 (.42%) were performed for medical indications related to heart defects. Pregnancy was terminated between the 6th-12th week. Therapeutic abortion itself can be hazardous to the health in these cases due to the state of the circulatory system. The most freq...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Piechowiak Z,Mazurowa A,Kieszkiewicz J

    更新日期:1971-01-01 00:00:00

  • [Sexual activity among young women. Medical and legal aspects].

    abstract:BACKGROUND:Proper age of sexual initiation remains a topical issue in developmental sexology and gynecology Premature sexual début is a risk factor for sexually transmitted diseases (STD) and their consequences: unplanned pregnancy and emotional stress. Consequences of risky sexual behavior (young age of sexual initiat...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Jarzabek-Bielecka G,Durda M,Sowińska-Przepiera E,Kaczmarek M,Kedzia W

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  • [The impact of premature rupture of membranes (PROM) on neonatal outcome].

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