Abstract:
:The opinions about the causes of the endometrial carcinoma have changed since 1995, due to molecular biology progress. The findings concerning the recently discovered suppressor PTEN gene localized on the chromosome 10 -10q23.3, the product of which is a specific phosphatase are especially valuable. The loss of the gene function is directly linked with the genesis and progression of endometrial carcinoma, as well as cancers of other tissues and organs, including thyroid, breast, ovary, prostate or skin. Immunohistochemical studies with the use of the 6H2.1 antibody directed against the protein coded by the PTEN gene indicate that the protein cannot be found in more than half of the patients with endometrial carcinoma and its precursor--EIN. Mutations of the PTEN gene have also been detected in many young women with normal microscopic structure of the endometrial mucosa. Thus, a test for the absence of the PTEN gene product in the endometrial cells may be used for precise identification of early stages of carcinogenesis.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Bakiewicz A,Goździk J,Sporny Ssubject
Has Abstractpub_date
2006-04-01 00:00:00pages
323-9issue
4eissn
0017-0011issn
2543-6767journal_volume
77pub_type
杂志文章,评审abstract::The study was carried out on 7 human placental cotyledons. Placental perfusions performed by Schneider method modified by Miller were conducted for 180 min. assessment of arterial and venous pressure in fetal blood was performed. There were no statistically significant differences between obtained values of perfusion ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVES:To assess the incidence of cervical intraepithelial neoplasia - SIL and cervical cancer in a population of pregnant women with an abnormal cytology. MATERIAL AND METHODS:In pregnant women with abnormal cytology results according to The Bethesda System, a verifying diagnostics was carried out, including colp...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.a2017.0004
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:Ectopic pregnancy may lead to massive haemorrhage, infertility or death. Prompt diagnosis and treatment are crucial to save patients who would otherwise die. Serum amylase and lipase measurements are known biochemical markers of pancreatic inflammation and a recognized finding that may help diagnose acute ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
abstract::The aim of the study was estimation of endocrinological function of placenta in pregnancy complicated by GDM. The study were performed on a group 13 women with GDM and 14 women in normal pregnancy. All women with GDM were treat by diet and intensive insulinotherapy with self monitoring levels of glucose. In women with...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1995-02-01 00:00:00
abstract::The results of peritoneal cytology obtained during primary surgery for stage I ovarian cancer and "second look" operations was assessed. Positive peritoneal smears were found in 10.7% of patients, while neoplastic cells were present in peritoneal fluid in 32.5% of cases. Of 144 patients undergoing "second look" surger...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:To analyse deliveries after a previous cesarean section. STUDY DESIGN:The way of birth of 262 patients between 1993-1995 in the Ist Department of Obstetrics and Gynaecology of Warsaw University Hospital was analysed. Material was divided into two groups: an elective cesarean section operation was performed o...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::A survey throughout world literary output concerning physiology of respiratory system in pregnancy was made in this work. Metabolical changes caused by the increase of progesterone and other substances concentration and changes of the mechanics of ventilation connected by diaphragm raising caused by the growing uterus...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:1995-06-01 00:00:00
abstract:OBJECTIVES:This article describes the most frequent reasons, complications and appropriate treatment of pregnancy with uterine myomas and pregnancy after the myomectomy. MATERIALS AND METHODS:It is the analysis of pregnancies and deliveries of 24 women hospitalised in Medical Academy of Gdańsk. RESULTS:The typical co...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
abstract::The study presents the frequency of occurrence of newborn haemolitic disease caused by Rh (D) system incompatibility in the years 1980-1999. Serological incompatibility prophylaxis was introduced in 1980. Routine use of anti-D immunoglobulin has led to a significant reduction in the number of newborns with haemalitic ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2000-08-01 00:00:00
abstract::Natural cytotoxic activity in the umbilical blood was estimated in 52 healthy newborns. Mononuclear cells were isolated from the umbilical blood using Boym's method. The mean natural cell cytotoxicity in the examined group was 7.05 +/- 0.9 (SD). ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
abstract::Leiomyomatosis peritonealis disseminata(LPD) is a rare smooth muscle pathology, characterized by the presence of multiple tumors in peritoneal cavity mimicking a malignant process with metastases. The diagnosis may be difficult in some cases as the results of ultrasonography and CT imaging may suggest malignancy. The ...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:Ductus venosus is the fetal blood vessel connecting the abdominal portion of the umbilical vein with the inferior vena cava. Numerous studies have confirmed the important role of this vessel in fetal circulation. There are, however cases when finding the ductus venosus during an ultrasound examination is imp...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.17772/gp/1623
更新日期:2013-08-01 00:00:00
abstract::We report two cases of pregnancy in patients with multiple sclerosis. Both of women were primigravidas. In both cases pregnancy were ended by cesarean section: in first case due to obstetric indications, in second due to neurological indications. Our experience and a review of current literature are presented. ...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVES:To evaluate the balloon occlusion of the internal iliac arteries during a caesarean section in the group of patients with placenta accreta spectrum. MATERIAL AND METHODS:We analysed 29 pregnant women with placenta accreta spectrum. The study group consisted of 15 patients, who underwent a caesarean delivery...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:10.5603/GP.a2020.0180
更新日期:2021-01-15 00:00:00
abstract::Accurate diagnosis and proper monitoring of cancer patients remain important obstacles for successful cancer treatment. The search for cancer biomarkers is carried out in order to quickly identify tumor cells and predict treatment response, ultimately leading to a favorable therapeutic outcome. One such prognostic mar...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2012-07-01 00:00:00
abstract::The article presents general information about activin A, a glycoprotein that belongs to the transforming growth factor beta superfamily. Structure, mechanism and role of activin as a possible marker of hypoxia and intraventricular haemorrhage were described. ...
journal_title:Ginekologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:To assess the results of clomiphene citrate ovarian stimulation vs laparoscopic electrocoagulation of the ovaries in infertile women with PCOS. DESIGN:47 women with PCOS were included into the study. 25 of them had ovarian stimulation using clomiphene citrate (100 mg for 5 consecutive days, during 6 cycle) a...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::We have analysed 6 cases of twin pregnancies with vertex presentation of the first foetus. In this cases after delivery of the first twin by vaginal route caesarean, section was made. Caesarean section of the second twin was made because of: transversal presentation with fetal distress syndrom (four cases), umbilical ...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract::The purpose of this study was to compare 90 Misgav-Ladach cesarean section by the Joel-Cohen method with 45 others with Pfannenstiel incision. The Misgav-Ladach technique involves the Joel-Cohen method, that is a superficial transverse cut in the cutis, a small midline incision in the fascia, then blunt preparation of...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract::Diagnostic microlaparoscopy was performed on 30 patients aged 17-41. Indications++ for these procedures were: sterility (17), tumor of the ovary (5), endometriosis (3), uterine myoma (2), pelvic pain syndrome++ (1), carcinoma of the ovary--second look procedures (1), operative hysteroscopy (1). During these procedures...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1999-08-01 00:00:00
abstract::Subarachnoid haemorrhage (SAH) from an intracranial aneurysm or arteriovenous malformation is a grave complication of pregnancy. Authors critically analyzed 12 cases of verified SAH during pregnancy from an 11 identified and 1 unidentified cerebral vascular malformation. Aneurysms were responsible for SAH in 7, and ar...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::Concentrations of two acute phase proteins: alpha 2-macroglobulin (alpha 2M) and transferrin (Tf) as well as glycosylation profiles of alpha 2M and Tf were studied in sera samples from 13 patients suffering from ovarian cancer. In the observed group of patients with ovarian cancer in whom the progression of disease wa...
journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Cytogenetic studies were performed in 129 couples with the history of recurrent spontaneous miscarriages. In 8 couples (6.2%) chromosome aberrations were found The most frequent aberrations were reciprocal translocations (in 6 couples). Pericentric inversion of chromosome 9 was detected in 3 couples (2.3%) while the c...
journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract::Small intestinal tumors are relatively rare, and notoriously difficult to diagnose. In our case 64 years old female was operated because suspicion of ovarian tumor. The complained on recurrent gastrointestinal bleeding. An arteriogram of superior mesenteric artery revealed arteriovenous malformation in the distal part...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVES:Paternal lymphocytes immunization has been proposed for several years as an efficient treatment for unexplained Recurrent Spontaneous Abortion (RSA), however precise mechanism that underline the benefits of this immunotherapy is still unclear. DESIGN:The aim was to study the influence of paternal lymphocyte...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:The ultrasound, serum beta-HCG and progesterone titres are widely used to assess the risk of miscarriage at the early stages of pregnancy. Though very useful, they are not considered as satisfactorily accurate predictors of imminent abortion during the first three months of pregnancy. AIM OF STUDY:Prospecti...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract::Out of 4676 women administered abortions between 1965-1969, 20 (.42%) were performed for medical indications related to heart defects. Pregnancy was terminated between the 6th-12th week. Therapeutic abortion itself can be hazardous to the health in these cases due to the state of the circulatory system. The most freq...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:1971-01-01 00:00:00
abstract:BACKGROUND:Proper age of sexual initiation remains a topical issue in developmental sexology and gynecology Premature sexual début is a risk factor for sexually transmitted diseases (STD) and their consequences: unplanned pregnancy and emotional stress. Consequences of risky sexual behavior (young age of sexual initiat...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:The aim of the following study was to evaluate the impact of premature rupture of membranes (PROM) on neonatal outcome, particularly on the incidence of intrauterine infections (IUI). MATERIAL AND METHODS:The study included 428 newborns, born after PROM and hospitalized in the Department of Neonatology at Po...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Embryonal rhabdomyosarcoma in a form of a polyp of the uterine cervix occurs mainly in young women in their second decade of life. The characteristic microscopic features are: the submucosal cambium layer and the presence of rhabdomyoblasts in the stroma. So far the treatment has not been well defined and ra...
journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2011-11-01 00:00:00