Therapy-related acute myeloid leukemia in a child with Noonan syndrome and clonal duplication of the germline PTPN11 mutation.

abstract：:Chronic lymphocytic leukemia/lymphoma (CLL) is an extremely rare disease during childhood. We report a 16-year-old female who presented with lymphadenopathies and she was diagnosed as T cell lymphoblastic lymphoma. Her chemotherapy response was minimal and clinical findings were unusual. Therefore, her biopsy specimen...

journal_title：Pediatric blood & cancer

authors： Demir HA,Bayhan T,Üner A,Kurtulan O,Karakuş E,Emir S,Özyörük D,Ceylaner S

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Children with sickle cell disease (SCD) and abnormal transcranial Doppler (TCD) ultrasonography have a high risk of stroke, but this risk is greatly reduced when chronic transfusion therapy is administered. The change in TCD velocities during chronic transfusion therapy and rate and frequency of normalizatio...

journal_title：Pediatric blood & cancer

authors： Kwiatkowski JL,Yim E,Miller S,Adams RJ,STOP 2 Study Investigators.

更新日期：2011-05-01 00:00:00

abstract：:Most publications report the adverse (negative) health issues in childhood cancer survivors. Presenting information to the newly diagnosed patient in a positive manner is advocated, while noting that recurrence is the most likely adverse event. Re-analysis of population-based studies on life-threatening toxicities fro...

journal_title：Pediatric blood & cancer

authors： Fryer C

更新日期：2011-12-15 00:00:00

abstract：BACKGROUND:Various projects dedicated specifically to adolescents and young adults (AYA) with cancer have been developed in recent years. A critical aspect of such programs is the ability to demonstrate its value, and therefore how to measure desired outcomes. METHODS:A list of metrics to consider for demonstrating th...

journal_title：Pediatric blood & cancer

authors： Ferrari A,Silva M,Veneroni L,Magni C,Clerici CA,Meazza C,Terenziani M,Spreafico F,Chiaravalli S,Casanova M,Luksch R,Catania S,Schiavello E,Biassoni V,Podda M,Bergamaschi L,Puma N,Indini A,Proserpio T,Massimino M

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:We sought to determine the prevalence of abnormal pulmonary function tests (PFTs) in a cohort of children who had received whole lung irradiation (WLI) for treatment of metastatic disease. PROCEDURE:This was a retrospective (1988-2003) chart review that included all children treated at our institution with ...

journal_title：Pediatric blood & cancer

authors： Weiner DJ,Maity A,Carlson CA,Ginsberg JP

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Hepatic veno-occlusive disease (VOD) is one of the most serious complications in stem cell transplantation (SCT). Although plasma protein C activity decreases in VOD after SCT, the timeframe of plasma protein C activity decreases during SCT is not known. PROCEDURE:We examined levels of plasma protein C seri...

journal_title：Pediatric blood & cancer

authors： Iguchi A,Kobayashi R,Kaneda M,Kobayashi K

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Testicular germ cell tumors (T-GCTs) occur from infancy to adulthood, and are the most common solid tumor in adolescent and young adult males. Traditionally, pediatric T-GCTs were perceived as more indolent than adult T-GCTs. However, there are few studies comparing these groups and none that specifically ev...

journal_title：Pediatric blood & cancer

authors： Cost NG,Lubahn JD,Adibi M,Romman A,Wickiser JE,Raj GV,Sagalowsky AI,Margulis V

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:While adolescents and adults with sickle cell disease (SCD) have reported using religion to cope with SCD, there is no data examining religious coping in young children with SCD. The purpose of this qualitative study was to: (1) describe the types of religious coping used by children with SCD; (2) describe t...

journal_title：Pediatric blood & cancer

authors： Cotton S,Grossoehme D,McGrady ME

更新日期：2012-02-01 00:00:00

abstract：INTRODUCTION:Regret about loss is one of the most intense types of regret experienced in life. Little is known about the bereavement regret of parents whose child has died of cancer. Although knowledge about parents' experiences after their child's death is vital for supporting these families, parents' regret is mostly...

journal_title：Pediatric blood & cancer

authors： Sim CW,Heuse S,Weigel D,Kendel F

更新日期：2020-06-01 00:00:00

abstract：:Familial hemophagocytic lymphohistiocytosis (FHLH) is an autosomal recessive disorder of cytotoxic cell function that results in abnormal proliferation of benign lymphocytes and histiocytes in response to infectious stimuli. FHLH generally occurs in very young children, and typically presents with fever, cytopenias, c...

journal_title：Pediatric blood & cancer

authors： Beaty AD,Weller C,Levy B,Vogler C,Ferguson WS,Bicknese A,Knutsen AP

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Coping with end-stage pediatric cancer patients and the related bereavement is a challenge for all the caregivers involved. PROCEDURE:Forty-seven cancer patients who died in 2006 were assessed as concerns the main place of care in the end stage of their disease, their symptoms, the palliative treatments rec...

journal_title：Pediatric blood & cancer

authors： Beretta S,Polastri D,Clerici CA,Casanova M,Cefalo G,Ferrari A,Luksch R,Massimino M,Meazza C,Podda MG,Spreafico F,Terenziani M,Bellani FF

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To determine the safety, efficacy, and PK profile of intravenous busulfan (Bu) in the context of a Bu and cyclophosphamide (IVBuCy) preparative regimen in children undergoing allogeneic hematopoietic stem cell transplantation (HSCT). METHODS:Twenty-four children were enrolled in an open-label, multicenter tria...

journal_title：Pediatric blood & cancer

authors： Wall DA,Chan KW,Nieder ML,Hayashi RJ,Yeager AM,Kadota R,Przepiorka D,Mezzi K,Kletzel M,Pediatric Blood, Marrow Transplant Consortium.

更新日期：2010-02-01 00:00:00

abstract：:Myasthenia gravis is among the rare complications after allogeneic hematopoietic stem cell transplantation and is usually associated with chronic GVHD. Herein, we report a 2-year and 10 months of age female with Griscelli syndrome, who developed severe myasthenia gravis at post-transplant +22nd month and required resp...

journal_title：Pediatric blood & cancer

authors： Unal S,Sag E,Kuskonmaz B,Kesici S,Bayrakci B,Ayvaz DC,Tezcan I,Yalnızoglu D,Uckan D

更新日期：2014-05-01 00:00:00

abstract：:Essential thrombocythemia is a rare myleoproliferative disorder in pediatrics. This myleoproliferative disorder is characterized by excessive proliferation of megakaryocytes and sustained elevation of platelet count. Reactive thrombocytosis is a more common cause of elevated platelet counts among children. We describe...

journal_title：Pediatric blood & cancer

authors： Robins EB,Niazi M

更新日期：2008-04-01 00:00:00

abstract：INTRODUCTION:Major advances in the field of pediatric oncology have resulted from rigorous, prospective clinical oncology research trials. Optimizing access for all children and adolescents to clinical research trials is an important goal. Barriers to clinical trial enrollment are numerous, involving the health care sy...

journal_title：Pediatric blood & cancer

authors： Russo C,Stout L,House T,Santana VM

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:The Children's Oncology Group conducted a phase II trial of 21-day continuous infusion topotecan to determine the response rate in pediatric patients with recurrent or refractory malignant solid tumors. PROCEDURE:Patients with Ewing sarcoma family of tumors (ESFT), osteosarcoma (OS), soft tissue sarcomas (STS)...

journal_title：Pediatric blood & cancer

authors： Hawkins DS,Bradfield S,Whitlock JA,Krailo M,Franklin J,Blaney SM,Adamson PC,Reaman G

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The identification of tissue-specific differentially methylated regions (tDMRs) is key to our understanding of mammalian development. Research has indicated that tDMRs are aberrantly methylated in cancer and may affect the oncogenic process. PROCEDURE:We used the MassARRAY EpiTYPER system to determine the q...

journal_title：Pediatric blood & cancer

authors： Sugito K,Kawashima H,Uekusa S,Yoshizawa S,Hoshi R,Furuya T,Kaneda H,Hosoda T,Masuko T,Ohashi K,Ikeda T,Koshinaga T,Fujiwara K,Igarashi J,Ghosh S,Held WA,Nagase H

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:We sought to determine the risk of bacteremia in a cohort of outpatient febrile nonneutropenic pediatric oncology patients and to assess clinical characteristics that may influence decisions regarding empiric antibiotic therapy. PROCEDURE:A single institution retrospective cohort study was performed of outp...

journal_title：Pediatric blood & cancer

authors： Kelly MJ,Vivier PM,Panken TM,Schwartz CL

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Treatment with radiotherapy (RT) is associated with an increased risk of second malignant neoplasms (SMNs) in childhood cancer survivors; it is unclear how treatment with intensity-modulated radiation therapy (IMRT) impacts this risk. We provide the first report of SMN risk in a cohort of childhood cancer su...

journal_title：Pediatric blood & cancer

authors： Casey DL,Friedman DN,Moskowitz CS,Hilden PD,Sklar CA,Wexler LH,Wolden SL

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms have been implicated in childhood acute lymphoblastic leukemia (ALL) risk, but previously published studies were inconsistent and recent meta-analyses were not adequate. PROCEDURES:In a meta-analysis of 21 publications with 4,706 cas...

journal_title：Pediatric blood & cancer

authors： Yan J,Yin M,Dreyer ZE,Scheurer ME,Kamdar K,Wei Q,Okcu MF

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The use of carboplatin for the treatment of pediatric low grade gliomas (PLGG) is often limited by the development of carboplatin hypersensitivity. Reported rates of carboplatin hypersensitivity reactions vary between 6% and 32% in these patients. Here we report the frequency of carboplatin hypersensitivity ...

journal_title：Pediatric blood & cancer

authors： Dodgshun AJ,Hansford JR,Cole T,Choo S,Sullivan MJ

更新日期：2016-01-01 00:00:00

abstract：:Poikiloderma with neutropenia (PN) is a genodermatosis characterized by poikiloderma, permanent neutropenia, recurrent infections, nail abnormalities, and palmoplantar hyperkeratosis. We report the case of a Tunisian patient with PN. Skin lesions started from the face and spread to the extremities and trunk. Neutropen...

journal_title：Pediatric blood & cancer

authors： Sakka R,Mahjoub B,Kerkeni E,Werdani A,Boussoffara R,Ben Cheikh H,M'rad R,Sfar MT

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Knowledge about their past medical history is central for childhood cancer survivors to ensure informed decisions in their health management. Knowledge about information provision and information needs in this population is still scarce. We thus aimed to assess: (1) the information survivors reported to have...

journal_title：Pediatric blood & cancer

authors： Gianinazzi ME,Essig S,Rueegg CS,von der Weid NX,Brazzola P,Kuehni CE,Michel G,Swiss Paediatric Oncology Group (SPOG).

更新日期：2014-02-01 00:00:00

abstract：:Sickle cell disease (SCD) is an inherited red blood cell disorder that occurs worldwide and results in significant morbidity and mortality. In addition to affected children who are born in the US, an increasing number of children with SCD are migrating to the US with their families or through international adoption. C...

journal_title：Pediatric blood & cancer

authors： Thornburg CD,Ware RE

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:Research using banked tissue is key to advancing risk-stratification and treatment of children with cancer. Knowledge of parental attitudes to ethical issues arising in tissue banking is very limited but essential in obtaining respectful consent. METHODS:One hundred parents of consecutively diagnosed children ...

journal_title：Pediatric blood & cancer

authors： McMurter B,Parker L,Fraser RB,Magee JF,Kozancyzn C,Fernandez CV

更新日期：2011-12-15 00:00:00

abstract：:Unstable hemoglobin variants represent a rare etiology of congenital hemolytic anemia. Without a high index of suspicion, plus proper laboratory testing and interpretation, the correct diagnosis can be elusive. We report on five children who were initially thought to have other congenital disorders such as hereditary ...

journal_title：Pediatric blood & cancer

authors： Yates AM,Mortier NA,Hyde KS,Hankins JS,Ware RE

更新日期：2010-12-15 00:00:00

abstract：BACKGROUND:Children with cancer may be at an increased risk of infection with hepatitis B virus (HBV) when levels of hepatitis B antibodies are reduced owing to chemotherapy-induced immunosuppression. This study evaluated the changes in HBV antibody status and HBV infections after chemotherapy in children with acute ly...

journal_title：Pediatric blood & cancer

authors： Choi YB,Lee NH,Yi ES,Kim YJ,Koo HH

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Cancer patients undergoing chemotherapy often develop anemia, which can increase the risk for transfusions and fatigue. The recombinant erythropoiesis-stimulating agent darbepoetin alfa can effectively treat chemotherapy-induced anemia (CIA) in adults, but limited data are available regarding its use in pedi...

journal_title：Pediatric blood & cancer

authors： Blumer J,Berg S,Adamson PC,Loew T,Rossi G,Hastings C

更新日期：2007-10-15 00:00:00

abstract：:Under and overweight, usually secondary to energy imbalance, are common complications of childhood chronic disease. A simple energy balance paradigm has been helpful in understanding the etiology of underweight and overweight in chronic disease, including malignant disease, particularly when measurements of total ener...

journal_title：Pediatric blood & cancer

authors： Reilly JJ

更新日期：2008-02-01 00:00:00

abstract：:Childhood obesity is a significant public health problem, affecting one in five children in the United States. At the crux of this issue is a dysregulation of energy intake and energy expenditure. This review will provide an overview on energy and nutrient balance. We discuss energy balance studies in children using i...

journal_title：Pediatric blood & cancer

authors： Tam CS,Ravussin E

更新日期：2012-01-01 00:00:00