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Single-cell analysis of lambda immunity regulation.

Abstract：

:We have examined expression of the lambdacI operon in single cells via a rex Colon, two colons gfp substitution. Although average fluorescence agreed with expectations for expression of lambda-repressor, fluorescence fluctuated greatly from cell-to-cell. Fluctuations in repressor concentration are not predicted by previous models and are tolerated in part by a regulatory response to DNA damage.

journal_name

J Mol Biol

journal_title

Journal of molecular biology

authors

Baek K,Svenningsen S,Eisen H,Sneppen K,Brown S

doi

10.1016/j.jmb.2003.09.037

keywords:

subject

Has Abstract

pub_date

2003-11-28 00:00:00

pages

363-72

issue

3

eissn

0022-2836

issn

1089-8638

pii

S0022283603011859

journal_volume

334

pub_type

杂志文章

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