当前位置： SCI文献检索 > BRAIN & DEVELOPMENT期刊下所有文献 > Vertebral artery insufficiency as a possible mechanism for sudden infant death--in vivo evidence does not support findings from postmortem studies.

Vertebral artery insufficiency as a possible mechanism for sudden infant death--in vivo evidence does not support findings from postmortem studies.

Abstract：

:Recent postmortem studies have suggested that sudden infant death syndrome (SIDS) might involve an underlying, gradual brain stem injury caused by repeated episodes of transiently compromised brain stem circulation. Autopsy studies have also reported that vertebral artery occlusion due to head rotations, such as occurs, e.g. during prone sleeping, would be a physiological phenomenon of infant atlantooccipital junction. The present study was undertaken to examine whether vertebral artery insufficiency does truly occur in live infants during such head rotations. We studied by transcranial doppler sonography the blood flow velocity of the basilar artery (BA) in 27 infants during head rotation from straight position to maximal rotation in three directions (left, right, dorsiflexion). No significant change in BA blood flow was seen between any head positions. Weight and gestational age, but not arterial pressure or hematocrit, of the infants were correlated with blood flow velocity. Our results suggest that brain stem circulation in live infants may not be compromised due to changing the head position, which is inconsistent with the postmortem findings showing insufficiency of brain stem circulation in both controls and those succumbed to SIDS. We hence propose that the brain stem pathology observed with SIDS is likely caused by other factors (e.g. systemic disturbance) rather than by mechanical obstruction of brain stem circulation.

journal_name

Brain Dev

journal_title

Brain & development

authors

Vanhatalo S,Nikolajev K,Kiekara O,Seuri R,Riikonen R

doi

10.1016/s0387-7604(03)00004-4

keywords:

subject

Has Abstract

pub_date

2003-08-01 00:00:00

pages

322-5

issue

5

eissn

0387-7604

issn

1872-7131

pii

S0387760403000044

journal_volume

25

pub_type

杂志文章

相关文献

BRAIN & DEVELOPMENT文献大全
  • Inappropriate intracranial hemodynamics in the natural course of MELAS.

    abstract：:The abnormalities of intracranial hemodynamics associated with strokelike episodes in MELAS are variable depend on the time phase from the onset of strokelike episodes and on the progression of the dementia state. To clarify the regional cerebral blood flows (rCBF) in the natural course of MELAS is very important to u...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2007.06.008

    authors： Nishioka J,Akita Y,Yatsuga S,Katayama K,Matsuishi T,Ishibashi M,Koga Y

    更新日期：2008-02-01 00:00:00

  • Hyperkinetic movement disorder in a child treated by globus pallidus stimulation.

    abstract：:We report herein the case of a 9-year-old girl with life-threatening hyperkinetic involuntary movement of unknown etiology. Medical treatment was ineffective for her stereotypy and choreoathetotic/ballistic movements, but bilateral stimulation of the globus pallidus immediately alleviated these symptoms. Pallidal deep...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2008.08.003

    authors： Sato K,Nakagawa E,Saito Y,Komaki H,Sakuma H,Sugai K,Sasaki M,Kaido T,Nakama H,Otsuki T

    更新日期：2009-06-01 00:00:00

  • Functional and morphometrical maturation of the brainstem auditory pathway.

    abstract：:The correlation between the functional and morphological maturation of the auditory pathway was studied in preterm and term infants, children and adults. As to the auditory brainstem response (ABR), peak latencies and I-V interpeak latencies (central transmission) gradually decreased during the third trimester and the...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(87)80092-x

    authors： Inagaki M,Tomita Y,Takashima S,Ohtani K,Andoh G,Takeshita K

    更新日期：1987-01-01 00:00:00

  • Surface electromyogram and muscle ultrasonography for detection of muscle fasciculations in pediatric peripheral neuropathy.

    abstract：:A 12-year-old girl presented with talipes equinus of both legs, attenuation of upper and lower limb tendon reflexes, thermal hyperalgesia, and reduction of vibratory sensation. On clinical examination, muscle twitches of fingers of both hands, as well as the abductor halluces and the dorsal interossei muscles of the r...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2017.02.006

    authors： Oguri M,Saito Y,Okazaki T,Matsumura W,Ohno K,Togawa M,Fukuda C,Saito Y,Nishino I,Maegaki Y

    更新日期：2017-08-01 00:00:00

  • Temporal trends in perinatal mortality and cerebral palsy: A regional population-based study in southern Japan.

    abstract：AIM:The prevalence of cerebral palsy (CP) has not decreased in developed countries over the past 30 years. We examined gestational age-specific trends in the prevalence of CP. METHODS:This unselected, population-based study was conducted in Miyazaki prefecture, Japan (10,000 deliveries annually), where 102,999 deliver...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2015.10.002

    authors： Kodama Y,Sameshima H,Ikenoue T

    更新日期：2016-04-01 00:00:00

  • Isolated Dandy-Walker malformation associated with brain stem dysgenesis in male sibs.

    abstract：:We describe two brothers with isolated Dandy-Walker malformation (DWM). Interestingly, brain stem dysgenesis and abnormal gyral pattern were also observed in the sibs. They presented with psychomotor retardation and macrocrania. Both suffered from hypotonia with brisk deep tendon reflexes and ataxic gait. They had bil...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2006.01.009

    authors： Abdel-Salam GM,Shehab M,Zaki MS

    更新日期：2006-09-01 00:00:00

  • HLA antigens, epilepsy and cytomegalovirus infection.

    abstract：:Thirty-one epileptic patients, selected from among 900 children with previous febrile convulsions and subsequent epilepsy, were typed for HLA antigens. In 16 of the 31 patients CMV was isolated from the urine shortly after the appearance of spontaneous fits; in the remaining 15 patients the virus was never detected. A...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(88)80008-1

    authors： Iannetti P,Morellini M,Raucci U,Cappellacci S

    更新日期：1988-01-01 00:00:00

  • Use of amplitude-integrated electroencephalography (aEEG) and near infrared spectroscopy findings in neonates with asphyxia during selective head cooling.

    abstract：BACKGROUND:Amplitude-integrated electroencephalogram (aEEG) at <6 h is the best single outcome predictor in term infants with perinatal asphyxia at normothermia. Hypothermia treatment has changed the cutoff values for outcome prediction by using time at onset of normal trace and SWC. Cerebral hemodynamics and oxygenati...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2011.06.005

    authors： Gucuyener K,Beken S,Ergenekon E,Soysal S,Hirfanoglu I,Turan O,Unal S,Altuntas N,Kazanci E,Kulali F,Koc E,Turkyilmaz C,Onal E,Atalay Y

    更新日期：2012-04-01 00:00:00

  • Prevalence of motor impairment in autism spectrum disorders.

    abstract：:Autism spectrum disorders (ASD) are manifest as impairments in social interaction, language and speech development, and the appearance of repetitive behaviors with restricted interests. Motor impairments in individuals with ASD have been categorized as "associated symptoms". The objective of this study was to describe...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2007.03.002

    authors： Ming X,Brimacombe M,Wagner GC

    更新日期：2007-10-01 00:00:00

  • Prognosis of infants with ankle clonus within the first year of life.

    abstract：:The present study was undertaken to clarify how we should assess the necessity of close follow-up in each case, when we first examine an infant with ankle clonus within the first year of life. The neurologic prognoses of 169 infants who had exhibited ankle clonus at least once during the first year of life were review...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(96)00069-1

    authors： Futagi Y,Otani K,Goto M

    更新日期：1997-01-01 00:00:00

  • Neurodevelopment evaluation in children with congenital hypothyroidism by Bayley-III.

    abstract：BACKGROUND:Congenital hypothyroidism is the most common reason of mental retardation, and normal neurological development can be provided by early and effective treatment. In this present study, it is aimed to compare neurological developments of patients in 6-42 months of age with congenital hypothyroidism and healthy...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2012.07.003

    authors： Komur M,Ozen S,Okuyaz C,Makharoblıdze K,Erdogan S

    更新日期：2013-05-01 00:00:00

  • Prenatal diagnosis of Menkes disease by genetic analysis and copper measurement.

    abstract：:Carrier detection for 12 women and prenatal diagnosis for six fetuses in Japanese families with a patient with Menkes disease (MNK) were performed by gene analysis and/or measurement of the copper concentration in cultured cells. Six out of eight mothers of MNK patients were carriers while two (25%) were not carriers....

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(02)00093-1

    authors： Gu YH,Kodama H,Sato E,Mochizuki D,Yanagawa Y,Takayanagi M,Sato K,Ogawa A,Ushijima H,Lee CC

    更新日期：2002-10-01 00:00:00

  • Congenital neurogenic muscular atrophy in megaconial myopathy due to a mutation in CHKB gene.

    abstract：:Choline kinase beta gene (CHKB) mutations have been identified in Megaconial Congenital Muscular Dystrophy (MDCMC) patients, a very rare inborn error of metabolism with 21 cases reported worldwide. We report the case of a Spanish boy of Caucasian origin who presented a generalized congenital muscular hypotonia, more i...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2015.05.008

    authors： Castro-Gago M,Dacruz-Alvarez D,Pintos-Martínez E,Beiras-Iglesias A,Arenas J,Martín MÁ,Martínez-Azorín F

    更新日期：2016-01-01 00:00:00

  • Childhood disintegrative disorder.

    abstract：:In 1908 a Viennese remedial educator Theodor Heller described six children under the name of dementia infantilis who had insidiously developed a severe mental regression between the 3rd and 4th years of life after normal mental development. Neuropathological and other medical conditions are sometimes associated with t...

    journal_title：Brain & development

    pub_type： 杂志文章,评审

    doi：10.1016/s0387-7604(02)00228-0

    authors： Mouridsen SE

    更新日期：2003-06-01 00:00:00

  • Comparison of the strengths and difficulties questionnaire (SDQ) scores between children with high-functioning autism spectrum disorder (HFASD) and attention-deficit/hyperactivity disorder (AD/HD).

    abstract：:The aim of this research was to compare the Strengths and Difficulties Questionnaire (SDQ) scores and subscale scores in children with high-functioning autism spectrum disorder (HFASD) and attention-deficit/hyperactivity disorder (AD/HD), and also to clarify the differences between parent- and teacher-assessed SDQ sco...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2009.09.009

    authors： Iizuka C,Yamashita Y,Nagamitsu S,Yamashita T,Araki Y,Ohya T,Hara M,Shibuya I,Kakuma T,Matsuishi T

    更新日期：2010-09-01 00:00:00

  • Antiepileptic effects of clobazam in children.

    abstract：:Many benzodiazepines used as anticonvulsants have nitrogen radicals in positions 1 and 4. Clobazam has nitrogen radicals in positions 1 and 5. We studied the antiepileptic effect of clobazam in 36 patients with intractable epilepsies in childhood. Their ages were 1 year 1 month to 16 years 5 months (mean 8 years). The...

    journal_title：Brain & development

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0387-7604(82)80102-2

    authors： Shimizu H,Abe J,Futagi Y,Onoe S,Tagawa T,Mimaki T,Yamatodani A,Kato M,Kamio M,Sumi K,Sugita T,Yabuuchi H

    更新日期：1982-01-01 00:00:00

  • Syndrome of septo-optic-pituitary dysplasia: the clinical spectrum.

    abstract：:Septo-optic-pituitary dysplasia is a syndrome characterized by abnormalities of midline brain structures, optic nerve hypoplasia, and congenital hypothalamic-pituitary insufficiency. Four infants, diagnosed as having clinical variations of this disorder, are described. The first had agenesis of the septum pellucidum a...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(86)80075-4

    authors： Morishima A,Aranoff GS

    更新日期：1986-01-01 00:00:00

  • MicroRNA-31 regulating apoptosis by mediating the phosphatidylinositol-3 kinase/protein kinase B signaling pathway in treatment of spinal cord injury.

    abstract：:Apoptosis is a highly conservative energy demand program for non-inflammatory cell death, which is extremely significant in normal physiology and disease. There are many techniques used for studying apoptosis. MicroRNA (miRNA) is closely related to cell apoptosis, and especially microRNA-31 (miR-31) is involved in apo...

    journal_title：Brain & development

    pub_type： 杂志文章,评审

    doi：10.1016/j.braindev.2019.04.010

    authors： Wang Y,Yuan Y,Gao Y,Li X,Tian F,Liu F,Du R,Li P,Wang F,Xu S,Wu X,Wang C

    更新日期：2019-09-01 00:00:00

  • Brain stem infarction in a 6-year-old boy with Down syndrome.

    abstract：:Infarct locations in children with arterial ischemic stroke have primarily been reported to be lobar or in the basal ganglia, and those in patients with Down syndrome (DS) and antiphospholipid syndrome (APS) are typically wide and multiple. No solitary brain stem infarctions have ever been reported in children with DS...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2019.02.013

    authors： Imagi T,Matsushita T,Matsushita M,Yae Y,Yokochi T,Kawano G,Akita Y,Ohbu K,Matsuishi T

    更新日期：2019-06-01 00:00:00

  • Predictive value of the early clinical signs in Rett disorder.

    abstract：:The British Isles Survey for Rett has registered 1,159 cases over up to 20 years. Indicators of health and severity, recorded at intervals throughout life, are drawn from clinical examinations, reports and postal questionnaires. This study aimed to establish the stability and predictive value of an early severity scor...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2004.10.007

    authors： Kerr AM,Prescott RJ

    更新日期：2005-11-01 00:00:00

  • Ictal EEG in patients with convulsions with mild gastroenteritis.

    abstract：:The aim of this study is to reveal detailed clinical manifestations and an evolution of ictal EEG discharges of convulsions with mild gastroenteritis (CwG). We recorded ictal EEGs of six patients with CwG. Clinical manifestations included loss of responsiveness, motion arrest, cyanosis, lateral eye deviation, and hemi...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2006.06.002

    authors： Maruyama K,Okumura A,Sofue A,Ishihara N,Watanabe K

    更新日期：2007-01-01 00:00:00

  • Developmental changes in brain activation and functional connectivity during response inhibition in the early childhood brain.

    abstract：:Response inhibition is an attention function which develops relatively early during childhood. Behavioral data suggest that by the age of 3, children master the basic task requirements for the assessment of response inhibition but performance improves substantially until the age of 7. The neuronal mechanisms underlyin...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2012.11.006

    authors： Mehnert J,Akhrif A,Telkemeyer S,Rossi S,Schmitz CH,Steinbrink J,Wartenburger I,Obrig H,Neufang S

    更新日期：2013-11-01 00:00:00

  • Ictal electroencephalographic findings of neonatal seizures in preterm infants.

    abstract：:The aim of this study is to clarify the characteristics of ictal EEG findings of neonatal seizures in preterm infants. Seizures associated with ictal EEG changes were recognized in nine infants with gestational age of less than 37 weeks. Propagation, migration, shifting, changes in morphology of ictal EEG discharges w...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2007.08.011

    authors： Okumura A,Hayakawa F,Kato T,Itomi K,Maruyama K,Kubota T,Suzuki M,Kidokoro H,Watanabe K

    更新日期：2008-04-01 00:00:00

  • Positron emission tomography with glucose hypermetabolism of a hypothalamic hamartoma in infantile spasms associated with Pallister-Hall syndrome.

    abstract：:Although hypothalamic hamartomas (HHs) have been shown to be intrinsically epileptogenic and to participate in the generation of gelastic seizures, no evidence has been reported regarding its contribution to the pathogenesis of infantile spasms. We describe a male infant with Pallister-Hall syndrome who had a large HH...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2009.09.003

    authors： Wakamoto H,Sumi A,Motoki T,Ohmori H

    更新日期：2010-09-01 00:00:00

  • A pilot study on the changes in immunity after ACTH therapy in patients with West syndrome.

    abstract：:Adrenocorticotropic hormone (ACTH) has been the first-line drug for the treatment of West syndrome, although the therapy has various adverse effects. ACTH depresses resistance to a variety of bacterial, viral, protozoal, and fungal agents. The timing of the various vaccinations is delayed after ACTH therapy in Japan, ...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2008.11.007

    authors： Ohya T,Nagai T,Araki Y,Yanagawa T,Tanabe T,Iyoda K,Kurihara M,Yamamoto K,Masunaga K,Iizuka C,Nagamitsu S,Yamashita Y,Awaya Y,Maekawa K,Matsuishi T,Research Group on Adverse Effects of Vaccination in Patients with Neurologic

    更新日期：2009-11-01 00:00:00

  • Lacosamide for children with paroxysmal kinesigenic dyskinesia.

    abstract：OBJECTIVES:This study was performed to evaluate the efficacy and tolerability of lacosamide (LCM) for paroxysmal kinesigenic dyskinesia (PKD) in children. METHODS:We retrospectively reviewed the medical charts of pediatric PKD patients (aged <16 years) treated with LCM. Data regarding demographic characteristics, prol...

    journal_title：Brain & development

    pub_type：

    doi：10.1016/j.braindev.2020.04.009

    authors： Furukawa G,Negishi Y,Takeuchi T,Ishihara N,Okumura A

    更新日期：2020-09-01 00:00:00

  • The treatment of acute polyradiculoneuritis with respiratory paralysis.

    abstract：:This paper reports 504 cases admitted with acute polyradiculoneuritis (AP) to Beijing Children's Hospital from 1975 through 1984. 343 of the 504 cases (68.1%) with AP had respiratory paralysis and in 198/504 (39.3%), tracheotomy was performed. In this study, none of the patients received steroids. We attempted to asse...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：

    authors： Wu HS,Yei QF,Liu TC,Zhang WC

    更新日期：1988-01-01 00:00:00

  • Long-term effectiveness of ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy.

    abstract：PURPOSE:We performed this study to evaluate the long-term efficacy and tolerability of ethosuximide (ESX), valproic acid (VPA), and lamotrigine (LTG) as initial monotherapies for patients with newly diagnosed childhood absence epilepsy. METHODS:We retrospectively reviewed the medical records of 128 patients (45 boys a...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2011.08.007

    authors： Hwang H,Kim H,Kim SH,Kim SH,Lim BC,Chae JH,Choi JE,Kim KJ,Hwang YS

    更新日期：2012-05-01 00:00:00

  • Modification of AMPA receptor properties following environmental enrichment.

    abstract：:Environmental enrichment results in many modifications in the brain such as structural, behavioural, and biochemical changes. alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type receptors for excitatory amino acid glutamate are recently found to be involved in neuronal plasticity. In this study, we ex...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2004.07.006

    authors： Naka F,Narita N,Okado N,Narita M

    更新日期：2005-06-01 00:00:00

  • Brain stem and spinal cord impairment in Rett syndrome: somatosensory and auditory evoked responses investigations.

    abstract：:Six females with Rett syndrome (RS)--all seriously motor disabled with clinical symptomatology indicating not only brain but also spinal cord impairment--were investigated using auditory and somatosensory evoked responses techniques. In all patients the responses representing the pathways through the upper spinal cord...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(87)80076-1

    authors： Badr GG,Witt-Engerström I,Hagberg B

    更新日期：1987-01-01 00:00:00