当前位置： SCI文献检索 > BRAIN & DEVELOPMENT期刊下所有文献 > Neurodevelopment evaluation in children with congenital hypothyroidism by Bayley-III.

Neurodevelopment evaluation in children with congenital hypothyroidism by Bayley-III.

Abstract：

BACKGROUND:Congenital hypothyroidism is the most common reason of mental retardation, and normal neurological development can be provided by early and effective treatment. In this present study, it is aimed to compare neurological developments of patients in 6-42 months of age with congenital hypothyroidism and healthy controls of the same age group prospectively by Bayley III test. METHODS:In this present study, neurological developments of 41 congenital hypothyroidism cases and 39 healthy controls, who applied to Pediatric Endocrinology Section of Mersin Children Hospital and Pediatric Neurology Outpatient Clinic of the Medical School at Mersin University between years 2009 and 2011, were evaluated by Bayley III test. RESULTS:Cognitive, language and global motor scores in addition to receptive communication, expressive communication, fine motor and gross motor subscores in children with congenital hypothyroidism were statistically significantly lower than those in the control group (p<0.05). It is detected that initiation dose and day of treatments, severity of hypothyroidism and time to normalization thyroid stimulating hormone had no statistically significant effects on neurological development of the study group (p>0.05). In both groups, as the education levels of mothers are increased, language development scores are also increased (p<0.05). Additionally, statistically significant increases in Bayley III scores except cognitive scores have been observed in both groups as the level of income is increased (p<0.05). CONCLUSIONS:Despite early and effective treatment in newborns with congenital hypothyroidism, retardation in neurological developmental has been detected. This situation can be related to influences on neurodevelopment in intrauterine period. According to our present knowledge, this study is the first case-control study in the literature that neurological developments of congenital hypothyroidism patients are evaluated with Bayley-III score.

journal_name

Brain Dev

journal_title

Brain & development

authors

Komur M,Ozen S,Okuyaz C,Makharoblıdze K,Erdogan S

doi

10.1016/j.braindev.2012.07.003

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

392-7

issue

5

eissn

0387-7604

issn

1872-7131

pii

S0387-7604(12)00166-0

journal_volume

35

pub_type

杂志文章

相关文献

BRAIN & DEVELOPMENT文献大全
  • Predictive value of the early clinical signs in Rett disorder.

    abstract：:The British Isles Survey for Rett has registered 1,159 cases over up to 20 years. Indicators of health and severity, recorded at intervals throughout life, are drawn from clinical examinations, reports and postal questionnaires. This study aimed to establish the stability and predictive value of an early severity scor...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2004.10.007

    authors： Kerr AM,Prescott RJ

    更新日期：2005-11-01 00:00:00

  • Breathing disorders in males with acquired encephalopathy.

    abstract：:Six boys affected by acquired encephalopathy with an abnormal breathing pattern in wakefulness were studied. Polygraphic recordings showed two different patterns in our population. In two brothers a periodic breathing pattern was recorded in the awake and sleep states. In the others, central apneas with or without tac...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(12)80180-x

    authors： Cirignotta F,Sforza E,Burroni M,Zappella M,Lugaresi E

    更新日期：1990-01-01 00:00:00

  • Dravet syndrome: early clinical manifestations and cognitive outcome in 37 Italian patients.

    abstract：:Aims of our study were to describe the early clinical features of Dravet syndrome (SMEI) and the neurological, cognitive and behavioral outcome. The clinical history of 37 patients with clinical diagnosis of SMEI, associated with a point mutation of SCN1A gene in 84% of cases, were reviewed with particular attention t...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2009.09.014

    authors： Ragona F,Brazzo D,De Giorgi I,Morbi M,Freri E,Teutonico F,Gennaro E,Zara F,Binelli S,Veggiotti P,Granata T

    更新日期：2010-01-01 00:00:00

  • Rett syndrome: report of eight cases.

    abstract：:The author reports eight cases of the Rett syndrome, or dementia-ataxia-autism, in girls. The cases satisfy the following criteria: Normal development in the first mos of life. Profound deterioration of the mental status over a period of several mos. Behavioral pseudoautistic abnormalities. Presence of neurological si...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(85)80030-9

    authors： Rolando S

    更新日期：1985-01-01 00:00:00

  • Towards early diagnosis and treatment to save children from catastrophic epilepsy -- focus on epilepsy surgery.

    abstract：OBJECTIVE:To analyze and to discuss whether by paying attention to the many recent advancements in the field of pediatric epilepsy surgery catastrophic childhood epilepsies caused by definitive or suspected structural lesions can be prevented more often these days in comparison to the past. METHODS:Based on data from ...

    journal_title：Brain & development

    pub_type： 杂志文章,评审

    doi：10.1016/j.braindev.2013.05.003

    authors： Holthausen H,Pieper T,Kudernatsch M

    更新日期：2013-09-01 00:00:00

  • Premonitory urges for tics in adult patients with Tourette syndrome.

    abstract：OBJECTIVE:Patients with Tourette syndrome (TS) often report characteristic sensory experiences, also called premonitory urges (PUs), which precede tic expression and have high diagnostic relevance. This study investigated the usefulness of a scale developed and validated in children and adolescents-the Premonitory Urge...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2012.12.010

    authors： Crossley E,Seri S,Stern JS,Robertson MM,Cavanna AE

    更新日期：2014-01-01 00:00:00

  • Cholinergic system disturbance in the West syndrome.

    abstract：:The effects of drug on the cholinergic system (atropine and physostigmine) were evaluated in acute tests in 12 infant patients with the West syndrome (WS) and in 12 older ones who had suffered from WS at typical ages, displaying various types of epileptic symptoms. In both groups paroxysmal EEG activity was inhibited ...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(12)80008-8

    authors： Rektor I,Svejdová M,Ménini C

    更新日期：1990-01-01 00:00:00

  • Cervical spinal cord compression in a child with cervicofacial actinomycosis.

    abstract：:Actinomycosis is a rare, chronic, suppurative, and slowly progressive granulomatous disease caused by a group of filamentous gram-positive anaerobic bacteria belonging to the normal flora of the oral cavity, gastrointestinal, and genitourinary tracts. It may involve several organs; however, spinal cord compression has...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2013.08.002

    authors： Hung PC,Wang HS,Chiu CH,Wong AM

    更新日期：2014-08-01 00:00:00

  • Is oxidative damage in operation in patients with hereditary spastic paraparesis?

    abstract：:Oxidative stress resulting from increased free radical production and/or defects in antioxidant defences may be the cause of various neurodegenerative disorders. In this study, the roles of oxygen free radicals, nitric oxide, superoxide dismutase, vitamin E and vitamin C were investigated in pure and complicated hered...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2008.12.014

    authors： Gücüyener K,Pinarli FG,Erbaş D,Hasanoğlu A,Serdaroğlu A,Topaloğlu H

    更新日期：2010-02-01 00:00:00

  • Two novel gap junction protein alpha 12 gene mutations in two Chinese patients with Pelizaeus-Merzbacher-like disease.

    abstract：:Pelizaeus-Merzbacher-like disease (PMLD) is a hypomyelinating disorder of the central nervous system caused by mutation in the gap junction protein alpha 12 (GJA12) gene. Uniparental disomy (UPD) is defined as the presence of a chromosome pair, in a diploid individual, that derives from only one parent. Here, we analy...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2009.03.013

    authors： Wang J,Wang H,Wang Y,Chen T,Wu X,Jiang Y

    更新日期：2010-03-01 00:00:00

  • Polygraphical study on age dependent epileptic encephalopathy--relationship between body movements during sleep and prognosis.

    abstract：:Body movements (BMs) during sleep in patients with age dependent epileptic encephalopathy (ADEE) were studied polysomnographically in order to clarify the underlying mechanism of intractability and the age dependent trend. Twenty patients were divided into two groups according to the prognosis of convulsions. In the g...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(86)80066-3

    authors： Iwakawa Y,Ogiso M,Suzuki H,Kawano Y,Koyama J,Shimohira M

    更新日期：1986-01-01 00:00:00

  • The natural history of somatic morbidity in disintegrative psychosis and infantile autism: a validation study.

    abstract：:In order to study the validity of disintegrative psychosis (DP) as defined in ICD-9, we compared the natural history of somatic morbidity of 13 patients given this diagnosis in childhood with a control group of 39 patients with infantile autism (IA) matched for gender, age, IQ and social class. Average follow-up time ...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(99)00045-5

    authors： Mouridsen SE,Rich B,Isager T

    更新日期：1999-10-01 00:00:00

  • Trinucleotide insertion in the SMN2 promoter may not be related to the clinical phenotype of SMA.

    abstract：BACKGROUND:More than 90% of spinal muscular atrophy (SMA) patients show homozygous deletion of SMN1 (survival motor neuron 1). They retain SMN2, a highly homologous gene to SMN1, which may partially compensate for deletion of SMN1. Although the promoter sequences of these two genes are almost identical, a GCC insertion...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2014.10.006

    authors： Harahap NI,Takeuchi A,Yusoff S,Tominaga K,Okinaga T,Kitai Y,Takarada T,Kubo Y,Saito K,Sa'adah N,Nurputra DK,Nishimura N,Saito T,Nishio H

    更新日期：2015-08-01 00:00:00

  • Serial MRI changes in a patient with infantile Alexander disease and prolonged survival.

    abstract：:Alexander disease is a major entity of leukodystrophy; magnetic resonance imaging (MRI) studies of the brain typically show extensive changes in the cerebral white matter with frontal predominance. Heterozygous missense mutations of GFAP are thought to be sufficient for the molecular diagnosis, which has widened the A...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2010.10.007

    authors： Shiihara T,Yoneda T,Mizuta I,Yoshida T,Nakagawa M,Shimizu N

    更新日期：2011-08-01 00:00:00

  • Childhood absence epilepsy: Elctroclinical features and diagnostic criteria.

    abstract：OBJECTIVE:To analyze the electroclinical features of children with childhood absence epilepsy (CAE) and discuss the diagnostic criteria for CAE. METHODS:The video-electroencephalogram (VEEG) database in our hospital was searched using "absence seizures" and "3-Hz generalized spike and waves (GSW)" as key-words. Other ...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2010.02.004

    authors： Ma X,Zhang Y,Yang Z,Liu X,Sun H,Qin J,Wu X,Liang J

    更新日期：2011-02-01 00:00:00

  • Clinical onset and prognosis of Asian children with organic acidemias, as detected by analysis of urinary organic acids using GC/MS, instead of mass screening.

    abstract：:Organic acidemias (OAs) have been detected worldwide in symptomatic patients using gas chromatography mass spectrometry. We diagnosed 188 Asian cases of OAs by analysis of urinary organic acids and investigated their clinical onset and outcome. Methylmalonic acidemia (MMA) was most common (74 cases), followed by propi...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2004.04.004

    authors： Hori D,Hasegawa Y,Kimura M,Yang Y,Verma IC,Yamaguchi S

    更新日期：2005-01-01 00:00:00

  • Increased fetal heart rate variability in periventricular leukomalacia.

    abstract：OBJECTIVE:This study used quantitative analysis to determine whether increased variability in fetal heart rate (FHR) is related to the risk of developing periventricular leukomalacia (PVL). METHODS:We analyzed 124 FHR traces of neonates delivered preterm at 27-33 weeks' gestation to 105 mothers. FHR traces 1-3h before...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2015.08.008

    authors： Kurahashi H,Okumura A,Kubota T,Kidokoro H,Maruyama K,Hayakawa M,Itakura A,Matsuzawa K,Yamamoto H,Kato T,Hayakawa F,Watanabe K

    更新日期：2016-02-01 00:00:00

  • Neuroprotective effect of human placental extract on hypoxic-ischemic brain injury in neonatal rats.

    abstract：:We investigated the neuroprotective effects of human placental extracts (HPE) and the effects of HPE on recovery of cognitive and behavioral function on hypoxic-ischemic brain injury in the newborn rat. The right common carotid arteries of 7-day-old rats were coagulated, and rats were then exposed to 8% oxygen. Immedi...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2012.01.009

    authors： Park JY,Byeon JH,Park SW,Eun SH,Chae KY,Eun BL

    更新日期：2013-01-01 00:00:00

  • MicroRNA-31 regulating apoptosis by mediating the phosphatidylinositol-3 kinase/protein kinase B signaling pathway in treatment of spinal cord injury.

    abstract：:Apoptosis is a highly conservative energy demand program for non-inflammatory cell death, which is extremely significant in normal physiology and disease. There are many techniques used for studying apoptosis. MicroRNA (miRNA) is closely related to cell apoptosis, and especially microRNA-31 (miR-31) is involved in apo...

    journal_title：Brain & development

    pub_type： 杂志文章,评审

    doi：10.1016/j.braindev.2019.04.010

    authors： Wang Y,Yuan Y,Gao Y,Li X,Tian F,Liu F,Du R,Li P,Wang F,Xu S,Wu X,Wang C

    更新日期：2019-09-01 00:00:00

  • Risk factors and outcomes of childhood ischemic stroke in Taiwan.

    abstract：:In this retrospective study, we reviewed the charts and collected clinical and radiographic data on children (age range, 1 month to 18 years) with symptoms and radiographic confirmation of ischemic stroke for the period of January 1996 to July 2006. Ninety-four children were enrolled. Eighty-eight had arterial ischemi...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2007.05.002

    authors： Lee YY,Lin KL,Wang HS,Chou ML,Hung PC,Hsieh MY,Lin JJ,Wong AM

    更新日期：2008-01-01 00:00:00

  • Vitamin B6 in acute encephalopathy with biphasic seizures and late reduced diffusion.

    abstract：BACKGROUND:The initial presentation of acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is indistinguishable from that of complex febrile seizures (FS), which poses a great diagnostic challenge for clinicians. Excitotoxicity is speculated to be the pathogenesis of AESD. Vitamin B6 (VB6) is ...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2020.02.002

    authors： Akiyama T,Toda S,Kimura N,Mogami Y,Hanaoka Y,Tokorodani C,Ito T,Miyahara H,Hyodo Y,Kobayashi K

    更新日期：2020-05-01 00:00:00

  • Hyperkinetic movement disorder in a child treated by globus pallidus stimulation.

    abstract：:We report herein the case of a 9-year-old girl with life-threatening hyperkinetic involuntary movement of unknown etiology. Medical treatment was ineffective for her stereotypy and choreoathetotic/ballistic movements, but bilateral stimulation of the globus pallidus immediately alleviated these symptoms. Pallidal deep...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2008.08.003

    authors： Sato K,Nakagawa E,Saito Y,Komaki H,Sakuma H,Sugai K,Sasaki M,Kaido T,Nakama H,Otsuki T

    更新日期：2009-06-01 00:00:00

  • Alterations of tetrahydrobiopterin biosynthesis and pteridine levels in mouse tissues during growth and aging.

    abstract：:In the present study, we investigated age-related changes in pteridine levels and enzymatic activity responsible for tetrahydrobiopterin biosynthesis in mouse tissues. Until about 15 weeks after the birth, the remarkable change of tetrahydrobiopterin (BH4) was observed in all tissues tested. Between 20 and 50 weeks af...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(00)00144-3

    authors： Yoshida YI,Eda S,Masada M

    更新日期：2000-09-01 00:00:00

  • Unilaterally and rapidly progressing white matter lesion and elevated cytokines in a patient with Tay-Sachs disease.

    abstract：:We report the case of a girl with Tay-Sachs disease who had convulsions and deteriorated rapidly after an upper respiratory infection at the age of 11 months. At the age of 16 months, her seizures became intractable and magnetic resonance imaging of the brain showed high signal intensity on T2-weighted images and mark...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2009.01.007

    authors： Hayase T,Shimizu J,Goto T,Nozaki Y,Mori M,Takahashi N,Namba E,Yamagata T,Momoi MY

    更新日期：2010-03-01 00:00:00

  • Eye contact and emotional face processing in 6-month-old infants: advanced statistical methods applied to event-related potentials.

    abstract：:Event-related potential (ERP) studies with infants are often limited by a small number of measurements. We introduce a weighted general linear mixed model analysis with a time-varying covariate, which allows for the efficient analysis of all available event-related potential data of infants. This method allows control...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2009.04.001

    authors： Stahl D,Parise E,Hoehl S,Striano T

    更新日期：2010-04-01 00:00:00

  • Peripheral nerve involvement in Werdnig-Hoffmann disease.

    abstract：:The number of large myelinated axons was markedly decreased in almost all the intramuscular nerve bundles included in 32 muscle biopsies from patients with Werdnig-Hoffmann disease compared to that in normals. The morphometric analysis of peripheral nerves in 5 epon-embedded sections also showed a selective loss of la...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(89)80040-3

    authors： Chien YY,Nonaka I

    更新日期：1989-01-01 00:00:00

  • Isolated Dandy-Walker malformation associated with brain stem dysgenesis in male sibs.

    abstract：:We describe two brothers with isolated Dandy-Walker malformation (DWM). Interestingly, brain stem dysgenesis and abnormal gyral pattern were also observed in the sibs. They presented with psychomotor retardation and macrocrania. Both suffered from hypotonia with brisk deep tendon reflexes and ataxic gait. They had bil...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2006.01.009

    authors： Abdel-Salam GM,Shehab M,Zaki MS

    更新日期：2006-09-01 00:00:00

  • Early-infantile epileptic encephalopathy with suppression-bursts, Ohtahara syndrome; its overview referring to our 16 cases.

    abstract：:Ohtahara syndrome (OS) is characterized by frequent tonic spasms, with or without clustering, of early onset within a few months of life, and a suppression-burst (S-B) pattern in electroencephalography (EEG). Tonic spasms occur in not only waking but also sleeping state in most cases. Partial seizures are observed in ...

    journal_title：Brain & development

    pub_type： 杂志文章,评审

    doi：10.1016/s0387-7604(01)00392-8

    authors： Yamatogi Y,Ohtahara S

    更新日期：2002-01-01 00:00:00

  • Progressive multifocal leukoencephalopathy in purine nucleoside phosphorylase deficiency.

    abstract：:Progressive multifocal leukoencephalopathy is a demyelinating disease caused by JC virus, an opportunistic infection of the central nervous system. Although the majority of cases are infected with the human immunodeficiency virus (HIV), other immunocompromised patients are also at risk. Purine nucleoside phosphorylase...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/j.braindev.2006.07.008

    authors： Parvaneh N,Ashrafi MR,Yeganeh M,Pouladi N,Sayarifar F,Parvaneh L

    更新日期：2007-03-01 00:00:00

  • Gammaglobulin therapy in a case of chronic relapsing dysimmune polyneuropathy.

    abstract：:A boy with chronic relapsing dysimmune polyneuropathy was treated with intravenous gammaglobulin injections for the fourth and fifth episodes, and showed rapid clinical improvement compared with in the three previous episodes, when he was treated by high dose steroid administration. ...

    journal_title：Brain & development

    pub_type： 杂志文章

    doi：10.1016/s0387-7604(12)80332-9

    authors： Taku K,Tamura T,Miike T

    更新日期：1990-01-01 00:00:00