Abstract:
:Prior to presentation, two physically fit adults, a 39-year-old male and 40-year-old female, began supplementation with an over-the-counter thyroid preparation marketed as a metabolic accelerator and fat loss aid, tiratricol. Both participants took the supplement for 5 weeks (3000-4000 mcg/d) and 3 weeks (6000 mcg/d), respectively. At presentation, both complained of lethargy, loss of appetite, and muscle weakness. Upon initial laboratory evaluation, results revealed low thyroid stimulating hormone with profoundly elevated T3 values in both patients. After an extensive review of the literature, the cause of the problem was found to be the nutritional supplement they consumed contained tiratricol. After discontinuation of the supplement, thyroid levels slowly returned to baseline 40 days and 5 months later, respectively.
journal_name
Int J Sport Nutr Exerc Metabauthors
Scally MC,Hodge Adoi
10.1123/ijsnem.13.1.112keywords:
subject
Has Abstractpub_date
2003-03-01 00:00:00pages
112-6issue
1eissn
1526-484Xissn
1543-2742journal_volume
13pub_type
杂志文章abstract::Dietary supplementation (SUP) has become a significant part of athletic training. Studies indicate that creatine (Cr) can enhance short-duration, high-intensity activities. This study examined the effect of 21 days of low dose Cr SUP ( approximately 7.7 g/day) and resistance training on force output, power output, dur...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1123/ijsnem.10.3.235
更新日期:2000-09-01 00:00:00
abstract:PURPOSE:To investigate the effects of polysaccharide from Gynostemma pentaphyllum on antioxidant activity in skeletal muscle of mice exercised to exhaustion. METHODS:Three polysaccharide fractions were obtained from G. pentaphyllum polysaccharide (GPP) and termed GPP1-a, GPP2-b, and GPP3-a. Gas chromatography (GC) and...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.22.6.479
更新日期:2012-12-01 00:00:00
abstract::The effects of adaptation to a high-fat diet on endurance performance are equivocal, and there is little data regarding the effects on high-intensity exercise performance. This study examined the effects of a high-fat/moderate protein diet on submaximal, maximal, and supramaximal performance. Twenty non-highly trained...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1123/ijsnem.13.4.466
更新日期:2003-12-01 00:00:00
abstract::The purpose of this study was to determine the effect of pre-exercise high carbohydrate meals with high glycemic index (HGI) or low glycemic index (LGI) on blood leukocyte redistribution during subsequent endurance exercise. Eight male subjects performed a 90-min run on a treadmill at 70 % VO2max 3 h after ingesting a...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Functional hypothalamic amenorrhea is common among female athletes and may be difficult to treat. Restoration of menses (ROM) is crucial to prevent deleterious effects to skeletal and reproductive health. OBJECTIVES:To determine the natural history of menstrual disturbances in female college athletes manage...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.22.2.98
更新日期:2012-04-01 00:00:00
abstract::The impact of altered blood glucose concentrations on exercise metabolism and performance after a low carbohydrate (CHO) diet was investigated. In random order, 1 wk apart, 9 trained men underwent euglycemic (CI) or placebo (PI) clamps, while performing up to 150 min of cycling at 70% VO2(max), after 48 h on a low CHO...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2005-04-01 00:00:00
abstract::Delayed onset muscle soreness (DOMS) following eccentric exercise is associated with increased inflammation which can be debilitating. Incorporation of long-chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA), eicosapentaenoic acid, and docosahexaenoic acid into membrane phospholipids provides anti-inflammatory, p...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2020-0238
更新日期:2021-01-20 00:00:00
abstract::Twelve healthy active subjects (6 male, 6 female) performed 60 min of exercise (60% VO(2max)) on 3 occasions after supplementing with L-Carnitine L-tartrate (LCLT) or placebo. Each subject received a chronic dose, an acute dose, and placebo in a randomized, double-blind crossover design. Dietary intake and exercise we...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.15.4.386
更新日期:2005-08-01 00:00:00
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journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.23.1.31
更新日期:2013-02-01 00:00:00
abstract::The purpose of the current study was to evaluate changes in body composition, metabolic rate, and hormones during postcompetition recovery. Data were collected from natural physique athletes (7 male/8 female) within one week before (T1) competition, within one week after (T2), and 4-6 weeks after (T3) competition. Mea...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2017-0038
更新日期:2017-10-01 00:00:00
abstract::Six weeks (3 times/wk) of sprint-interval training (SIT) or continuous endurance training (CET) promote body-fat losses despite a substantially lower training volume with SIT. In an attempt to explain these findings, the authors quantified VO₂ during and after (24 h) sprint-interval exercise (SIE; 2 min exercise) vs. ...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.22.4.276
更新日期:2012-08-01 00:00:00
abstract::It is the position of Sports Dietitians Australia (SDA) that adolescent athletes have unique nutritional requirements as a consequence of undertaking daily training and competition in addition to the demands of growth and development. As such, SDA established an expert multidisciplinary panel to undertake an independe...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2014-0031
更新日期:2014-10-01 00:00:00
abstract::This study compared type of habitual exercise and meal form on diet-induced thermogenesis (DIT) in 29 men age 19-28 yr. Resting metabolic rate (RMR) and DIT response to solid-meal (bar) vs. liquid-meal (shake) ingestion were measured via indirect calorimetry; classifications were sedentary (n = 9), endurance trained (...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.21.1.11
更新日期:2011-02-01 00:00:00
abstract::The aim of this investigation was to determine the efficacy of a caffeine-containing energy drink to improve physical performance of elite field hockey players during a game. On 2 days separated by a week, 13 elite field hockey players (age and body mass = 23.2 ± 3.9 years and 76.1 ± 6.1 kg) ingested 3 mg of caffeine ...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.2015-0128
更新日期:2016-02-01 00:00:00
abstract::This study characterized body composition profiles of elite American heptathletes and cross-validated skinfold (SKF) and bioelectrical impedance analysis (BIA) field method equations for estimation of percent body fat (%Fat) using dual energy x-ray absorptiometry (DXA) as the criterion. Weight, height, fat mass (FM), ...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.11.2.162
更新日期:2001-06-01 00:00:00
abstract::This study determined normative data for sweat rate (SR) and whole-body (WB) sweat sodium concentration [Na+] in athletes indigenous to a tropical climate, categorized by age, gender, and sport classification. We analyzed data from 556 athletes (386 adult and 170 young) in endurance (END), team/ball (TBA), and combat ...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2019-0299
更新日期:2020-05-25 00:00:00
abstract::We sought to assess the accuracy of current or developing new prediction equations for resting metabolic rate (RMR) in adolescent athletes. RMR was assessed via indirect calorimetry, alongside known predictors (body composition via dual-energy X-ray absorptiometry, height, age, and sex) and hypothesized predictors (ra...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2019-0323
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abstract::Opuntia ficus indica (OFI) has many physiological effects, but a relationship between OFI and heart-rate variability (HRV) has never been established. The aim of this study was to describe the effects of a diet supplement of OFI on HRV in athletes. The first day, heart rate (HR) was measured at rest in supine (SU) and...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.18.2.169
更新日期:2008-04-01 00:00:00
abstract::To examine the effects of a 3-day high carbohydrate (H-CHO) and low carbohydrate (L-CHO) diet on 45 min of cycling exercise, 12 endurance-trained cyclists performed a 45-min cycling exercise at 82 +/- 2% VO2peak following an overnight fast, after a 6-day diet and exercise control. The 7-day protocol was repeated under...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2004-02-01 00:00:00
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journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.18.1.1
更新日期:2008-02-01 00:00:00
abstract::To defend against hydrogen cation accumulation and muscle fatigue during exercise, sodium bicarbonate (NaHCO3) ingestion is commonplace. The individualized dose-response relationship between NaHCO3 ingestion and blood biochemistry is unclear. The present study investigated the bicarbonate, pH, base excess and sodium r...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章,随机对照试验
doi:10.1123/ijsnem.2015-0286
更新日期:2016-10-01 00:00:00
abstract::The aim of this study was to conduct a systematic review of the effects of probiotic supplementation on physically active individuals. The participants, interventions, comparisons, outcome and study design inclusion criteria were (a) studies involving healthy adults or older subjects of both sexes who did physical exe...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2018-0227
更新日期:2019-09-01 00:00:00
abstract::The current study examined the effect of sprint interval exercise on postexercise oxygen consumption, respiratory-exchange ratio (RER), substrate oxidation, and blood pressure in adolescents. Participants were 10 normal-weight healthy youth (7 female), age 15-18 years. After overnight fasts, each participant undertook...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1123/ijsnem.22.1.47
更新日期:2012-02-01 00:00:00
abstract::Caffeine and creatine are ingredients in the most popular dietary supplements consumed by soccer players. However, some products may not contain the disclosed amounts of the ingredients listed on the label, compromising the safe usage and the effectiveness of these supplements. Therefore, the aim of this study was to ...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2015-0134
更新日期:2016-08-01 00:00:00
abstract::The authors compared the effectiveness of daily (DAY) versus alternate day (ALT) oral iron supplementation in athletes with suboptimal iron. Endurance-trained runners (nine males and 22 females), with serum ferritin (sFer) concentrations <50 μg/L, supplemented with oral iron either DAY or ALT for 8 weeks. Serum ferrit...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2019-0310
更新日期:2020-03-27 00:00:00
abstract::Low bone-mineral density (BMD) is associated with menstrual dysfunction and negative energy balance in the female athlete triad. This study determines BMD in elite female endurance runners and the associations between BMD, menstrual status, disordered eating, and training volume. Forty-four elite endurance runners par...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.20.5.418
更新日期:2010-10-01 00:00:00
abstract::The aim of this study was to evaluate the frequency of dietary supplement (DS) use among elite Finnish athletes in 2002 and 2009. In 2009, the authors also wanted to examine the reasons for athletes' DS use, whether athletes feel they have experienced benefits from their supplement use, and whether athletes had had an...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.21.4.271
更新日期:2011-08-01 00:00:00
abstract::The effects of a commercial sports drink on performance in high-intensity cycling was investigated. Nine well-trained subjects were asked to complete a set amount of work as fast as possible (time trial) following 24 h of dietary (subjects were provided with food, energy 57.4+/-2.4 kcal/kg and carbohydrate 9.1+/-0.4 g...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1123/ijsnem.14.5.541
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:Time spent in sedentary activities (such as watching television) has previously been associated with several risk factors for cardiovascular disease (CVD) such as increased low-density lipoprotein cholesterol (LDL-C). Little is known about associations with lipoprotein subfractions. Using television and comp...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.2013-0117
更新日期:2014-02-01 00:00:00
abstract::The angiotensin-I-converting enzyme (ACE) I/D gene polymorphism has been studied for its role in determining habitual physical activity level, but there is no information from Asian populations. The objective of this study was to determine whether this ACE gene polymorphism was associated with physical activity level ...
journal_title:International journal of sport nutrition and exercise metabolism
pub_type: 杂志文章
doi:10.1123/ijsnem.22.3.192
更新日期:2012-06-01 00:00:00