Preterm premature rupture of the membranes and antioxidants: the free radical connection.

Abstract:

AIM:To discuss the role of oxidant stress in preterm, premature rupture of the membranes (PPROM). RESULTS:There is evidence to suggest that preterm, premature rupture of the membranes occurs secondary to focal collagen damage in the fetal membranes. CONCLUSION:Oxidant stress caused by increased ROS formation and/or antioxidant depletion may disrupt collagen and cause premature membrane rupture. We propose that supplementation with vitamins C and E may synergistically protect the fetal membranes, and decrease the risks of PPROM.

journal_name

J Perinat Med

authors

Wall PD,Pressman EK,Woods JR Jr

doi

10.1515/JPM.2002.071

keywords:

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

447-57

issue

6

eissn

0300-5577

issn

1619-3997

journal_volume

30

pub_type

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