Abstract:
:The evidences that p16 and cyclin D alterations occur in the earlier stages of many human cancers and that its immunolocalization can be used to study the cell cycle regulation, coupled with the possibility that chronic use of carbamide peroxide would induce DNA damage and cell cycle alteration, prompted us to analyse the effect of carbamide peroxide on the immunolocalization of these proteins in rat oral mucosa. Ten male Wistar rats were selected and submitted to topical application of 35% carbamide peroxide over buccal mucosa. The procedures were carried out twice a week for 3 months consecutively. The animals were killed after the last treatment and the buccal mucosa was removed and stored at -70 degrees C. Only distilled water was applied over the buccal mucosa of the control animals. The biotin-streptavidin amplified system was used for identification of cyclin D and p16 antigens and the percentage of basal and suprabasal cells positive for each one were obtained. The results did not show any difference between the experimental and control groups regarding the immunolocalization of cyclin D and p16. In conclusion, the present study showed that chronic use of carbamide peroxide does not induce cell cycle alteration in the oral mucosa of rats.
journal_name
J Oral Rehabiljournal_title
Journal of oral rehabilitationauthors
Gomez RS,de Castro Albuquerque R,Dutra RA,Vasconcellos WA,Reis DA,Gomez RS,Gomez MVdoi
10.1046/j.1365-2842.2002.00944.xkeywords:
subject
Has Abstractpub_date
2002-09-01 00:00:00pages
906-9issue
9eissn
0305-182Xissn
1365-2842pii
944journal_volume
29pub_type
杂志文章abstract::The aim of this study was to measure the colour stability and viscoelastic properties of three commercially available soft lining materials in vitro, by exposing them to 3% erythrosine, tartrazine and sunset yellow solutions. The colour changes were determined using a computer controlled spectrophotometer. The colour ...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1046/j.1365-2842.1999.00477.x
更新日期:1999-10-01 00:00:00
abstract::This study reports a prospective clinical trial comparing a carbon fibre reinforced carbon (CFRC) endodontic post with a conventional prefabricated post. Twenty-seven single rooted maxillary anterior teeth in 18 patients (nine males and nine females; age range 18-60 years) were restored either with a CFRC post or a wr...
journal_title:Journal of oral rehabilitation
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2842.2003.01178.x
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:A network meta-analysis (NMA) of randomised clinical trials (RCTs) was performed aiming to compare the treatment outcome of dry needling, acupuncture or wet needling using different substances in managing myofascial pain of the masticatory muscles (TMD-M). METHOD:An electronic search was undertaken to identi...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章,meta分析,评审
doi:10.1111/joor.12960
更新日期:2020-07-01 00:00:00
abstract::Twenty-one methylmethacrylate screw implants were inserted in the jaws of three Labrador dogs. Clinical, radiographic, microscopic and fluorescence microscopic examinations were performed. Direct bone-implant contact was found in all firm implants, and the density of the alveolar bone increased towards the screw surfa...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/j.1365-2842.1975.tb00916.x
更新日期:1975-07-01 00:00:00
abstract::The strength of a modern, low metal:glass ratio, metal-reinforced glass-ionomer cement was measured evaluating a number of protective barriers: one light-cured resin, two solvent-based dental varnishes and petroleum jelly. The cement was exposed to water at 10 and 60 min from start of mix. The results obtained with th...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1046/j.1365-2842.1998.00282.x
更新日期:1998-07-01 00:00:00
abstract::The purpose of this study was to develop standardized reproducible testing methods for evaluating physical properties of periodontal dressing materials. Three commercial compositions (Coe-Pak, Coe-Pak Hard & Fast Set and WondrPak) were studied. Working and setting times were determined by observing the continuous chan...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/j.1365-2842.1986.tb00681.x
更新日期:1986-11-01 00:00:00
abstract::Alterations of body sway caused by isometric contractions of the jaw muscles have been reported previously. The objective of this study was to test if motor tasks of the masticatory system with different control demands affect body posture differently during quiet stance. Position and sway displacements of the center ...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/j.1365-2842.2011.02211.x
更新日期:2011-10-01 00:00:00
abstract::A study was conducted to evaluate the accuracy of casts made from stock tray and custom tray impressions using polysiloxane impression material. The results indicate that all casts distort but that impressions made from custom trays were more accurate and consistent in reproduction than were stock tray impressions. ...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1046/j.1365-2842.1998.00306.x
更新日期:1998-08-01 00:00:00
abstract::The viscoelastic properties of denture base polymers, such as poly(methylmethacrylate) (PMMA), polycarbonate (PC), polysulfone (PSF) and polyethersulfone (PES) which have been used in current clinical dentistry were investigated. In addition, water absorption, diffusion coefficient of water into material, cubical expa...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1046/j.1365-2842.2000.00545.x
更新日期:2000-06-01 00:00:00
abstract::The effects of mechanical stimulation of denture-bearing mucosa on the perception of mandibular position was tested in five patients wearing dentures. In order to produce mucosal stimulation of different intensities, five types of a punctate stimulus plate each having a different number of raised points was used. A hy...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/j.1365-2842.1992.tb01494.x
更新日期:1992-11-01 00:00:00
abstract::Thermal diffusivity values for glass ionomer and polycarboxylate cements have been determined for varying proportions of cement powder and liquid. Diffusivity is observed to be an increasing function of powder/liquid ratio. This is discussed in relation to the application of these cements as cavity bases. ...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/j.1365-2842.1984.tb00578.x
更新日期:1984-05-01 00:00:00
abstract::This article provides a review of somatosensory and motor pathways and processes involved in oral sensorimotor function and dysfunction. It reviews somatosensory processes in peripheral tissues, brainstem and higher brain centres such as thalamus and cerebral cortex, with a particular emphasis on nociceptive mechanism...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2842.2006.01623.x
更新日期:2006-04-01 00:00:00
abstract:UNLABELLED:The electromyographic (EMG) activity of the masseter and the anterior temporalis muscles were compared between 60 healthy controls and 61 myogenous craniomandibular disorder (CMD) patients. Subjects were asked to clench at 10% and at 50% of their maximum voluntary clenching level. The effects of CMD, age and...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/j.1365-2842.1994.tb01125.x
更新日期:1994-01-01 00:00:00
abstract::Fracture of porcelain fused to metal veneering may cause premature failure of fixed partial prosthodontics. Through the use of intra-oral composite bonded porcelain repair systems, the replacement of the prosthetic reconstruction can be avoided. The aim of this study was to evaluate the shear bond strength of porcelai...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1046/j.1365-2842.1999.00346.x
更新日期:1999-02-01 00:00:00
abstract::We report here on a patient with bilateral cleft lip and palate (BCLP) and a missing premaxilla, who underwent dentoalveolar reconstruction of the cleft and premaxillary alveolus using endosteal implants after bone grafting. The patient, whose maxillary incisors and premaxilla were missing, had corticocancellous bone ...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1046/j.1365-2842.2003.00999.x
更新日期:2003-01-01 00:00:00
abstract::Some alginate impression materials produce rough, chalky, soft surfaces on gypsum casts. This is recognized by various standards, which include tests for an alginate's compatibility with gypsum, and its capacity to record details and impart these to a gypsum cast. These qualities were looked at in this study. The meth...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/j.1365-2842.1986.tb01559.x
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:There is little evidence regarding the reliability of CPT and PT measurements to gauge mandibular perception. Thus, this study aimed to evaluate the test-retest reliability of CPT and PT values obtained from the mandibular oral mucosa and to test the bilateral differences in CPT and PT values obtained from t...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/joor.12777
更新日期:2019-06-01 00:00:00
abstract::A marginal gap exists between the amalgam restoration and the cavity walls. At this interface, there is a constant percolation of fluid containing ions, molecules and bacteria. With time, corrosion products of the amalgam components seal the gap at the amalgam/tooth interface. The corrosion processes for conventional ...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2842.1995.tb00242.x
更新日期:1995-02-01 00:00:00
abstract::There is an increase in elderly dentate adults who will retain more of their natural teeth, and thus the demand for restorative dental services among them will be high. In Finland, systematic dental care for old people has not been organized. Health centres have mainly targeted the development of dental care for child...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1046/j.1365-2842.2002.00903.x
更新日期:2002-05-01 00:00:00
abstract::This review evaluates the evidence for the diagnostic efficacy of cone beam computed tomography (CBCT) for impacted teeth and associated features. PubMed, Embase and the Cochrane Library were searched using specific indexing terms and reference lists were hand searched. Two reviewers selected relevant publications on ...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2842.2010.02141.x
更新日期:2011-03-01 00:00:00
abstract::Thirty-seven white Caucasian subjects with unsatisfactory dentures were tested for interocclusal thickness discrimination threshold. New dentures were prepared and the test was repeated on days 1, 4 and 90 (from delivery). Eight patients whose situation was still unsatisfactory were given osseointegrated implant ancho...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/j.1365-2842.1994.tb01137.x
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND:Tenofovir disoproxil fumarate (TDF), a primary antiretroviral agent used to treat AIDS, triggers systematic bone loss. However, the effect of TDF on osteopenia or osteoporosis in the jaw remains unclear. TDF-induced bone loss in the jaw, if any, likely involves mandible-derived mesenchymal stem cells (MMSCs)...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/joor.12840
更新日期:2020-11-01 00:00:00
abstract::The aim of this study was to examine whether sectioning of the lateral branches of the hypoglossal nerves (l-XII) in young male rats affects regulation of body weight, food intake and water intake in their period of growth by using a linear fixed effects model or not. Three groups of the rats were prepared according t...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/j.1365-2842.2009.01986.x
更新日期:2009-09-01 00:00:00
abstract::Quality control is very important in relation to invasive and lengthy treatments, such as integrated orthodontic and surgical correction of dentofacial deformities. The aim of this cross-sectional study was to compare self-reported somatosensory disturbances and quantitative sensory testing (QST) findings between two ...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/j.1365-2842.2010.02059.x
更新日期:2010-05-01 00:00:00
abstract::The aim of this study was to evaluate the effect of oscillating forces upon the flow of five dental cements. A laboratory investigation was carried out using a crown and die. It showed that the application of oscillating forces improved the flow of the tested dental cements when combined with low static loads and wide...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1046/j.1365-2842.1999.00459.x
更新日期:1999-11-01 00:00:00
abstract::Frontal chewing patterns have been classified in a manual and visual way on recorded movement tracks. The main aim of this study was to use a chain code method to extract the direction and curvature features of the tracks in the frontal plane. The test results indicate that the chain code can stand for the direction a...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/j.1365-2842.1995.tb01570.x
更新日期:1995-03-01 00:00:00
abstract::The preservation and restoration of severely weakened pulpless teeth is a difficult and relatively unpredictable procedure. This study evaluated the resistance to fracture of experimentally weakened bovine roots internally reconstructed with different filling materials in combination with prefabricated post compared w...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1046/j.1365-2842.2003.00990.x
更新日期:2003-06-01 00:00:00
abstract::This study examined the stress reducing capacity of varying thicknesses of unfilled resin in a Class V cavity. A two dimensional plane strain mesh of a Class V cavity, 3 mm in diameter and 2 mm deep, was produced and the thickness of the unfilled resin layer was varied from 0 to 80 microm. A polymerization shrinkage o...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1046/j.1365-2842.1999.00393.x
更新日期:1999-05-01 00:00:00
abstract::In a previous study it was found that the distance between the borders of the comfortable zone was considerably wider when the zone was recorded statically rather than dynamically. However, it was not reported how condylar displacements may be related to the zonal borders. Therefore, an attempt is made in the present ...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章
doi:10.1111/j.1365-2842.1979.tb00398.x
更新日期:1979-01-01 00:00:00
abstract::There is a consensus on treatment strategies for temporomandibular disorders (TMDs) being reversible. Among reversible therapies, physiotherapy is often chosen for the treatment of TMD pain and dysfunction because it is simple and non-invasive, it has a low cost as compared with other treatments, it allows an easy sel...
journal_title:Journal of oral rehabilitation
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2842.2005.01513.x
更新日期:2005-11-01 00:00:00