GPR99, a new G protein-coupled receptor with homology to a new subgroup of nucleotide receptors.

abstract：BACKGROUND:The MYB gene family comprises one of the richest groups of transcription factors in plants. Plant MYB proteins are characterized by a highly conserved MYB DNA-binding domain. MYB proteins are classified into four major groups namely, 1R-MYB, 2R-MYB, 3R-MYB and 4R-MYB based on the number and position of MYB r...

journal_title：BMC genomics

authors： Katiyar A,Smita S,Lenka SK,Rajwanshi R,Chinnusamy V,Bansal KC

更新日期：2012-10-10 00:00:00

abstract：BACKGROUND:Mango fruits contain a broad spectrum of phenolic compounds which impart potential health benefits; their biosynthesis is catalysed by enzymes in the phenylpropanoid-flavonoid (PF) pathway. The aim of this study was to reveal the variability in genes involved in the PF pathway in three different mango variet...

journal_title：BMC genomics

authors： Hoang VL,Innes DJ,Shaw PN,Monteith GR,Gidley MJ,Dietzgen RG

更新日期：2015-07-30 00:00:00

abstract：BACKGROUND:Decapods are an order of crustaceans which includes shrimps, crabs, lobsters and crayfish. They occur worldwide and are of great scientific interest as well as being of ecological and economic importance in fisheries and aquaculture. However, our knowledge of their biology mainly comes from the group which i...

journal_title：BMC genomics

authors： Nong W,Chai ZYH,Jiang X,Qin J,Ma KY,Chan KM,Chan TF,Chow BKC,Kwan HS,Wong CKC,Qiu JW,Hui JHL,Chu KH

更新日期：2020-01-09 00:00:00

abstract：BACKGROUND:The t(12;21)(p13;q22) translocation is found in 20 to 25% of cases of childhood B-lineage acute lymphoblastic leukemia (B-ALL). This rearrangement results in the fusion of ETV6 (TEL) and RUNX1 (AML1) genes and defines a relatively uniform category, although only some patients suffer very late relapse. TEL/AM...

journal_title：BMC genomics

authors： Gandemer V,Rio AG,de Tayrac M,Sibut V,Mottier S,Ly Sunnaram B,Henry C,Monnier A,Berthou C,Le Gall E,Le Treut A,Schmitt C,Le Gall JY,Mosser J,Galibert MD

更新日期：2007-10-23 00:00:00

abstract：BACKGROUND:Alcohol dehydrogenases (ADHs) in plants are encoded by a multigene family. ADHs participate in growth, development, and adaptation in many plant species, but the evolution and function of the ADH gene family in sugarcane is still unclear. RESULTS:In the present study, 151 ADH genes from 17 species including...

journal_title：BMC genomics

authors： Su W,Ren Y,Wang D,Su Y,Feng J,Zhang C,Tang H,Xu L,Muhammad K,Que Y

更新日期：2020-07-29 00:00:00

abstract：BACKGROUND:Sugarcane (Saccharum spp.) is predominantly an autopolyploid plant with a variable ploidy level, frequent aneuploidy and a large genome that hampers investigation of its organization. Genetic architecture studies are important for identifying genomic regions associated with traits of interest. However, due t...

journal_title：BMC genomics

authors： Balsalobre TW,da Silva Pereira G,Margarido GR,Gazaffi R,Barreto FZ,Anoni CO,Cardoso-Silva CB,Costa EA,Mancini MC,Hoffmann HP,de Souza AP,Garcia AA,Carneiro MS

更新日期：2017-01-11 00:00:00

abstract：BACKGROUND:Human genetic variation produces the wide range of phenotypic differences that make us individual. However, little is known about the distribution of variation in the most conserved functional regions of the human genome. We examined whether different subsets of the conserved human genome have been subjected...

journal_title：BMC genomics

authors： Davidson S,Starkey A,MacKenzie A

更新日期：2009-12-16 00:00:00

abstract：BACKGROUND:Flammulina filiformis (previously known as Asian F. velutipes) is a popular commercial edible mushroom. Many bioactive compounds with medicinal effects, such as polysaccharides and sesquiterpenoids, have been isolated and identified from F. filiformis, but their biosynthesis and regulation at the molecular l...

journal_title：BMC genomics

authors： Chen J,Li JM,Tang YJ,Ma K,Li B,Zeng X,Liu XB,Li Y,Yang ZL,Xu WN,Xie BG,Liu HW,Guo SX

更新日期：2020-10-17 00:00:00

abstract：BACKGROUND:Fusarium head blight (FHB), caused mainly by Fusarium graminearum (Fg) Schwabe (teleomorph: Gibberellazeae Schwble), brings serious damage to wheat production. Chinese wheat landrace Wangshuibai is one of the most important resistance sources in the world. The knowledge of mechanism underlying its resistance...

journal_title：BMC genomics

authors： Xiao J,Jin X,Jia X,Wang H,Cao A,Zhao W,Pei H,Xue Z,He L,Chen Q,Wang X

更新日期：2013-03-21 00:00:00

abstract：BACKGROUND:Sacha Inchi (Plukenetia volubilis L., Euphorbiaceae) is a potential oilseed crop because the seeds of this plant are rich in unsaturated fatty acids (FAs). In particular, the fatty acid composition of its seed oil differs markedly in containing large quantities of α-linolenic acid (18C:3, a kind of ω-3 FAs)....

journal_title：BMC genomics

authors： Wang X,Xu R,Wang R,Liu A

更新日期：2012-12-20 00:00:00

abstract：BACKGROUND:Identification of genes with ascending or descending monotonic expression patterns over time or stages of stem cells is an important issue in time-series microarray data analysis. We propose a method named Monotonic Feature Selector (MFSelector) based on a concept of total discriminating error (DEtotal) to i...

journal_title：BMC genomics

authors： Wang HW,Sun HJ,Chang TY,Lo HH,Cheng WC,Tseng GC,Lin CT,Chang SJ,Pal N,Chung IF

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:In mammals, CEACAM1 and closely related members represent paired receptors with similar extracellular ligand-binding regions and cytoplasmic domains with opposing functions. Human CEACAM1 and CEACAM3 which have inhibitory ITIM/ITSM and activating ITAM-like motifs, respectively, in their cytoplasmic regions a...

journal_title：BMC genomics

authors： Zimmermann W,Kammerer R

更新日期：2016-11-16 00:00:00

abstract：BACKGROUND:The desiccation-tolerant moss Bryum argenteum is an important component of the Biological Soil Crusts (BSCs) found in the Gurbantunggut desert. Desiccation tolerance is defined as the ability to revive from the air dried state. To elucidate the molecular mechanisms related to desiccation tolerance, we employ...

journal_title：BMC genomics

authors： Gao B,Zhang D,Li X,Yang H,Zhang Y,Wood AJ

更新日期：2015-05-28 00:00:00

abstract：BACKGROUND:Two fifths of the world's population is at risk from dengue. The absence of effective drugs and vaccines leaves vector control as the primary intervention tool. Understanding dengue virus (DENV) host interactions is essential for the development of novel control strategies. The availability of genome sequenc...

journal_title：BMC genomics

authors： Guo X,Xu Y,Bian G,Pike AD,Xie Y,Xi Z

更新日期：2010-06-16 00:00:00

abstract：BACKGROUND:The approaches for shotgun-based sequencing of vertebrate genomes are now well-established, and have resulted in the generation of numerous draft whole-genome sequence assemblies. In contrast, the process of refining those assemblies to improve contiguity and increase accuracy (known as 'sequence finishing')...

journal_title：BMC genomics

authors： Blakesley RW,Hansen NF,Gupta J,McDowell JC,Maskeri B,Barnabas BB,Brooks SY,Coleman H,Haghighi P,Ho SL,Schandler K,Stantripop S,Vogt JL,Thomas PJ,NISC Comparative Sequencing Program.,Bouffard GG,Green ED

更新日期：2010-01-11 00:00:00

abstract：BACKGROUND:The contribution of a gene to the fitness of a bacterium can be assayed by whether and to what degree the bacterium tolerates transposon insertions in that gene. We use this fact to compare the fitness of syntenic homologous genes among related Salmonella strains and thereby reveal differences not apparent a...

journal_title：BMC genomics

authors： Canals R,Xia XQ,Fronick C,Clifton SW,Ahmer BM,Andrews-Polymenis HL,Porwollik S,McClelland M

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Europeans and American Indians were major genetic ancestry of Hispanics in the U.S. These ancestral groups have markedly different incidence rates and outcomes in many types of cancers. Therefore, the genetic admixture may cause biased genetic association study with cancer susceptibility variants specificall...

journal_title：BMC genomics

authors： Wang LJ,Zhang CW,Su SC,Chen HH,Chiu YC,Lai Z,Bouamar H,Ramirez AG,Cigarroa FG,Sun LZ,Chen Y

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:The study and analysis of gene expression measurements is the primary focus of functional genomics. Once expression data is available, biologists are faced with the task of extracting (new) knowledge associated to the underlying biological phenomenon. Most often, in order to perform this task, biologists exe...

journal_title：BMC genomics

authors： Miyazaki FA,Guardia GD,Vêncio RZ,de Farias CR

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:The Lundehund is a highly specialized breed characterized by a unique flexibility of the joints and polydactyly in all four limbs. The extremely small population size and high inbreeding has promoted a high frequency of diseased dogs affected by the Lundehund syndrome (LS), a severe gastro-enteropathic disea...

journal_title：BMC genomics

authors： Metzger J,Pfahler S,Distl O

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:Although the study of gene regulation via the action of specific microRNAs (miRNAs) has experienced a boom in recent years, the analysis of genome-wide interaction networks among miRNAs and respective targeted mRNAs has lagged behind. MicroRNAs simultaneously target many transcripts and fine-tune the express...

journal_title：BMC genomics

authors： Nunez YO,Truitt JM,Gorini G,Ponomareva ON,Blednov YA,Harris RA,Mayfield RD

更新日期：2013-10-22 00:00:00

abstract：BACKGROUND:Floral transition is a critical event in the life cycle of a flowering plant as it determines its reproductive success. Despite extensive studies of specific genes that regulate this process, the global changes in transcript expression profiles at the point when a vegetative meristem transitions into an infl...

journal_title：BMC genomics

authors： Klepikova AV,Logacheva MD,Dmitriev SE,Penin AA

更新日期：2015-06-18 00:00:00

abstract：BACKGROUND:Human T cell leukemia virus type 1 (HTLV-1) Tax is a potent activator of viral and cellular gene expression that interacts with a number of cellular proteins. Many reports show that Tax is capable of regulating cell cycle progression and apoptosis both positively and negatively. However, it still remains to ...

journal_title：BMC genomics

authors： Arainga M,Murakami H,Aida Y

更新日期：2012-06-22 00:00:00

abstract：BACKGROUND:The hepatitis E virus (HEV) is the causative pathogen of hepatitis E, a global public health concern. HEV comprises 8 genotypes with a wide host range and geographic distribution. This study aims to determine the genetic factors influencing the molecular adaptive changes of HEV open reading frames (ORFs) and...

journal_title：BMC genomics

authors： Baha S,Behloul N,Liu Z,Wei W,Shi R,Meng J

更新日期：2019-10-29 00:00:00

abstract：BACKGROUND:Despite its relevance, almost no studies account for the genetic control in the early stages of tree development, i.e. from germination on. This study seeks to make a quite complete transcriptome for olive development and to elucidate the dynamic regulation of the transcriptomic response during the early-juv...

journal_title：BMC genomics

authors： Jiménez-Ruiz J,de la O Leyva-Pérez M,Vidoy-Mercado I,Barceló A,Luque F

更新日期：2018-11-19 00:00:00

abstract：BACKGROUND:The programmed cell death 2 (Pdcd2) gene on mouse chromosome 17 was evaluated as a member of a highly conserved synteny, a candidate for an imprinted locus, and a candidate for the Hybrid sterility 1 (Hst1) gene. RESULTS:New mouse transcripts were identified at this locus: an alternative Pdcd2 mRNA skipping...

journal_title：BMC genomics

authors： Mihola O,Forejt J,Trachtulec Z

更新日期：2007-01-18 00:00:00

abstract：BACKGROUND:Osteoporosis is a common and debilitating bone disease that is characterised by a low bone mineral density (BMD), a highly heritable trait. Genome-wide association studies (GWAS) have proven to be very successful in identifying common genetic variants associated with BMD adjusted for age, gender and weight, ...

journal_title：BMC genomics

authors： Mullin BH,Walsh JP,Zheng HF,Brown SJ,Surdulescu GL,Curtis C,Breen G,Dudbridge F,Richards JB,Spector TD,Wilson SG

更新日期：2016-02-25 00:00:00

abstract：BACKGROUND:microRNAs (miRNAs) are important regulators of translation and have been implicated in the pathogenesis of a number of cardiovascular diseases, including stroke, and suggested as possible prognostic biomarkers. Our aim was to identify miRNAs that are differentially regulated in cerebral arteries after subara...

journal_title：BMC genomics

authors： Müller AH,Povlsen GK,Bang-Berthelsen CH,Kruse LS,Nielsen J,Warfvinge K,Edvinsson L

更新日期：2015-02-22 00:00:00

abstract：BACKGROUND:The Gram-negative bacterium Chlamydia pneumoniae (Cpn) is the leading intracellular human pathogen responsible for respiratory infections such as pneumonia and bronchitis. Basic and applied research in pathogen biology, especially the elaboration of new mechanism-based anti-pathogen strategies, target discov...

journal_title：BMC genomics

authors： Maier CJ,Maier RH,Virok DP,Maass M,Hintner H,Bauer JW,Onder K

更新日期：2012-11-16 00:00:00

abstract：BACKGROUND:The trypanosomatids Leishmania major, Trypanosoma brucei and Trypanosoma cruzi cause some of the most debilitating diseases of humankind: cutaneous leishmaniasis, African sleeping sickness, and Chagas disease. These protozoa possess complex life cycles that involve development in mammalian and insect hosts, ...

journal_title：BMC genomics

authors： Parsons M,Worthey EA,Ward PN,Mottram JC

更新日期：2005-09-15 00:00:00

abstract：BACKGROUND:Skin and its mucus are known to be the first barrier of defence against any external stressors. In fish, skin wounds frequently appear as a result of intensive culture and also some diseases have skin ulcers as external clinical signs. However, there is no information about the changes produced by the wounds...

journal_title：BMC genomics

authors： Cordero H,Brinchmann MF,Cuesta A,Esteban MA

更新日期：2017-12-02 00:00:00