Renin-producing serous cystoadenocarcinoma of the ovary: a case report.

Abstract:

BACKGROUND:Only a few renin-producing ovarian tumors have been reported, and most such ovarian tumors have been sex cord/stromal tumors. Renin-producing ovarian epithelial tumors are quite rare. CASE:A 46-year-old woman presented with hypertension and hypokalemia. Examinations of the patient revealed elevated plasma renin activity, hyperaldosteronism and a pelvic mass. Subsequently, a right ovarian tumor mass was resected. Microscopic observation of the tumor revealed a well-differentiated serous cystadenocarcinoma. Immediately after surgery, blood pressure, serum potassium, plasma renin activity and plasma aldosterone levels returned to normal ranges. RT-PCR analysis and immunohistochemical staining of this tumor indicated that it was producing renin. CONCLUSION:This is the first report of a renin-producing ovarian serous cystadenocarcinoma.

journal_name

Eur J Gynaecol Oncol

authors

Iwamoto H,Hirata S,Honda T,Fukasawa H,Kimura N,Hoshi K

keywords:

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

183-6

issue

3

eissn

0392-2936

issn

2709-0086

journal_volume

23

pub_type

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