Abstract:
BACKGROUND:Only a few renin-producing ovarian tumors have been reported, and most such ovarian tumors have been sex cord/stromal tumors. Renin-producing ovarian epithelial tumors are quite rare. CASE:A 46-year-old woman presented with hypertension and hypokalemia. Examinations of the patient revealed elevated plasma renin activity, hyperaldosteronism and a pelvic mass. Subsequently, a right ovarian tumor mass was resected. Microscopic observation of the tumor revealed a well-differentiated serous cystadenocarcinoma. Immediately after surgery, blood pressure, serum potassium, plasma renin activity and plasma aldosterone levels returned to normal ranges. RT-PCR analysis and immunohistochemical staining of this tumor indicated that it was producing renin. CONCLUSION:This is the first report of a renin-producing ovarian serous cystadenocarcinoma.
journal_name
Eur J Gynaecol Oncoljournal_title
European journal of gynaecological oncologyauthors
Iwamoto H,Hirata S,Honda T,Fukasawa H,Kimura N,Hoshi Kkeywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
183-6issue
3eissn
0392-2936issn
2709-0086journal_volume
23pub_type
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
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