当前位置： SCI文献检索 > GASTROINTESTINAL ENDOSCOPY期刊下所有文献 > Light-induced autofluorescence spectroscopy for the endoscopic detection of esophageal cancer.

Light-induced autofluorescence spectroscopy for the endoscopic detection of esophageal cancer.

Abstract：

BACKGROUND:Any innovative optical system that facilitates the early endoscopic detection of neoplastic change in the GI mucosa has the potential to greatly improve survival and quality of life for patients prone to have GI malignancies develop. The present article describes light-induced autofluorescence spectroscopy with violet-blue excitation light for in vivo diagnosis of cancerous tissue of the esophagus during routine endoscopy. METHODS:One hundred twenty-nine endogenous fluorescence spectra were obtained from normal mucosa and malignant lesions in 9 patients with squamous cell cancer and 4 with adenocarcinoma of the esophagus. Following spectrographic measurements, biopsy specimens were obtained for definitive classification of the spectra. A special light source capable of delivering either white or violet-blue light for excitation of tissue autofluorescence by means of an endoscope was used. Endogenous fluorescence spectra emitted by tissues were detected with a fiberoptic probe and analyzed with a spectrograph. RESULTS:Squamous cell cancer and adenocarcinoma of the esophagus exhibit specific changes in the emitted fluorescence spectra as compared with normal mucosa. Based on the results obtained in earlier studies, malignant and benign spectra were differentiated with the aid of a mathematical algorithm. By using this algorithm, a sensitivity of 97% and specificity of 95% were obtained for the diagnosis of esophageal carcinoma. CONCLUSIONS:Light-induced fluorescence spectroscopy is useful for the endoscopic detection of squamous cell cancer and adenocarcinoma of the esophagus. This spectroscopic study provides a basis for the design of a simplified autofluorescence imaging system for detection of esophageal neoplasms.

journal_name

Gastrointest Endosc

journal_title

Gastrointestinal endoscopy

authors

Mayinger B,Horner P,Jordan M,Gerlach C,Horbach T,Hohenberger W,Hahn EG

doi

10.1067/mge.2001.116563

keywords:

subject

Has Abstract

pub_date

2001-08-01 00:00:00

pages

195-201

issue

2

eissn

0016-5107

issn

1097-6779

pii

S0016-5107(01)70106-X

journal_volume

54

pub_type

杂志文章

相关文献

GASTROINTESTINAL ENDOSCOPY文献大全
  • A comparison of magnifying and nonmagnifying colonoscopy for diagnosis of colorectal polyps: A prospective study.

    abstract：BACKGROUND:Discrimination between neoplastic and non-neoplastic colorectal polyps is essential for determining appropriate treatment. The mucosal crypt pattern of polyps can be observed with a nonmagnifying colonoscope; however, mucosal crypt patterns are better seen by magnifying colonoscopy, which can also be a nonin...

    journal_title：Gastrointestinal endoscopy

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1067/mge.2003.31

    authors： Konishi K,Kaneko K,Kurahashi T,Yamamoto T,Kushima M,Kanda A,Tajiri H,Mitamura K

    更新日期：2003-01-01 00:00:00

  • Multiple endoscopic biopsies in research subjects: safety results from a National Institutes of Health series.

    abstract：BACKGROUND:Routine endoscopic mucosal biopsies are generally considered safe. However, the outcomes of performing large numbers of biopsies in subjects enrolled in research protocols have not been reported. OBJECTIVE:Our purpose was to assess the safety of taking numerous mucosal biopsy specimens during endoscopic pro...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/j.gie.2008.05.015

    authors： Yao MD,von Rosenvinge EC,Groden C,Mannon PJ

    更新日期：2009-04-01 00:00:00

  • Clinical prediction rule to determine the need for repeat ERCP after endoscopic treatment of postsurgical bile leaks.

    abstract：BACKGROUND AND AIMS:In patients who have undergone ERCP with biliary stenting for postsurgical bile leaks, the optimal method (ERCP or gastroscopy) and timing of stent removal is controversial. We developed a clinical prediction rule to identify cases in which a repeat ERCP is unnecessary. METHODS:Population-based stu...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/j.gie.2016.10.027

    authors： Tsolakis AV,James PD,Kaplan GG,Myers RP,Hubbard J,Wilson T,Zimmer S,Mohamed R,Cole M,Bass S,Swain MG,Heitman SJ

    更新日期：2017-05-01 00:00:00

  • Clear liquid diet before bowel preparation predicts successful chromoendoscopy in patients with inflammatory bowel disease.

    abstract：BACKGROUND AND AIMS:Chromoendoscopy (CE) has been shown to generate both a superior diagnostic yield and dysplasia detection rate than conventional white-light endoscopy and requires a high-quality bowel preparation. The aim of this study was to identify predictors of the ability to perform CE in patients with inflamma...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/j.gie.2018.09.039

    authors： Megna B,Weiss J,Ley D,Saha S,Pfau P,Grimes I,Li Z,Caldera F

    更新日期：2019-02-01 00:00:00

  • Neoplasms arising in large gastric hyperplastic polyps: endoscopic and pathologic features.

    abstract：BACKGROUND:Little is known about gastric neoplasms arising from hyperplastic polyps (HPs). OBJECTIVE:To investigate the risk factors associated with neoplasms within HPs and to evaluate the role of alterations of the p16-cyclin D1-pRb pathway in the malignant transformation of HPs. DESIGN:Retrospective, case-control ...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/j.gie.2014.04.020

    authors： Ahn JY,Son DH,Choi KD,Roh J,Lim H,Choi KS,Lee JH,Kim DH,Song HJ,Lee GH,Jung HY,Kim JH,Han S,Park YS

    更新日期：2014-12-01 00:00:00

  • Percutaneous cholangioscopic or transpapillary insertion of self-expanding biliary metal stents.

    abstract：:Fifty-two self-expanding metal stents were implanted in 39 patients with malignant (35 patients) or benign (4 patients) biliary stenoses. The stents were inserted and properly released by means of a 7 or 9 French gauge delivery catheter via the percutaneous (20 patients) or transpapillary (19 patients) route. In all c...

    journal_title：Gastrointestinal endoscopy

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0016-5107(91)70617-2

    authors： Neuhaus H,Hagenmüller F,Griebel M,Classen M

    更新日期：1991-01-01 00:00:00

  • Improvement of children's nutritional status after enteral feeding by PEG: an interim report.

    abstract：BACKGROUND:Enteral feeding by percutaneous endoscopic gastrostomy is indicated as long-term nutritional support for children with neurologic impairment and dysphagia. We report our experience with percutaneous endoscopic gastrostomy and evaluate the age range of children with cerebral palsy who benefit most with weight...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/s0016-5107(99)70222-1

    authors： Brant CQ,Stanich P,Ferrari AP Jr

    更新日期：1999-08-01 00:00:00

  • Evaluation of the clinical efficacy of colon capsule endoscopy in the detection of lesions of the colon: prospective, multicenter, open study.

    abstract：BACKGROUND:Colon capsule endoscopy (CCE) is a new procedure for colon imaging. Limited information is available regarding visualization of flat colon lesions and patient acceptability in Japan. OBJECTIVE:The aims of this study were to evaluate the sensitivity of CCE in detecting polyps and other lesions compared with ...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.gie.2015.02.004

    authors： Saito Y,Saito S,Oka S,Kakugawa Y,Matsumoto M,Aihara H,Watari I,Aoyama T,Nouda S,Kuramoto T,Watanabe K,Ohmiya N,Higuchi K,Goto H,Arakawa T,Tanaka S,Tajiri H

    更新日期：2015-11-01 00:00:00

  • Brush cytology during ERCP for the diagnosis of biliary and pancreatic malignancies.

    abstract：:Endoscopic retrograde cholangiopancreatography is a valuable tool in the diagnosis and management of pancreaticobiliary diseases. The diagnostic sensitivity of brush cytology is reported as between 18% and 70% for malignant bile duct or pancreatic duct strictures. We report our findings in 74 patients with pancreatico...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/s0016-5107(94)70155-5

    authors： Ferrari Júnior AP,Lichtenstein DR,Slivka A,Chang C,Carr-Locke DL

    更新日期：1994-03-01 00:00:00

  • Cutting the defiant lower esophageal ring.

    abstract：:A symptomatic lower esophageal ring generally responds to standard bougienage therapy. However, a subset of patients with a lower esophageal ring defy dilation therapy. We have evaluated the efficacy of electrocautery incision of "defiant" lower esophageal rings, the data of which forms the basis of this report. Seven...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/s0016-5107(93)70210-2

    authors： Burdick JS,Venu RP,Hogan WJ

    更新日期：1993-09-01 00:00:00

  • Novel ex vivo model for hands-on teaching of and training in EUS-guided biliary drainage: creation of "Mumbai EUS" stereolithography/3D printing bile duct prototype (with videos).

    abstract：BACKGROUND:EUS-guided biliary drainage (EUS-BD) has emerged as an alternative rescue method in patients with failed ERCP. Opportunities for teaching and training are limited because of a low case volume at most centers. OBJECTIVE:To evaluate a stereolithography/3-dimensional (3D) printing bile duct prototype for teach...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/j.gie.2014.09.011

    authors： Dhir V,Itoi T,Fockens P,Perez-Miranda M,Khashab MA,Seo DW,Yang AM,Lawrence KY,Maydeo A

    更新日期：2015-02-01 00:00:00

  • Experimental studies of transgastric gallbladder surgery: cholecystectomy and cholecystogastric anastomosis (videos).

    abstract：BACKGROUND:Transgastric flexible endoscopic surgery might offer advantages over open and laparoscopic surgery. The aim of this study was to develop methods for performing transgastric biliary endosurgery. METHODS:Cholecystectomies and biliary anastomoses were performed in 8 anesthetized pigs (27-30 kg) in nonsurvival ...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/s0016-5107(04)02774-9

    authors： Park PO,Bergström M,Ikeda K,Fritscher-Ravens A,Swain P

    更新日期：2005-04-01 00:00:00

  • Endoscopic resection of benign tumors of the duodenal papilla without and with intraductal growth.

    abstract：BACKGROUND:Endoscopic papillectomy of benign papillary tumor is still not widely practiced. Intraductal growth has been considered a contraindication for endoscopic therapy. This prospective study evaluates endoscopic papillectomy for treatment of benign papillary tumors without and with intraductal growth. METHODS:Mo...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/j.gie.2005.04.053

    authors： Bohnacker S,Seitz U,Nguyen D,Thonke F,Seewald S,deWeerth A,Ponnudurai R,Omar S,Soehendra N

    更新日期：2005-10-01 00:00:00

  • Methylene blue staining for intestinal metaplasia of the gastric cardia with follow-up for dysplasia.

    abstract：BACKGROUND:Previous studies by our group have identified a 23% prevalence of intestinal metaplasia involving the gastric cardia in patients undergoing elective esophagogastroduodenoscopy (EGD). The current study evaluates the potential clinical utility of vital staining with methylene blue for detecting intestinal meta...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/s0016-5107(98)70124-5

    authors： Morales TG,Bhattacharyya A,Camargo E,Johnson C,Sampliner RE

    更新日期：1998-07-01 00:00:00

  • Transgastric ventral hernia repair: a controlled study in a live porcine model (with videos).

    abstract：BACKGROUND:Ventral hernia repair is currently performed via open surgery or laparoscopic approach. OBJECTIVE:To develop an alternative ventral hernia repair technique. SETTING:Acute and survival experiments on twelve 50-kg pigs. DESIGN AND INTERVENTIONS:An endoscope was introduced transgastrically into the peritonea...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/j.gie.2008.04.014

    authors： Kantsevoy SV,Dray X,Shin EJ,Buscaglia JM,Magno P,Assumpcao L,Marohn MR,Redan J,Giday SA,Schweitzer MA,Apollo Group.

    更新日期：2009-01-01 00:00:00

  • A randomized controlled trial of pentoxifylline for the prevention of post-ERCP pancreatitis.

    abstract：BACKGROUND:Pentoxifylline can ameliorate pancreatitis in animal models because of its anti-tumor necrosis factor properties. OBJECTIVE:Our purpose was to study the safety and efficacy of pentoxifylline in the prevention of post-ERCP pancreatitis. DESIGN:Patients due to undergo ERCP for various indications were random...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.gie.2007.03.1045

    authors： Kapetanos D,Kokozidis G,Christodoulou D,Mistakidis K,Sigounas D,Dimakopoulos K,Kitis G,Tsianos EV

    更新日期：2007-09-01 00:00:00

  • Management of code status in the periendoscopic period: a national survey of current practices and beliefs of U.S. gastroenterologists.

    abstract：BACKGROUND AND AIMS:This study aims to assess current practices and perspectives of gastroenterologists on approaches to code status before inpatient endoscopy. METHODS:Self-reported data were obtained through a voluntary, anonymous survey of gastroenterologists and gastroenterology trainees in the United States (U.S....

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/j.gie.2021.01.005

    authors： Feld LD,Mergener K,Rubin DT,Rao VL

    更新日期：2021-01-18 00:00:00

  • Self-approximating transluminal access technique for natural orifice transluminal endoscopic surgery: a porcine survival study (with video).

    abstract：BACKGROUND:The ability to access the abdominal cavity though a direct (modified-PEG type) gastric incision to perform natural orifice transluminal endoscopic surgery (NOTES) has been demonstrated in the literature. However, the optimal technique to access the abdomen remains unknown. OBJECTIVE:The aim of this study wa...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/j.gie.2007.09.023

    authors： Pauli EM,Moyer MT,Haluck RS,Mathew A

    更新日期：2008-04-01 00:00:00

  • Computer-aided detection-assisted colonoscopy: classification and relevance of false positives.

    abstract：BACKGROUND AND AIMS:False positive (FP) results by computer-aided detection (CADe) hamper the efficiency of colonoscopy by extending examination time. Our aim was to develop a classification of the causes and clinical relevance of CADe FPs, and to assess the relative distribution of FPs in a real-life setting. METHODS...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/j.gie.2020.06.021

    authors： Hassan C,Badalamenti M,Maselli R,Correale L,Iannone A,Radaelli F,Rondonotti E,Ferrara E,Spadaccini M,Alkandari A,Fugazza A,Anderloni A,Galtieri PA,Pellegatta G,Carrara S,Di Leo M,Craviotto V,Lamonaca L,Lorenzetti R,

    更新日期：2020-10-01 00:00:00

  • Early colonoscopy for acute lower GI bleeding predicts shorter hospital stay: a retrospective study of experience in a single center.

    abstract：BACKGROUND:Appropriate management of lower-GI hemorrhage remains controversial largely because outcomes data are lacking. It is our hypothesis that clinical factors, such as comorbidity, hemodynamic instability, and timing of colonoscopy, are associated with hospital lengths of stay. METHODS:Medical records of patient...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/s0016-5107(03)02304-6

    authors： Schmulewitz N,Fisher DA,Rockey DC

    更新日期：2003-12-01 00:00:00

  • Argon beam coagulation for treatment of symptomatic radiation-induced proctitis.

    abstract：BACKGROUND:Radiation proctitis is a complication of radiotherapy for malignant pelvic disease. Argon beam coagulation is a new and rapidly evolving technology that permits a "no-touch" electrocoagulation of diseased tissue. METHODS:We analyzed retrospectively the records of 7 patients with prostatic and endometrial ca...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/s0016-5107(99)70054-4

    authors： Fantin AC,Binek J,Suter WR,Meyenberger C

    更新日期：1999-04-01 00:00:00

  • Nitrous oxide for colonoscopy: a randomized controlled study.

    abstract：BACKGROUND:Intravenous sedation/analgesia for colonoscopy is accompanied with certain risks and postprocedure drowsiness. We sought to determine whether inhaled nitrous oxide (Entonox: 50% nitrous oxide, 50% oxygen) provides adequate analgesia for colonoscopy and the impact of this agent on recovery. METHODS:All patie...

    journal_title：Gastrointestinal endoscopy

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0016-5107(00)70354-3

    authors： Forbes GM,Collins BJ

    更新日期：2000-03-01 00:00:00

  • Holmium laser lithotripsy under direct peroral cholangioscopy by using an ultra-slim upper endoscope for patients with retained bile duct stones (with video).

    abstract：BACKGROUND:Direct peroral cholangioscopy (POC) by using an ultra-slim endoscope provides direct visualization of the bile duct and allows for therapeutic intervention. Holmium laser lithotripsy can be effective for retained bile duct stones, but it requires direct visualization during the procedure for safe and effecti...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/j.gie.2011.07.027

    authors： Kim HI,Moon JH,Choi HJ,Lee JC,Ahn HS,Song AR,Lee TH,Cho YD,Park SH,Kim SJ

    更新日期：2011-11-01 00:00:00

  • Snare cautery debridement prior to Nd:YAG photoablation improves treatment efficiency of broad-based adenomas of the colorectum.

    abstract：:Forty-six patients who underwent piecemeal resection of large, sessile villous adenomas followed by immediate laser photoablative therapy are presented. In contrast to previously published series utilizing laser alone, prior snare resection of such lesions provides copious tissue for histologic analysis, decreases the...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/s0016-5107(89)72793-0

    authors： Low DE,Kozarek RA

    更新日期：1989-07-01 00:00:00

  • Optimization of light dosimetry for photodynamic therapy of Barrett's esophagus: efficacy vs. incidence of stricture after treatment.

    abstract：BACKGROUND:Photodynamic therapy (PDT) may be used to ablate high-grade dysplasia/early stage cancer (HGD/T1) in patients with Barrett's esophagus. PDT may result in esophageal stricture. This nonrandomized, unblinded, dose de-escalation study in consecutive patients was designed to determine the lowest light dose effec...

    journal_title：Gastrointestinal endoscopy

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0016-5107(04)02394-6

    authors： Panjehpour M,Overholt BF,Phan MN,Haydek JM

    更新日期：2005-01-01 00:00:00

  • Treatment of symptomatic distal common bile duct stenosis secondary to chronic pancreatitis: comparison of single vs. multiple simultaneous stents.

    abstract：BACKGROUND:Common bile duct stenosis occurs in up to 30% of patients with chronic pancreatitis. Most such stenoses are found incidentally during ERCP, but others manifest as obstructive jaundice, recurrent cholangitis, secondary biliary cirrhosis, or choledocholithiasis. Operative drainage has been the main treatment d...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/s0016-5107(04)02275-8

    authors： Catalano MF,Linder JD,George S,Alcocer E,Geenen JE

    更新日期：2004-12-01 00:00:00

  • The natural history of untreated duodenal and ampullary adenomas in patients with familial adenomatous polyposis followed in an endoscopic surveillance program.

    abstract：BACKGROUND:Endoscopic surveillance is recommended for patients with familial adenomatous polyposis (FAP) because of the high prevalence of duodenal adenomas and the risk of periampullary cancer. The aim of this study was to assess the natural history of untreated duodenal and ampullary adenomas in FAP patients during s...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/s0016-5107(99)70013-1

    authors： Burke CA,Beck GJ,Church JM,van Stolk RU

    更新日期：1999-03-01 00:00:00

  • Digital, single-operator cholangiopancreatoscopy in the diagnosis and management of pancreatobiliary disorders: a multicenter clinical experience (with video).

    abstract：BACKGROUND AND AIMS:Digital cholangioscopes provide higher-resolution imaging of the pancreatobiliary tract compared with fiberoptic instruments. The role of a new, digital, single-operator cholangiopancreatoscopy (SOC) system for diagnosis and treatment of pancreatobiliary disorders in clinical practice is not known. ...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.gie.2016.03.789

    authors： Navaneethan U,Hasan MK,Kommaraju K,Zhu X,Hebert-Magee S,Hawes RH,Vargo JJ,Varadarajulu S,Parsi MA

    更新日期：2016-10-01 00:00:00

  • Inspection of the human stomach using remote-controlled capsule endoscopy: a feasibility study in healthy volunteers (with videos).

    abstract：BACKGROUND:Remote control of capsule endoscopes might allow reliable inspection of the human stomach. OBJECTIVE:To assess the safety and efficacy of manipulation of a modified capsule endoscope with magnetic material (magnetic maneuverable capsule [MMC]) in the human stomach by using a handheld external magnet. DESIG...

    journal_title：Gastrointestinal endoscopy

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.gie.2010.08.053

    authors： Keller J,Fibbe C,Volke F,Gerber J,Mosse AC,Reimann-Zawadzki M,Rabinovitz E,Layer P,Schmitt D,Andresen V,Rosien U,Swain P

    更新日期：2011-01-01 00:00:00

  • An improved technique for accessory papilla cannulation in pancreas divisum.

    abstract：:Cannulation of the accessory papilla with dorsal pancreas ductography was accomplished in 13 of 15 consecutive cases of pancreas divisum. When routine cannulation of the main pancreatic papilla fails to produce a pancreatogram or yields only a ventral pancreas, the use of intravenous secretin and a 23-gauge needle cat...

    journal_title：Gastrointestinal endoscopy

    pub_type： 杂志文章

    doi：10.1016/s0016-5107(85)71956-6

    authors： O'Connor KW,Lehman GA

    更新日期：1985-02-01 00:00:00