Abstract:
:A dinucleoside monophosphate, 6,2'-anhydro-6-oxy-1-beta-D-arabinofuranosyluracil-phosphoryl- (3'-5')-6,2'-anhydro-6-oxy-1-beta-D-arabinofuranosyluracil (I) was synthesized by the condensation reaction using DCC from 5'-monomethoxytrityl derivative(VII) and 3'-acetyl-5'-phosphate(X) of the monomer units. Yield was ca. 70%. UV of compound I showed no hypochromicity and its CD spectrum showed only a trough at 252 nm. No temperature dependency of epsilon and [Q] values was observed. These results suggested an unstacked random conformation for I. Complex formation of I with cycloadenosine oligomer could not be detected under the experimental condition.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Ikehara M,Tezuka Tdoi
10.1093/nar/1.3.479keywords:
subject
Has Abstractpub_date
1974-03-01 00:00:00pages
479-89issue
3eissn
0305-1048issn
1362-4962journal_volume
1pub_type
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