[Endothelial dysfunction in patients with acute coronary syndrome].

Abstract:

:Increased vasoconstriction, activation of platelet vessel wall interaction and invasion of monocytes into the subintima as well as vascular smooth muscle cell proliferation play a fundamental role in the pathogenesis of coronary artery disease. Acute coronary syndromes such as myocardial infarction and unstable angina pectoris are characterized by plaque rupture or erosion, activation of platelets and the coagulation system and vasoconstriction. Endothelial dysfunction may be one of the underlying mechanisms linking coronary artery disease and acute coronary syndromes. Both of these are often temporarily limited. Therefore, "non-invasive examination" of endothelial function by venous occlusion plethysmography or high resolution ultrasound might be useful for monitoring high-risk patients.

journal_name

Herz

journal_title

Herz

authors

Fichtlscherer S,Zeiher AM

doi

10.1007/BF03044225

keywords:

subject

Has Abstract

pub_date

1999-11-01 00:00:00

pages

534-43

issue

7

eissn

0340-9937

issn

1615-6692

journal_volume

24

pub_type

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