当前位置： SCI文献检索 > SPINE期刊下所有文献 > Randomized trial of radiofrequency lumbar facet denervation for chronic low back pain.

Randomized trial of radiofrequency lumbar facet denervation for chronic low back pain.

Abstract：

STUDY DESIGN:A prospective double-blind randomized trial in 31 patients. OBJECTIVES:To assess the clinical efficacy of percutaneous radiofrequency denervation of the lumbar zygapophysial joints in reducing pain, functional disability, and physical impairment in patients with back pain originating from the lumbar zygapophysial joints. SUMMARY OF BACKGROUND DATA:Chronic low back pain is a major health problem in the industrialized world. A treatment option is percutaneous radiofrequency denervation of the lumbar zygapophysial joints. Its clinical efficacy has never been formally tested in a controlled trial. METHODS:Thirty-one patients with a history of at least 1 year of chronic low back pain were selected on the basis of a positive response to a diagnostic nerve blockade and subsequently randomly assigned to one of two treatment groups. Each patient in the radiofrequency treatment group (15 patients) received an 80 C radiofrequency lesion of the dorsal ramus of the segmental nerve roots L3, L4, and L5. Patients in the control group (n = 16) underwent an the same procedure but without use of a radiofrequency current. Both the treating physician and the patients were blinded to the group assignment. Before treatment, physical impairment, rating of pain, the degree of disability, and quality of life were assessed by a blinded investigator. RESULTS:Eight weeks after treatment, there were 10 success patients in the radiofrequency group (n = 15) and 6 in the sham group (n = 16). The unadjusted odds ratio was 3.3 (P = 0.05, not significant), and the adjusted odds ratio was 4.8 (P < 0.05, significant). The differences in effect on the visual analog scale scores, global perceived effect, and the Oswestry disability scale were statistically significant. Three, 6, and 12 months after treatment, there were significantly more success patients in the radiofrequency group compared with the sham group. CONCLUSIONS:Radiofrequency lumbar zygapophysial joint denervation results in a significant alleviation of pain and functional disability in a select group of patients with chronic low back pain, both on a short-term and a long-term basis.

journal_name

Spine (Phila Pa 1976)

journal_title

Spine

authors

van Kleef M,Barendse GA,Kessels A,Voets HM,Weber WE,de Lange S

doi

10.1097/00007632-199909150-00013

keywords:

subject

Has Abstract

pub_date

1999-09-15 00:00:00

pages

1937-42

issue

eissn

0362-2436

issn

1528-1159

journal_volume

pub_type

临床试验,杂志文章,随机对照试验

在线工具

Randomized trial of radiofrequency lumbar facet denervation for chronic low back pain.