Abstract：
:The aim of the present study was to evaluate some of the factors which may influence the reliability of nasal NO measurements, and to optimize methods suitable for children and adults. Nasal nitric oxide (NO) output was determined by chemiluminescent analysis of aspirated samples in 16 adults and 6 children. With the velopharyngeal aperture closed, stable NO levels were obtained at flows ranging form 0.9 to 6.2 L/min. NO output averaged 401.0 +/- 145.4 nL/min./M2 in 6 children, 338.2 +/- 92.3 in 7 adult females and 268.6 +/- 70.2 in 9 adult males. Nasal NO output was independent of flow provided a stable plateau of NO value was reached. In this study, the optimal range of flows was 3.2-5.2 L/min. in adults and 2.2-3.2 L/min. in children. This enables selection of the most favorable flow to be chosen for individual subjects and situations.
journal_name
Rhinologyjournal_title
Rhinologyauthors
Qian W,Djupesland PG,Chatkin JM,McClean P,Furlott H,Chapnik JS,Zamel N,Haight JSkeywords:
subject
Has Abstractpub_date
1999-06-01 00:00:00pages
61-5issue
2eissn
0300-0729issn
1996-8604journal_volume
37pub_type
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