Abstract：
:Acute pancreatic hormonal responses to oral glucose loads were investigated in garden warblers during the prolonged fast that follows their autumnal migratory fattening. Plasma glucose, free fatty acids, beta-hydroxybutyrate, insulin (INS), and glucagon (GLN) were measured prior to and 10 min after an oral glucose load in three groups of birds: One had food ad libitum, and the other two were either food restricted or food deprived down to a given (low) body mass level. Ten minutes after the glucose load, plasma glucose levels increased significantly in all three groups (range of mean values: basal, 15.1-16.0; glucose-stimulated, 19.1-23.7 mmol/L). A smaller increase in food-restricted/deprived groups was not statistically significant. Free fatty acid levels (1.0-1.5 mmol/L) after 10 min were unchanged, while beta-hydroxybutyrate decreased to similar levels in food-restricted/deprived and control groups (basal, 3.3-4.2; glucose-stimulated, 1.9-2.4 mmol/L). Insulin increased and glucagon decreased in response to oral glucose loads. However, initial levels and responses of plasma insulin to glucose were lower, and those of glucagon were higher in the food-restricted/deprived groups (INS, both 2.7; DeltaINS, 0.1-0.3 mIU/L; GLN, 2.8-3.3; DeltaGLN, 1.4-2.2 microg/L) than in the control group (means +/- SE; INS, 3.8 +/- 0.8; DeltaINS, 1.4 +/- 0.7 mIU/L; GLN, 2.5 +/- 0.5; DeltaGLN, 0.7 +/- 0.5 microg/L), resulting in similar increases in the insulin:glucagon ratio. Impaired insulin secretion may thus be compensated for by a greater glucagon response and the decreased glucose utilization rates of fasting garden warblers may result from insulin resistance and/or delayed glucose absorption.
journal_name
Gen Comp Endocrinoljournal_title
General and comparative endocrinologyauthors
Totzke U,Hübinger A,Korthaus G,Bairlein Fdoi
10.1006/gcen.1999.7295keywords:
subject
Has Abstractpub_date
1999-07-01 00:00:00pages
116-21issue
1eissn
0016-6480issn
1095-6840pii
S0016-6480(99)97295-7journal_volume
115pub_type
杂志文章abstract：:In adult domestic fowl, angiotensin (ANG) receptors are present in the vascular smooth muscles (VSM) and in the endothelium, mediating vasorelaxation via endothelium-derived relaxing factor/cGMP. ANG II-induced relaxation is minor in chicks and becomes more marked as they mature but diminishes in adult birds, whereas ...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.1998.7150
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/0016-6480(86)90028-6
更新日期：1986-10-01 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2013.02.042
更新日期：2013-06-01 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/0016-6480(88)90037-8
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
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更新日期：2014-01-01 00:00:00
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journal_title：General and comparative endocrinology
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.1993.1146
更新日期：1993-10-01 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/0016-6480(87)90120-1
更新日期：1987-03-01 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章,评审
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2009.04.028
更新日期：2009-09-15 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2019.113224
更新日期：2019-11-01 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2006.03.016
更新日期：2006-09-15 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章,评审
doi：10.1016/j.ygcen.2015.09.009
更新日期：2016-02-01 00:00:00
abstract：:Insulin (INS) plays a critical role in the growth, development, and metabolism of vertebrates. In this study, a cDNA encoding a novel insulin receptor (IR) subtype was isolated, cloned, and sequenced from the liver of rainbow trout. A 1525-bp cDNA encoding a partial amino acid sequence of the β-subunit including the t...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2010.09.005
更新日期：2010-12-01 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.1994.1160
更新日期：1994-10-01 00:00:00
abstract：:The arginine vasotocin/vasopressin (AVT/AVP) and gonadotropin releasing hormone (GnRH) systems are known to control sexual behaviors and reproduction, respectively, in different vertebrate groups. However, a direct functional connection between these two neuroendocrine systems has not been demonstrated for any vertebr...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2015.07.013
更新日期：2016-01-01 00:00:00
abstract：:Sexual dimorphism in prenatal development is widespread among vertebrates, including birds. Its mechanism remains unclear, although it has been attributed to the effect of maternal steroid hormones. The aim of this study was to investigate how increased levels of steroid hormones in the eggs influence early embryonic ...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2017.09.004
更新日期：2017-12-01 00:00:00
abstract：:Follicle-stimulating hormone (FSH) stimulates aromatase activity of immature rat Sertoli cells cultured in vitro in the presence of an androgen substrate, a phenomenon that can be used to measure FSH bioactivity. This paper analyzes the effects of sera from various animal species on both aromatase activity and morphol...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.1994.1106
更新日期：1994-07-01 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/0016-6480(88)90290-0
更新日期：1988-07-01 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2006.08.010
更新日期：2007-01-15 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.1996.0067
更新日期：1996-05-01 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2014.04.024
更新日期：2014-08-01 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2010.10.011
更新日期：2011-01-15 00:00:00
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journal_title：General and comparative endocrinology
pub_type： 杂志文章
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更新日期：2001-02-01 00:00:00
abstract：:We isolated and cloned full-length cDNAs of transthyretin (TTR) from 2 genera of lamprey, Petromyzon marinus and Lampetra appendix. These sequences represent the first report of TTR sequences in vertebrates basal to teleost fishes. The deduced amino acid sequence of lamprey TTR cDNAs showed 36-47% identity with those ...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1016/j.ygcen.2006.11.017
更新日期：2007-03-01 00:00:00
abstract：:The first studies that identified leptin and its receptor (LepR) in mammals were based on mutant animals that displayed dramatic changes in body-weight and regulation of energy homeostasis. Subsequent studies have shown that a deficiency of leptin or LepR in homoeothermic mammals results in hyperphagia, obesity, infer...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：
更新日期：2014-01-01 00:00:00
abstract：:Gonadotropin-releasing hormone (GnRH) of vertebrates is now believed to have multiple functions in addition to its role as a hypophysiotropic hormone, as originally defined. Recently, it has been shown that GnRH occurs also in the ascidians, which are considered ancestral chordates. Here the author shows that GnRH ind...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.2001.7728
更新日期：2001-12-01 00:00:00
abstract：:The recent purification of two gonadotropins, GTH I and GTH II, in teleost fish and the development of their specific radioimmunoassays using antibodies directed against their beta subunits have demonstrated that earlier assays for GTH II also measured GTH I. Most of the results on the gonadotropic control of reproduc...
journal_title：General and comparative endocrinology
pub_type： 杂志文章
doi：10.1006/gcen.1998.7088
更新日期：1998-07-01 00:00:00
