Abstract：
UNLABELLED:The aim of the present study was to compare partial deletions of the complement C4 gene in victims of totally unexplained sudden infant death (SID) (n = 89) and borderline SID (n = 15) with and without slight infections prior to death, in cases of infectious death (n = 19), and in living infants with and without infections (n = 84). The SID and borderline SID groups were pooled. In this total SID group slight infections prior to death was associated with deletion of either the C4A or the C4B gene (P = 0.033), and the SID victims with such infections had a higher deletion frequency than the controls (P = 0.039). There were no differences between the living infants with and without upper airway infections. CONCLUSION:The present study confirms that partial deletions of the C4 gene in combination with slight upper airway infections may be a risk factor in sudden infant death.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Opdal SH,Vege A,Stave AK,Rognum TOdoi
10.1007/s004310051051keywords:
subject
Has Abstractpub_date
1999-03-01 00:00:00pages
210-2issue
3eissn
0340-6199issn
1432-1076journal_volume
158pub_type
杂志文章abstract：UNLABELLED:The aim of this study was to assess whether the severity of congenital heart defects (CHD) affects disease-specific health-related quality of life (HRQOL) in children after open heart surgery. One hundred and fourteen children with CHD and one of their parents participated in the study. HRQOL was evaluated b...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-009-1060-7
更新日期：2010-03-01 00:00:00
abstract：:The United Nations Convention of Children's Rights (UNCRC) introduced in 1989 has generated a global movement for the protection of children's rights and has brought about a paradigm change in how children are perceived. Pediatric healthcare professionals are interacting with children and therefore with children's rig...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
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journal_title：European journal of pediatrics
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更新日期：2007-10-01 00:00:00
abstract：:Until recently, trisomy 18 was considered a disease incompatible with life, with a high percentage of electively terminated pregnancies. The usual behavior was denial of treatment. But some medical interventions have changed the survival of children. A search for articles published in the PubMed database on the latest...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01955928
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abstract：:An infant girl three weeks of age with the leading symptom of skin haemorrhages is presented. On further investigation, the signs of severe hepatic damage with hypofibrinogenaemia and prothrombin complex impairment, and renal tubular dysfunction were disclosed. All these pathological symptoms, which were reversed on f...
journal_title：European journal of pediatrics
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doi：10.1007/BF00465567
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journal_title：European journal of pediatrics
pub_type： 杂志文章
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更新日期：1996-07-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-014-2282-x
更新日期：2014-08-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
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journal_title：European journal of pediatrics
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journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
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更新日期：1997-09-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
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更新日期：1999-11-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00431-019-03457-x
更新日期：2019-10-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00447379
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01957752
更新日期：1992-07-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-011-1410-0
更新日期：2011-08-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-018-3232-9
更新日期：2018-11-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
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journal_title：European journal of pediatrics
pub_type： 杂志文章
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journal_title：European journal of pediatrics
pub_type： 杂志文章
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journal_title：European journal of pediatrics
pub_type： 杂志文章
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journal_title：European journal of pediatrics
pub_type： 杂志文章
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更新日期：2003-11-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-005-0002-2
更新日期：2006-02-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-012-1715-7
更新日期：2012-08-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
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journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00595907
更新日期：1989-02-01 00:00:00
abstract：:Iodine deficiency is well documented in Belgium in adults including pregnant women, adolescents, schoolchildren, and neonates, but no data are available in the age group 6 months-3 years. We investigated the status of iodine nutrition in 111 healthy subjects in this age group in an attempt to evaluate the risk of brai...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310000707
更新日期：2001-04-01 00:00:00
