Abstract：
:Background: Pertussis is a highly contagious infectious disease which continues to be an important public-health issue despite the high immunization coverage rates achieved. However, evidence of increased circulation of pertussis among adolescents and adults due to waning immunity and atypical clinical manifestations seem to be the main reasons for its resurgence. The aim of this study was the analysis of the epidemiological trend for pertussis-related hospitalizations in Italy, in relation with vaccination coverage and information from laboratory confirmed cases of pertussis.Methods: A retrospective observational study investigating hospitalizations for pertussis from 2002 to 2016 in Italy was conducted. Frequencies and rates of hospitalization were analyzed and hospitalization data were compared with a series of already published laboratory confirmed data. Results: This study highlighted a rising trend for pertussis hospitalizations in Italy since 2008. Infants aged <1 year showed the highest frequencies (63.39%) and average rates (74.60 × 100000 infants) of hospitalization despite an extremely high vaccination coverage (95.89%). An increasing trend of hospitalization frequency emerged for the age group with levels of IgG antibodies to pertussis toxin compatible with pertussis infection within the last year (20-29 years old age group). Conclusions: The rising trend for pertussis hospitalizations and the greater involvement of infants aged <1 year require an integrated approach, including the implementation of booster doses administration in adolescence and adulthood, the vaccination of pregnant women and the cocoon strategy.
journal_name
Int J Environ Res Public Healthauthors
Fiasca F,Gabutti G,Mattei Adoi
10.3390/ijerph16224531subject
Has Abstractpub_date
2019-11-15 00:00:00issue
22eissn
1661-7827issn
1660-4601pii
ijerph16224531journal_volume
16pub_type
杂志文章abstract：:Lubricating oils used in machines with an open cutting system, such as a saw or harvester, are applied in forest areas, gardening, in the household, and in urban greenery. During the operation of the device with an open cutting system, the lubricating oil is emitted into the environment. Therefore, the use of an oil b...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章,评审
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更新日期：2019-08-20 00:00:00
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journal_title：International journal of environmental research and public health
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更新日期：2019-08-06 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2020-04-14 00:00:00
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更新日期：2019-08-30 00:00:00
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更新日期：2019-08-30 00:00:00
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pub_type： 杂志文章
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pub_type： 社论
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