Melanotic Xp11-associated tumor of the sigmoid colon: A case report.


BACKGROUND:Melanotic Xp11-associated tumors are rare mesenchymal-derived tumors. So far, most primary melanotic Xp11-associated tumors have been reported in the kidney, and reports of this tumor in the gastrointestinal tract are rare. CASE SUMMARY:Here we describe the case of a 25-year-old woman who presented with a melanotic Xp11-associated tumor in the sigmoid colon. Colonoscopy revealed a large mucosal bulge in the sigmoid colon, approximately 32 cm inside the anus. The surface was rough with local erosion. The tumor was brittle on biopsy and bled easily. Computed tomography revealed thickening of the rectal wall with edema. Postoperative pathology indicated the likelihood of a perivascular epithelioid cell tumor. Histologically, the tumor comprised plump epithelioid cells with abundant clear to lightly eosinophilic cytoplasm and round nuclei arranged in an alveolar or trabecular pattern. The tumor cells were strongly positive for HMB-45, Melan-A, Cathepsin K, and TFE3 but negative for vimentin, smooth muscle actin, S100 protein, CD10, CK20, and desmin. The tumor cells had a low Ki-67 labeling index (approximately 2%). Fluorescence in situ hybridization revealed TFE3 fracture. Based on these histologic and immunohistochemical features, a diagnosis of melanotic Xp11-associated tumor of the sigmoid colon was made. CONCLUSION:In summary, we report the clinicopathological features of a primary tumor that is extremely rare in the sigmoid colon and review the clinicopathological characteristics of melanotic Xp11-associated tumors, compatible with the very rare tumor termed "melanotic Xp11 translocation renal cancer" in all aspects.


World J Clin Cases


Wang G,Li GG,Zhu SM,Cai BJ,Yu PJ,Zhang CW




Has Abstract


2019-03-06 00:00:00










  • CLAG-M chemotherapy followed by umbilical cord blood stem cell transplantation for primary refractory acute myeloid leukaemia in a child: A case report.

    abstract:BACKGROUND:The prognosis of paediatric primary refractory/relapsed acute myeloid leukaemia (R/R AML) remains poor. Intensive therapy is typically used as salvage treatment for those with R/R AML. No data are currently available about the use of the CLAG-M protocol as salvage therapy in paediatric patients with R/R AML....

    journal_title:World journal of clinical cases



    authors: Huang J,Yang XY,Rong LC,Xue Y,Zhu J,Fang YJ

    更新日期:2020-11-26 00:00:00

  • Reduced delay in diagnosis of odontogenic keratocysts with malignant transformation: A case report.

    abstract:BACKGROUND:In rare cases, odontogenic keratocysts (ODs) transform into squamous cell carcinoma. Intervals between the first attendance of a patient and the diagnosis of OD with malignant transformation vary from weeks to years. In this article, we report a case of malignancy derived from OD with a five-day delay in dia...

    journal_title:World journal of clinical cases



    authors: Luo XJ,Cheng ML,Huang CM,Zhao XP

    更新日期:2020-06-06 00:00:00

  • Association between resting energy expenditure, psychopathology and HPA-axis in eating disorders.

    abstract:AIM:To investigate the complex relationships between resting energy expenditure (REE), eating psychopathology, and Hypothalamus Pituitary Adrenal axis functioning in patients with eating disorders. METHODS:The study was designed as a cross-sectional survey, and it was planned by the Clinic for Eating Disorders of the ...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章


    authors: Castellini G,Castellani W,Lelli L,Sauro CL,Dini C,Lazzeretti L,Bencini L,Mannucci E,Ricca V

    更新日期:2014-07-16 00:00:00

  • Nutritional deficiencies in the pediatric age group in a multicultural developed country, Israel.

    abstract::Nutrient deficiencies are prevalent worldwide. Diseases and morbid conditions have been described to result from nutritional deficiencies. It is essential to address nutrient deficiencies as these may lead to chronic long-term health problems such as rickets, iron deficiency anemia, goiter, obesity, coronary heart dis...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章,评审


    authors: Haimi M,Lerner A

    更新日期:2014-05-16 00:00:00

  • Macrophage regulation of graft-vs-host disease.

    abstract::Hematopoietic stem cell transplantation has become a curative choice of many hematopoietic malignancy, but graft-vs-host disease (GVHD) has limited the survival quality and overall survival of hematopoietic stem cell transplantation. Understanding of the immune cells' reaction in pathophysiology of GVHD has improved, ...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章,评审


    authors: Hong YQ,Wan B,Li XF

    更新日期:2020-05-26 00:00:00

  • Cardiovascular impact of COVID-19 with a focus on children: A systematic review.

    abstract:BACKGROUND:Since the beginning of the pandemic, coronavirus disease-2019 (COVID-19) in children has shown milder cases and a better prognosis than adults. Although the respiratory tract is the primary target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), cardiovascular involvement is emerging as one ...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章


    authors: Rodriguez-Gonzalez M,Castellano-Martinez A,Cascales-Poyatos HM,Perez-Reviriego AA

    更新日期:2020-11-06 00:00:00

  • Hepatic amyloidosis leading to hepatic venular occlusive disease and Budd-Chiari syndrome: A case report.

    abstract:BACKGROUND:Systemic amyloidosis in which multiple systems can be involved has become a common clinical disease. When the liver is affected, symptoms such as abdominal distension, fatigue, edema, liver, and jaundice could appear. To date, hepatic amyloidosis combined with hepatic venular occlusive disease and Budd-Chiar...

    journal_title:World journal of clinical cases



    authors: Li TT,Wu YF,Liu FQ,He FL

    更新日期:2019-10-26 00:00:00

  • A large basal cell adenoma extending to the ipsilateral skull base and mastoid in the right parotid gland: A case report.

    abstract:BACKGROUND:Basal cell adenoma (BCA) is a rare benign tumour that has unique histological characteristics and primarily arises in the parotid glands. According to published reports, nearby tissue destruction by BCA seems impossible. CASE SUMMARY:We presented a case of a 54-year-old woman with a mass in the deep lobe of...

    journal_title:World journal of clinical cases



    authors: Du LY,Weng XH,Shen ZY,Cheng B

    更新日期:2019-06-06 00:00:00

  • Indolent lung opacity: Ten years follow-up of pulmonary inflammatory pseudo-tumor.

    abstract::Inflammatory pseudotumor (IPT) has always been considered a diagnostic challenge. Its rarity and resemblance to other more common pathological entities imposes that neither clinical nor radiological characteristics can lead to a definitive diagnosis. The surgical excision of the lesion is the ultimate approach for acc...

    journal_title:World journal of clinical cases



    authors: Degheili JA,Kanj NA,Koubaissi SA,Nasser MJ

    更新日期:2017-02-16 00:00:00

  • Accuracy of endoscopic ultrasound-guided needle aspiration specimens for molecular diagnosis of non-small-cell lung carcinoma.

    abstract:BACKGROUND:Endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA) and endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) are highly sensitive for diagnosing and staging lung cancer. In recent years, targeted therapy has shown great significance in the treatment of non-small cell lu...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章


    authors: Su W,Tian XD,Liu P,Zhou DJ,Cao FL

    更新日期:2020-11-06 00:00:00

  • Treatment of afferent loop syndrome using fluoroscopic-guided nasointestinal tube placement: Two case reports.

    abstract:BACKGROUND:Afferent loop syndrome (ALS) is a rare mechanical complication that occurs after reconstruction of the stomach or esophagus to the jejunum, such as Billroth II gastrojejunostomy, Roux-en-Y gastrojejunostomy, or Roux-en-Y esophagoje-junostomy. Traditionally, an operation is the first choice for benign causes....

    journal_title:World journal of clinical cases



    authors: Hu HT,Ma FH,Wu ZM,Qi XH,Zhong YX,Xie YB,Tian YT

    更新日期:2020-11-06 00:00:00

  • Inverse correlation between CD8+ inflammatory cells and E-cadherin expression in gallbladder cancer: Tissue microarray and imaging analysis.

    abstract:AIM:To investigated the association between the tumor cells' expression of E-cadherin and the numbers of several types of inflammatory cells infiltrating into the invasive portion of gallbladder cancer (GBC). METHODS:We analyzed 50 GBC cases for which a sufficient amount of tumor tissues for tissue microarray (TMA) ha...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章


    authors: Kai K,Masuda M,Aishima S

    更新日期:2017-01-16 00:00:00

  • Peritoneal cavernous hemangiomatosis: A case report.

    abstract:BACKGROUND:Cavernous hemangiomatosis in the liver and spleen has been reported, but it occurs less commonly in the peritoneum. Here we report a case of peritoneal cavernous hemangiomatosis and share some valuable information about this disease. CASE SUMMARY:A 57-year-old Chinese man had a huge abdominal mass with abdo...

    journal_title:World journal of clinical cases



    authors: Fu LY,Chen HY,Diao XL,Wang ZJ

    更新日期:2019-02-26 00:00:00

  • Therapeutic experience of an 89-year-old high-risk patient with incarcerated cholecystolithiasis: A case report and literature review.

    abstract:BACKGROUND:The global pandemic of coronavirus disease 2019 pneumonia poses a particular challenge to the emergency surgical treatment of elderly patients with high-risk acute abdominal diseases. Elderly patients are a high-risk group for surgical treatment. If the incarceration of gallstones cannot be relieved, emergen...

    journal_title:World journal of clinical cases



    authors: Zhang ZM,Zhang C,Liu Z,Liu LM,Zhu MW,Zhao Y,Wan BJ,Deng H,Yang HY,Liao JH,Zhu HY,Wen X,Liu LL,Wang M,Ma XT,Zhang MM,Liu JJ,Liu TT,Huang NN,Yuan PY,Gao YJ,Zhao J,Guo XA,Liao F,Li FY,Wang XT,Yuan RJ,Wu

    更新日期:2020-10-26 00:00:00

  • Association between liver targeted antiviral therapy in colorectal cancer and survival benefits: An appraisal.

    abstract::In colorectal cancer (CRC), liver metastasis remains a major contributor to the cause of cancer-related death. Putative biomarkers, therapeutic efficacy, and drug insensitivity still pose clinical challenges for metastatic CRC patients. Interestingly, previous studies indicated that tumor cells in CRC did not metastas...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章,评审


    authors: Wang Q,Yu CR

    更新日期:2020-06-06 00:00:00

  • Pre- and intraoperative predictors of acute kidney injury after liver transplantation.

    abstract:BACKGROUND:Acute kidney injury (AKI) after liver transplantation (LT) is a frequent and multifactorial event related to increased morbidity and mortality. Risk factors for AKI after LT still need to be clarified. AIM:To identify the predictors of acute kidney injury after liver transplantation. METHODS:The frequency ...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章


    authors: Mrzljak A,Franusic L,Pavicic-Saric J,Kelava T,Jurekovic Z,Kocman B,Mikulic D,Budimir-Bekan I,Knotek M

    更新日期:2020-09-26 00:00:00

  • Role of quorum sensing in bacterial infections.

    abstract::Quorum sensing (QS) is cell communication that is widely used by bacterial pathogens to coordinate the expression of several collective traits, including the production of multiple virulence factors, biofilm formation, and swarming motility once a population threshold is reached. Several lines of evidence indicate tha...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章,评审


    authors: Castillo-Juárez I,Maeda T,Mandujano-Tinoco EA,Tomás M,Pérez-Eretza B,García-Contreras SJ,Wood TK,García-Contreras R

    更新日期:2015-07-16 00:00:00

  • Expander implantation for correction of high-riding nipple with enlarged nipple-areola complex using revision mastopexy: A case report.

    abstract:BACKGROUND:High-riding nipple is one of the common complications after mastopexty and breast reconstruction. However, to date, a limited number of techniques have concentrated on how to lower the high-riding nipple with enlarged areola. CASE SUMMARY:This is a case report describing a combination of surgical techniques...

    journal_title:World journal of clinical cases



    authors: Qin F,Yu NZ,Yang E,Zeng A,Hao Y,Zhu L,Wang XJ

    更新日期:2020-05-06 00:00:00

  • Modified procedure for prolapse and hemorrhoids: Lower recurrence, higher satisfaction.

    abstract:BACKGROUND:Hemorrhoidal prolapse is a common benign disease with a high incidence. The treatment procedure for prolapse and hemorrhoids (PPH) remains an operative method used for internal hemorrhoid prolapse. Although it is related to less pos-operative pain, faster recovery and shorter hospital stays, the postoperativ...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章


    authors: Chen YY,Cheng YF,Wang QP,Ye B,Huang CJ,Zhou CJ,Cai M,Ye YK,Liu CB

    更新日期:2021-01-06 00:00:00

  • Severe isolated sciatic neuropathy due to a modified lotus position.

    abstract::A 51-year-old man presented to our hospital with progressive pain and weakness in his right leg. Neurological examination revealed atrophy of all muscles of the right leg, unilateral foot drop and paralysis of the anterior tibial and gastrocnemicus muscles. Electromyography confirmed a severe isolated sciatic neuropat...

    journal_title:World journal of clinical cases



    authors: Bosma JW,Wijntjes J,Hilgevoord TA,Veenstra J

    更新日期:2014-02-16 00:00:00

  • New device to implement the adenoma detection rate.

    abstract::It is well-known that colonoscopy is considered the gold standard for colon cancer prevention. Although performed by experienced endoscopists, the matter remains of polyps missed during this examination. The reasons may include the size, shape and location of the lesions. Many colorectal cancer screening programs have...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章,评审


    authors: Zippi M,Hong W,Crispino P,Traversa G

    更新日期:2017-07-16 00:00:00

  • Teriparatide as nonoperative treatment for femoral shaft atrophic nonunion: A case report.

    abstract:BACKGROUND:Femoral shaft fractures are a common type of fracture among adults and have high union rates. However, clinical decisions are difficult to make because of the different types of nonunions. Atrophic nonunion usually requires revision surgery combined with bone grafting. Furthermore, no study of teriparatide a...

    journal_title:World journal of clinical cases



    authors: Tsai MH,Hu CC

    更新日期:2019-09-26 00:00:00

  • Clinical effects of apatinib mesylate for treatment of multiple brain micrometastases: Two case reports.

    abstract:BACKGROUND:Apatinib is a small-molecule multitargeted tyrosine kinase inhibitor. Apatinib has demonstrated encouraging antitumor activities. This study aimed to observe the efficacy and safety of apatinib for the treatment of multiple brain micrometastases. CASE SUMMARY:We report two patients with multiple brain micro...

    journal_title:World journal of clinical cases



    authors: Guo JH,Wang YY,Zhang JW,Liu PM,Hao YJ,Duan HR

    更新日期:2020-04-06 00:00:00

  • Oxygen insufflation via working channel in a fiberscope is a useful method: A case report and review of literature.

    abstract:BACKGROUND:Fiberoptic bronchoscopic intubation is the gold standard for endotracheal intubation in difficult or compromised airway situations. However, oxygen insufflation through the working channel of a fiberscope is a controversial method because of the possibility of gastric distention and rupture during an awake f...

    journal_title:World journal of clinical cases



    authors: Lee D,Baik J,Yun G,Kim E

    更新日期:2018-12-26 00:00:00

  • Mediastinal small cell carcinoma with liver and bone marrow metastasis, mimicking lymphoma.

    abstract::Primary mediastinal neuroendocrine tumors are a rare malignancy that accounts for < 10% of all mediastinal tumors. The case presented here involves a 52-year-old man who had been suffering for 3 mo from chronic cough, anorexia and substantial weight loss, as well as 2 wk of jaundice prior to his admission. A computed ...

    journal_title:World journal of clinical cases



    authors: Nawarawong N,Pongpruttipan T,Aswakul P,Prachayakul V

    更新日期:2015-10-16 00:00:00

  • Trans-sacral screw fixation in the treatment of high dyplastic developmental spondylolisthesis.

    abstract::We describe the case of a 67-year-old woman with L5-S1 ontogenetic spondylolisthesis treated with pedicle fixation associated with interbody arthrodesis performed with S1-L5 trans-sacral screwing according to the technique of Bartolozzi. The procedure was followed by a wide decompressive laminectomy. The patient had a...

    journal_title:World journal of clinical cases



    authors: Landi A,Marotta N,Mancarella C,Tarantino R,Delfini R

    更新日期:2013-06-16 00:00:00

  • Risk factors, clinical features, and short-term prognosis of spontaneous fungal peritonitis in cirrhosis: A matched case-control study.

    abstract:BACKGROUND:Spontaneous peritonitis is one of the most common infectious complications in cirrhotic patients with ascites. Spontaneous fungal peritonitis (SFP) is a type of spontaneous peritonitis that is a less recognized but devastating complication in end-stage cirrhosis. Although high mortality was previously noted,...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章


    authors: Huang CH,Pang LT,Xu LC,Ge TT,Xu QM,Chen Z

    更新日期:2019-09-06 00:00:00

  • Can cyclin-dependent kinase 4/6 inhibitors convert inoperable breast cancer relapse to operability? A case report.

    abstract:BACKGROUND:Pathological complete response (pCR) is rare in hormone receptor-positive (HR+) HER2-negative breast cancer (BC) treated with either endocrine therapy (ET) or chemotherapy. Radical resection of locoregional relapse, although potentially curative in some cases, is challenging when the tumor invades critical s...

    journal_title:World journal of clinical cases



    authors: Palleschi M,Maltoni R,Barzotti E,Melegari E,Curcio A,Cecconetto L,Sarti S,Manunta S,Rocca A

    更新日期:2020-02-06 00:00:00

  • Robot-assisted retroperitoneal laparoscopic excision of perirenal vascular tumor: A case report.

    abstract:BACKGROUND:A vascular tumor is a benign tumor with unique clinical and pathological features. Perirenal vascular tumor is extremely rare and has not yet been reported. Clinically, it manifests as soreness and swelling. Color ultrasound and renal angiography illustrated the perirenal mass, which was closely connected wi...

    journal_title:World journal of clinical cases



    authors: Zhang C,Fu B,Xu S,Zhou XC,Cheng XF,Fu WQ,Wang GX

    更新日期:2020-05-26 00:00:00

  • Preliminary analysis of the effect of vagus nerve stimulation in the treatment of children with intractable epilepsy.

    abstract:BACKGROUND:Implant vagus nerve stimulation is an adjunctive treatment for intractable epilepsy when patients are not suitable for resective surgery. AIM:To identify the safety and efficacy of vagus nerve stimulation in children with intractable epilepsy and analyze the effects on different epilepsy syndromes. METHODS...

    journal_title:World journal of clinical cases

    pub_type: 杂志文章


    authors: Fang T,Xie ZH,Liu TH,Deng J,Chen S,Chen F,Zheng LL

    更新日期:2020-12-06 00:00:00