Abstract:
BACKGROUND:Melanotic Xp11-associated tumors are rare mesenchymal-derived tumors. So far, most primary melanotic Xp11-associated tumors have been reported in the kidney, and reports of this tumor in the gastrointestinal tract are rare. CASE SUMMARY:Here we describe the case of a 25-year-old woman who presented with a melanotic Xp11-associated tumor in the sigmoid colon. Colonoscopy revealed a large mucosal bulge in the sigmoid colon, approximately 32 cm inside the anus. The surface was rough with local erosion. The tumor was brittle on biopsy and bled easily. Computed tomography revealed thickening of the rectal wall with edema. Postoperative pathology indicated the likelihood of a perivascular epithelioid cell tumor. Histologically, the tumor comprised plump epithelioid cells with abundant clear to lightly eosinophilic cytoplasm and round nuclei arranged in an alveolar or trabecular pattern. The tumor cells were strongly positive for HMB-45, Melan-A, Cathepsin K, and TFE3 but negative for vimentin, smooth muscle actin, S100 protein, CD10, CK20, and desmin. The tumor cells had a low Ki-67 labeling index (approximately 2%). Fluorescence in situ hybridization revealed TFE3 fracture. Based on these histologic and immunohistochemical features, a diagnosis of melanotic Xp11-associated tumor of the sigmoid colon was made. CONCLUSION:In summary, we report the clinicopathological features of a primary tumor that is extremely rare in the sigmoid colon and review the clinicopathological characteristics of melanotic Xp11-associated tumors, compatible with the very rare tumor termed "melanotic Xp11 translocation renal cancer" in all aspects.
journal_name
World J Clin Casesjournal_title
World journal of clinical casesauthors
Wang G,Li GG,Zhu SM,Cai BJ,Yu PJ,Zhang CWdoi
10.12998/wjcc.v7.i5.684subject
Has Abstractpub_date
2019-03-06 00:00:00pages
684-690issue
5issn
2307-8960journal_volume
7pub_type
abstract::Acute pancreatitis is rarely associated with drugs. Acetaminophen overdose is a well-known cause of hepatic toxicity, but drug-induced pancreatitis is rarely reported, especially after mild overdose. A 32-year-old woman presented with nausea and vomiting for 12 h, but no abdominal pain following an overdose of eight T...
journal_title:World journal of clinical cases
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doi:10.12998/wjcc.v6.i9.291
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abstract:BACKGROUND:High-riding nipple is one of the common complications after mastopexty and breast reconstruction. However, to date, a limited number of techniques have concentrated on how to lower the high-riding nipple with enlarged areola. CASE SUMMARY:This is a case report describing a combination of surgical techniques...
journal_title:World journal of clinical cases
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abstract:BACKGROUND:An isthmocele is a scar defect in the uterine wall due to a cesarean section. Its prevalence is unknown, but it has been associated with secondary infertility. Here, we present a case where the patient suffered from an isthmocele that was associated with persistent hydrometra, which developed during in vitro...
journal_title:World journal of clinical cases
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doi:10.12998/wjcc.v7.i6.753
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journal_title:World journal of clinical cases
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doi:10.12998/wjcc.v7.i16.2346
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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abstract:BACKGROUND:Invasive fungal rhinosinusitis (IFR) caused by Cunninghamella is very rare but has an extremely high fatality rate. There have been only seven cases of IFR caused by Cunninghamella reported in English and, of these, only three patients survived. In this article, we present another case of IFR caused by Cunni...
journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v7.i2.228
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journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
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更新日期:2020-06-26 00:00:00
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journal_title:World journal of clinical cases
pub_type: 杂志文章
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更新日期:2014-05-16 00:00:00
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journal_title:World journal of clinical cases
pub_type:
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更新日期:2020-10-06 00:00:00
abstract:AIM:To study the antibiotic susceptibility patterns of gram-negative healthcare associated bacterial infections at two tertiary hospitals in the Sanandaj city, Kurdistan Province, Iran. METHODS:From January 2012 to December 2012, all positive cultures from potentially sterile body fluids were gathered. They sent to pr...
journal_title:World journal of clinical cases
pub_type: 杂志文章
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journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
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journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
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journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
pub_type:
doi:10.12998/wjcc.v8.i1.217
更新日期:2020-01-06 00:00:00
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journal_title:World journal of clinical cases
pub_type: 杂志文章,评审
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
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journal_title:World journal of clinical cases
pub_type:
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更新日期:2021-01-16 00:00:00
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journal_title:World journal of clinical cases
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更新日期:2014-08-16 00:00:00
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journal_title:World journal of clinical cases
pub_type: 杂志文章
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journal_title:World journal of clinical cases
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