Overexpression of the Ubiquilin-4 (UBQLN4) is Associated with Cell Cycle Arrest and Apoptosis in Human Normal Gastric Epithelial Cell Lines GES-1 Cells by Activation of the ERK Signaling Pathway.

abstract：:Endogenous morphine is present in the mammalian brain as determined by gas chromatography/mass spectrometry. The criteria essential for satisfying the definition of morphine as a neurotransmitter are examined. The detection of endogenous morphine-like compounds inside brain neurons by immunocytochemistry and the Ca(+)...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Guarna M,Ghelardini C,Galeotti N,Stefano GB,Bianchi E

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:The 47,XXX karyotype is a rare sex chromosome anomaly. This karyotype is usually not associated with a characteristic physical phenotype. CASE REPORT:In presented case a 47 triple X women with pituitary tumor and premature ovarian failure is identified. Diagnosis of a 47,XXX individual remains difficult bec...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Witek A,Skałba P,Zieba M

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Cigarette smoke (CS) is associated with oxidative stress in several organs because it contains high concentrations of free radicals and reactive oxygen species. Experimental models, using different strains, provide important insights into the genetic basis of diseases. This study sought to identify, in diffe...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Rueff-Barroso CR,Trajano ET,Alves JN,Paiva RO,Lanzetti M,Pires KM,Bezerra FS,Pinho RA,Valenca SS,Porto LC

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The role of physical activity in a health-seeking life style is increasingly and frequently about the improvement of one's silhouette. This constitutes the problem that we are trying to resolve in this article--are physical activities a part of actions aimed at the reduction of weight in people trying to los...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lipowski M,Buliński L,Krawczyński M

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is the most common interstitial lung disease and is usually associated with a poor prognosis. IPF patients have a significant impairment in health-related quality of life (HRQL), both in terms of physical and psychological functioning. A substantial number of dyspnea scale...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Baddini Martinez JA,Martinez TY,Lovetro Galhardo FP,de Castro Pereira CA

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:We compared cardiac electrophysiological indicators and regional expression levels of cardiac hyperpolarization-activated cyclic nucleotide-gated (HCN) channels between adult and aged dogs to identify possible mechanisms of age-related atrial fibrillation. MATERIAL/METHODS:Corrected sinus node recovery time...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li YD,Hong YF,Zhang Y,Zhou XH,Ji YT,Li HL,Hu GJ,Li JX,Sun L,Zhang JH,Xin Q,Yusufuaji Y,Xiong J,Tang BP

更新日期：2014-11-14 00:00:00

abstract：BACKGROUND:The eradication of Helicobacter pylori (HP) is dependent on several bacteriologic and geographic variables. Multiple-drug regimens have been tried in order to eradicate HPi; however, the optimal drug has not yet been found. MATERIAL/METHODS:In this single-blind, randomized clinical trial, 245 dyspeptic pati...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Amini M,Khedmat H,Yari F

更新日期：2005-04-01 00:00:00

abstract：:Osterix (Osx) is an osteoblast-specific transcription factor that is essential for bone formation. MicroRNAs (miRNAs) are ~22-nucleotide-long noncoding RNAs that play important regulatory roles in animals and plants by targeting mRNAs for cleavage or translational repression. They can also control osteoblast-mediated ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang C,Liao H,Cao Z

更新日期：2016-08-20 00:00:00

abstract：BACKGROUND:Human saliva, a complex secretion that contains a mixture of inorganic and organic molecules, plays an essential role in the maintenance of oral health. Mucins are the major macromolecular component of the secretion and are considered the first line of defense for epithelial tissues. The aim of this study wa...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Gabryel-Porowska H,Gornowicz A,Bielawska A,Wójcicka A,Maciorkowska E,Grabowska SZ,Bielawski K

更新日期：2014-01-18 00:00:00

abstract：BACKGROUND:The possibility of functional tethered cord syndrome (TCS) should be considered when adolescent patients present with unexplained lumbar, buttock, and leg symptoms. Symptoms progress if untreated. Success depends on early diagnosis, the complete untethering of the spinal cord, and rehabilitation. A rare case...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Kabayel DD,Ozdemir F,Unlu E,Bilgili N,Murat S

更新日期：2007-12-01 00:00:00

abstract：:BACKGROUND The correlation between serum concentration of neuron specific enolase (NSE), S100B, and the prognosis of patients with acute spinal cord injury (ASCI) remains controversial. MATERIAL AND METHODS Sixty patients with confirmed diagnosis of ASCI were recruited for this study from February 2015 to January 2017...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Du W,Li H,Sun J,Xia Y,Zhu R,Zhang X,Tian R

更新日期：2018-06-30 00:00:00

abstract：MATERIAL AND METHODS:In 12 Wistar rats the gross and microscopic structure of haemolymph splenic nodes was assessed after splenectomy and the obtained results were compared with those in the control group. RESULTS:It was found that splenectomy leads to generalised morphological changes of the mentioned nodes, includin...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Slusarczyk K,Marniok B,Rudnicki P

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Bax activation and intracellular redistribution as well as its prognostic significance during steroid-induced apoptosis of leukemic cells in childhood acute lymphoblastic leukemia (ALL) remain a matter of controversy. The purpose of this study was to assess time-resolved changes in Bax activation and its int...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Urasiński T,Urasińska E,Grabarek J,Fydryk J,Domagała W

更新日期：2009-06-01 00:00:00

abstract：:BACKGROUND The hepatotoxicity of Tripterygium wilfordii Hook. f. (TWHF) limits its clinic utilization. Qingluo Tongbi formula (QTF) was formulated based on a basic Chinese medicine theory. Previous studies have confirmed the safety and efficacy of QTF in treating rheumatoid arthritis. Therefore, we considered that TWH...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li M,Wang J,Fu L,Lu Y,Xu J,Zhou L,Zhu H,Fang L,Feng Z,Xie T,Zhou X

更新日期：2020-02-15 00:00:00

abstract：BACKGROUND:This study was designed to evaluate maternal levels of leptin and interferon-gamma (IFN-gamma) in pregnancy complicated with hypertension and to assess the role of cytokines in predicting the risk of cesarean section. MATERIAL/METHODS:This was a cohort study with a prospective follow-up. After proportional ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Rytlewski K,Huras H,Kuśmierska-Urban K,Gałaś A,Reroń A

更新日期：2012-08-01 00:00:00

abstract：:In this paper we highlight the role and contributions of Latin American researchers in the study of systemic lupus erythematosus (SLE). The first case of SLE in the world was probably from a mummy from the Huary culture in Peru from about 890 AD, which was extensively studied by macroscopic examination and with light ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Gamarra AI,Matteson EL,Rodriquez AI,Rodriguez MI,Restrepo Suarez JF

更新日期：2004-07-01 00:00:00

abstract：:BACKGROUND Following a thoracolumbar burst fracture (TCBF), anterior screw-rods apply pressure upon the graft site. However, there is limited evidence comparing single screw-rod anterior instrumentation (SSRAI) to double screw-rod anterior instrumentation (DSRAI) for TCBFs. Our objective was to compare SSRAI versus DS...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yu Y,Wang J,Shao G,Wang Q,Li B

更新日期：2016-05-19 00:00:00

abstract：BACKGROUND:Cnidium lactone is a natural coumarin compound that can inhibit a variety of cancer cell proliferation and induce cancer cell apoptosis. This experiment investigated the effect of cnidium lactone on molecular marker expression in prostate cancer nude mice to study its effect in inducing apoptosis. MATERIAL ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Bi D,Yang M,Zhao X,Huang S

更新日期：2015-08-18 00:00:00

abstract：:This article discusses the role of transcription factors in vascular endothelial growth factor (VEGF) gene expression. Angiogenesis is a complex and multilevel process of new capillary formation on the basis of already existing blood vessels. Physiologically, it is a very strictly regulated process, which results in a...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jośko J,Mazurek M

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:The goal of the presented studies as a retrospective reliability assessment of classical banding cytogenetic studies and of prognosing epicrises in a group of 14 cases, affected with additional marker chromosomes. MATERIAL AND METHODS:Having collected the study material from peripheral blood, by means of tr...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Kałuzewski B,Helszer Z,Constantinou M,Burkholder SW,Coutinho WG,Skorski M,Corridori L,Anderson CE,Sherwood M,Debiec-Rychter M,Jackson LG

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the effect of diabetic autonomic neuropathy (AN) on the incretin effect in patients with type 2 diabetes mellitus (DM2). MATERIAL/METHODS:Forty patients with DM2 (20 with and 20 without AN) and 10 healthy controls were studied. The subjects underwent an oral glucose to...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Kazakos KA,Sarafidis PA,Yovos JG

更新日期：2008-04-01 00:00:00

abstract：:BACKGROUND The aim of this study was to explore the emotional resilience of middle school students learning at home in February and March 2020 during the COVID-19 pandemic, and the impact of this resilience on students' learning management skills. The results could provide a basis for psychological health education of...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang Q,Zhou L,Xia J

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Interferon-gamma release assays have not been validated in active TB among pregnant women. Therefore, the objective of this retrospective study was to estimate the diagnostic value of T-SPOT.TB in active TB among pregnant women. MATERIAL/METHODS:Between May 2012 and May 2015, 26 consecutive pregnant women w...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen Q,Guo X,Wang X,Wang M

更新日期：2016-01-06 00:00:00

abstract：BACKGROUND:Currently available treatment options for decompensated hepatitis B-induced liver cirrhosis are limited and largely ineffective. Recently, stem cell transplantation has emerged as a promising treatment for cirrhosis. The aim of this study was to determine whether autologous peripheral blood stem cell transpl...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Cai T,Deng Q,Zhang S,Hu A,Gong Q,Zhang X

更新日期：2015-05-13 00:00:00

abstract：BACKGROUND:Small interfering RNA (siRNA) gene therapy is a new molecular approach in the search for an efficient therapy for Alzheimer disease (AD), based on the principle of RNA interference. Reducing BACE activity can have great therapeutic potential for the treatment of AD. In this study, receptor-mediated delivery ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jabłkowski M,Szemraj M,Oszajca K,Janiszewska G,Bartkowiak J,Szemraj J

更新日期：2014-12-10 00:00:00

abstract：BACKGROUND:Oral breathing causes many changes in the facial anatomical structures in adult patients. In this study we aimed to determine the effects of long-term oral breathing (>5 years) on the maxillary sinus volumes among adult male patients. MATERIAL/METHODS:We accessed medical records of 586 patients who had unde...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Agacayak KS,Gulsun B,Koparal M,Atalay Y,Aksoy O,Adiguzel O

更新日期：2015-01-02 00:00:00

abstract：BACKGROUND:The aim of the study was to assess the prognostic value of HCV RNA detection in hepatic tissue for the response to treatment with interferon alfa (IFN) and ribavirin (RIB) in patients with chronic hepatitis C. PATIENTS AND METHODS:A group of 55 patients infected with HCV was examined before the commencement...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lakomy EA,Bielawski KP,Sikorska K,Stalke P,Michalska Z,Witczak-Malinowska K

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:This study was designed to clarify the significance of washout rate (WR) determined from 99mTc-sestamibi myocardial scintigraphic images and the levels of cardiac enzymes in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). MATERIAL/METHODS:A total of 56 consecu...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Akashi YJ,Ashikaga K,Takano M,Izumo M,Ishibashi Y,Kida K,Yoneyama K,Suzuki K,Miyake F,Banach M

更新日期：2011-02-25 00:00:00

abstract：:BACKGROUND The downregulation of tropomyosin 1 (TPM1) has been observed in various tumors, but few studies have focused on the clinical significance of TPM1 in intrahepatic cholangiocarcinoma (ICC). In the present study, we investigated the prognostic significance of TPM1 in ICC. MATERIAL AND METHODS A total of 124 pa...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen Y,Hong Z,Lu S,Zhang N,Rong G,Chang X,Liu Z,Bai W,Dong Z,Gao X,Zeng Z,Lu Y

更新日期：2018-11-03 00:00:00

abstract：:BACKGROUND Albuminuria has been associated with cardiovascular events, but whether such an association can be explained by endothelial dysfunction is not fully understood. In this study, we examined the relationship between the urine albumin-to-creatinine ratio (UACR) and biomarkers of endothelial function in patients...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huang MJ,Wei RB,Zhao J,Su TY,Li QP,Yang X,Chen XM

更新日期：2017-09-15 00:00:00