Abstract:
BACKGROUND:The double burden of tuberculosis (TB) and diabetes mellitus (DM) is hitting certain Asian countries harder than other areas. In a global estimate, 15% of all TB cases could be attributable to DM, with 40% of those cases coming from India and China. Many other countries of South, East, and South-East Asia are of particular concern given their TB burdens, large projected increases in DM prevalence, and population size. OBJECTIVE:In this narrative review, we aimed to: (i) give an overall insight into the evidence on TB-DM epidemiology from high double burden Asian countries, (ii) present the evidence on bi-directional screening implementation in this region, (iii) discuss possible factors related to higher TB susceptibility of Asian diabetic patients, and (iv) identify TB-DM comorbidity treatment challenges. METHODS:The PubMed and Google Scholar databases were searched for all studies addressing DM/TB epidemiology, bi-directional screening and management in South, East and South-East Asia. RESULTS:We identified the DM prevalences among TB patients as ranging from approximately 5% to more than 50%, whereas TB prevalences among diabetic patients were 1.8-9.5 times higher than in the general population in developing Asian countries. Evidence from studies designed to address diagnosis and treatment of the dual disease in these critical regions is scarce as well as the evidence related to possible DM patients' genetic and acquired predisposition for TB. CONCLUSION:More prospective studies specifically designed to address adequate screening techniques, identify patients at risk, and define an adequate treatment of dual disease in this region are needed without delay.
journal_name
Glob Health Actionjournal_title
Global health actionauthors
Zheng C,Hu M,Gao Fdoi
10.1080/16549716.2016.1264702subject
Has Abstractpub_date
2017-01-01 00:00:00pages
1-11issue
1eissn
1654-9716issn
1654-9880journal_volume
10pub_type
杂志文章,评审abstract:BACKGROUND:Previous research has shown that men who have sex with men (MSM) avoid formal healthcare services because of the fear of discrimination as homosexuality is illegal and stigmatized in Tanzania. Instead, self-treatment by medications obtained directly from pharmacies or drugstores may be common when MSM experi...
journal_title:Global health action
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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journal_title:Global health action
pub_type: 杂志文章
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journal_title:Global health action
pub_type: 杂志文章,评审
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journal_title:Global health action
pub_type: 杂志文章
doi:10.3402/gha.v4i0.5435
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journal_title:Global health action
pub_type: 杂志文章
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journal_title:Global health action
pub_type: 杂志文章
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journal_title:Global health action
pub_type: 杂志文章
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journal_title:Global health action
pub_type: 杂志文章
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journal_title:Global health action
pub_type: 杂志文章
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journal_title:Global health action
pub_type: 杂志文章
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更新日期:2016-02-09 00:00:00
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journal_title:Global health action
pub_type: 杂志文章,评审
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journal_title:Global health action
pub_type: 杂志文章
doi:10.1080/16549716.2017.1356641
更新日期:2017-01-01 00:00:00
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journal_title:Global health action
pub_type: 杂志文章
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journal_title:Global health action
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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journal_title:Global health action
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doi:10.3402/gha.v7.25317
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