Percutaneous autologous bone marrow injections for delayed or non-union of bones.

Abstract:

PURPOSE:To evaluate 12 patients with delayed or nonunion of bones treated with bone marrow injections. METHODS:6 men and 6 women aged 15 to 70 (mean, 45) years underwent bone marrow injections for delayed union (n=2) or atrophic non-union (n=10) of the ulna (n=6), femur (n=3), humerus (n=2), or metacarpal (n=1). Bone marrow was aspirated from the anterior iliac crest and injected to the delayed and non-union sites. Two injections were given for children and adolescents, and 3 for adults. The interval between the injections was 6 to 8 weeks. The amount of bone marrow injected was 30 to 40 ml for long bones and 20 ml for metacarpals. RESULTS:Ten of the 12 delayed or non-union of bones healed after bone marrow injections. The mean time for callus formation was 5.8 (range, 3-10) weeks, for clinical union was 7 (range, 4-12) weeks, and for radiological union was 16 (range, 10-24) weeks. CONCLUSION:Multiple injections of low-volume bone marrow can be used for treatment of delayed or non-union of bones.

authors

Singh AK,Shetty S,Saraswathy JJ,Sinha A

doi

10.1177/230949901302100116

subject

Has Abstract

pub_date

2013-04-01 00:00:00

pages

60-4

issue

1

eissn

1022-5536

issn

2309-4990

journal_volume

21

pub_type

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