Abstract:
:Spondylolysis is a major cause of back pain in children and adolescents. The prevalence of spondylolysis depends on the sex, race, and congenital abnormality. These biases suggest hereditary predisposition as an etiology of spondylolysis. However, no conclusive evidence still exists regarding the inheritance for spondylolysis. Herein, we report rare cases with familial occurrence of lumbar spondylolysis. In two generations of a Japanese family, three brothers including identical twins complained of back pain related to sports activities. Clinical, radiographic, and computed tomographic examinations identified spondylolysis at L4 and L5 in all these boys. The father experienced long-term back pain and had spondylolisthesis at L4-L5 and healed spondylolysis at L5. The daughter and mother did not show any lumbar spondylolysis. The frequent development of spondylolysis at L4, a rarely affected segment, in four of six family members (66.7%) support that lumbar spondylolysis has an underlying genetic etiology, primarily autosomal dominant inheritance.
journal_name
J Orthop Surg (Hong Kong)journal_title
Journal of orthopaedic surgery (Hong Kong)authors
Yurube T,Kakutani K,Okamoto K,Manabe M,Maeno K,Yoshikawa M,Sha N,Kuroda R,Nishida Kdoi
10.1177/2309499017713917subject
Has Abstractpub_date
2017-05-01 00:00:00pages
2309499017713917issue
2eissn
1022-5536issn
2309-4990journal_volume
25pub_type
杂志文章abstract:OBJECTIVE:This study evaluated the efficacy of surgery for femoral neck fractures in children after a 24-h delay and the factors affecting the risk of complications. METHODS:The study included 16 children who underwent surgery after the first 24 h for femoral neck fractures. According to Delbet's classification, there...
journal_title:Journal of orthopaedic surgery (Hong Kong)
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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更新日期:2014-08-01 00:00:00
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journal_title:Journal of orthopaedic surgery (Hong Kong)
pub_type: 杂志文章,评审
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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pub_type: 杂志文章,随机对照试验
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更新日期:2018-05-01 00:00:00
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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更新日期:2001-06-01 00:00:00
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journal_title:Journal of orthopaedic surgery (Hong Kong)
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更新日期:2020-01-01 00:00:00
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更新日期:2019-01-01 00:00:00