N-acetylaspartate, choline, myoinositol, glutamine and glutamate (glx) concentration changes in proton MR spectroscopy (1H MRS) in patients with mild cognitive impairment (MCI).

abstract：:BACKGROUND More and more recent studies have clearly shown that long non-coding RNA (lncRNA) should be considered as a fundamental part of the ceRNA network, mainly because lncRNA can act as miRNA sponges to regulate the protein-coding gene expression. Nevertheless, it is still not clear how lncRNA-mediated ceRNAs fun...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen W,Chen X,Wang Y,Liu T,Liang Y,Xiao Y,Chen L

更新日期：2019-04-09 00:00:00

abstract：:BACKGROUND YM155, which inhibits the anti-apoptotic protein survivin, is known to exert anti-tumor effects in various cancers. However, there were few reports describing the inhibitory effect of YM155 on human oral squamous cell carcinoma (OSCC) cells that highly express survivin. In this study, we investigated the an...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yan X,Su H

更新日期：2017-04-24 00:00:00

abstract：BACKGROUND:An increase in the prevalence of thyroid disease has been found with increasing iodine intake, since universal salt iodization (USI) was instituted throughout China in 1996. The aim of this study was to analyze the incidence of thyroid carcinoma (TC) before and after USI in Shenyang, a city of northeastern C...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Dong W,Zhang H,Zhang P,Li X,He L,Wang Z,Liu Y

更新日期：2013-01-14 00:00:00

abstract：BACKGROUND:The Total Cavopulmonary Connection (TCPC), used for repair of patients with single ventricle physiology, creates a passive system of blood flow into the pulmonary circulation where enhanced energy efficiency may lead to improved long term patient outcomes. Previous numerical and in vitro studies using steady...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： DeGroff CG,Shandas R

更新日期：2002-03-01 00:00:00

abstract：:Long non-coding RNA (lncRNA) is a kind of non-coding RNA with transcripts more than 200 bp in length. LncRNA can interact with the miRNA as a competing endogenous RNA (ceRNA) to regulate the expression of target genes, which play a significant role in the initiation and progression of tumors. In this study, we explore...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li F,Huang C,Li Q,Wu X

更新日期：2018-01-03 00:00:00

abstract：:Endogenous morphine is present in the mammalian brain as determined by gas chromatography/mass spectrometry. The criteria essential for satisfying the definition of morphine as a neurotransmitter are examined. The detection of endogenous morphine-like compounds inside brain neurons by immunocytochemistry and the Ca(+)...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Guarna M,Ghelardini C,Galeotti N,Stefano GB,Bianchi E

更新日期：2005-06-01 00:00:00

abstract：:BACKGROUND The purpose of this study was to evaluate the utility of multi-detector computed tomography (MDCT) angiography and transthoracic echocardiography (TTE) in the diagnosis of congenital coarctation of the aorta (CoA) and accompanying malformations in infants. MATERIAL AND METHODS From January 2012 and December...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Huang F,Chen Q,Huang WH,Wu H,Li WC,Lai QQ

更新日期：2017-05-16 00:00:00

abstract：:BACKGROUND To investigate the correlation between the relative computed tomography (CT) enhancement value and the microvascular architecture in different pathologic subtypes of renal cell carcinoma (RCC). MATERIAL AND METHODS This retrospective study included 55 patients with pathologically confirmed RCC. Immunohistoc...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ouyang AM,Wei ZL,Su XY,Li K,Zhao D,Yu DX,Ma XX

更新日期：2017-07-31 00:00:00

abstract：:BACKGROUND In an atherosclerotic artery wall, monocyte-derived macrophages are the principal mediators that respond to pathogens and inflammation. The present study aimed to investigate potential genetic changes in gene expression between normal tissue-resident macrophages and atherosclerotic macrophages in the human ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang W,Zhang K,Zhang H,Li M,Zhao Y,Wang B,Xin W,Yang W,Zhang J,Yue S,Yang X

更新日期：2019-12-25 00:00:00

abstract：:BACKGROUND The aim of this study was to evaluate the elution of BisGMA, UDMA, TEGDMA, and HEMA monomers from flowable bulk fill composite resins with different resin matrix compositions, polymerized in 4-mm-thick layers, into 3 elution media. MATERIAL AND METHODS Three bulk-fill (SDR® (SDR), X-tra base (XB) and BEAUTI...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Łagocka R,Mazurek-Mochol M,Jakubowska K,Bendyk-Szeffer M,Chlubek D,Buczkowska-Radlińska J

更新日期：2018-07-07 00:00:00

abstract：:BACKGROUND This study aimed to use gas chromatography-mass spectrometry (GC-MS) to identify the chemical constituents of volatile oil extracted by steam distillation from Cichorium glandulosum Boiss et Huet (CG), a traditional Uyghur medicine, and to investigate its effects on carbon tetrachloride (CCl₄)-induced hepat...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Qin DM,Wang XB,Zou N,Han C,Xu J

更新日期：2019-05-15 00:00:00

abstract：:BACKGROUND Curcumin is an antioxidant that reduces inflammation and pain. This study aimed to assess the effect of pretreatment with naproxen and liposomal curcumin compared with naproxen and curcumin solution on oxidative stress parameters and pain in a rat model of migraine. MATERIAL AND METHODS Sixty-three male Wis...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Bulboacă AE,Bolboacă SD,Bulboacă AC,Porfire AS,Tefas LR,Suciu ȘM,Dogaru G,Stănescu IC

更新日期：2019-07-09 00:00:00

abstract：BACKGROUND:We investigated the clinical value of serum levels of neuron-specific enolase (NSE) and human soluble protein-100β (S-100β) in acute cerebral infarction (ACI) patients. MATERIAL AND METHODS:A literature search of electronic databases identified relevant case-control studies that examined the correlations be...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li K,Jia J,Wang Z,Zhang S

更新日期：2015-06-30 00:00:00

abstract：:BACKGROUND This study investigated the cardioprotective effect of isosorbide dinitrate (ISDN) postconditioning against rat myocardial ischemia/reperfusion injury in vivo and provided a theoretical basis for clinical application. MATERIAL AND METHODS We randomly divided 32 Wistar rats into 4 groups: sham group, I/R (is...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhao X,Wang M,Li M,Wu N,Song D

更新日期：2019-03-02 00:00:00

abstract：:BACKGROUND The aim of this study was to compare the microbiota community structure, assess differences in intestinal bacterial types, and identify metagenomic biomarkers for disparate stages of colorectal cancer formation. MATERIAL AND METHODS A total of 160 individuals were recruited: 61 cases with non-tumor colon we...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xu K,Jiang B

更新日期：2017-09-14 00:00:00

abstract：:BACKGROUND Circular RNAs (circRNAs) are a kind of noncoding RNA with high cancer-specific expression, and great potential in regulating tumorigenesis. Among these, circRNA_100395 (circ_100395) has been reported to be downregulated in lung cancer, and participates in the process of tumor cell proliferation and metastas...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen Q,Chen Z,Cao S,Guo B,Chen Y,Feng Z,Wang J,Guo G,Chen X,Huang X

更新日期：2019-08-17 00:00:00

abstract：:BACKGROUND The prevalence of peripheral arterial disease (PAD) is increasing worldwide. Currently, there is no effective treatment for PAD. Curcumin is an ingredient of turmeric that has antioxidant, anti-inflammation, and anticancer properties. In the present study we investigated the potential effect of curcumin in ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu Y,Chen L,Shen Y,Tan T,Xie N,Luo M,Li Z,Xie X

更新日期：2016-06-15 00:00:00

abstract：:BACKGROUND Oxidative stress in myocardial ischemia results in cardiomyocyte apoptosis. The expression of microRNA-141-3p (miR-141-3p) and the 105 kD toll-like receptor protein (TLR), RP105, have been identified in cardiomyocytes in vitro. This study aimed to investigate the effects of hypoxia in H9c2 rat cardiomyoblas...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Qin Q,Cui L,Zhou Z,Zhang Z,Wang Y,Zhou C

更新日期：2019-09-18 00:00:00

abstract：:BACKGROUND A urine albumin to creatinine ratio (UACR) >30 mg/g is considered to represent albuminuria, but in type 2 diabetes mellitus, even low-grade albuminuria is associated with increased risk of cardiovascular disease. This study aimed to investigate the effects of metformin and acarbose treatment on urine albumi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Pan Q,Xu Y,Yang N,Gao X,Liu J,Yang W,Wang G

更新日期：2018-12-10 00:00:00

abstract：:BACKGROUND Heterozygous beta thalassemia (HBT) has been proposed to increase the risk of developing autoimmune disease. Our aim in this study was to examine the prevalence of HBT among multiple sclerosis (MS) patients. MATERIAL AND METHODS HBT frequency was investigated in our MS group (243 patients with MS). Hemoglob...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Cikrikcioglu MA,Ozcan ME,Halac G,Gultepe I,Celik K,Sekin Y,Eser EE,Burhan S,Cetin G,Uysal O

更新日期：2016-12-11 00:00:00

abstract：BACKGROUND:The conditions encountered during military service in Afghanistan create number of different medical problems, resulting in interruptions in the performance of soldiers and even evacuation to the home country. A search of the literature yielded no comprehensive studies of medical problems of any single natio...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ziemba R

更新日期：2012-07-01 00:00:00

abstract：:BACKGROUND Chronic hypertension changes the function and structure of the heart and blood vessels. This study aimed to explore the role of the NOD1/Rip2 (nucleotide-binding oligomerization domain 1/receptor-interacting protein 2) signaling pathway in myocardial remodeling in spontaneously hypertensive rats (SHRs). MAT...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu FY,Fang BQ,Sun LM,Zhang XZ,Liu JL,Yang Y,Zhang WH,Wang XL,Ding YC

更新日期：2020-08-28 00:00:00

abstract：:BACKGROUND Radiotherapy is explicitly indicated as one of the excluding factors in diagnosing overactive bladder syndrome (OAB). Nevertheless, symptoms of OAB such as urgent episodes, incontinence, pollakiuria, and nocturia, which are consequences of irradiation, led us to test the effectiveness of VESIcare®/Solifenac...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jaszczyński J,Kojs Z,Stelmach A,Wohadło Ł,Łuczyńska E,Heinze S,Rys J,Jakubowicz J,Chłosta P

更新日期：2016-07-30 00:00:00

abstract：BACKGROUND:Adequate persistence of oral antidiabetic treatment is highly important to achieve proper glycemic control in patients with type 2 diabetes. The aim of this study was to evaluate the persistence of initial treatment with metformin and/or sulphonylureas in patients with type 2 diabetes. MATERIAL/METHODS:The ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jermendy G,Wittmann I,Nagy L,Kiss Z,Rokszin G,Abonyi-Tóth Z,Katona L,Paragh G,Karádi I,Merkely B

更新日期：2012-02-01 00:00:00

abstract：:BACKGROUND Patients with diabetes mellitus (DM) commonly receive statins to suppress vulnerability to adverse cardiovascular events. It has been clinically proven that hepatotoxicity is one of the most severe adverse effects of statins. MATERIAL AND METHODS We constructed diabetic rat models by feeding rats with high-...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zeng H,Liu Z

更新日期：2019-08-17 00:00:00

abstract：:BACKGROUND Esophageal squamous cell carcinoma (ESCC), a major histological subtype of esophageal cancer, is a common cause of tumor-related deaths in the world. Due to the lack of understanding of the pathogenesis of ESCC, its clinical treatment is still a big challenge. In the present study, we aimed to identify an E...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang X,Gu M,Ju Y,Zhou J

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:The increased permeability of the glomerular capillary wall in adriamycin nephropathy may be mediated by increased generation of free radicals, possibly also by the non-enzymatic production of isoprostanes induced by oxidative stress. ACE inhibitors and angiotensin II antagonists may reduce proteinuria, perh...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Tesar V,Zima T,Jirsa M Jr,Crkovská J,Stípek S,Vernerová Z,Seráková M

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:The purpose of this article is to point out significant differences in how mental images are processed by post-stroke patients with left and right hemisphere damage. The issues involved are of theoretical importance because of the light shed on the modularity of cerebral functions, especially the imagination...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Pachalska M,Talar J,Brodziak A,MacQueen BD

更新日期：2001-07-01 00:00:00

abstract：:BACKGROUND Er-Miao-San (EMS) is used in traditional Chinese medicine. This study aimed to investigate the effect of different elution fractions of EMS on acute inflammation induced by carrageenan in the rat paw and the possible mechanisms of action. MATERIAL AND METHODS Different aqueous fractions of EMS added to an A...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Dai X,Ding M,Zhang W,Xuan Z,Liang J,Yang D,Zhang Q,Su B,Zhu H,Jia X

更新日期：2019-10-23 00:00:00

abstract：BACKGROUND:The prevalence of pressure ulcers (PUs) ranges from 1 to 18% of in-patients and from 3 to 28% in long-term settings. The aim of our study was to verify how comorbidity and frailty influenced the course of PUs in a population of elderly subjects hospitalized in a long-term care setting. MATERIAL/METHODS:The ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Donini LM,De Felice MR,Tagliaccica A,De Bernardini L,Cannella C

更新日期：2005-07-01 00:00:00