Abstract：
BACKGROUND:Umbilical cord infection caused many neonatal deaths before aseptic techniques were used. OBJECTIVES:The objective of this review was to assess the effects of topical cord care in preventing cord infection, illness and death. SEARCH STRATEGY:We searched the Cochrane Pregnancy and Childbirth Group trials register, the Cochrane Controlled Trials Register (Cochrane Library issue 4, 1997) and Medline. We also contacted experts in the field. SELECTION CRITERIA:Randomised and quasi-randomised trials of topical cord care compared with no routine care, and comparisons between different forms of care. DATA COLLECTION AND ANALYSIS:Two reviewers assessed trial quality and extracted data. MAIN RESULTS:Ten studies were included, all from developed countries. No systemic infections or deaths were observed in any of the studies reviewed. Cord and other skin infections within six weeks of observation were not affected by use of antiseptics. There was a trend to reduced colonization with antibiotics compared to antiseptics and no treatment. Antiseptics prolonged the time to cord separation. Use of antiseptics was associated with a reduction in maternal concern about the cord. REVIEWER'S CONCLUSIONS:Simply keeping the cord clean appears to be as effective and safe as using antibiotics or antiseptics.
journal_name
Cochrane Database Syst Revjournal_title
The Cochrane database of systematic reviewsauthors
Zupan J,Garner Pdoi
10.1002/14651858.CD001057keywords:
subject
Has Abstractpub_date
2000-01-01 00:00:00pages
CD001057issue
2issn
1469-493Xpii
CD001057pub_type
杂志文章,评审abstract：BACKGROUND:Oxytocin is the commonest induction agent used worldwide. It has been used alone, in combination with amniotomy or following cervical ripening with other pharmacological or non-pharmacological methods. Prior to the introduction of prostaglandin agents oxytocin was used as a cervical ripening agent as well. I...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD003246
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:Hereditary haemochromatosis is a genetic disorder related to proteins involved in iron transport, resulting in iron load and deposition of iron in various tissues of the body. This iron overload leads to complications including liver cirrhosis (and related complications such as liver failure and hepatocellul...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD011647.pub2
更新日期：2017-03-08 00:00:00
abstract：BACKGROUND:Breathlessness is one of the most common symptoms experienced in the advanced stages of malignant and non-malignant disease. Benzodiazepines are widely used for the relief of breathlessness in advanced diseases and are regularly recommended in the literature. However, the evidence for their use for this symp...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD007354.pub2
更新日期：2010-01-20 00:00:00
abstract：BACKGROUND:Epithelial ovarian cancer presents at an advanced stage in the majority of patients. These women require chemotherapy and surgery for optimal treatment. Conventional treatment is to perform surgery first and then give chemotherapy. However, it is important to determine whether there is any advantage to using...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD005343.pub2
更新日期：2007-10-17 00:00:00
abstract：BACKGROUND:Despite evidence supporting the effectiveness of diabetic retinopathy screening (DRS) in reducing the risk of sight loss, attendance for screening is consistently below recommended levels. OBJECTIVES:The primary objective of the review was to assess the effectiveness of quality improvement (QI) intervention...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD012054.pub2
更新日期：2018-01-15 00:00:00
abstract：BACKGROUND:Hallux valgus is classified as an abnormal deviation of the great toe (hallux) towards the midline of the foot. OBJECTIVES:To identify and evaluate the evidence from randomised trials of interventions used to correct hallux valgus. SEARCH STRATEGY:We searched the Cochrane Bone, Joint and Muscle Trauama Gro...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD000964.pub3
更新日期：2009-04-15 00:00:00
abstract：BACKGROUND:Acquired haemophilia A is a rare bleeding disorder caused by the development of specific autoantibodies against coagulation factor VIII. Rituximab may be an alternative approach to the treatment of acquired haemophilia by eradicating FVIII autoantibodies. OBJECTIVES:To assess and summarise the efficacy and ...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD011907.pub2
更新日期：2016-07-08 00:00:00
abstract：BACKGROUND:Malignant gastric outlet obstruction is the clinical and pathological consequence of cancerous disease causing a mechanical obstruction to gastric emptying. It usually occurs when malignancy is at an advanced stage; therefore, people have a limited life expectancy. It is of paramount importance to restore or...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD012506.pub2
更新日期：2018-05-30 00:00:00
abstract：BACKGROUND:Asymptomatic retinal breaks and lattice degeneration are visible lesions that are risk factors for later retinal detachment. Retinal detachments occur when fluid in the vitreous cavity passes through tears or holes in the retina and separates the retina from the underlying retinal pigment epithelium. Creatio...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD003170.pub4
更新日期：2014-09-05 00:00:00
abstract：BACKGROUND:Extramedullary fixation of hip fractures refers to the application of a plate and screws to the lateral side of the proximal femur. OBJECTIVES:To compare different types of extramedullary fixation implants for the surgical treatment of extracapsular hip fracture in adults. SEARCH STRATEGY:We searched the C...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD000339
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:Randomized trials have shown that the neonatal mortality rate of low birth-weight babies can be reduced by keeping them warm. For low birth-weight babies nursed in incubators, warm conditions may be achieved either by heating the air to a desired temperature, or by servo-controlling the baby's body temperatu...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD001074
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Previous systematic reviews and meta-analyses consistently show the positive effect of exercise-based rehabilitation for heart failure (HF) on exercise capacity; however, the direction and magnitude of effects on health-related quality of life, mortality and hospital admissions in HF remain less certain. Thi...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD003331.pub4
更新日期：2014-04-27 00:00:00
abstract：BACKGROUND:This review updates part of an earlier Cochrane Review titled "Pregabalin for acute and chronic pain in adults", and considers only neuropathic pain (pain from damage to nervous tissue). Antiepileptic drugs have long been used in pain management. Pregabalin is an antiepileptic drug used in management of chro...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析
doi：10.1002/14651858.CD007076.pub3
更新日期：2019-01-23 00:00:00
abstract：BACKGROUND:Osteoporosis is a condition resulting in an increased risk of skeletal fractures due to a reduction in the density of bone tissue. Treatment of osteoporosis typically involves the use of pharmacological agents. In general it is thought that disuse (prolonged periods of inactivity) and unloading of the skelet...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD000333.pub2
更新日期：2011-07-06 00:00:00
abstract：BACKGROUND:Systemic corticosteroid therapy is central to the management of acute asthma The use of inhaled corticosteroids may also be beneficial in this setting. OBJECTIVES:To determine the benefit of inhaled corticosteroids for the treatment of patients with acute asthma managed in the emergency department (ED). SE...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD002308
更新日期：2003-01-01 00:00:00
abstract：BACKGROUND:Lactoferrin, a normal component of human colostrum and milk, can enhance host defenses and may be effective for prevention of sepsis and necrotizing enterocolitis (NEC) in preterm neonates. OBJECTIVES:Primary objective 1. To assess the safety and effectiveness of lactoferrin supplementation to enteral feeds...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD007137.pub5
更新日期：2017-06-28 00:00:00
abstract：BACKGROUND:Long-acting inhaled beta2-adrenergic agonists are recommended as 'add-on' medication to inhaled corticosteroids in the maintenance therapy of asthmatic adults and children aged two years and above. OBJECTIVES:To quantify in asthmatic patients the safety and efficacy of the addition of long-acting beta2-agon...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD005535
更新日期：2005-10-19 00:00:00
abstract：BACKGROUND:Routine use of caesarean section for breech presentation is widespread. However, poor outcomes after breech birth might be the result of underlying conditions causing breech presentation rather than damage during delivery. OBJECTIVES:The objective of this review was to assess the effects of planned caesarea...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD000166
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:Electromechanical- and robot-assisted gait-training devices are used in rehabilitation and might help to improve walking after stroke. This is an update of a Cochrane Review first published in 2007 and previously updated in 2017. OBJECTIVES:Primary • To determine whether electromechanical- and robot-assiste...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析
doi：10.1002/14651858.CD006185.pub5
更新日期：2020-10-22 00:00:00
abstract：BACKGROUND:Eye movement disorders may affect over 70% of stroke patients. These eye movement disorders can result in difficulty maintaining the normal ocular position and difficulty moving the eyes appropriately. The resulting functional disabilities include a loss of depth perception, reduced hand-to-eye co-ordination...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD008389.pub2
更新日期：2011-10-05 00:00:00
abstract：BACKGROUND:Approximately 25% of adults regularly experience heartburn, a symptom of gastro-oesophageal reflux disease (GORD). Most patients are treated empirically (without specific diagnostic evaluation e.g. endoscopy. Among patients who have an upper endoscopy, findings range from a normal appearance, mild erythema t...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD002095.pub4
更新日期：2010-11-10 00:00:00
abstract：BACKGROUND:Chronic pulmonary infection is a hallmark of lung disease in cystic fibrosis. Infections dominated by organisms of the Burkholderia cepacia complex, a group of at least 18 closely-related species of gram-negative bacteria, are particularly difficult to treat. These infections may be associated with a fulmina...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章
doi：10.1002/14651858.CD009529.pub4
更新日期：2020-04-02 00:00:00
abstract：BACKGROUND:Invasive fungal infection is an increasingly common cause of mortality and morbidity in very low birth weight infants. As the diagnosis is often difficult, and treatment is often delayed, there is a need to assess whether antifungal prophylaxis is beneficial. OBJECTIVES:To assess whether prophylactic intrav...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD003850.pub2
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND:The anti-inflammatory effects of n-3 (omega-3 fatty acids, fish oil) have been suggested to be beneficial in chronic inflammatory disorders such as inflammatory bowel disease. OBJECTIVES:To systematically review the efficacy and safety of n-3 for maintaining remission in Crohn's disease (CD). SEARCH STRATE...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD006320.pub2
更新日期：2007-04-18 00:00:00
abstract：BACKGROUND:Couple therapy for depression has the twofold aim of modifying negative interaction patterns and increasing mutually supportive aspects of intimate relationships, changing the interpersonal context of depression. Couple therapy is included in several guidelines among the suggested treatments for depression. ...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD004188.pub3
更新日期：2018-06-08 00:00:00
abstract：BACKGROUND:Glutamine is a conditionally essential amino acid. Endogenous biosynthesis may be insufficient for tissue needs in states of metabolic stress. Evidence exists that glutamine supplementation improves clinical outcomes in critically ill adults. It has been suggested that glutamine supplementation may also bene...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD001457.pub5
更新日期：2016-01-12 00:00:00
abstract：BACKGROUND:Excision of the transformation zone of the cervix is the most commonly used approach to treat cervical precancerous lesions (cervical intraepithelial neoplasia (CIN)) to reduce the risk of developing cervical cancer. As the excision of the transformation zone leaves a raw area on the cervix, there is a risk ...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD009957.pub2
更新日期：2017-01-21 00:00:00
abstract：BACKGROUND:A significant proportion of patients starting dialysis do so with a temporary or tunnelled haemodialysis catheter. Insertion of these catheters can be achieved either by using the anatomical landmarks for the veins into which they are inserted or using ultrasound guidance. It has been suggested that the use ...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1002/14651858.CD005279.pub4
更新日期：2011-11-09 00:00:00
abstract：BACKGROUND:The management of pressure ulcers involves several interventions ranging from pressure-relieving measures such as repositioning, to treatments that can include reconstructive surgery. Such surgery may be considered for recalcitrant wounds when full thickness skin loss arises and deeper structures such as mus...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD012032.pub2
更新日期：2016-12-06 00:00:00
abstract：BACKGROUND:Serum monoclonal anti-Myelin Associated Glycoprotein antibodies may be pathogenic in some patients with IgM paraprotein and demyelinating neuropathy. Immunotherapies aimed at reducing the level of these antibodies might be expected to be of benefit in the treatment of the neuropathy. Many potential therapies...
journal_title：The Cochrane database of systematic reviews
pub_type： 杂志文章,评审
doi：10.1002/14651858.CD002827
更新日期：2003-01-01 00:00:00
