Abstract：
:Transcranial magnetic stimulation (TMS) has quickly progressed from a technical curiosity to a bona-fide tool for neurological research. The impetus has been due to the promising results obtained when using TMS to uncover neural processes in normal human subjects, as well as in the treatment of intractable neurological conditions, such as stroke, chronic depression and epilepsy. The basic principle of TMS is that most neuronal axons that fall within the volume of magnetic stimulation become electrically excited, trigger action potentials and release neurotransmitter into the postsynaptic neurons. What happens afterwards remains elusive, especially in the case of repeated stimulation. Here we discuss the likelihood that certain TMS protocols produce long-term changes in cortical synapses akin to long-term potentiation and long-term depression of synaptic transmission. Beyond the synaptic effects, TMS might have consequences on other neuronal processes, such as genetic and protein regulation, and circuit-level patterns, such as network oscillations. Furthermore, TMS might have non-neuronal effects, such as changes in blood flow, which are still poorly understood.
journal_name
J Neuroeng Rehabiljournal_title
Journal of neuroengineering and rehabilitationauthors
Huerta PT,Volpe BTdoi
10.1186/1743-0003-6-7subject
Has Abstractpub_date
2009-03-02 00:00:00pages
7issn
1743-0003pii
1743-0003-6-7journal_volume
6pub_type
杂志文章,评审abstract：:BACKGROUND: Monitoring body kinematics has fundamental relevance in several biological and technical disciplines. In particular the possibility to exactly know the posture may furnish a main aid in rehabilitation topics. In the present work an innovative and unobtrusive garment able to detect the posture and the movem...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/1743-0003-2-8
更新日期：2005-03-02 00:00:00
abstract：BACKGROUND:Understanding how prostheses are used in everyday life is central to the design, provision and evaluation of prosthetic devices and associated services. This paper reviews the scientific literature on methodologies and technologies that have been used to assess the daily use of both upper- and lower-limb pro...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/s12984-020-00711-4
更新日期：2020-07-14 00:00:00
abstract：BACKGROUND:Support for rehabilitation research at the National Institutes of Health (NIH) is robust and evolving. Since the time of its Blue Ribbon Panel on Rehabilitation Research, NIH has participated in several initiatives to coordinate the science and advance the field. DISCUSSION:Collaborative teams must continue...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 信件
doi：10.1186/s12984-020-00696-0
更新日期：2020-05-29 00:00:00
abstract：BACKGROUND:Chronic upper limb motor impairment is a common outcome of stroke. Therapeutic training can reduce motor impairment. Recently, a growing interest in evaluating motor training provided by robotic assistive devices has emerged. Robot-assisted therapy is attractive because it provides a means of increasing prac...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/s12984-017-0335-x
更新日期：2017-12-06 00:00:00
abstract：BACKGROUND:Virtual reality (VR) is not commonly used in clinical rehabilitation, and commercial VR gaming systems may have mixed effects in patients with stroke. Therefore, we developed RehabMaster™, a task-specific interactive game-based VR system for post-stroke rehabilitation of the upper extremities, and assessed i...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1186/1743-0003-11-32
更新日期：2014-03-06 00:00:00
abstract：BACKGROUND:Cervical spondylotic myelopathy (CSM) is a degenerative cervical disease in which the spinal cord is compressed. Patients with CSM experience balance disturbance because of impaired proprioception. The weighting of the sensory inputs for postural control in patients with CSM is unclear. Therefore, this study...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/s12984-019-0564-2
更新日期：2019-07-25 00:00:00
abstract：BACKGROUND:The overall goal of this paper was to investigate approaches to controlling active participation in stroke patients during robot-assisted gait therapy. Although active physical participation during gait rehabilitation after stroke was shown to improve therapy outcome, some patients can behave passively durin...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/1743-0003-8-14
更新日期：2011-03-23 00:00:00
abstract：BACKGROUND:Powered exoskeleton can improve the mobility for people with movement deficits by providing mechanical support and facilitate the gait training. This pilot study evaluated the effect of gait training using a newly developed powered lower limb exoskeleton robot for individuals with complete spinal cord injury...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/s12984-018-0355-1
更新日期：2018-03-05 00:00:00
abstract：BACKGROUND:Previous studies demonstrated that stroke survivors have a limited capacity to increase their walking speeds beyond their self-selected maximum walking speed (SMWS). The purpose of this study was to determine the capacity of stroke survivors to reach faster speeds than their SMWS while walking on a treadmill...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/1743-0003-9-80
更新日期：2012-10-11 00:00:00
abstract：BACKGROUND:Although several studies have investigated the outcomes after distal hamstring lengthening (DHL), no study has undertaken an approach that included all or most of the important factors that could influence the results. This study was performed to evaluate the outcomes after DHL and analyze the factors that i...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/s12984-017-0296-0
更新日期：2017-08-14 00:00:00
abstract：BACKGROUND:There is a paucity of information regarding visuospatial (VS) and visuomotor (VM) task performance in patients with chronic right fronto-parietal lobe stroke, as the majority of knowledge to date in this realm has been gleaned from acute stroke patients. The goal of this paper is to determine how VS and VM p...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/1743-0003-10-20
更新日期：2013-02-13 00:00:00
abstract：BACKGROUND:Quantitative evaluation of position control ability in stroke patients is needed. Here we report a demonstration of position control ability assessment and test-retest reliability during squat-stand activity on a new system in hemiparetic patients and controls. METHODS:Sixty-two healthy adults and thirty-fo...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/1743-0003-10-37
更新日期：2013-04-15 00:00:00
abstract：BACKGROUND:There is a need for effective and early functional rehabilitation of patients with gait and balance problems including those with spinal cord injury, neurological diseases and recovering from hip fractures, a common consequence of falls especially in the elderly population. Gait training in these patients us...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/1743-0003-4-25
更新日期：2007-07-10 00:00:00
abstract：BACKGROUND:Functional Electrical Stimulation (FES) cycling can benefit health and may lead to neuroplastic changes following incomplete spinal cord injury (SCI). Our theory is that greater neurological recovery occurs when electrical stimulation of peripheral nerves is combined with voluntary effort. In this pilot stud...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 临床试验,杂志文章
doi：10.1186/s12984-019-0619-4
更新日期：2019-11-27 00:00:00
abstract：BACKGROUND:Mobile health monitoring using wearable sensors is a growing area of interest. As the world's population ages and locomotor capabilities decrease, the ability to report on a person's mobility activities outside a hospital setting becomes a valuable tool for clinical decision-making and evaluating healthcare ...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/s12984-016-0114-0
更新日期：2016-01-20 00:00:00
abstract：BACKGROUND:Motivation is an important factor in rehabilitation and frequently used as a determinant of rehabilitation outcome. Several factors can influence patient motivation and so improve exercise adherence. This paper presents the design of two robot devices for use in the rehabilitation of upper limb movements, th...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 临床试验,杂志文章
doi：10.1186/1743-0003-4-3
更新日期：2007-02-19 00:00:00
abstract：BACKGROUND:Epidural stimulation of the spinal cord can be used to enable stepping on a treadmill (electrical enabling motor control, eEmc) after a complete mid-thoracic spinal cord transection in adult rats. Herein we have studied the effects of eEmc using a sub-threshold intensity of stimulation combined with spontane...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/1743-0003-10-108
更新日期：2013-10-24 00:00:00
abstract：BACKGROUND:Add-on robot-mediated therapy has proven to be more effective than conventional therapy alone in post-stroke gait rehabilitation. Such robot-mediated interventions routinely use also visual biofeedback tools. A better understanding of biofeedback content effects when used for robotic locomotor training may i...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12984-019-0558-0
更新日期：2019-07-23 00:00:00
abstract：BACKGROUND:Previous studies have assessed the effects of perturbation training on balance after stroke. However, the perturbations were either applied while standing or were small in amplitude during gait, which is not representative of the most common fall conditions. The perturbations were also combined with other ch...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12984-020-00707-0
更新日期：2020-06-17 00:00:00
abstract：BACKGROUND:Promising studies have shown that the gait symmetry of individuals with hemiparesis due to brain lesions, such as stroke, can improve through motor adaptation protocols forcing patients to use their affected limb more. However, little is known about how to facilitate this process. Here we asked if increasing...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/s12984-020-00698-y
更新日期：2020-06-03 00:00:00
abstract：BACKGROUND:There is an important need to better understand the activities of individual patients with stroke outside of structured therapy since this activity is likely to have a profound influence on recovery. A case-study approach was used to examine the activity levels and associated physiological load of patients w...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/1743-0003-4-41
更新日期：2007-10-26 00:00:00
abstract：:Loss of physical mobility makes maximal participation in desired activities more difficult and in the worst case fully prevents participation. This paper surveys recent work in assistive technology to improve mobility for persons with a disability, drawing on examples observed during a tour of academic and industrial ...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章,评审
doi：10.1186/1743-0003-9-20
更新日期：2012-04-20 00:00:00
abstract：BACKGROUND:While upper-extremity movement in individuals with neurological disorders such as stroke and spinal cord injury (SCI) has been studied for many years, the effects of spasticity on arm movement have been poorly quantified. The present study is designed to characterize the nature of impaired arm movements asso...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/1743-0003-4-45
更新日期：2007-11-29 00:00:00
abstract：BACKGROUND:Loss of hand function following high level spinal cord injury (SCI) is perceived as a high priority area for rehabilitation. Following discharge, it is often impractical for the specialist care centre to provide ongoing therapy for people living with chronic SCI at home, which can lead to further deteriorati...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 临床试验,杂志文章
doi：10.1186/s12984-020-00660-y
更新日期：2020-03-05 00:00:00
abstract：BACKGROUND:Upper limb assistive devices can compensate for muscular weakness and empower the user in the execution of daily activities. Multiple devices have been recently proposed but there is still a lack in the scientific comparison of their efficacy. METHODS:We conducted a cross-over multi-centric randomized contr...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/s12984-020-00794-z
更新日期：2021-01-06 00:00:00
abstract：BACKGROUND:Rehabilitation is crucial for maximizing recovery after stroke. Rehabilitation activities that are fun and rewarding by themselves can be more effective than those who are not. Gamification with virtual reality (VR) exploits this principle. This single-case design study probes the potential for using commerc...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/s12984-020-00788-x
更新日期：2020-11-23 00:00:00
abstract：BACKGROUND:KINARM end point robotic testing on a range of tasks evaluating sensory, motor and cognitive function in children/adolescents with no neurologic impairment has been shown to be reliable. The objective of this study was to determine whether differences in baseline performance on multiple robotic tasks could b...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/s12984-016-0195-9
更新日期：2016-10-12 00:00:00
abstract：BACKGROUND:Powered wheelchair (PW) training involving combined navigation and reaching is often limited or unfeasible. Virtual reality (VR) simulators offer a feasible alternative for rehabilitation training either at home or in a clinical setting. This study evaluated a low-cost magnetic-based hand motion controller a...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/s12984-016-0112-2
更新日期：2016-01-19 00:00:00
abstract：:Despite upper extremity function playing a crucial role in maintaining one's independence in activities of daily living, upper extremity impairments remain one of the most prevalent post-stroke deficits. To enhance the upper extremity motor recovery and performance among stroke survivors, two training paradigms in the...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/s12984-018-0408-5
更新日期：2018-07-04 00:00:00
abstract：BACKGROUND:To promote early rehabilitation of walking, gait training can start even when patients are on bed rest. Supine stepping in the early phase after injury is proposed to maximise the beneficial effects of gait restoration. In this training paradigm, mechanical loading on the sole of the foot is required to mimi...
journal_title：Journal of neuroengineering and rehabilitation
pub_type： 杂志文章
doi：10.1186/1743-0003-11-159
更新日期：2014-11-28 00:00:00
