Abstract：
:The aim of the study was to investigate, in adult patients after successful repair of aortic coarctation, potential relationships between B-type natriuretic peptide levels and exercise capacity and the following factors: arterial hypertension, residual stenosis of the ascending aorta, and age at the time of surgery. The study group comprised 74 patients (45 men) aged 19 to 61 years (mean, 31.2 +/- 9.8 yr), who had undergone surgery at the age of 0.5 to 34 years (mean, 10.4 +/- 6.8 yr). The surgery was performed between 5 and 34 years earlier (mean, 21.4 +/- 6.2 yr). A subgroup with residual aortic stenosis (significant when > or =25 mmHg) comprised 32 patients; a subgroup without residual stenosis comprised 42 patients. Patients were also divided into subgroups without arterial hypertension (n=32), with exercise-induced arterial hypertension (n=10), and with persistent arterial hypertension (n=32). All patients were in New York Heart Association functional class I. The control group comprised 30 healthy subjects (18 men) aged 26 to 46 years (mean, 32.2 +/- 6.6 yr). After testing exercise capacity in accordance with a modified Bruce protocol, we concluded that the exercise capacity of adults is reduced after surgical repair of aortic coarctation. This reduction is more pronounced in patients who have arterial hypertension, but it is unaffected by residual stenosis of the descending aorta. Serum B-natriuretic peptide concentrations, as determined by immunoradiometric assay, are significantly elevated, which may result from pressure overload of the left ventricle or from residual myocardial lesions due to coarctation repair at an older age.
journal_name
Tex Heart Inst Jjournal_title
Texas Heart Institute journalauthors
Trojnarska O,Gwizdala A,Lanocha M,Katarzynska A,Katarzynski S,Oko-Sarnowska Z,Szyszka A,Chmara Esubject
Has Abstractpub_date
2007-01-01 00:00:00pages
412-9issue
4eissn
0730-2347issn
1526-6702journal_volume
34pub_type
杂志文章abstract：:Thrombosis involving a permanent infusion catheter in the subclavian vein and superior vena cava is relatively common, especially in cancer patients. Edema of the arms and head is a well-known clinical consequence of this thrombosis, with an intrinsic risk of pulmonary embolism; however, systemic embolization into the...
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journal_title：Texas Heart Institute journal
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journal_title：Texas Heart Institute journal
pub_type： 杂志文章
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journal_title：Texas Heart Institute journal
pub_type： 杂志文章,评审
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journal_title：Texas Heart Institute journal
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pub_type： 杂志文章
doi：
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