Abstract：
:Whipple's Disease is a rare multisystemic disease caused by Gram-positive bacillus, Tropheryma whippelii, family of Actinobacterias and group of Actinomycetes. Because the disease is rare and has different forms of presentation the diagnosis comes frequently late. The authors present the case of a white man, 50 years old, admitted with a clinical picture characterized by weight loss, abdominal pain, ascites, diarrhea. He suffered of arthralgias for four years. The diagnosis was made by biopsy of mesenteric adenopathies and liver, during the laparotomy. The biopsy specimens showed numerous aggregates of foamy macrophages containing granular periodic acid-shiff (PAS)--positive material, diastase resistant. Afterwards, the bacillus was identified by electronic microscopy. The patient was treated with trimethoprim-sulfamethoxazole. Symptoms disappeared and biological values returned to normal. The authors present the case and discuss auxiliary exams, differential diagnosis, follow-up, treatment and review the main characteristics of the disease.
journal_name
Acta Med Portjournal_title
Acta medica portuguesaauthors
Carneiro AC,Lima P,Barbosa IP,Chaves FCsubject
Has Abstractpub_date
2004-11-01 00:00:00pages
481-6issue
6eissn
0870-399Xissn
1646-0758journal_volume
17pub_type
杂志文章abstract：:Wernicke Encephalopathy (WE) is a severe neurological disease caused by vitamin B1 (thiamine) deficiency, which is potentially treatable if early diagnosed. This is the clinical case of a young female patient, with renal insufficiency on haemodialysis, who has been submitted to an abdominal surgery. After the interven...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
abstract：INTRODUCTION:To analyze the cesarean section rate evolution in a tertiary hospital and the main indications for cesarean section. MATERIAL AND METHODS:A retrospective study was conducted at a major academic hospital and included 5 751 women who had a cesarean section from 2005 to 2011. The rates of overall, primary an...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2013-11-01 00:00:00
abstract：:Kikuchi and Fujimoto's disease, also known as histiocytic necrotizing lymphadenopathy, is a rare and benign disorder of the lymph nodes of young adults. The etiology of this disease is unknown, an autoimmune mechanism has been suggested, although some cases of association with several viruses has been described. We re...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2005-05-01 00:00:00
abstract：:Elastosis perfurans serpiginosa is a rare perforating dermatosis found primarily in adolescents and young adults, characterized by transepidermal elimination of abnormal elastic fibers. The only drug known capable of inducing elastosis perfurans serpiginosa is D-penicillamine. We report the case of a 52 year-old woman...
journal_title：Acta medica portuguesa
pub_type：
doi：10.20344/amp.6749
更新日期：2016-03-01 00:00:00
abstract：:A case of oesophageal basaloid carcinoma is reported. The disease was revealed as a brain metastasis and was found ad initium to be in an advanced stage, with evidence of brain, lung and liver metastasis. The treatment performed was palliative subtotal oesophagectomy followed by roentgen therapy. A year and a half lat...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：1995-09-01 00:00:00
abstract：INTRODUCTION AND AIM:In Portugal, there is very few experience in pediatric retroperitoneoscopy. The authors present the first Portuguese series of retroperitoneal laparoscopic nephrectomies (RLN) in children younger than nine years-old, as well as a literature review about the theme. MATERIAL AND METHODS:Retrospectiv...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVES:This study was undertaken to assess the value of Cockroft-Gault Formula (FCG) in the patients of an Internal Medicine ward. METHODS:FCG was compared with creatinine clearance (DC) adjusted for corporal area. Serum creatinine was measured after 24 h urine collection and 8 h fast. By the subtraction of FCG fr...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1998-08-01 00:00:00
abstract：:The pathogenesis of cholestasis, bilirubin encephalopathy, and Alzheimer's disease appears to result from accumulation of diverse cytotoxic agents, which in turn may cause apoptotic cell death. In addition, mitochondria has lately been considered as a central executioner of programmed cell death, through the release o...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2002-07-01 00:00:00
abstract：:Biomedical simulation is an effective educational complement for healthcare training, both at undergraduate and postgraduate level. It enables knowledge, skills and attitudes to be acquired in a safe, educationally orientated and efficient manner. In this context, simulation provides skills and experience that facilit...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.8403
更新日期：2016-12-30 00:00:00
abstract：:In Portugal, piroxicam is one of the most prescribed non-steroidal anti-inflammatory agents (NSAIDs) and is frequently associated to photosensitivity skin reactions, well known by all dermatologists. The authors review the physiopathology and clinical patterns of this adverse drug reaction. Importance is given to the ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：1998-11-01 00:00:00
abstract：:A retrospective study was made of the requests for bacteriological examination of urine samples by the different clinical departments of Vila Nova de Famalicão District Hospital, between July/89-June/90 and July/91-June/92. We were interested in assessing the spectrum of occurring micro-organisms in urinary tract infe...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:Malignant spinal cord compression occurs in 2.5% - 5% cancer patients. Early diagnosis and therapeutic intervention are critical for pain control and improvement of any neurological deficit. Treatment should be directed to the underlying disease together with appropriate symptom management. The case of a man with tetr...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2012-11-01 00:00:00
abstract：:Atrial septum aneurysms are an uncommon condition, underestimated before the routine use of echocardiography. Their clinical importance has increased after being associated with thromboembolic events. The authors made a review of clinical, diagnostic and therapeutic features of this entity after reporting six clinical...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1998-04-01 00:00:00
abstract：:Epidemiologic data on prevalence of bronchial asthma among childhood in the Azores have been unknown so far. In October of 1993 a study was carried out to determine the prevalence of bronchial asthma in children aged 6-12 years on the island of Faial. Nine hundred and twenty seven schoolchildren, representing more tha...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：INTRODUCTION:Adolescents are a target group for reproductive health intervention. Family physicians, gynecologists and pediatricians are the main providers of contraceptive counseling. MATERIAL AND METHODS:Correlational, cross-sectional study, approved by the ethics committee of Leiria Hospital, Portugal. Data was col...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.11088
更新日期：2019-08-01 00:00:00
abstract：:Sympathetic and parasympathetic nervous system evaluation was performed in 21 patients with rheumatoid arthritis. Every patient had autonomic nervous system (ANS) dysfunction, the parasympathetic involvement being the most frequent. ANS dysfunction may explain some manifestations and may well be the expression of a la...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：INTRODUCTION:MEN2A is an autossomal dominant cancer syndrome characterised by the presence of medullary thyroid cancer, pheochromocytoma and primary hyperparathyroidism. Germline mutations of the RET protooncogene constitute the molecular defect and can be identified in affected individuals. Genetic screening of family...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：:The authors report a case of seronegative polyarthritis resistant to the anti-inflammatory therapy in a 16-year-old male with intermittent diarrhea. A stool examination showed the presence of cysts of Giardia lamblia and an immunological study detected a partial serum IgA deficiency, including its secretory fraction. ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：1993-12-01 00:00:00
abstract：:Neurocysticercosis (NCC) is the most frequent parasitic disease of the central nervous system. Other Portuguese works showed it to be endemic in the north of our country. The purpose of this paper is to aid the characterization of NCC in the geographic area of our Institution. We retrospectively reviewed the findings ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：:Parkinson's disease (PD) is a common disorder that causes a marked decrease in the quality of life of patients and implies high costs at the social, familiar and economic levels. The diagnosis is essentially achieved on clinical grounds and there is an extensive list of possible differential diagnoses, thus being fund...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：2011-12-01 00:00:00
abstract：:Statistics is the science that studies variability in all its forms and, in essence, is an instrument that allows us to analyze variable phenomena and detect small, but nevertheless important, differences. The instrumental character of this science made Statistics a fundamental tool for the study of biological and cli...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：INTRODUCTION:Portugal is experiencing the effects of the COVID-19 pandemic since March 2020. All-causes mortality in Portugal increased during March and April 2020 compared to previous years, but this increase is not explained by COVID-19 reported deaths. The aim of this study was to analyze and consider other criteria...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.13928
更新日期：2020-06-01 00:00:00
abstract：:The objective of this manuscript is to discuss the existing barriers for the dissemination of medical guidelines, and to present strategies that facilitate the adaptation of the recommendations into clinical practice. The literature shows that it usually takes several years until new scientific evidence is adopted in ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:The Authors retrospectively studied 17 patients who have been admitted to the Infectious Diseases Clinic of Coimbra University Hospital during a four year period and whose final diagnosis was brucellar spondylitis. Clinical, epidemiological, laboratory and imaging features are analyzed, as well as those related to the...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：:Multiple risk factors for cardiovascular disorders, particularly hypercholesterolemia, are often present in hypertensive patients. Several studies have shown that antihypertensive drugs affect the lipid profile, increasing the risk of cardiovascular diseases. Here, it was investigated the lipoprotein metabolism altera...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2008-11-01 00:00:00
abstract：:Osteoporosis in men, despite being a less important public health problem than osteoporosis in women, should not be neglected as it has many deleterious effects as well as social and economic costs. Finding the cause of osteoporosis is more complex in men than in women, and prevention should be based on an early evalu...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：1995-05-01 00:00:00
abstract：:A new case of nephrotoxic effect of Maneb is related. The patient used this product as fungicide and developed a progressive illness with acute renal failure. The study by light and electron microscopy revealed severe tubular lesions that disappeared some months later with tubular cell regeneration. However, in spite ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1989-08-01 00:00:00
abstract：:The female varicocile is associated to the pelvic congestion syndrome that is described. Five patients 31 to 52 years old are presented. Four of them have continuous pelvic pain and the fifth had huge vaginal and vulvar varices. Flebography of the left ovarian vein showed retrograde flux of the dilated vein. Sclerothe...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:After the discovery of insulin and during almost an half of a century, physicians and researchers apply their efforts in a better knowledge to reduce the perinatal mortality of the offspring of the diabetic mother. The optimisation of glucose control--the main key of the management of diabetic pregnancy--and the new m...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：2002-05-01 00:00:00
abstract：:The accurate treatment of a dyslipidaemia is based on correct diagnosis. Together with the laboratory values. A good clinical interview, focusing on the family history, is the bases for a good diagnosis strategy. The author schematze the rules of etiological diagnosis of inherited defects of lipid metabolism. ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
