Abstract：
:Myocardial fibrosis can occur in patients who have hypertrophic cardiomyopathy in the absence of epicardial coronary disease. In such patients, myocardial fibrosis has been linked to a poorer prognosis than in those without fibrosis. Gadolinium-DTPA delayed-enhancement magnetic resonance imaging (de-MRI) accurately identifies regions of myocardial fibrosis. We used de-MRI to screen for myocardial fibrosis in 8 patients with nonobstructive hypertrophic cardiomyopathy that had been diagnosed by 2-dimensional echocardiography. After localization of the heart and acquisition of electrocardiographically gated cine images, gadolinium-DTPA (0.2 mmol/kg) was administered to the patient. Fifteen minutes later, de-MRI images were obtained using a T1-weighted, inversion-recovery fast, low-angle shot sequence. Images were gated to end-diastole and obtained during a single breath-hold. The inversion time was modified iteratively to obtain maximal nulling of the signal from the ventricular myocardium. Regions of myocardium with abnormally high signals (>300% of remote normal myocardium) were designated as fibrotic. Eight patients with hypertrophic cardiomyopathy underwent de-MRI. The mean age was 52 years, the mean left ventricular mass was 201 grams, and the mean ejection fraction was 0.68. In the 6 patients with recent clinical deterioration, de-MRI showed clearly delineated areas of myocardial fibrosis; no such areas were seen in the 2 asymptomatic patients. We conclude that patients with symptomatic hypertrophic cardiomyopathy display regions of abnormal signal intensity on de-MRI that likely represent fibrosis. This technique may provide useful information in the evaluation of such patients and warrants further study.
journal_name
Tex Heart Inst Jjournal_title
Texas Heart Institute journalauthors
Wilson JM,Villareal RP,Hariharan R,Massumi A,Muthupillai R,Flamm SDsubject
Has Abstractpub_date
2002-01-01 00:00:00pages
176-80issue
3eissn
0730-2347issn
1526-6702journal_volume
29pub_type
杂志文章abstract：:Hemangiomas of the heart are extremely rare. The prognosis is quite variable, because this benign tumor may grow, involute, or stop growing; therefore, resection is usually the treatment of choice. In patients with tumors of the left atrium, percutaneous balloon mitral valvulotomy is generally contraindicated. Yet for...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:Atrial myxoma is the most common primary cardiac tumor. Patients with atrial myxoma typically present with obstructive, embolic, or systemic symptoms; asymptomatic presentation is very rare. To our knowledge, isolated association of atrial myxoma with hypertrophic cardiomyopathy has been reported only once in the Engl...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:Bone marrow-derived CD34(+) cells are a well-characterized population of stem cells that have traditionally been used clinically to reconstitute the hematopoietic system after radiation or chemotherapy. More recently, CD34(+) cells have also been shown to induce therapeutic angiogenesis in animal models of myocardial,...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章,评审
doi：
更新日期：2011-01-01 00:00:00
abstract：:In recent years, researchers have investigated the relationship between biological markers of inflammation and prognosis in patients who experience acute coronary syndromes; however, the association between plasma fibrinogen and coronary heart disease is still not clear. We studied the prognostic value of fibrinogen, ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:Acute aortic dissection is a medical emergency. Without prompt recognition and treatment, the mortality rate is high. An atypical presentation makes timely diagnosis difficult, especially if the patient is experiencing no characteristic pain. Many patients with aortic dissection are reported to have presented with var...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Assessing thromboembolic risk is crucial for proper management of patients with atrial fibrillation. Left atrial volume is a promising predictor of cardiac thrombosis. To determine whether left atrial volume can predict left atrial appendage thrombus in patients with atrial fibrillation, we conducted a prospective stu...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：10.14503/THIJ-17-6290
更新日期：2020-04-01 00:00:00
abstract：:Entrapment and fracture of coronary angioplasty hardware are rare complications of percutaneous coronary artery interventions; however, when such incidents occur, they frequently require surgical management. Percutaneous retrieval should be attempted before surgical retrieval unless hemodynamic stability is a problem....
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:In patients who have cyanosis and dyspnea that are unrelated to a cardiopulmonary cause, 1 rare possible diagnosis is methemoglobinemia. This condition is generally asymptomatic, even when the methemoglobin level is as high as 40% of the total hemoglobin value. In the patient described herein, extensive pulmonologic a...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Because of the variety of their anatomy and clinical implications, coronary anomalies tend to confuse many observers. Recently, our group and other investigators have proposed that only 1 specific type of anomaly, by means of a specific mechanism, is able to cause both symptoms of myocardial ischemia and sudden death....
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:The year 2016 was the 180th anniversary of Wilhelm Ebstein's birth and the 150th anniversary of his description of the congenital tricuspid valve malformation that came to be known as Ebstein anomaly. We present a brief history of the life and work of Dr. Wilhelm Ebstein. Despite his distinguished career, he is seemin...
journal_title：Texas Heart Institute journal
pub_type： 传,历史文章,杂志文章,评审
doi：10.14503/THIJ-16-6063
更新日期：2017-06-01 00:00:00
abstract：:We report the case of a 14-year-old boy who developed ischemic contracture of the heart after open heart surgery to correct complex congenital heart disease. Because he had no cardiac function, an extracorporeal, continuous-flow device was used to support him until he was transferred to our institution. Shortly after ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:The effects of left ventricular pseudoaneurysm following transmural myocardial infarction can be devastating; therefore, prompt diagnosis and surgical resection are warranted. We report a rare case of recurrent left ventricular pseudoaneurysm in which color-flow Doppler echocardiography was useful in establishing the ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:The aim of the study was to investigate, in adult patients after successful repair of aortic coarctation, potential relationships between B-type natriuretic peptide levels and exercise capacity and the following factors: arterial hypertension, residual stenosis of the ascending aorta, and age at the time of surgery. T...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:We report an interesting case of single right coronary artery arising from the right sinus of Valsalva and continuing distally as a rare anomalous left coronary artery. Over the 7-year course of our clinical follow-up, the right coronary artery manifested severe, progressive atherosclerotic disease in multiple sites, ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:Fulminant myocarditis is a rare but potentially life-threatening illness caused by 5-fluorouracil cardiotoxicity. Data supporting the use of extracorporeal membrane oxygenation for the treatment of fulminant myocarditis are limited. A 49-year-old, previously healthy white man, recently diagnosed with anal squamous cel...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：10.14503/THIJ-15-5100
更新日期：2016-04-01 00:00:00
abstract：:As the indications for implanting left ventricular assist devices have expanded, some patients are qualifying for device removal after myocardial recovery. Whereas explantation has been described for previous generations of devices, no standard procedures have been developed. Removal of centrifugal-flow devices has cr...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：10.14503/THIJ-19-7097
更新日期：2020-08-01 00:00:00
abstract：:We present the case of a 10-year-old girl who developed visual loss progressing to blindness after orthotopic heart transplantation and an immunosuppressive regimen of cyclosporine, azathioprine, and prednisone. Headaches and visual deterioration began 2 months after transplantation, and a diagnosis of pseudotumor cer...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:In our experience, single-stage open repair of descending thoracic or thoracoabdominal aortic aneurysms with concurrent aortic arch disease is technically feasible via a high left thoracotomy or a thoracolaparotomy. Distal aortic and antegrade brain perfusion, in combination with brain and spinal cord protection, seem...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:Heart valve repair is a biomaterial-dependent procedure, yet autogenous tissue for valvular reconstruction has to date been obtained mostly from the pericardium and fascia lata. Most clinical studies recommend valve repair as an alternative to replacement. We now put forward a hypothesis, extrapolated from hand surger...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:From 1956 through July 1981, 15 patients, ranging in age from 9 days to 20 years, underwent surgical correction of aortopulmonary (AP) window. Surface hypothermia and venous inflow occlusion were used in the first patient. In four patients, the technique for closure of AP window was similar to that for patent ductus a...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1983-03-01 00:00:00
abstract：:We sought to compare outcomes in patients > or = 60 years of age with those of their younger counterparts who underwent ventricular assist device implantation intended as a bridge to cardiac transplantation and also to identify retrospectively additional pre- and postoperative factors that might portend adverse outcom...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:Approximately 20% to 30% of patients who undergo coronary arteriography for the evaluation of chest pain are found to have normal coronary arteries. These patients have a survival rate comparable to that of the normal population, yet they continue to complain of symptoms on extended follow-up, and about half of this g...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章,评审
doi：
更新日期：1993-01-01 00:00:00
abstract：:This report describes an early diagnosis and successful correction of a disrupted "improved" Björk-Shiley prosthetic valve in the mitral position. The role of 2-Dimensional echocardiography in the diagnosis is emphasized. ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1985-03-01 00:00:00
abstract：:Between May 1976 and December 1982 (104 months), 152 patients from a total of 3592 patients who had coronary angiography at the Buffalo Veterans Administration Medical Center had coronary artery disease with left ventricular ejection fractions of 40% or below. Sixty-three patients in this group had coronary bypass sur...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1986-03-01 00:00:00
abstract：:We present the case of a 69-year-old man with a history of hypertension and a recent pelvic fracture who presented with acute chest pain, shortness of breath, and severe hypotension. The history of recent pelvic fracture and the clinical manifestations, including the sudden onset of acute respiratory distress, hypoten...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:During his work, an 18-year-old carpenter-in-training overbalanced and shot himself in the left median thorax with a nail gun. The patient was delivered to our thoracic surgery unit with a tentative diagnosis of penetrating lung trauma. An emergent computed tomogram showed a heart-penetrating nail injury. The patient ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：10.14503/THIJ-13-3405
更新日期：2014-08-01 00:00:00
abstract：:In Part 1 of this review, we discussed how plaque rupture is the most common underlying cause of most cases of unstable angina/non-ST-segment-elevation myocardial infarction (UA/NSTEMI) and how early risk stratification is vital for the timely diagnosis and treatment of acute coronary syndromes (ACS). Now, in Part 2, ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章,评审
doi：
更新日期：2010-01-01 00:00:00
abstract：:Over a 3-year period, we performed 232 consecutive percutaneous transluminal coronary angioplasty (PTCA) procedures in 171 patients, 132 (77%) of whom were men and 39 (23%) of whom were women. The patients' ages ranged from 26 to 85 years (average, 56.5 years). All of the patients had symptoms of coronary insufficienc...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1987-03-01 00:00:00
abstract：:Acute massive pulmonary embolism after cardiac surgery is very rare. Although accurate diagnosis and rapid treatment are crucial to a successful outcome, there is no standard treatment option. Thrombolytic therapy and catheter embolectomy are the usual treatment options, but they are associated with risks, especially ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:A simple technique of controlling a bleeding aortic cannulation site employing autogenous tissue is described in which 3-0 Prolene suture is placed through the lateral pericardial tissue on both sides of the aortotomy closure in a horizontal mattress fashion. This technique is advantageous because of the availability ...
journal_title：Texas Heart Institute journal
pub_type： 杂志文章
doi：
更新日期：1986-06-01 00:00:00
