Implementation of guidelines in eosinophilic esophagitis at an academic pediatric practice.

Abstract:

:Guidelines for eosinophilic esophagitis (EoE) require high-dose PPI (HD-PPI) trial to evaluate for PPI-responsive esophageal eosinophilia (PPI-REE) prior to EoE diagnosis and dedicated therapy. This involves a second esophagogastroduodenoscopy (EGD) to assess for PPI-REE. This study is to evaluate adherence to current guidelines in evaluation of PPI-REE and EoE. Retrospective review of new patients treated with HD-PPI after an index EGD showing >15 eos/hpf in esophageal biopsies. One hundred and eighty patients had an index EGD with esophageal eosinophilia of >15 eos/hpf. Of these, 97/180 (53.8%) received HD-PPI; remaining 83/180 were prescribed other interventions without a HD-PPI trial. Of the 180 patients, 143 (79.4%) patients returned for follow-up and of whom 96/143 (67.1%) underwent repeat EGD. Adherence to guidelines improves with time. Patients are vested in care.

journal_name

Dis Esophagus

authors

Harris BR,Hon E,Gupta SK

doi

10.1093/dote/doy029

subject

Has Abstract

pub_date

2018-08-01 00:00:00

issue

8

eissn

1120-8694

issn

1442-2050

pii

4994955

journal_volume

31

pub_type

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