Baicalein improves behavioral dysfunction induced by Alzheimer's disease in rats.

abstract：Purpose:Whole-exome sequencing (WES) of multiplex families is a promising strategy for identifying causative variations for common diseases. To identify rare recessive risk variations for schizophrenia, we performed a WES study in a consanguineous family with affected siblings. We then performed follow-up sequencing of...

journal_title：Neuropsychiatric disease and treatment

authors： Igeta H,Watanabe Y,Morikawa R,Ikeda M,Otsuka I,Hoya S,Koizumi M,Egawa J,Hishimoto A,Iwata N,Someya T

更新日期：2019-08-19 00:00:00

abstract：Aim of the study:Genetic (idiopathic) generalized epilepsies (GGEs) account for nearly one-third of all epilepsies. The frequency of status epilepticus (SE) in patients with GGEs has been poorly studied. Therefore, this study aimed to evaluate the frequency of different forms of SE in a cohort of patients with GGEs. M...

journal_title：Neuropsychiatric disease and treatment

authors： Bosak M,Pawełczak D,Słowik A

更新日期：2019-06-20 00:00:00

abstract：:Tourette's syndrome (TS) is a neurodevelopmental disorder that comprises vocal and motor tics associated with a high frequency of psychiatric comorbidities, which has an important impact on quality of life. The onset is mainly in childhood and the symptoms can either fade away or require pharmacological therapies asso...

journal_title：Neuropsychiatric disease and treatment

authors： Casagrande SCB,Cury RG,Alho EJL,Fonoff ET

更新日期：2019-04-29 00:00:00

abstract：:Autism spectrum disorder (ASD) is a highly complex and heterogeneous developmental disorder that affects how individuals communicate with other people and relate to the world around them. Research and clinical focus on the behavioural and cognitive manifestations of ASD, whilst important, have obscured the recognition...

journal_title：Neuropsychiatric disease and treatment

authors： Sala R,Amet L,Blagojevic-Stokic N,Shattock P,Whiteley P

更新日期：2020-06-30 00:00:00

abstract：:Recent findings in animal models of paraplegia suggest that specific nonbenzodiazepine anxiolytics may temporarily restore locomotor functions after spinal cord injury (SCI). Experiments using in vitro models have revealed, indeed, that selective serotonin receptor (5-HTR) ligands such as 5-HTR(1A) agonists, known as ...

journal_title：Neuropsychiatric disease and treatment

authors： Guertin PA

更新日期：2008-08-01 00:00:00

abstract：Background:Various personality traits mediate the association between childhood stress and depressive symptoms in adulthood. The aim of this study was to clarify the indirect effects of the experience of child maltreatment on depressive symptoms and appraisal of life events in adulthood through trait anxiety. Subjects...

journal_title：Neuropsychiatric disease and treatment

authors： Uchida Y,Takahashi T,Katayama S,Masuya J,Ichiki M,Tanabe H,Kusumi I,Inoue T

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:Anterior cingulate cortex (ACC) dysfunction is implicated in schizophrenia by numerous strands of scientific investigation. Functional neuroimaging studies of the ACC in schizophrenia have shown task-related hypo-activation, hyper-activation, and normal activation relative to comparison subjects. Interpretin...

journal_title：Neuropsychiatric disease and treatment

authors： Adams R,David AS

更新日期：2007-02-01 00:00:00

abstract：:Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by pervasive difficulties since early childhood across reciprocal social communication and restricted, repetitive interests and behaviors. Although early ASD research focused primarily on children, there is increasing recognition that...

journal_title：Neuropsychiatric disease and treatment

authors： Murphy CM,Wilson CE,Robertson DM,Ecker C,Daly EM,Hammond N,Galanopoulos A,Dud I,Murphy DG,McAlonan GM

更新日期：2016-07-07 00:00:00

abstract：:Objective: To explore the efficacy and safety of "cocktail therapy" in Parkinson's disease with dementia (PDD). Patients and methods: Sixty patients with PDD were randomly assigned to the test group (n=30) and a control group (n=30). The control group received 10 mg of donepezil hydrochloride tablets orally, once a da...

journal_title：Neuropsychiatric disease and treatment

authors： Zhang C,Zang Y,Song Q,Li H,Hu L,Zhao W,Feng S,Gu F,Zhao F,Zhang C

更新日期：2019-06-24 00:00:00

abstract：:Headaches in children and adolescents are still under-diagnosed. 75% of children are affected by primary headache by the age of 15 with 28% fitting the ICHD2 criteria of migraine. Migraine is considered a chronic disorder that can severely impact a child's daily activities, including schooling and socializing. Early r...

journal_title：Neuropsychiatric disease and treatment

authors： Kabbouche MA,Gilman DK

更新日期：2008-06-01 00:00:00

abstract：:This study evaluates the correlation between failure to develop spontaneous imitation and language skills in pervasive developmental disorders. Sixty-four children between the age of 3 and 8 years were assessed using the Autism Diagnostic Interview-Revised (ADI-R), the Childhood Autism Rating Scale (CARS), and the Aut...

journal_title：Neuropsychiatric disease and treatment

authors： De Giacomo A,Portoghese C,Martinelli D,Fanizza I,L'abate L,Margari L

更新日期：2009-01-01 00:00:00

abstract：:Pramipexole is a non-ergot dopamine agonist shown to be efficacious in the treatment of Parkinson's disease (PD). This review addresses the literature concerning pramipexole's efficacy in treating motor and non-motor symptoms in PD, its impact on the development of dyskinesias and response fluctuations, the issue of n...

journal_title：Neuropsychiatric disease and treatment

authors： Constantinescu R

更新日期：2008-04-01 00:00:00

abstract：Background:It has been suggested that autism spectrum disorder (ASD) might be a "comorbid" condition in selective mutism (SM). Methods:In this retrospective study, we examined medical records of children with SM diagnosis (n=97) at a medical center specializing in assessment of ASD. Results:Mean age for onset of SM s...

journal_title：Neuropsychiatric disease and treatment

authors： Steffenburg H,Steffenburg S,Gillberg C,Billstedt E

更新日期：2018-05-07 00:00:00

abstract：OBJECTIVE:To constitute the third revision of the guidelines for the treatment of bipolar disorder issued by the Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP 2014). METHODS:A 56-item questionnaire was used to obtain the consensus of experts regarding pharmacological treatment strategies for the va...

journal_title：Neuropsychiatric disease and treatment

authors： Woo YS,Lee JG,Jeong JH,Kim MD,Sohn I,Shim SH,Jon DI,Seo JS,Shin YC,Min KJ,Yoon BH,Bahk WM

更新日期：2015-02-26 00:00:00

abstract：Introduction:The study was designed to explore the possible adverse effects of prenatal polycyclic aromatic hydrocarbons (PAHs) on the neurodevelopment of the infants at the age of 12 months in a birth cohort in Qingdao of China. Benzo[a]pyrene (BaP)-DNA adduct level in umbilical cord blood was measured by enzyme immun...

journal_title：Neuropsychiatric disease and treatment

authors： Zhang Y,Yang Y,Zhang Q,Cui J,Rahaman A,Huang XR,Su Y,Gao R,Wang B,Baloch Z

更新日期：2019-12-02 00:00:00

abstract：:Fluvoxamine is a selective-serotonin reuptake inhibitor (SSRI) that has proved effective in large double-blind, randomized, controlled trials involving patients with social anxiety disorder (SAD), obsessive-compulsive disorder (OCD), and panic disorder. Improvements have also been demonstrated in patients with post-tr...

journal_title：Neuropsychiatric disease and treatment

authors： Irons J

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND AND METHODS:This study investigated the effects of sleep deprivation on total and partial (early and late) declarative memory and activation in the areas of the brain involved in these activities. The study included two experiments. Experiment 1 included 40 male residents of an orphanage aged 16-19 years, wh...

journal_title：Neuropsychiatric disease and treatment

authors： Tantawy AO,Tallawy HN,Farghaly HR,Farghaly WM,Hussein AS

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to ascertain the clinical characteristics of drug-induced sleep-related eating disorder (SRED). PATIENTS AND METHODS:We retrospectively reviewed the medical records of 30 patients with primary SRED (without any comorbid sleep disorders and who were not taking any possible causative me...

journal_title：Neuropsychiatric disease and treatment

authors： Komada Y,Takaesu Y,Matsui K,Nakamura M,Nishida S,Kanno M,Usui A,Inoue Y

更新日期：2016-05-26 00:00:00

abstract：:Gerstmann's syndrome encompasses the tetrad of finger agnosia, agraphia, acalculia, and right-left confusion. An elderly man with a history of several cardiovascular diseases was initially brought to the psychiatric outpatient department by his family because of worsening of recent memory, executive function, and mixe...

journal_title：Neuropsychiatric disease and treatment

authors： Chen TY,Chen CY,Yen CH,Kuo SC,Yeh YW,Chang S,Huang SY

更新日期：2013-01-01 00:00:00

abstract：Purpose:Cardiovascular and metabolic adverse events are costly to treat, and their incidence is increased amongst people with schizophrenia, with different rates observed for second-generation antipsychotics. To inform treatment choice, this study sought to estimate the lifetime costs associated with antipsychotic choi...

journal_title：Neuropsychiatric disease and treatment

authors： Kearns B,Cooper K,Cantrell A,Thomas C

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:Decreased relapse rate and slower disease progression have been reported with long-term use of immunomodulatory treatments (IMTs, interferon beta or glatiramer acetate) in relapsing-remitting multiple sclerosis. There are, however, patients who do not respond to such treatments, and they can be potential can...

journal_title：Neuropsychiatric disease and treatment

authors： Mezei Z,Bereczki D,Racz L,Csiba L,Csepany T

更新日期：2012-01-01 00:00:00

abstract：:At the time of this study, there were five known patients with Wilson disease (WD) in Iceland. The mutation, a 7-bp deletion in exon 7 on chromosome 13 for WD, is only known in Iceland. In twenty healthy Icelandic heterozygotes for WD and their age- and gender-matched controls, copper concentration in plasma, cerulopl...

journal_title：Neuropsychiatric disease and treatment

authors： Tórsdóttir G,Gudmundsson G,Kristinsson J,Snaedal J,Jóhannesson T

更新日期：2009-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) remains the main cause of disability and a major public health problem worldwide. This review focuses on the neurophysiology of TBI, and the rationale and current state of evidence of clinical application of brain stimulation to promote TBI recovery, particularly on consciousness, cognitiv...

journal_title：Neuropsychiatric disease and treatment

authors： Li S,Zaninotto AL,Neville IS,Paiva WS,Nunn D,Fregni F

更新日期：2015-06-30 00:00:00

abstract：Purpose:Numerous preclinical studies have demonstrated the potential neuroprotective effects of N-acetylcysteine (NAC) in the treatment of brain ischemia. Accordingly, the present study aimed to assess the potential therapeutic effects of oral NAC in patients with acute ischemic stroke. Patients and Methods:In a rando...

journal_title：Neuropsychiatric disease and treatment

authors： Sabetghadam M,Mazdeh M,Abolfathi P,Mohammadi Y,Mehrpooya M

更新日期：2020-05-18 00:00:00

abstract：:Ischemic stroke is one of the leading causes of brain disease, with high morbidity, disability, and mortality. MicroRNAs (miRNAs) have been identified as vital gene regulators in various types of human diseases. Accumulating evidence has suggested that aberrant expression of miRNAs play critical roles in the pathologi...

journal_title：Neuropsychiatric disease and treatment

authors： Yao S,Tang B,Li G,Fan R,Cao F

更新日期：2016-12-05 00:00:00

abstract：BACKGROUND:Deltamethrin (DLM) is a broad-spectrum synthetic dibromo-pyrethroid pesticide that is widely used for agricultural and veterinary purposes. However, human exposure to the pesticide leads to neurotoxicity. Glutamine is one of the principal, free intracellular amino acids and may also be an antioxidant. This s...

journal_title：Neuropsychiatric disease and treatment

authors： Varol S,Özdemir HH,Çevik MU,Altun Y,Ibiloğlu I,Ekinci A,Ibiloğlu AO,Balduz M,Arslan D,Tekin R,Aktar F,Aluçlu MU

更新日期：2016-04-21 00:00:00

abstract：PURPOSE:Akathisia remains a common side effect especially from antipsychotic medication. If the condition is diagnosed the management options are limited. SUBJECTS/METHODOLOGY: We tested a structured relaxation program on nine patients with a diagnosis of schizophrenia suffering from akathisia. All patients were rated ...

journal_title：Neuropsychiatric disease and treatment

authors： Hansen LK,L'allemand T,Thiry F,Baldwin DS

更新日期：2010-05-25 00:00:00

abstract：:Psychiatric and physical conditions often coexist, and there is robust evidence that associates the frequency of depression with single and multiple physical conditions. More than half of patients with depression may have at least one chronic physical condition. Therefore, antidepressants are often used in cotherapy w...

journal_title：Neuropsychiatric disease and treatment

authors： Low Y,Setia S,Lima G

更新日期：2018-02-19 00:00:00

abstract：BACKGROUND:In the current Japanese payment system for the treatment of psychiatric inpatients, the length of hospital stay and nurse staffing levels are key determinants of the amount of payment. These factors do not fully reflect the costs of care for each patient. The objective of this study was to clarify the relati...

journal_title：Neuropsychiatric disease and treatment

authors： Sugibayashi Y,Yoshimura K,Yamauchi K,Inagaki A,Ikegami N

更新日期：2014-08-25 00:00:00

abstract：Purpose:Typically, the diagnosis of conversion motor disorder (CMD) is achieved by the exclusion of a wide range of organic illnesses rather than by applying positive criteria. New diagnostic criteria are highly needed in this scenario. The main aim of this study was to explore the use of behavioral features as an incl...

journal_title：Neuropsychiatric disease and treatment

authors： Pastore A,Pierri G,Fabio G,Ferramosca S,Gigante A,Superbo M,Pellicciari R,Margari F

更新日期：2018-05-18 00:00:00