ppGpp signaling plays a critical role in virulence of Acinetobacter baumannii.

abstract：:The identification of a new T cell subset referred to as T helper 17 (Th17) cells and its role in protective immunity against extracellular bacterial infections is well established. In contrast, initial studies suggested that the IL-23-IL-17 pathway was not required for protection against intracellular pathogens such ...

journal_title：Virulence

authors： Shapiro RS,Cowen L

更新日期：2010-01-01 00:00:00

abstract：:The identification of a new T cell subset referred to as T helper 17 (Th17) cells and its role in protective immunity against extracellular bacterial infections is well established. In contrast, initial studies suggested that the IL-23-IL-17 pathway was not required for protection against intracellular pathogens such ...

journal_title：Virulence

authors： Huang Z,Chai J

更新日期：2010-03-01 00:00:00

abstract：:The identification of a new T cell subset referred to as T helper 17 (Th17) cells and its role in protective immunity against extracellular bacterial infections is well established. In contrast, initial studies suggested that the IL-23-IL-17 pathway was not required for protection against intracellular pathogens such ...

journal_title：Virulence

authors： Click RE,Van Kampen CL

更新日期：2010-05-01 00:00:00

abstract：:The identification of a new T cell subset referred to as T helper 17 (Th17) cells and its role in protective immunity against extracellular bacterial infections is well established. In contrast, initial studies suggested that the IL-23-IL-17 pathway was not required for protection against intracellular pathogens such ...

journal_title：Virulence

authors： Wang Y,Zou H,Fang HM,Zhu Y

更新日期：2010-05-01 00:00:00

abstract：:The identification of a new T cell subset referred to as T helper 17 (Th17) cells and its role in protective immunity against extracellular bacterial infections is well established. In contrast, initial studies suggested that the IL-23-IL-17 pathway was not required for protection against intracellular pathogens such ...

journal_title：Virulence

authors： Joly S,Sutterwala FS

更新日期：2010-07-01 00:00:00

abstract：:The identification of a new T cell subset referred to as T helper 17 (Th17) cells and its role in protective immunity against extracellular bacterial infections is well established. In contrast, initial studies suggested that the IL-23-IL-17 pathway was not required for protection against intracellular pathogens such ...

journal_title：Virulence

authors： Wesolowski J,Paumet F

更新日期：2010-07-01 00:00:00

abstract：:The identification of a new T cell subset referred to as T helper 17 (Th17) cells and its role in protective immunity against extracellular bacterial infections is well established. In contrast, initial studies suggested that the IL-23-IL-17 pathway was not required for protection against intracellular pathogens such ...

journal_title：Virulence

authors： Arenas GN,Grilli DJ,Samartino LE,Magadán J,Mayorga LS

更新日期：2010-09-01 00:00:00

abstract：:The identification of a new T cell subset referred to as T helper 17 (Th17) cells and its role in protective immunity against extracellular bacterial infections is well established. In contrast, initial studies suggested that the IL-23-IL-17 pathway was not required for protection against intracellular pathogens such ...

journal_title：Virulence

authors： Khader SA,Gopal R

更新日期：2010-09-01 00:00:00

abstract：:There is increasing evidence that inflammation or a disturbance of the flora within the gut might contribute to the pathogenesis of irritable bowel syndrome (IBS), at least in a proportion of cases. As a consequence it has been speculated that, as some probiotic bacteria have a range of anti-inflammatory and immunomod...

journal_title：Virulence

authors： Sauerbrei A,Deinhardt S,Zell R,Wutzler P

更新日期：2010-11-01 00:00:00

abstract：:Both Escherichia coli and Streptococcus faecalis grew in an alkaline medium containing 100 microM carbonyl cyanide m-chlorophenylhydrazone (CCCP). Our data suggested that CCCP functioned as a protonophore at a high pH and that the proton-motive force was dissipated almost completely under such conditions. The pH gradi...

journal_title：Virulence

authors： Keeling PJ,Corradi N

更新日期：2011-01-01 00:00:00

abstract：:It has been demonstrated that the presence of cancer results in detectable changes to uninvolved tissues, collectively termed cancer field effects (CFE). In this study, we directly assessed the ability of Raman microspectroscopy to detect CFE via in-vitro study of organotypic tissue rafts approximating human skin. Ram...

journal_title：Virulence

authors： Olsen RJ,Watkins ME,Cantu CC,Beres SB,Musser JM

更新日期：2011-03-01 00:00:00

abstract：:Azithromycin was shown to be as effective as standard benzathine penicillin and erythromycin in the therapy of active syphilis in the rabbit model. Following production of primary chancres by intradermal inoculation of 10(6) Treponema pallidum, groups of six rabbits were treated with benzathine penicillin (200,000 uni...

journal_title：Virulence

authors： Bianco MV,Blanco FC,Forrellad MA,Aguilar D,Campos E,Klepp LI,Hernández-Pando R,Cataldi AA,Bigi F

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVES:To describe older patients' understanding of emergency department (ED) discharge information and to explore the relationship between understanding of ED discharge information and adverse outcomes. METHODS:Telephone interviews were conducted with patients 65 years or older (or their proxies) within 72 hours ...

journal_title：Virulence

authors： Camejo A,Carvalho F,Reis O,Leitão E,Sousa S,Cabanes D

更新日期：2011-09-01 00:00:00

abstract：:Schizophrenia has been associated with an imbalance in inflammatory cytokines. Leukemia inhibitory factor receptor α (LIFR) is an integral component of the glycoprotein 130-LIFR signaling complex, which participates in signal transduction by members of the interleukin (IL)-6 cytokin...

journal_title：Virulence

authors： St Denis TG,Dai T,Izikson L,Astrakas C,Anderson RR,Hamblin MR,Tegos GP

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Minimal access surgery to stage early ovarian cancer (EOC) is still regarded as investigational among many gynecologic oncologists. Reporting outcome data from large cohorts is currently the only practical way to further define the appropriateness of minimally invasive surgery for EOC patients. We sought to ...

journal_title：Virulence

authors： Krachler AM,Ham H,Orth K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The prevalence of traumatic anterior shoulder dislocation in the elderly population has increased; however, no consensus has been reached regarding the management of shoulder dislocations in elderly patients. PURPOSE:This study investigated the clinical manifestations of traumatic anterior shoulder dislocat...

journal_title：Virulence

authors： Federle M

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Brugada syndrome is an arrhythmogenic disease characterized by coved ST segment elevation and J point elevation of at least 2 mm in at least two of the right precordial ECG leads (V1-3) and ventricular arrhythmias, syncope, and sudden death. Risk stratifications of patients with Brugada electrocardiogram a...

journal_title：Virulence

authors： Allam US,Krishna MG,Sen M,Thomas R,Lahiri A,Gnanadhas DP,Chakravortty D

更新日期：2012-03-01 00:00:00

abstract：:Malignant hyperthermia (MH) susceptibility is a dominantly inherited disorder in which volatile anesthetics trigger aberrant Ca(2+) release in skeletal muscle and a potentially fatal rise in perioperative body temperature. Mutations causing MH susceptibility have been identified in two proteins critical for excitation...

journal_title：Virulence

authors： Huang G

更新日期：2012-05-01 00:00:00

abstract：:Sampling plays a major role in quality improvement work. Random sampling (assumed by most traditional statistical methods) is the exception in improvement situations. In most cases, some type of "judgment sample" is used to collect data from a system. Unfortunately, judgment sampling is not well understood. Judgment s...

journal_title：Virulence

authors： Krachler AM,Mende K,Murray C,Orth K

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Angiostrongylus cantonensis (A. cantonensis) is the major cause of infectious eosinophilic meningitis. Dead larvae of this parasite cause inflammation and exacerbate symptoms of meningitis. Corticosteroids are drugs used to reduce inflammation caused by this parasite. OBJECTIVES:To examine the effects and a...

journal_title：Virulence

authors： Hollenbeck BL,Rice LB

更新日期：2012-08-15 00:00:00

abstract：BACKGROUND:Angiostrongylus cantonensis (A. cantonensis) is the major cause of infectious eosinophilic meningitis. Dead larvae of this parasite cause inflammation and exacerbate symptoms of meningitis. Corticosteroids are drugs used to reduce inflammation caused by this parasite. OBJECTIVES:To examine the effects and a...

journal_title：Virulence

authors： Waithman J,Mintern JD

更新日期：2012-11-15 00:00:00

abstract：:Predictions about sensations resulting from motor acts are instantiated through neural mechanisms such as the corollary discharge. With each action, the corollary discharge provides an unconscious comparison between predicted and actual sensations resulting from the action; closer matches result in greater suppression...

journal_title：Virulence

authors： Mihret A

更新日期：2012-11-15 00:00:00

abstract：:Predictions about sensations resulting from motor acts are instantiated through neural mechanisms such as the corollary discharge. With each action, the corollary discharge provides an unconscious comparison between predicted and actual sensations resulting from the action; closer matches result in greater suppression...

journal_title：Virulence

authors： Reed EE,Stevenson KB,West JE,Bauer KA,Goff DA

更新日期：2013-02-15 00:00:00

abstract：:The treatment of chronic skin ulcers with exposed bone in the lower extremity is difficult. The development of topical negative pressure (TNP) technology and microsurgical techniques have achieved good clinical results in the repair of such ulcers. Between January 2007 and March 2012, TNP combined with flap transfer w...

journal_title：Virulence

authors： Sanecka A,Frickel EM

更新日期：2012-11-15 00:00:00

abstract：:Ticks transmit a variety of viral, bacterial and protozoal pathogens, which are often zoonotic. The aim of this study was to identify diverse tick microbiomes, which may contain as-yet unidentified pathogens, using a metagenomic approach. DNA prepared from bacteria/archaea-enriched fractions obtained from seven tick s...

journal_title：Virulence

authors： Chung GW,Wu JE,Yeo CL,Chan D,Hsu LY

更新日期：2013-02-15 00:00:00

abstract：OBJECTIVE:To determine whether smoking reduces the progression of osteoarthritis (OA). METHODS:Observational studies examining smoking and progression of OA were systematically searched through Medline (1948-), EMBase (1980-), Web of Science, PubMed, and Google and relevant references. The search was last updated in M...

journal_title：Virulence

authors： Kamdar K,Nguyen V,DePaolo RW

更新日期：2013-04-01 00:00:00

abstract：:Genetic changes required for the formation and progression of human Schwann cell tumors remain elusive. Using a Sleeping Beauty forward genetic screen, we identified several genes involved in canonical Wnt signaling as potential drivers of benign neurofibromas and malignant peripheral nerve sheath tumors (MPNSTs). In ...

journal_title：Virulence

authors： Richards AM,Von Dwingelo JE,Price CT,Abu Kwaik Y

更新日期：2013-05-15 00:00:00

abstract：:Neuroglobin (Ngb), a neuron-specific heme-binding protein that binds O2, CO and NO reversibly, and promotes in vivo and in vitro cell survival after hypoxic and ischaemic insult. Although the mechanisms of this neuroprotection remain unknown, Ngb might play an important role in counteracting the adverse effects of isc...

journal_title：Virulence

authors： Fortier LC,Sekulovic O

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:Epidemiological studies indicate that obesity is associated with an increased risk of 20-25% with several types of cancer. OBJECTIVE:The frequency of chromosome aberrations was evaluated in lymphocytes from postmenopausal obese and non-obese women. MATERIALS AND METHODS:Twenty obese and 20 non-obese wome...

journal_title：Virulence

authors： Doxey AC,McConkey BJ

更新日期：2013-08-15 00:00:00

abstract：BACKGROUND:Sequence-based phylogenetic trees are a well-established tool for characterizing diversity of both macroorganisms and microorganisms. Phylogenetic methods have recently been applied to shotgun metagenomic data from microbial communities, particularly with the aim of classifying reads. But the accuracy of gen...

journal_title：Virulence

authors： Krachler AM,Orth K

更新日期：2013-05-15 00:00:00